Idiopathic hypercalciuria causing osteoporosis and hypocalcemia.

Abstract:

:Idiopathic hypercalciuria, though a common cause of nephrolithiasis, has not been recognized to cause hypocalcemia and severe bone disease. We describe an adolescent with idiopathic hypercalciuria who presented initially with severe hypocalcemia and osteoporosis and this was later complicated by recurrent renal calculi formation after calcium and vitamin D supplement. After treatment with thiazide, hypercalciuria was controlled and serum biochemistry normalized. While idiopathic renal hypercalciuria may cause a negative calcium balance in adults, a variant of this syndrome with severe renal calcium leak occurring in a growing subject could lead to severe hypocalcemia and osteoporosis.

journal_name

Nephron

journal_title

Nephron

authors

Wong CK,Pun KK,Tam SC,Tsui EY,Kung AW,Lam KS,Wang CC

doi

10.1159/000186878

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

224-6

issue

2

eissn

1660-8151

issn

2235-3186

journal_volume

61

pub_type

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