High prevalence of calcified silent neurocysticercosis in a rural village of Mexico.

Abstract:

:Human neurocysticercosis (NC) is a parasitic disease caused by TAENIA SOLIUM when its larvae lodge in the central nervous system. NC prevalence estimates are obscured by the variable and often asymptomatic clinical picture. While infection depends on exposure, severity is possibly related with various host factors (immunity, genes and gender). This epidemiological study of cranial CT scans in an endemic rural community found that 9.1% of apparently healthy subjects had calcified lesions and were completely asymptomatic. Silent NC cases did not correlate with the exposure factors tested but showed family aggregation and higher rates of positive serology. Thus, NC prevalence may be higher than currently considered and host-related factors appear to be involved in infection and pathogenesis.

journal_name

Neuroepidemiology

journal_title

Neuroepidemiology

authors

Fleury A,Gomez T,Alvarez I,Meza D,Huerta M,Chavarria A,Carrillo Mezo RA,Lloyd C,Dessein A,Preux PM,Dumas M,Larralde C,Sciutto E,Fragoso G

doi

10.1159/000068748

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

139-45

issue

2

eissn

0251-5350

issn

1423-0208

pii

68748

journal_volume

22

pub_type

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