Abstract:
:Risk factors for amyotrophic lateral sclerosis (ALS) such as country of residence, hard labour, intense athletic activities, heavy metal and pet exposure, skeletal trauma, surgical procedures, malignancies, and recurrent infectious disease were investigated in 77 patients and 80 controls, matching the cases for selected parameters, hard work occurred more frequently in ALS patients than in controls; hard labour, skeletal trauma and exposure to heavy metals showed a high relative risk. Some differences were detected in the clinical evolution of ALS, as defined using the Norris scale. These findings support the role of some antecedent events in causing ALS but show that they have little influence on clinical features and disease evolution.
journal_name
Neuroepidemiologyjournal_title
Neuroepidemiologyauthors
Provinciali L,Giovagnoli ARdoi
10.1159/000110782subject
Has Abstractpub_date
1990-01-01 00:00:00pages
255-62issue
5eissn
0251-5350issn
1423-0208journal_volume
9pub_type
杂志文章abstract::We tested the feasibility of a fully automated brain MRI voxel count technique--automated labeling pathway (ALP)--in a sample of 15 demented and 13 cognitively normal women (age 75-85 years) participating to the Cardiovascular Health Study (CHS). We hypothesized that ALP would replicate well-established findings of th...
journal_title:Neuroepidemiology
pub_type: 临床试验,杂志文章
doi:10.1159/000085140
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The goal of this study was to assess the validity of a screening question for head tremor in essential tremor (ET). There are no published data on this topic, and the knowledge will guide future epidemiological investigations of this disorder. METHODS:These analyses utilized four distinct patient samples: a...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000365991
更新日期:2014-01-01 00:00:00
abstract::Many Parkinson's disease (PD) patients treated with levodopa develop motor fluctuations and/or dyskinesia. This large, retrospective study was conducted to compare the prevalence and treatment of dyskinesia in PD patients in seven countries. A total of 380 physicians were interviewed and completed patient record forms...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000111578
更新日期:2007-01-01 00:00:00
abstract::We explored the relationship between amyotrophic lateral sclerosis (ALS) and cigarette smoking in a case-control study conducted in New England from 1993 to 1996. Recently diagnosed ALS cases (n = 109) were recruited from two major referral centers. Population controls (n = 256) were identified by random telephone scr...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026211
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:No epidemiological studies on the prevalence of compressive neuropathy have been undertaken in Arab countries. The aim of the study was to estimate the prevalence of the most common types of compressive neuropathies in Qena governorate/Egypt. METHODS:The study was part of a community-based survey carried ou...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000444641
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:While some personality traits may reduce risk of dementia, this is controversial and has not been studied as much among diverse populations. We examined associations between 2 traits - Conscientiousness and Openness to Experience - and risk of dementia among black and white older adults. METHODS:We studied ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000492821
更新日期:2019-01-01 00:00:00
abstract::Age-related white matter changes (ARWMC) on brain MRI have been associated with cognitive, motor, mood and urinary disturbances. These factors are known to contribute to disability in elderly people, but the impact of ARWMC and of their progression on the transition to disability is not determined. The LADIS (Leukoara...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000081050
更新日期:2005-01-01 00:00:00
abstract::Infectious viruses and bacteria can trigger multiple sclerosis (MS) exacerbations. Seasonally changing concentrations of ambient air pollutants are known to predispose to transmissible infections, to induce systemic immune responses and to enhance existing peripheral inflammation. Ambient air quality and monthly MS re...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000067108
更新日期:2003-01-01 00:00:00
abstract::Since the middle of this century, a remarkable concentration of cases of neurodegenerative disease(s), referred to as amyotrophic lateral sclerosis and Parkinson-dementia complex (ALS/PDC), has been recognized among Chamorro natives of Guam. Intense investigations over the last 4 decades have failed to determine the e...
journal_title:Neuroepidemiology
pub_type: 历史文章,杂志文章,评审
doi:10.1159/000026223
更新日期:1999-01-01 00:00:00
abstract:AIMS:To evaluate the effect of medical record use on figures for the incidence of dementia and the effect of apolipoprotein E (APOE) polymorphism on this incidence and neuropathologically defined Alzheimer's disease (AD) in very elderly individuals. METHODS:Cognitive functions were examined in a cohort of 328 (92% of ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000090252
更新日期:2006-01-01 00:00:00
abstract::Although cognitive screening test scores change with advanced age, the significance of these changes (particularly decline in score) needs to be defined in terms of general health and neuropsychological functioning. Such analysis was undertaken in a subgroup of 287 healthy older men (mean age at baseline = 70.7 years)...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000067113
更新日期:2003-01-01 00:00:00
abstract::Previously, we studied the effect of population ancestry on the risk of multiple sclerosis (MS) in US veterans of World War II, comparing by state 1980 US census ancestry data with MS case/control ratios. Here, the joint effects of population ancestry and surname-derived ethnicity on MS risk are examined in the same s...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109804
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Higher education is associated with a lower risk of dementia, possibly because of a higher tolerance to subclinical neurodegenerative pathology. Whether higher education also protects against dementia after clinical stroke or transient ischemic attack (TIA) remains unknown. METHODS:Within the population-bas...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000443649
更新日期:2016-01-01 00:00:00
abstract::The aim of the study was to evaluate how the natural history of multiple sclerosis (MS) had changed over a 15-year period. We compared disability and mortality in a cohort of 83 MS patients hospitalised in the Neurological Institute of Pavia, northern Italy, from January 1, 1990, to December 31, 1991, with a similar c...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000085308
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Mild cognitive impairment (MCI) has been suggested as a term for a boundary area between normal aging and dementia. This study was designed to determine the prevalence of MCI in the elderly in the Hebei province, China, and explore its related factors. METHODS:Participants included 2,601 community-dwelling ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000357374
更新日期:2014-01-01 00:00:00
abstract::Cerebrovascular diseases (CVDs) constitute the most frequent cause of death in Spain. In order to identify the geographical pattern of CVD mortality, age- and sex-specific as well as age-adjusted mortality rates (ICD-8,9 rubrics 430-438) were calculated for the period 1975-1986 for each province in the country. Maps w...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000109792
更新日期:1995-01-01 00:00:00
abstract::A pilot case-control study was conducted to identify possible risk factors for Meige's syndrome. Patients with Meige's syndrome and age- and sex-matched controls suffering from other neurological diseases were recruited from the Movement Disorders Clinic and Neurology Outpatient Department of the All India Insititute ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026265
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Guillain-Barré syndrome (GBS) is a potentially life-threatening disease that typically occurs after a preceding infectious disease. An accurate estimation of GBS incidence would be useful for investigating the potential causal relationships between risk factors and GBS. Here we described the nationwide incid...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000430917
更新日期:2015-01-01 00:00:00
abstract::We carried out a door-to-door survey in rural areas of the Cordillera Province, Bolivia, to determine the prevalence of the most common neurological diseases in a sample of about 10,000 inhabitants. A team of non-doctor health workers administered a standard screening instrument for neurological diseases, a slightly m...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000048624
更新日期:2002-03-01 00:00:00
abstract::We performed a community-based study on a cohort of 221 stroke patients followed for 3 years. In this paper, we tried to answer the following questions: Is the risk of dying increased throughout the first 3 years after stroke? What are the causes of death after the 1st month? What factors at stroke onset are independe...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000069410
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Transversal studies have underlined the association between the decline in autonomic nervous system (ANS) activity and all-cause mortality. However, the predictive value of ANS has never been prospectively assessed in a general population-based cohort. METHOD:The PROOF (PROgnostic indicator OF cardiovascula...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000108914
更新日期:2007-01-01 00:00:00
abstract::The Canadian Study of Health and Aging (CSHA) provided a population-based estimate of the prevalence of dementia of 8% for those aged 65 and older. Other studies have produced both higher and lower prevalence estimates. Factors that may contribute to these differences include: the use of or the reliance on neuropsycho...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000026247
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Providing a valid and sensitive measure of different domains of cognitive performance in epidemiologic studies of early old-age populations presents a methodological challenge, given the broad range of variability in cognitive functioning in this age group. OBJECTIVES:(1) To provide data on the distribution...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000328262
更新日期:2011-01-01 00:00:00
abstract::In neuroepidemiologic research, there are many pitfalls to trap unwary investigators, whether the project is a survey, a case-control study, or some other type of study. We briefly discuss pitfalls relating to: research preliminaries (e.g., failure to decide on study objectives); personnel and training (e.g., deficien...
journal_title:Neuroepidemiology
pub_type: 杂志文章,评审
doi:10.1159/000026153
更新日期:1998-01-01 00:00:00
abstract::An increased risk for first-degree relatives (FDR) of glioma patients has previously been observed. The novel objective of this study was to investigate differences in familial risk among FDR of low-grade glioma (LGG) and high-grade glioma (HGG) cases, respectively. Two cohorts were constructed, one from 15,321 FDR of...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000065528
更新日期:2002-11-01 00:00:00
abstract::From July 1988 to June 1989, the etiology was registered of 520 patients with generalized neuropathy in 5 neurological centers in Taiwan. The neuropathy was diabetic in 256 cases (49.23%), alcoholic in 45 (8.65%), inflammatory in 34 (6.53%; including 21 with acute inflammatory demyelinating polyneuropathy, 12 with chr...
journal_title:Neuroepidemiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000110326
更新日期:1993-01-01 00:00:00
abstract::In a cooperative study in The Netherlands 22 patients with lissencephaly type I were collected. In the period 1980-1988, the prevalence of lissencephaly type I in the Netherlands was 11.7 per million births (12.2 for females and 11.0 for males). The 5-year survival rate of patients with a complete or nearly complete a...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000110270
更新日期:1991-01-01 00:00:00
abstract::Human neurocysticercosis (NC) is a parasitic disease caused by TAENIA SOLIUM when its larvae lodge in the central nervous system. NC prevalence estimates are obscured by the variable and often asymptomatic clinical picture. While infection depends on exposure, severity is possibly related with various host factors (im...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000068748
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Anthropometric indexes are powerful indicators of the environment and the plasticity of the human body. This study aimed at exploring the anthropometric indexes that are associated with late-life cognition impairment among the elderly Chinese in the Shanghai Aging Study. METHODS:The height, weight, and sitt...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000439569
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To determine the age and sex variations in the relationship between diabetes and stroke. METHODS:This analysis was based on data from 61,327 Canadians > or =45 years of age who participated in the Canadian Community Health Survey in 2000-2001. Logistic regression analysis was conducted to evaluate the associ...
journal_title:Neuroepidemiology
pub_type: 杂志文章
doi:10.1159/000097856
更新日期:2007-01-01 00:00:00