Effects of fluoride on human enamel and selachian enameloid in vitro: a high-resolution TEM and electron diffraction study.

abstract：:A 56 year-old man with a 2-year history of transitional-cell carcinoma of the urinary bladder presented with back pain and diffuse radiological osteosclerosis. Laboratory studies revealed borderline-low ionized serum calcium, and markedly elevated serum alkaline phosphatase (ALP) activity and serum osteocalcin. Serum ...

journal_title：Calcified tissue international

authors： Liel Y,Maor E,Ariad S,Lowenthal MN

更新日期：1998-12-01 00:00:00

abstract：:To test the hypothesis that the relationship between fat mass (FM) and bone mineral density (BMD) is mediated by leptin. The study involved 611 individuals aged 20-89 years who were randomly sampled from Ho Chi Minh City (Vietnam). BMD at the femoral neck (FN), lumbar spine (LS), and whole body (WB) was measured by DX...

journal_title：Calcified tissue international

authors： Ho-Pham LT,Lai TQ,Nguyen UD,Bui QV,Nguyen TV

更新日期：2017-01-01 00:00:00

abstract：:Whole enamel scrapings from unerupted teeth of embryonic calves have been separated into fractions of varying density by stepwise centrifugation in bromoform-toluene mixtures of increasing specific gravity. Partition of enamel in this manner yields individual fractions of increasing mineral phase age and maturation. W...

journal_title：Calcified tissue international

authors： Landis WJ,Navarro M

更新日期：1983-01-01 00:00:00

abstract：:We have examined the effect of the anti-tumor compound taxol, on osteoclastic bone resorption. In the bone slice assay, taxol (0.1-0.001 microM) dose-dependently inhibited bone resorption with an IC50 of 0.08 microM. Osteoclast survival on bone slices was unaffected by 0.01-1 microM taxol, but 10 microM was cytotoxic....

journal_title：Calcified tissue international

authors： Hall TJ,Jeker H,Schaueblin M

更新日期：1995-12-01 00:00:00

abstract：:The gut microbiota (GM) is the whole of commensal, symbiotic, and pathogenic microorganisms living in our intestine. The GM-host interactions contribute to the maturation of the host immune system, modulating its systemic response. It is well documented that GM can interact with non-enteral cells such as immune cells,...

journal_title：Calcified tissue international

authors： D'Amelio P,Sassi F

更新日期：2018-04-01 00:00:00

abstract：:Sclerostin and parathyroid hormones are strong negative and positive regulators of bone formation, respectively. The anabolic response induced by intermittent (iPTH) treatment is sclerostin status-dependent. However, the interaction between sclerostin and iPTH at the matrix level is unknown. The goal of the current st...

journal_title：Calcified tissue international

authors： Ross RD,Mashiatulla M,Robling AG,Miller LM,Sumner DR

更新日期：2016-02-01 00:00:00

abstract：:Several phosphoprotein preparations (phosvitin, rat incisor and fetal calf molar dentin phosphoproteins) all inhibit apatite growth/replication from pre-existing crystal seeds in metastable solutions. Two stages of the crystal growth process were inhibited by these phosphoproteins. First an initial lag period was indu...

journal_title：Calcified tissue international

authors： Termine JD,Eanes ED,Conn KM

更新日期：1980-01-01 00:00:00

abstract：:The effects of the trace metals zinc (Zn), manganese (Mn), and cadmium (Cd) on the metabolism of growth plate chondrocytes was examined using a mineralizing culture system. Supplementation of serum-free primary cultures of growth plate chondrocytes with 10-100 mu m Zn resulted in an increase in cell protein and greatl...

journal_title：Calcified tissue international

authors： Litchfield TM,Ishikawa Y,Wu LN,Wuthier RE,Sauer GR

更新日期：1998-04-01 00:00:00

abstract：:Genome-wide association studies (GWAS) have demonstrated that genetic variation at the MADS box transcription enhancer factor 2, polypeptide C (MEF2C) locus is robustly associated with bone mineral density, primarily at the femoral neck. MEF2C is a transcription factor known to operate via the Wnt signaling pathway. O...

journal_title：Calcified tissue international

authors： Johnson ME,Deliard S,Zhu F,Xia Q,Wells AD,Hankenson KD,Grant SF

更新日期：2014-04-01 00:00:00

abstract：:Icariin, the main constituent of Herba Epimedii, appears to be a promising alternative to classic drugs used to treat osteoporosis. However, the detailed molecular mechanisms of its action and the role of icariin in the cross-talk between osteoblasts and adipocytes remain unclear. The present study was designed to inv...

journal_title：Calcified tissue international

authors： Zhang D,Fong C,Jia Z,Cui L,Yao X,Yang M

更新日期：2016-08-01 00:00:00

abstract：:Although treatment with intranasal salmon calcitonin (sCT) has been shown to effectively inhibit postmenopausal bone loss, there is still controversy over both timing and the duration of its application. In an open prospective study, we therefore assessed the effect of shortterm intranasal sCT on postmenopausal bone t...

journal_title：Calcified tissue international

authors： Kraenzlin ME,Seibel MJ,Trechsel U,Boerlin V,Azria M,Kraenzlin CA,Haas HG

更新日期：1996-04-01 00:00:00

abstract：:Unfixed, undecalcified sections from closed fractures of rat metatarsals have been studied by quantitative cytochemistry from the first week after fracture to late in the fracture-healing process. Alkaline phosphatase activity appeared to be related to calcification. Glucose 6-phosphate dehydrogenase activity was asso...

journal_title：Calcified tissue international

authors： Dunham J,Catterall A,Bitensky L,Chayen J

更新日期：1983-01-01 00:00:00

abstract：:A 69-year-old man became hypocalcemic under medical observation. The hypocalcemia occurred in the presence of circulating immunoreactive parathyroid hormone (PTH). Common causes of secondary hyperparathyroidism were excluded, as was PTH resistance using PTH infusions. The immunoreactive PTH was examined in detail. PTH...

journal_title：Calcified tissue international

authors： McElduff A,Lackmann M,Wilkinson M

更新日期：1992-08-01 00:00:00

abstract：:Twenty boys were followed during their puberty for about 2 years with examinations every third month. At each examination we determined serum concentrations of 25OHD3, 1,25(OH)2D3, 24,25(OH)2D3, 25.26(OH)2D3, alkaline phosphatase (AP) and testosterone together with bone mineral content (BMC) at the distal forearm. Hig...

journal_title：Calcified tissue international

authors： Krabbe S,Christiansen C,Hummer L

更新日期：1986-03-01 00:00:00

abstract：:A case-control study was undertaken to understand the etiopathology of the bone deformities among young children in a fluoride-affected village of the Bihar State. Two villages were selected: one village with high fluoride in drinking water (7.9 +/- 4.15 ppm), and the other village with normal levels of fluoride (0.6 ...

journal_title：Calcified tissue international

authors： Khandare AL,Harikumar R,Sivakumar B

更新日期：2005-06-01 00:00:00

abstract：:The DMS Lexxos is the first cone-beam dual X-ray absorptiometry (DXA) system capable of performing bone mineral density (BMD) measurements of the spine and hip. By using a two-dimensional (2-D) detector array rather than the linear array used with conventional fan-beam DXA systems, image acquisition time on Lexxos is ...

journal_title：Calcified tissue international

authors： Blake GM,Knapp KM,Fogelman I

更新日期：2005-02-01 00:00:00

abstract：:Alkaline phosphatase is detected in both soluble and particulate fractions of rat bone. The concentration of alkaline phosphatase in the particulate fraction of rat skull cap bone and femur is high during the peak period of calcification of these bones suggesting the possibility of using it as a marker for the rate of...

journal_title：Calcified tissue international

authors： Murthy GP,Rajalakshmi R,Ramakrishnan CV

更新日期：1986-09-01 00:00:00

abstract：:The present study was undertaken to determine the fluoride distribution profile in the rat femur. Male Wistar rats were divided into four groups and given water containing 0, 25, 50, and 100 ppm of fluoride, respectively, for 10 weeks. The fluoride distribution from the periosteum to the endosteum was determined in ea...

journal_title：Calcified tissue international

authors： Narita N,Kato K,Nakagaki H,Ohno N,Kameyama Y,Weatherell JA

更新日期：1990-03-01 00:00:00

abstract：:This study aims to test the hypothesis that noninvasive bone mass measurements can be used to predict bone strength in a piglet model. Dual energy X-ray absorptiometry measurements of bone mineral content (BMC), bone mineral density (BMD), and bone area (BA) were obtained from four sets of bones (left and right humeri...

journal_title：Calcified tissue international

authors： Koo MW,Yang KH,Begeman P,Hammami M,Koo WW

更新日期：2001-04-01 00:00:00

abstract：:Data on the association between dietary vitamin K intake and fracture risk are limited among Chinese. This study examined such an association in community-dwelling elderly in Hong Kong. We present data from 2,944 subjects (1,605 men, 1,339 women) who participated in a prospective cohort study. Baseline dietary intakes...

journal_title：Calcified tissue international

authors： Chan R,Leung J,Woo J

更新日期：2012-05-01 00:00:00

abstract：:Pleiotrophin (PTN) was found to have potent effects on regulation of osteoblast recruitment, proliferation and differentiation. The present study examined the long-term effects of targeted PTN over-expression on bone development and repair in a transgenic mouse model. Femurs and tibiae from the PTN transgenic mice and...

journal_title：Calcified tissue international

authors： Li G,Bunn JR,Mushipe MT,He Q,Chen X

更新日期：2005-04-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is commonly used in the assessment of the musculoskeletal system and associated pathology. The ability of MRI to measure the signals from water and lipid protons enables quantitative measurements of bone porosity. The goal of this investigation was to demonstrate that the density and c...

journal_title：Calcified tissue international

authors： Hong J,Hipp JA,Mulkern RV,Jaramillo D,Snyder BD

更新日期：2000-01-01 00:00:00

abstract：:Previous studies have indicated that children with inflammatory bowel disease (IBD) may not achieve optimal bone mass. We evaluated the skeletal characteristics in children and adolescents with IBD. This cross-sectional cohort study comprised 80 IBD patients (median age 14.9 years, range 5-20) with a median disease du...

journal_title：Calcified tissue international

authors： Laakso S,Valta H,Verkasalo M,Toiviainen-Salo S,Viljakainen H,Mäkitie O

更新日期：2012-08-01 00:00:00

abstract：:Recent evidence of the occurrence of brushite in newly formed bone mineral prompted a study of the solubility properties of brushite:apatite mixtures under physiological conditions and the influence on them of pH, lactate, pyruvate, and, particularly, noncollagenous bone proteins (NCBPs). Brushite alone was surprising...

journal_title：Calcified tissue international

authors： Neuman WF,Neuman MW,Diamond AG,Menanteau J,Gibbons WS

更新日期：1982-03-01 00:00:00

abstract：:Connective tissue diseases, including osteogenesis imperfecta (OI) and Ehlers-Danlos syndrome (EDS), exhibit a high degree of clinical and genetic heterogeneity. We report two sisters with blue sclerae, joint hypermobility and hearing loss. Whole-exome sequencing identified two compound heterozygous ZNF469 loss-of-fun...

journal_title：Calcified tissue international

authors： Rolvien T,Kornak U,Linke SJ,Amling M,Oheim R

更新日期：2020-09-01 00:00:00

abstract：:We studied the epidemiology of osteoporotic fractures of the proximal femur (cervical and trochanteric fractures) in residents of Barcelona, aged 45 years or over, for a 1-year period. Fractures resulting from metastases were not included. During the period of observation, a total of 1,358 patients with hip fractures ...

journal_title：Calcified tissue international

authors： Diez A,Puig J,Martinez MT,Diez JL,Aubia J,Vivancos J

更新日期：1989-06-01 00:00:00

abstract：:Radiation therapy (RT) is an established treatment modality for malignant neoplasms. RT induces tissue damage that may lead to osteoradionecrosis in more severe cases. Suitable animal models to study RT-induced changes in membranous craniofacial bone are currently not available. The aim of this study was therefore to ...

journal_title：Calcified tissue international

authors： Desmons S,Heger M,Delfosse C,Falgayrac G,Sarrazin T,Delattre C,Catros S,Mordon S,Penel G

更新日期：2009-05-01 00:00:00

abstract：:Osteoblast differentiation is predominantly regulated by the WNT/β-catenin signaling (canonical WNT pathway), which, together with bone morphogenetic proteins, acts as the master regulator of osteogenesis. The recent characterization of the canonical WNT pathway in the regulation of bone modeling and remodeling provid...

journal_title：Calcified tissue international

authors： Rossini M,Gatti D,Adami S

更新日期：2013-08-01 00:00:00

abstract：:Osteoarthritis (OA), the most prevalent chronic joint disease, increases in prevalence with age, and affects majority of individuals over the age of 65 and is a leading musculoskeletal cause of impaired mobility in the elderly. Because the precise molecular mechanisms which are involved in the degradation of cartilage...

journal_title：Calcified tissue international

authors： Xia B,Di Chen,Zhang J,Hu S,Jin H,Tong P

更新日期：2014-12-01 00:00:00

abstract：:1,25 Dihydroxyvitamin D3 (1,25(OH)2D3) (2.0 micrograms) was given intramuscularly to 6 healthy adult males. Twenty-four circadian patterns of blood-ionized calcium (Ca2+), serum phosphate (Pi), and total calcium (CaT) were assessed pre- and posthormone administration. Correlations of mean mineral rhythms with normativ...

journal_title：Calcified tissue international

authors： Markowitz ME,Rosen JF,Mizruchi M

更新日期：1985-07-01 00:00:00