Abstract:
:Idiopathic hypercalciuria, though a common cause of nephrolithiasis, has not been recognized to cause hypocalcemia and severe bone disease. We describe an adolescent with idiopathic hypercalciuria who presented initially with severe hypocalcemia and osteoporosis and this was later complicated by recurrent renal calculi formation after calcium and vitamin D supplement. After treatment with thiazide, hypercalciuria was controlled and serum biochemistry normalized. While idiopathic renal hypercalciuria may cause a negative calcium balance in adults, a variant of this syndrome with severe renal calcium leak occurring in a growing subject could lead to severe hypocalcemia and osteoporosis.
journal_name
Nephronjournal_title
Nephronauthors
Wong CK,Pun KK,Tam SC,Tsui EY,Kung AW,Lam KS,Wang CCdoi
10.1159/000186878subject
Has Abstractpub_date
1992-01-01 00:00:00pages
224-6issue
2eissn
1660-8151issn
2235-3186journal_volume
61pub_type
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