Abstract:
:This study tested the effect on intracranially injected cycloheximide (CHX), an inhibitor of protein synthesis, on facilitation of sexual receptivity in ovariectomized rats. The rats received 0.5 microgram estradiol benzoate (EB), s.c. once daily on days 8 through 12 after ovariectomy (OVX). Either CHX (in 0.5 microliter saline) or 0.5 microliter saline was injected into the lateral septum (LS), cortical nucleus (ACO) or medial nucleus of the amygdala or medial preoptic area on day 11 after OVX. The dose of EB was insufficient to facilitate lordotic behavior on day 10 or day 12 after OVX unless CHX was injected into the LS or ACO. Injection of saline did not influence lordosis.
journal_name
Brain Resjournal_title
Brain researchauthors
Renner KJ,Bast JD,Purcell ES,Quadagno DMdoi
10.1016/0006-8993(81)91050-7subject
Has Abstractpub_date
1981-10-19 00:00:00pages
432-6issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(81)91050-7journal_volume
222pub_type
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