Abstract:
:Mortality rates for deaths 'due to' and 'with' hereditary ataxias are presented for the first time. Age-adjusted mortality rates were higher for whites than for nonwhites of either sex, and for men in both racial groups. Age-specific mortality rates for whites showed a peak for 'hereditary spinal ataxia' in the 20-29 age group. For the other types of ataxias they were low until age 40 and increased thereafter. Heart diseases were a frequent cause of death in people dying 'with' hereditary ataxias. The median survival (from birth) for hereditary spinal ataxia in whites was 35 years.
journal_name
Neuroepidemiologyjournal_title
Neuroepidemiologyauthors
Leone M,Chandra V,Schoenberg BSdoi
10.1159/000110182subject
Has Abstractpub_date
1989-01-01 00:00:00pages
193-9issue
4eissn
0251-5350issn
1423-0208journal_volume
8pub_type
杂志文章abstract:BACKGROUND:Hereditary ataxias (HA) comprise a group of genetically heterogeneous rare diseases. As important public health problems to be monitored, this study analyses the morbimortality of HA in Spain. METHODS:Data were extracted from the national death index (1981-2008), using the International Classification of Di...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000346275
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:Brain tumors are the second most common pediatric malignancy. The literature suggests that one of the most common subtypes of malignant childhood brain tumor, medulloblastoma, has some seasonal variation in incidence by month of birth. METHODS:Data from cases in the Central Brain Tumor Registry of the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109502
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Short-term exposure to high levels of air pollution can increase stroke risk. In this study we investigated the short-term effects of air pollution on hospital admissions for stroke in a setting where pollutant levels are rather low. We also addressed methodological issues in evaluating the short-term effect...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000274807
更新日期:2010-01-01 00:00:00
abstract::Most available data on the prognosis of epileptic seizures come from hospital-based clinics in which patients with chronic or severe disease are over-represented. The National General Practice Study of Epilepsy and Epileptic Seizures is a large prospective community-based study of people with newly diagnosed seizures ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110186
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:In Central/Eastern European countries, cerebrovascular diseases are among the leading causes of mortality. We aimed to determine the incidence of first-ever stroke (FES) in the north-western part of Croatia. METHODS:A population-based prospective incidence study was conducted between July 1, 2007, and June ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000336114
更新日期:2012-01-01 00:00:00
abstract::Infectious viruses and bacteria can trigger multiple sclerosis (MS) exacerbations. Seasonally changing concentrations of ambient air pollutants are known to predispose to transmissible infections, to induce systemic immune responses and to enhance existing peripheral inflammation. Ambient air quality and monthly MS re...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000067108
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Smoking increases the risk of multiple sclerosis (MS) and possibly disease progression. The reliability of self-reported smoking status is unknown in MS. We assessed the reliability of self-reported smoking status among participants in the North American Research Committee on Multiple Sclerosis (NARCOMS) Reg...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000170910
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Previous studies suggested a decreased risk of cancer among patients with Alzheimer's disease (AD). There is still a lack of data on the specific types of cancer, the risk factors, and the impact of cholinesterase inhibitors on developing cancer in AD. METHODS:We performed a nationwide population-based stud...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000341411
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is increasing evidence that the pathophysiologic mechanisms are different between migraine and tension-type headache. The aim of the study was to determine possible sociodemographic differences in Saudi Arabia subjects with headache. METHODOLOGY:A community-based door-to-door survey with i...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109670
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Charcot-Marie-Tooth disease (CMT) is a group of clinically and genetically heterogeneous disorders that primarily affect the peripheral nervous system. Epidemiological studies of CMT have not yet been performed in Korea. OBJECTIVES:This study was performed to estimate the prevalence of CMT in Korea and the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000505815
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Parkinson's disease (PD) is the most common neurodegenerative disease after Alzheimer's dementia. Whereas the exact etiology of PD remains unknown, risk of developing PD seems to be related to a combination of genetic and environmental factors. This also includes abnormal exposure to trace elements of nutrit...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000502357
更新日期:2020-01-01 00:00:00
abstract::This paper describes a proposed study to investigate the incidence of dementia in a population of over 75 year olds in Melton Mowbray, Leicestershire, England. The study population (n = 438) underwent a detailed psychiatric assessment using the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX) as the ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110980
更新日期:1992-01-01 00:00:00
abstract::Previously, we studied the effect of population ancestry on the risk of multiple sclerosis (MS) in US veterans of World War II, comparing by state 1980 US census ancestry data with MS case/control ratios. Here, the joint effects of population ancestry and surname-derived ethnicity on MS risk are examined in the same s...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109804
更新日期:1995-01-01 00:00:00
abstract::The knowledge of the prevalence of spinal cord disorders (SCD) is important to understand specific causes in each part of the worldand to allow to potentially adapt health care and public policy including law enforcement to the main causes. SCD have important personal, biopsychological, socio-economic, short-term and ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000348320
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To determine the age and sex variations in the relationship between diabetes and stroke. METHODS:This analysis was based on data from 61,327 Canadians > or =45 years of age who participated in the Canadian Community Health Survey in 2000-2001. Logistic regression analysis was conducted to evaluate the associ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000097856
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:We aimed to determine the accuracy of the iScore for predicting mortality and early disability following ischemic stroke in a French population-based study. METHODS:All patients with acute ischemic stroke were identified among residents of the city of Dijon, France, between 2006 and 2011, using a population...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000354634
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Exercise is hypothesized to improve cognition, physical performance, functional ability and quality of life, but evidence is scarce. Previous studies were of short duration, often underpowered and involving home-based light exercise programs in patients with undefined dementia. The aim of the ADEX ('Preservi...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000354632
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The goal of this study was to assess the validity of a screening question for head tremor in essential tremor (ET). There are no published data on this topic, and the knowledge will guide future epidemiological investigations of this disorder. METHODS:These analyses utilized four distinct patient samples: a...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000365991
更新日期:2014-01-01 00:00:00
abstract::Homocysteine is a metabolite of methionine that may be remethylated by enzymes requiring folate and cobalamin (vitamin B12) to again form methionine or catabolized by the pyridoxine (vitamin B6) dependent enzyme, cystathionine beta synthase (CBS) to form cysteine (fig. 1) [1]. Homocysteine exists as a combination of v...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
doi:10.1159/000026169
更新日期:1998-01-01 00:00:00
abstract::The epidemiology of multiple sclerosis (MS) in Austria is almost unknown. We evaluated the prevalence of MS in Austria using data from questionnaires completed by neurologists, comprising information on a total of 1,006 MS patients who attended 30 out-patient specialized clinics nationwide. Additional data were collec...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000065640
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Lifespan is 6-10 years shorter in multiple sclerosis (MS), but the reasons remain unclear. Using linked clinical- and population-based administrative health databases, we compared cause-specific mortality in an MS cohort to the general population. METHODS:MS patients in British Columbia (BC), Canada, were f...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000504804
更新日期:2020-01-01 00:00:00
abstract::We studied the prevalence of Parkinson's disease (PD) in Gypsies and Caucasians in Bulgaria. Cases were ascertained by examination in a clinic, a screening questionnaire and a door-to-door survey in a region of Sofia, Bulgaria. The prevalence of PD in the Gypsies was found to be 16/100,000 based on 1 case compared to ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026257
更新日期:2000-07-01 00:00:00
abstract::Iatrogenic Creutzfeldt-Jakob disease (CJD) has never been reported among recipients of dura mater grafts processed in the US. We recently investigated a report of such a case in a 72-year-old man with a typical clinical presentation of CJD. We found no evidence of CJD in either the 34-year-old donor or in other, proxi...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026240
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between hepatitis B (HB) vaccination and a first central nervous system (CNS) demyelinating event in adults. METHODS:In 1998, we conducted a multicentre, hospital-based case-control study which enrolled 402 cases of first CNS demyelinating event occurring between 1994 and 1995...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000059520
更新日期:2002-07-01 00:00:00
abstract:INTRODUCTION:The excess stroke mortality among African Americans and Southerners is well known. Because a higher proportion of the population living in the 'Stroke Belt' is African American, then a portion of the estimated excess risk of stroke death traditionally associated with African-American race may be attributab...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000075954
更新日期:2004-05-01 00:00:00
abstract::White matter lesions (WMLs) detected by cerebral magnetic resonance imaging (MRI) are putatively a consequence of cerebral hypoperfusion or ischemia. We investigated the prevalence, severity and correlates of WMLs in a population-based sample of 1,920 African-American and European-American men and women aged 55-72 yea...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000368814
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous disorder, with a variable reported prevalence ranging from 0.5 to 12 per 100,000. The aim of this retrospective study was to evaluate the prevalence of HSP and estimate the percentage of SPG4 mutations in the Estonian populatio...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000177033
更新日期:2009-01-01 00:00:00
abstract::A strategy for assessing the clinical importance of statistically significant treatment benefits in recent dementia drug trials is proposed. Traditional criteria for the assessment of valid inferences are helpful: the more likely the treatment effects are valid, the greater the chance that they will be clinically impo...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000054761
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Limited epidemiological data exist about amyotrophic lateral sclerosis (ALS) in the United States (US). The Agency for Toxic Substances and Disease Registry maintains the National ALS Registry and funded state and metropolitan surveillance projects to obtain reliable, timely information about ALS in defined ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000365850
更新日期:2014-01-01 00:00:00
abstract::We consider the problem of testing that a disease with variable age at onset is an autosomal dominant or recessive genetic trait. Specific reference is made to Alzheimer's disease and recent publications proposing an autosomal dominant inheritance pattern. The pedigree structure allowed is restricted to first-degree r...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110139
更新日期:1988-01-01 00:00:00