Smoking status over two years in patients with multiple sclerosis.

Abstract:

BACKGROUND:Smoking increases the risk of multiple sclerosis (MS) and possibly disease progression. The reliability of self-reported smoking status is unknown in MS. We assessed the reliability of self-reported smoking status among participants in the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry. METHODS:In 2004 and 2006, NARCOMS participants reported smoking status using Behavioral Risk Factor Surveillance Survey questions. We compared responses from 5,458 participants answering both questionnaires. We measured agreement regarding smoking status (ever/current) using a kappa coefficient, and agreement for ages of starting and quitting smoking, and number of cigarettes smoked using an intraclass correlation coefficient (ICC). RESULTS:In 2004, 2,885 (53.4%) participants reported ever smoking. The kappa coefficient for ever smoking was 0.90 (95% confidence interval, CI: 0.89-0.92) and for current smoking 0.92 (95% CI: 0.90-0.94). The ICC for age at starting smoking was 0.73 (95% CI: 0.71-0.75) and for age at quitting smoking 0.90 (95% CI: 0.89-0.91). African-Americans, younger participants and those of lower socioeconomic status were less reliable. Depressed participants reported current smoking status less consistently (odds ratio: 0.51; 95% CI: 0.39-0.67). CONCLUSIONS:NARCOMS participants reliably report smoking status. The impact of depression on reliability of self-reported smoking status needs re-evaluation.

journal_name

Neuroepidemiology

journal_title

Neuroepidemiology

authors

Marrie RA,Cutter G,Tyry T,Campagnolo D,Vollmer T

doi

10.1159/000170910

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

72-9

issue

1

eissn

0251-5350

issn

1423-0208

pii

000170910

journal_volume

32

pub_type

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