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RNA polymerase II transcribes Dictyostelium untranslatable gene, dutA, specifically in the developmental phase.

Abstract：

:In Dictyostelium discoideum, a novel type of RNA (dutA RNA), which is untranslatable, cytosolic and 1.3 kb in size, appears specifically after the aggregation stage [Yoshida, H. et al. (1994) Nucleic Acids Res. 22, 41-46]. We here show that the dutA gene is transcribed by RNA polymerase II, based on its alpha-amanitin sensitive nature of in vitro transcriptional activity. We also show that the stage-specific accumulation of dutA RNA is primarily due to the stage-specific enhancement of the transcriptional activity of the gene.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Kumimoto H,Yoshida H,Okamoto K

doi

10.1006/bbrc.1995.2620

subject

Has Abstract

pub_date

1995-11-02 00:00:00

pages

273-8

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(85)72620-4

journal_volume

216

pub_type

杂志文章

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