From microbes to prions the final proof of the prion hypothesis.

Abstract:

:Much like the "microbe hypothesis" put forth over 150 years ago, the "prion hypothesis" can be definitely proven only if a prion disease is engendered in a natural host from an infectious prion produced in vitro. In this issue of Cell, come very close to accomplishing this goal by producing a prion disease in a natural host from a prion entirely generated in vitro using a PCR-like amplification system.

journal_name

Cell

journal_title

Cell

authors

Zou WQ,Gambetti P

doi

10.1016/j.cell.2005.04.002

subject

Has Abstract

pub_date

2005-04-22 00:00:00

pages

155-7

issue

2

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(05)00343-0

journal_volume

121

pub_type

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