Autocrine effect of endothelin on DNA synthesis in human vascular endothelial cells.

abstract：:Mycoplasma fermentans has been suspected as one of the causative pathogenic microorganisms of rheumatoid arthritis (RA) however, the pathogenic mechanism is still unclear. We, previously, reported that glycolipid-antigens (GGPL-I and III) are the major antigens of M. fermentans. Monoclonal antibody against the GGPL-II...

journal_title：Biochemical and biophysical research communications

authors： Kawahito Y,Ichinose S,Sano H,Tsubouchi Y,Kohno M,Yoshikawa T,Tokunaga D,Hojo T,Harasawa R,Nakano T,Matsuda K

更新日期：2008-05-02 00:00:00

abstract：:Cancer metastasis involves tumor cells invading the surrounding tissue. Remodeling of tissue barriers depends on the ability of tumor cells to degrade the surrounding collagen matrix and then migrate through the matrix defects. Epidermal growth factor (EGF) has been shown to regulate tumor cell invasion through activa...

journal_title：Biochemical and biophysical research communications

authors： Binker MG,Binker-Cosen AA,Richards D,Oliver B,Cosen-Binker LI

更新日期：2009-02-06 00:00:00

abstract：:During the acute phase response, synthesis of C-reactive protein and serum amyloid A is increased. To investigate whether the enhanced synthesis of these proteins are due to stimulatory effect of inflammatory mediators such as interleukin-1 (IL-1) and interleukin-6 (IL-6) produced by macrophages and monocytes, primary...

journal_title：Biochemical and biophysical research communications

authors： Moshage HJ,Roelofs HM,van Pelt JF,Hazenberg BP,van Leeuwen MA,Limburg PC,Aarden LA,Yap SH

更新日期：1988-08-30 00:00:00

abstract：:We examined the effect of low density lipoprotein (LDL) on histamine release from purified human lung mast cells. LDL inhibited anti-IgE- induced histamine release in a dose-dependent manner, with 100 micrograms/ml LDL-protein inhibiting histamine release by 53 +/- 8% (mean +/- SEM); half-maximal inhibition occurred a...

journal_title：Biochemical and biophysical research communications

authors： Schulman ES,Quinn TJ,Post TJ,O'Donnell P,Rodriguez A,Gonen B

更新日期：1987-10-29 00:00:00

abstract：:Dysfunction of Girdin plays a crucial role in the development of a variety of tumors. Phosphorylated regulation of Girdin has been studied extensively. However, how Girdin is dephosphorylated remains unclear. In this study, we report a mechanism of Girdin dephosphorylation and the importance of this mechanism in the m...

journal_title：Biochemical and biophysical research communications

authors： Li J,Enomoto A,Weng L,Sun L,Takahashi M

更新日期：2019-05-21 00:00:00

abstract：:The molecular structures of enzyme mimics may be modified to optimize their catalytic properties. In this study, to generate artificial enzyme mimics, Watson-Crick base paired DNA duplexes were designed as scaffolds which were assembled by nucleotides modified with specific functional groups. This process allowed vari...

journal_title：Biochemical and biophysical research communications

authors： Xu L,Ji C,Bai Y,He J,Liu K

更新日期：2013-05-10 00:00:00

abstract：:Dexamethasone produced an increased activity of stearoyl-CoA desaturase through the enhancement of delta 9-terminal component activity, and a corresponding decrease of oleoyl-CoA desaturase activity via the reduced activity of delta 12-terminal component in Tetrahymena microsomes. However, the content of cytochrome b5...

journal_title：Biochemical and biophysical research communications

authors： Umeki S,Nozawa Y

更新日期：1984-02-29 00:00:00

abstract：:The effects of high (28mM) D-glucose (HG) on the cell cycle progression were investigated in rat aorta vascular smooth muscle cells (VSMCs) in primary culture, using an immunocytochemical analysis of cell-cycle-specific nuclear antigens. HG had no effect on the cell cycle of the serum-deprived G0 cells, whereas platel...

journal_title：Biochemical and biophysical research communications

authors： Hiroishi G,Kobayashi S,Nishimura J,Inomata H,Kanaide H

更新日期：1995-06-15 00:00:00

abstract：:Chemiluminescence in visible region was detected, during peroxidase-catalyzed oxidation of chlorpromazine at pH7.5 (but not at pH4.25) or of propericiazine, both at pH7.5 and at pH4.25. Red colored intermediates, cation radicals, were produced and decayed in all enzymatic systems used. Chemiluminescence was also detec...

journal_title：Biochemical and biophysical research communications

authors： Nakano M,Sugioka K,Nakano H,Takyu C,Inaba H

更新日期：1985-08-15 00:00:00

abstract：:The family of peptidoglycan recognition proteins (PGRPs) is conserved from insects to mammals. Recently, Drosophila PGRP-SC1B was demonstrated to be an N-acetylmuramoyl-L-alanine amidase (NAMLAA), an enzyme that cleaves the lactylamide bond between muramic acid and the peptide chain in peptidoglycan (PGN). We now show...

journal_title：Biochemical and biophysical research communications

authors： Gelius E,Persson C,Karlsson J,Steiner H

更新日期：2003-07-11 00:00:00

abstract：:Modern proteomics approaches include techniques to examine the expression, localization, modifications, and complex formation of proteins in cells. In order to address issues of protein function in vitro using classical biochemical and biophysical approaches, high-throughput methods of cloning the appropriate reading ...

journal_title：Biochemical and biophysical research communications

authors： Huang RY,Boulton SJ,Vidal M,Almo SC,Bresnick AR,Chance MR

更新日期：2003-08-08 00:00:00

abstract：:Actions of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on all-trans-retinoic acid (trans-RA) binding to retinoic acid receptors (RARs) in cultured human keratinocytes (SCC-12F) was investigated. TCDD and trans-RA elicited opposing actions on the production of biologically active TGF-beta. TCDD exposure caused concentra...

journal_title：Biochemical and biophysical research communications

authors： Lorick KL,Toscano DL,Toscano WA Jr

更新日期：1998-02-24 00:00:00

abstract：:Fluorogenic substrates for endopeptidases are often prepared by attaching fluorophores and quenchers to opposite ends of the peptide substrates. Here, we describe a new approach by incorporating tryptophan and p-nitrophenylalanine into peptides to give fluorogenic substrates composed entirely of alpha-amino acids. Two...

journal_title：Biochemical and biophysical research communications

authors： Wang W,Liang TC

更新日期：1994-06-15 00:00:00

abstract：:We report the characterization of a new member of the low-density lipoprotein receptor (LDLR) gene family designated LRP10. Human LRP10 cDNA encodes a 1905 amino acid type I membrane protein consisting of five functional domains characteristic of the LDLR gene family. CHO-ldlA7 cells transfected with human LRP10 cDNA ...

journal_title：Biochemical and biophysical research communications

authors： Jeong YH,Ishikawa K,Someya Y,Hosoda A,Yoshimi T,Yokoyama C,Kiryu-Seo S,Kang MJ,Tchibana T,Kiyama H,Fukumura T,Kim DH,Saeki S

更新日期：2010-01-01 00:00:00

abstract：:The coat proteins of the leafhopper transmitted gemini viruses, viz., maize streak virus and wheat dwarf virus that contain a single circle of DNA in their genomes are shown to bear good amino acid sequence homology with the coat protein of an RNA plant virus, the satellite tobacco necrosis virus. It is suggested that...

journal_title：Biochemical and biophysical research communications

authors： Mohana Rao JK

更新日期：1986-01-14 00:00:00

abstract：:Cathepsin D, a lysosomal aspartic proteinase, has been shown to induce apoptosis of HeLa cells when overexpressed. To further understand regulatory mechanisms of cathepsin D-induced cell death, we examined whether lysosomal cysteine and aspartic proteinases are involved in apoptosis of PC12 cells following serum depri...

journal_title：Biochemical and biophysical research communications

authors： Shibata M,Kanamori S,Isahara K,Ohsawa Y,Konishi A,Kametaka S,Watanabe T,Ebisu S,Ishido K,Kominami E,Uchiyama Y

更新日期：1998-10-09 00:00:00

abstract：:T Kininogen and High Molecular Weight Kininogen were characterized in the cell culture medium of Fao cells, a highly differentiated cell line derived from the Reuber H35 rat hepatoma. Immunoreactive T Kininogen and High Molecular Weight Kininogen identified by direct and specific RIAs were indistinguishable from stand...

journal_title：Biochemical and biophysical research communications

authors： Baussant T,Michaud A,Bouhnik J,Savoie F,Alhenc-Gelas F,Corvol P

更新日期：1988-08-15 00:00:00

abstract：:Many CARD-containing caspase mediators interact with CARD-containing caspases and participate in activation or suppression of caspases. We cloned a novel CARD-containing protein from our EST database, named CARP. Computational characterization revealed that CARP encoded 445 amino acids with predicted MW 49.7 kDa, loca...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Liu Y,Chen J,Wei Z,Yu H,Zhen Y,Lu L,Hui R

更新日期：2002-05-24 00:00:00

abstract：:Novel conformation-specific antibodies were raised against a cyclic chimeric dodecapeptidyl multiple antigen peptide (cCD-MAP) constructed with a spacer-armed Gly-Asp dipeptide and two pentapeptides (S(169)-Q(170)-K(171)-E(172)-G(173) of CCR5 and E(179)-A(180)-D(181)-D(182)-R(183) of CXCR4) which are components of the...

journal_title：Biochemical and biophysical research communications

authors： Misumi S,Takamune N,Ido Y,Hayashi S,Endo M,Mukai R,Tachibana K,Umeda M,Shoji S

更新日期：2001-08-03 00:00:00

abstract：:Previous reports have shown that 12-0-tetradecanoylphorbol-13-acetate can activate phospholipase D in human peripheral blood mononuclear cells as measured by an enzyme-catalyzed transphosphatidylation reaction (phosphatidylethanol formation). In the present study, the mononuclear cells were fractionated by two procedu...

journal_title：Biochemical and biophysical research communications

authors： Kinsky SC,Loader JE,Benedict SH

更新日期：1989-07-31 00:00:00

abstract：:Autophosphorylation of CaM-kinase II produces a form of the enzyme not requiring Ca(2+)/calmodulin for sustained activity. We report that autophosphorylated CaM-kinase II dephosphorylates itself in the presence of ADP (termed autodephosphorylation). The dephosphorylation was unaffected by phosphatase inhibitors and wa...

journal_title：Biochemical and biophysical research communications

authors： Kim SA,Hudmon A,Volmer A,Waxham MN

更新日期：2001-04-06 00:00:00

abstract：:Inflammatory bowel disease (IBD) comprises two major subtypes, ulcerative colitis (UC) and Crohn's disease, which are multifactorial diseases that may develop due to genetic susceptibility, dysbiosis, or environmental factors. Environmental triggers of IBD include food-borne factors, and a previous nationwide survey i...

journal_title：Biochemical and biophysical research communications

authors： Tsuchiya M,Ito G,Hama M,Nagata S,Kawamoto A,Suzuki K,Shimizu H,Anzai S,Takahashi J,Kuno R,Takeoka S,Hiraguri Y,Sugihara HY,Mizutani T,Yui S,Oshima S,Tsuchiya K,Watanabe M,Okamoto R

更新日期：2021-01-20 00:00:00

abstract：:The complete covalent structure of the gamma 2 subunit of bovine brain G proteins was determined by peptide mapping using matrix-assisted laser desorption ionization and electrospray ionization mass spectrometry and by partial sequencing using tandem mass spectrometry. Fragments were identified in proteolytic digests ...

journal_title：Biochemical and biophysical research communications

authors： Wilcox MD,Schey KL,Busman M,Hildebrandt JD

更新日期：1995-07-17 00:00:00

abstract：:MicroRNAs (miRNAs) are small noncoding RNAs that regulate target gene expression through translation repression or messenger RNA degradation. MiR-15a and 16-1 form a cluster at the chromosomal region 13q14, which is frequently deleted or down-regulated in chronic lymphocytic leukemia. Arsenic trioxide (As(2)O(3), ATO)...

journal_title：Biochemical and biophysical research communications

authors： Gao SM,Chen C,Wu J,Tan Y,Yu K,Xing CY,Ye A,Yin L,Jiang L

更新日期：2010-12-10 00:00:00

abstract：:aDNA extraction and amplification procedures have been optimized for Pompeian human bone remains whose diagenesis has been determined by histological analysis. Single copy genes amplification (X and Y amelogenin loci and Y specific alphoid repeat sequences) have been performed and compared with anthropometric data on ...

journal_title：Biochemical and biophysical research communications

authors： Cipollaro M,Di Bernardo G,Galano G,Galderisi U,Guarino F,Angelini F,Cascino A

更新日期：1998-06-29 00:00:00

abstract：:Activated vascular endothelium inflammation under persistent hyperlipidemia is the initial step of atherogenesis. ATP-binding cassette G1 (ABCG1) is a crucial factor maintaining sterol and lipid homeostasis by transporting cholesterol efflux to high-density lipoprotein. In this study, we investigated the protective ef...

journal_title：Biochemical and biophysical research communications

authors： Xue S,Wang J,Zhang X,Shi Y,Li B,Bao Q,Pang W,Ai D,Zhu Y,He J

更新日期：2016-08-19 00:00:00

abstract：:Hepatitis B virus X protein (HBx protein), which seems to be involved in hepatocarcinogenesis, was studied for its effect on cell growth regulation. We examined the response to growth inhibition of transforming growth factor beta 1 (TGF-beta 1) in HBx gene-introduced cells. HBx gene in pRc/CMV was transfected to mink ...

journal_title：Biochemical and biophysical research communications

authors： Oshikawa O,Tamura S,Kawata S,Ito N,Tsushima H,Kiso S,Matsuda Y,Yamada A,Tamai S,Matsuzawa Y

更新日期：1996-05-24 00:00:00

abstract：:Oxidants and inflammatory mediators such as tumour necrosis factor-alpha (TNF-alpha) activate transcription factors such as NF-kappa B. Interleukin-8 (IL-8) is a ubiquitous inflammatory chemokine that mediates a multitude of inflammatory events in the lung. Ergothioneine is a naturally occurring thiol compound, which ...

journal_title：Biochemical and biophysical research communications

authors： Rahman I,Gilmour PS,Jimenez LA,Biswas SK,Antonicelli F,Aruoma OI

更新日期：2003-03-21 00:00:00

abstract：:Three mRNA species for human muscle phophofructokinase containing heterogeneous 5' untranslated sequences were identified through cDNA cloning. Type A mRNA was essentially the same as that reported previously (Nakajima, H., et al. (1987) FEBS Lett. 223, 113). Type B mRNA was considered to be the major gene product, wh...

journal_title：Biochemical and biophysical research communications

authors： Nakajima H,Yamasaki T,Noguchi T,Tanaka T,Kono N,Tarui S

更新日期：1990-01-30 00:00:00

abstract：:Several populations of stem cells, including those from the dental pulp and periodontal ligament, have been isolated from different parts of the tooth and periodontium. The characteristics of such stem cells have been reported as well. However, as a common progenitor of these cells, ectomesenchymal stem cells (EMSCs),...

journal_title：Biochemical and biophysical research communications

authors： Wen X,Liu L,Deng M,Zhang L,Liu R,Xing Y,Zhou X,Nie X

更新日期：2012-10-12 00:00:00