An in vivo study of the host response to starch-based polymers and composites subcutaneously implanted in rats.

abstract：:Tissue damage caused by excessive amounts of neutrophil-derived reactive oxygen species (ROS) occurs in many inflammatory diseases. Butyrate is a short-chain fatty acid (SCFA) with known anti-inflammatory properties, able to modulate several neutrophil functions. Evidence is provided here that butyrate inhibits neutro...

journal_title：Macromolecular bioscience

authors： Sacco P,Decleva E,Tentor F,Menegazzi R,Borgogna M,Paoletti S,Kristiansen KA,Vårum KM,Marsich E

更新日期：2017-11-01 00:00:00

abstract：:This study presents the reactive self-assembly of isocyanate functional and amphiphilic six-arm, star-shaped polyether prepolymers in water into nanogels. Intrinsic molecular amphiphilicity, mainly driven by the isophorone moiety at the distal endings of the star-shaped molecules, allows for the preparation of spheric...

journal_title：Macromolecular bioscience

authors： Hildebrandt H,Paloheimo O,Mäntylä E,Willman S,Hakanen S,Albrecht K,Groll J,Möller M,Vihinen-Ranta M

更新日期：2018-10-01 00:00:00

abstract：:Amino acid ester substituted polyphosphazenes are osteoactive benefiting from their phosphorus-containing chemical structure, which highlights interests in bone tissue engineering. To correlate their chemical structures with cell activities, in this study, poly[(ethyl alanato)0.3 (ethyl glycinato)0.7 phosphazene] (PAG...

journal_title：Macromolecular bioscience

authors： Huang Z,Yang L,Hu X,Huang Y,Cai Q,Ao Y,Yang X

更新日期：2019-06-01 00:00:00

abstract：:Amylose-fatty acid inclusion complexes can be easily prepared by simple mixing in hot aqueous solutions. Above a critical chain length (C6) of the fatty acid insoluble complexes between amylose and each fatty acid (C8, C10, C12, C14, C16) were precipitated from the solution, and characterized by FT-IR, XRD, DSC, and S...

journal_title：Macromolecular bioscience

authors： Cao Z,Woortman AJ,Rudolf P,Loos K

更新日期：2015-05-01 00:00:00

abstract：:Biopolymers are an attractive class of compounds for being used in biomedical applications as they are widely available from biomass. Their drawback is the lack of mechanical stability and the ability to tune this properly. Covalent chemical cross-linking is an often used approach but it limits usability due to legisl...

journal_title：Macromolecular bioscience

authors： Kühn PT,Meijer TL,Schiavon I,van Poll M,van Aken J,Groen S,Kuijer R,van Kooten TG,van Rijn P

更新日期：2016-11-01 00:00:00

abstract：:Novel temperature-sensitive poly(N-isopropylacrylamide)/amine-terminated polyamidoamine dendrimer G6-NH2 hydrogels with fast responsive properties were synthesized by forming semi-interpenetrating polymeric networks. In contrast to the conventional PNIPA hydrogel, these new gels showed rapid shrinking rate at the temp...

journal_title：Macromolecular bioscience

authors： Zhang JT,Huang SW,Zhuo RX

更新日期：2004-06-25 00:00:00

abstract：:Cells in physiological 3D environments differ considerably in morphology and differentiation from those in 2D tissue culture. Naturally derived polymer systems are frequently used to study cells in 3D. These 3D matrices are complex with respect to their chemical composition, mechanical properties, and geometry. Theref...

journal_title：Macromolecular bioscience

authors： Greiner AM,Richter B,Bastmeyer M

更新日期：2012-10-01 00:00:00

abstract：:New data are constantly gathered to show the role of oxidative stress and the involvement of reactive oxygen species in the pathogenesis of degenerative diseases. InsP6 is able to coordinate iron metal in order to prevent iron-catalyzed free radical formation. The aim of the present paper is to describe a new syntheti...

journal_title：Macromolecular bioscience

authors： Iemma F,Trombino S,Puoci F,Cirillo G,Spizzirri UG,Muzzalupo R,Picci N

更新日期：2005-11-04 00:00:00

abstract：:Current approaches to generate core-shell nanoparticles for biomedical applications are limited by factors such as synthetic scalability and circulatory desorption of cytotoxic surfactants. Developments in controlled radical polymerization, particularly in dispersed states, represent a promising method of overcoming t...

journal_title：Macromolecular bioscience

authors： Gurnani P,Sanchez-Cano C,Abraham K,Xandri-Monje H,Cook AB,Hartlieb M,Lévi F,Dallmann R,Perrier S

更新日期：2018-10-01 00:00:00

abstract：:Comb-shaped glycopolymer/peptide bioconjugates are constructed by grafting reduced glutathione (GSH) onto acrylate-functional block glycocopolymers via thiol-ene click chemistry. In aqueous solution, the glycopolymer/GSH bioconjugate self-assembles to sugar-installed spherical micelles. The size of micelles decreases ...

journal_title：Macromolecular bioscience

authors： Wang X,Liu L,Luo Y,Shi H,Li J,Zhao H

更新日期：2012-11-01 00:00:00

abstract：:Polycations, mimicking activity of antibacterial peptides, belong to an important class of molecules investigated as a support or as an alternative to antibiotics. In this work, studies of modified linear amphiphilic statistical polymethyloxazoline (PMOX) and polyethyleneimine copolymers (PMOX_PEI) series are presente...

journal_title：Macromolecular bioscience

authors： Kozon D,Mierzejewska J,Kobiela T,Grochowska A,Dudnyk K,Głogowska A,Sobiepanek A,Kuźmińska A,Ciach T,Augustynowicz-Kopeć E,Jańczewski D

更新日期：2019-12-01 00:00:00

abstract：:Silk fibroin is a useful protein polymer for biomaterials and tissue engineering. In this work, porogen leached scaffolds prepared from aqueous and HFIP silk solutions were reinforced through the addition of silk particles. This led to about 40 times increase in the specific compressive modulus and the yield strength ...

journal_title：Macromolecular bioscience

authors： Rajkhowa R,Gil ES,Kluge J,Numata K,Wang L,Wang X,Kaplan DL

更新日期：2010-06-11 00:00:00

abstract：:Desferrioxamine (DFO) is a clinically approved, high affinity iron chelator used for the treatment of iron overload. Due to its short half-life and toxicity, DFO is administered for 8-12 h per day, 5-7 d per week. In this manuscript, the influence of molecular properties of hyperbranched polyglycerol (HPG)-DFO conjuga...

journal_title：Macromolecular bioscience

authors： Hamilton JL,Ul-Haq MI,Creagh AL,Haynes CA,Kizhakkedathu JN

更新日期：2017-03-01 00:00:00

abstract：:Multicomponent systems for self-assembled molecular gels provide huge opportunities to generate collective or new functions that are not inherent in individual single-component gels. However, gelation tends to require careful and complicated procedures, because, among a myriad of kinetically trapped structures related...

journal_title：Macromolecular bioscience

authors： Hata Y,Kojima T,Maeda T,Sawada T,Serizawa T

更新日期：2020-09-01 00:00:00

abstract：:Microbial transglutaminase (mTG) and mushroom tyrosinase (MT) are used to crosslink B. mori silk fibroin/gelatin (SF/G) films. Crosslinked and uncrosslinked SF/G films show no phase separation. The thermal behavior and the conformational structure of SF/G films are strongly affected by blending and enzymatic treatment...

journal_title：Macromolecular bioscience

authors： Taddei P,Chiono V,Anghileri A,Vozzi G,Freddi G,Ciardelli G

更新日期：2013-11-01 00:00:00

abstract：:Functional hydrophilic microspheres (latex particles) have found various applications in life sciences and in medicine - particularly in latex diagnostic tests. This paper presents a comprehensive review of studies on latex particles with a hydrophilic interfacial layer composed of various hydrophilic polymers with re...

journal_title：Macromolecular bioscience

authors： Basinska T

更新日期：2005-12-15 00:00:00

abstract：:Thermosensitive macroporous scaffolds of poly(N-isopropylacrylamide) (polyNIPA) loaded with chitosan/bemiparin nanoparticles are prepared by the free radical polymerization in cryogenic conditions. Chitosan/bemiparin nanoparticles of 102 ± 6.5 nm diameter are prepared by complex coacervation and loaded into polyNIPA c...

journal_title：Macromolecular bioscience

authors： Peniche H,Reyes-Ortega F,Aguilar MR,Rodríguez G,Abradelo C,García-Fernández L,Peniche C,San Román J

更新日期：2013-11-01 00:00:00

abstract：:Novel chitosan (CHS) and cellulose sulfates (CSs) are studied regarding their mitogenic activity and their protective effect against proteolytic digestion of FGF-2. An intermediate degree of sulfation (DS(S) ) and lower concentration of CHS have superior effect on 3T3 cell growth while the mitogenic activity of CS inc...

journal_title：Macromolecular bioscience

authors： Weltrowski A,da Silva Almeida ML,Peschel D,Zhang K,Fischer S,Groth T

更新日期：2012-06-01 00:00:00

abstract：:The control of biofouling, which is the unwanted adsorption of biomolecules and organisms on solid surfaces, is a prerequisite for wider applicability of the functional materials that are currently being used in biomedical industries. One of the frequently used methods for controlling biofouling is the use of surface ...

journal_title：Macromolecular bioscience

authors： Jeong Y,Thuy LT,Ki SH,Ko S,Kim S,Cho WK,Choi JS,Kang SM

更新日期：2018-10-01 00:00:00

abstract：:Stereolithography-assisted fabrication of hydrogels of carboxybetaine methacrylamide (CBMAA) and a α,ω-methacrylate poly(d,l-lactide-block-ethylene glycol-block- d,l-lactide) (MA-PDLLA-PEG-PDLLA-MA) telechelic triblock macromer is presented. This technique allows printing complex structures with gyroid interconnected ...

journal_title：Macromolecular bioscience

authors： Kostina NY,Blanquer S,Pop-Georgievski O,Rahimi K,Dittrich B,Höcherl A,Michálek J,Grijpma DW,Rodriguez-Emmenegger C

更新日期：2019-04-01 00:00:00

abstract：:The chain length and end groups of linear PEG grafted on smooth surfaces is known to influence protein adsorption and thrombocyte adhesion. Here, it is explored whether established structure function relationships can be transferred to application relevant, rough surfaces. Functionalization of poly(ether imide) (PEI) ...

journal_title：Macromolecular bioscience

authors： Neffe AT,von Ruesten-Lange M,Braune S,Luetzow K,Roch T,Richau K,Jung F,Lendlein A

更新日期：2013-12-01 00:00:00

abstract：:Nanoparticles (NP) represent a promising tool for biomedical applications. Here, sulfonate- and phosphonate-functionalized polystyrene NP are analyzed for their interaction with human monocyte-derived dendritic cells (DC). Immature dendritic cells (iDC) display a higher time- and dose-dependent uptake of functionalize...

journal_title：Macromolecular bioscience

authors： Frick SU,Bacher N,Baier G,Mailänder V,Landfester K,Steinbrink K

更新日期：2012-12-01 00:00:00

abstract：:Interaction of conjugated polymers with liposomes is an attractive approach that benefits from both systems' characteristics such as electroactivity and enhanced interaction with cells. Conjugated polymer-liposome complexes have been investigated for bioimaging, drug delivery, and photothermal therapy. Their fabricati...

journal_title：Macromolecular bioscience

authors： Eslami M,Zeglio E,Alosaimi G,Yan Y,Ruprai H,Macmillan A,Seidel J,Lauto A,Joukhdar H,Rnjak-Kovacina J,Mawad D

更新日期：2020-11-01 00:00:00

abstract：:Pedobacter sp. KP-2 can degrade and metabolize thermally synthesized alpha,beta-poly(D,L-aspartic acid) (tPAA), which contains 70% of unnatural beta-amide units, with high-molecular-weight. In this study, gene cloning and molecular characterization of PAA hydrolase-1 from KP-2 was carried out. Gene analysis reveals th...

journal_title：Macromolecular bioscience

authors： Hiraishi T,Masuda E,Kanayama N,Nagata M,Doi Y,Abe H,Maeda M

更新日期：2009-01-09 00:00:00

abstract：:In many industrial applications, inadequate cell attachment can be a limitation, especially when serum-free media are used. Nitrogen-rich plasma-polymerised ethylene (PPE:N) exhibits high concentrations of polar groups that can help to promote the attachment of weakly adherent cell types. Tissue plasminogen activator-...

journal_title：Macromolecular bioscience

authors： Gigout A,Levasseur S,Girard-Lauriault PL,Buschmann MD,Wertheimer MR,Jolicoeur M

更新日期：2009-10-08 00:00:00

abstract：:The design of a novel polymer-modified overlayer composed of PPAPE and GPMS on a silicon wafer for immobilization of DNA molecules is described. After hydroxylation of Si(100) surfaces, GPMS molecules were self-assembled onto these surfaces. PPAPE molecules were then covalently attached to the epoxy-terminated surface...

journal_title：Macromolecular bioscience

authors： Demirel GB,Coşkun S,Kalkan M,Caykara T

更新日期：2009-05-13 00:00:00

abstract：:Metastasis is a pathogenic spread of cancer cells from the primary site to surrounding tissues and distant organs, making it one of the primary challenges for effective cancer treatment and the major cause of cancer mortality. Heparin-based biomaterials exhibit significant inhibition of cancer cell metastasis. In this...

journal_title：Macromolecular bioscience

authors： Andrgie AT,Mekuria SL,Addisu KD,Hailemeskel BZ,Hsu WH,Tsai HC,Lai JY

更新日期：2019-05-01 00:00:00

abstract：:3D hydrogels better replicate in vivo conditions, and yield different results from 2D substrates. However, imaging interactions between cells and the hydrogel microenvironment is challenging because of light diffraction and poor focal depth. Here, cryosectioning and vibrating microtomy methods and fixation protocols a...

journal_title：Macromolecular bioscience

authors： Short AR,Czeisler C,Stocker B,Cole S,Otero JJ,Winter JO

更新日期：2017-06-01 00:00:00

abstract：:Injectable hydrogels are extensively used in drug delivery and tissue engineering to administer drugs, genes, growth factors and live cells. We report a method to produce tough, in-situ thermogelling, non-toxic, injectable hydrogels made of chitosan and hyaluronic acid co-crosslinked with β-glycerophophate and genipin...

journal_title：Macromolecular bioscience

authors： Jalani G,Rosenzweig DH,Makhoul G,Abdalla S,Cecere R,Vetrone F,Haglund L,Cerruti M

更新日期：2015-04-01 00:00:00

abstract：:Three different microbial wild-type strains are compared with respect to their potential as industrial scale polyhydroxyalkanoate (PHA) producers from the feed stock whey lactose. The halophilic archaeon Haloferax mediterranei as well as two eubacterial strains (Pseudomonas hydrogenovora and Hydrogenophaga pseudoflava...

journal_title：Macromolecular bioscience

authors： Koller M,Hesse P,Bona R,Kutschera C,Atlić A,Braunegg G

更新日期：2007-02-12 00:00:00