Taxol inhibits osteoclastic bone resorption.

abstract：:Binding sites for wheat germ agglutinin (WGA)-lectin have been shown to become revealed in the demineralized resorption lacunae that osteoclasts excavate on bone substrate. Peroxidase-conjugated WGA-lectin, which binds to bone matrix glycoconjugates and proteoglycans, was used in pit formation assays to assess the act...

journal_title：Calcified tissue international

authors： Selander K,Lehenkari P,Väänänen HK

更新日期：1994-11-01 00:00:00

abstract：:To define the quantitative aspects of ossification of human fetal spine, we performed a high resolution densitometric study by lateral and postero-anterior scanning of five fetal spines (18-36 weeks of conceptual age) and one spine of a 4-month-old infant. The data were plotted against developmental age for each spine...

journal_title：Calcified tissue international

authors： Panattoni GL,Sciolla A,Isaia GC

更新日期：1995-07-01 00:00:00

abstract：:Enamel of intact human teeth laser irradiated in vitro under certain conditions is known to have less subsurface demineralization than unirradiated enamel on exposure to acid; consequently, the potential use of laser irradiance to reduce caries is apparent. The laser-induced physical and/or chemical changes that cause...

journal_title：Calcified tissue international

authors： Fowler BO,Kuroda S

更新日期：1986-04-01 00:00:00

abstract：:The goal of this study was to find out if bone can recover after long-term administration of bisphosphonate. Disodium pamidronate (APD) was given orally by gavage to mature beagle dogs at doses of 0, 2.5, 12.5, and 25 mg/kg/day for 1 year (0.1% concentration) and the animals were allowed to recover for another year. A...

journal_title：Calcified tissue international

authors： Grynpas MD,Kasra M,Dumitriu M,Nespeca R,Very JM,Mertz BP

更新日期：1994-10-01 00:00:00

abstract：:Age-related loss of skeletal muscle is associated with increased risk of functional limitation and cardiovascular (CV) mortality. In the elderly abdominal aortic calcification (AAC) can increase CV risk by altering aortic properties which may raise blood pressure and increase cardiac workload. This study investigated ...

journal_title：Calcified tissue international

authors： Rodríguez AJ,Scott D,Khan B,Khan N,Hodge A,English DR,Giles GG,Ebeling PR

更新日期：2016-10-01 00:00:00

abstract：:We analyzed the bone microarchitecture of the subcapital and basicervical subregions of the femoral neck in men, to determine whether microarchitectural differences of cortical or trabecular bone can explain differential frequency of subcapital vs. basicervical fractures, especially in aged persons. The study sample e...

journal_title：Calcified tissue international

authors： Cirovic A,Cirovic A,Djonic D,Zivkovic V,Nikolic S,Djuric M,Milovanovic P

更新日期：2020-09-01 00:00:00

abstract：:Macroporous biphasic calcium phosphate (MBCP) blocks were implanted into rabbit trabecular bone and muscle, recovered 18 weeks later, and then observed and analyzed by transmission electron microscopy (TEM), electron diffraction, and electron microprobes. The results showed that (1) apatitic microcrystals appeared by ...

journal_title：Calcified tissue international

authors： Rohanizadeh R,Trécant-Viana M,Daculsi G

更新日期：1999-05-01 00:00:00

abstract：:To assess whether vertebral fractures are associated with osteopenia in chronic alcoholic patients, a transversal study was carried out in 76 chronic alcoholic males and 62 age-matched healthy males. Lumbar bone mineral density (BMD) by dual photon absorptiometry and spinal chest X-ray films were done in all patients....

journal_title：Calcified tissue international

authors： Peris P,Guañabens N,Parés A,Pons F,del Rio L,Monegal A,Surís X,Caballería J,Rodés J,Muñoz-Gómez J

更新日期：1995-08-01 00:00:00

abstract：:In general, physical exercise appears to have favorable effects on the skeleton. However, a few recent reports have described negative effects, including reduced bone density (BMD) and high bone turnover in runners. The aim of our study was to compare endurance runners to controls with respect to BMD at different site...

journal_title：Calcified tissue international

authors： Brahm H,Ström H,Piehl-Aulin K,Mallmin H,Ljunghall S

更新日期：1997-12-01 00:00:00

abstract：:The bone anabolic effect of parathyroid hormone (PTH) therapy is blunted when used in patients who were previously on bisphosphonate treatment. Osteocytes may play a role in the bisphosphonate silencing effect on PTH therapy since bisphosphonates have been shown to reach the lacunocanalicular system. In vivo osteocyte...

journal_title：Calcified tissue international

authors： Kuroshima S,Elliott KW,Yamashita J

更新日期：2013-06-01 00:00:00

abstract：:Long chain polyunsaturated fatty acids (LCPUFAs) are involved in the regulation of bone metabolism. Increased dietary consumption of n-3, and possibly some n-6, LCPUFAs may limit postmenopausal bone loss. The aim of this study was to determine the effects on bone of specific fatty acids within the n-3 and n-6 LCPUFA f...

journal_title：Calcified tissue international

authors： Poulsen RC,Firth EC,Rogers CW,Moughan PJ,Kruger MC

更新日期：2007-12-01 00:00:00

abstract：:Bone loss occurs as early as the third decade and its cumulative effect throughout adulthood may impact risk for osteoporosis in later life, however, the genes and environmental factors influencing early bone loss are largely unknown. We investigated the role of genes in the change in bone mineral density (BMD) in par...

journal_title：Calcified tissue international

authors： Shaffer JR,Kammerer CM,Bruder JM,Cole SA,Dyer TD,Almasy L,Maccluer JW,Blangero J,Bauer RL,Mitchell BD

更新日期：2009-02-01 00:00:00

abstract：:Osteonectin, gamma-carboxyglutamic acid-containing (Gla) protein, and dentin phosphoprotein were covalently attached to sepharose beads and inoculated in solutions at two different degrees of supersaturation with respect to both octacalcium phosphate (OCP) and hydroxyapatite. In both solutions, the inhibitory activity...

journal_title：Calcified tissue international

authors： Doi Y,Horiguchi T,Kim SH,Moriwaki Y,Wakamatsu N,Adachi M,Shigeta H,Sasaki S,Shimokawa H

更新日期：1993-02-01 00:00:00

abstract：:Results of previous studies suggest that children and adolescents with osteogenesis imperfecta (OI) type IV have muscle force deficits. However, muscle function remains to be objectively quantified in this population. This study aimed to assess upper and lower extremity muscle function in patients with OI type IV. It ...

journal_title：Calcified tissue international

authors： Veilleux LN,Darsaklis VB,Montpetit K,Glorieux FH,Rauch F

更新日期：2017-10-01 00:00:00

abstract：:The Sarcopenia and Quality of Life questionnaire (SarQol®) is a self-administered multidimensional sarcopenia-specific tool designed for community-dwelling subjects aged 65 years and older. The purpose of the present study was to evaluate the psychometric properties of the Spanish version of the SarQoL®. A total of 25...

journal_title：Calcified tissue international

authors： Fábrega-Cuadros R,Martínez-Amat A,Cruz-Díaz D,Aibar-Almazán A,Hita-Contreras F

更新日期：2020-03-01 00:00:00

abstract：:Vitamin D supplements are often recommended to restore sufficiency, although the adherence to treatment is low. This study assessed vitamin D status at different time intervals following the cessation of treatment. The database of Clalit-Health-Services (CHS), a not-for-profit HMO covering more than half of the Israel...

journal_title：Calcified tissue international

authors： Saliba W,Barnett O,Rennert HS,Lavi I,Rennert G

更新日期：2011-11-01 00:00:00

abstract：:Parathyroid hormone (PTH), hPTH-(1-84), and its hPTH-(1-34), hPTH-(1-31)NH2, and hPTH-(1-30)NH2 fragments reduced the tail artery pressure in anesthetized female Sprague-Dawley rats by 42.4-67.1% within about 1 minute after injection into a femoral vein, but reduced the pressure by only 8.5-36.2% 2-19 minutes after su...

journal_title：Calcified tissue international

authors： Whitfield JF,Morley P,Ross V,Preston E,Soska M,Barbier JR,Isaacs RJ,Maclean S,Ohannessian-Barry L,Willick GE

更新日期：1997-03-01 00:00:00

abstract：:KH1060 is a new 20-epi-vitamin D3 analog, which has exerted a considerable immunosuppressive potency in vitro. We have tested in vivo the effect of KH1060 on the suppression of renal allograft rejection in the rat. Allogenic kidney transplantation from DA donor rats to Lewis recipient rats treated intraperitoneally wi...

journal_title：Calcified tissue international

authors： Lewin E,Olgaard K

更新日期：1994-02-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAID) have been recommended to prevent of heterotopic ossification (HO) after total hip arthroplasty (THA), but debates are still ongoing. The present Bayesian network meta-analysis of randomized clinical trials (RCTs) compared all available pathways of NSAID treatment as prophy...

journal_title：Calcified tissue international

authors： Migliorini F,Trivellas A,Eschweiler J,Driessen A,Tingart M,Maffulli N

更新日期：2021-02-01 00:00:00

abstract：:Irrespective of the method used for noninvasive bone mass determination, data comparison between different centers is a major problem as significant interunit variation may occur. We, therefore, have employed mobile densitometry units to reduce interunit variability in two large epidemiologic studies in Germany. Two c...

journal_title：Calcified tissue international

authors： Wapniarz M,Lehmann R,Randerath O,Baedeker S,John W,Klein K,Allolio B

更新日期：1994-03-01 00:00:00

abstract：:Formalin fixation of hard tissues alters the levels of some, but not all, of the parameters routinely measured by bone researchers. Although mineral parameters (ash weight, particle size (beta 1/2 002) and Ca/PO4 ratio) and lipid parameters (total lipid content and composition, extractability, and Ca-acidic phospholip...

journal_title：Calcified tissue international

authors： Boskey AL,Cohen ML,Bullough PG

更新日期：1982-07-01 00:00:00

abstract：:A positional cloning effort in French Canadian families with Paget's disease of bone (PDB) resulted in the identification of a mutation in the sequestosome1 (SQSTM1) gene in a subset of both familial and sporadic PDB cases. This was confirmed in samples of mainly United Kingdom (UK) origin. In this study, we performed...

journal_title：Calcified tissue international

authors： Beyens G,Van Hul E,Van Driessche K,Fransen E,Devogelaer JP,Vanhoenacker F,Van Offel J,Verbruggen L,De Clerck L,Westhovens R,Van Hul W

更新日期：2004-08-01 00:00:00

abstract：:The effects of the trace metals zinc (Zn), manganese (Mn), and cadmium (Cd) on the metabolism of growth plate chondrocytes was examined using a mineralizing culture system. Supplementation of serum-free primary cultures of growth plate chondrocytes with 10-100 mu m Zn resulted in an increase in cell protein and greatl...

journal_title：Calcified tissue international

authors： Litchfield TM,Ishikawa Y,Wu LN,Wuthier RE,Sauer GR

更新日期：1998-04-01 00:00:00

abstract：:To determine the relationships among nutrients intake, bone mass, and bone turnover in women we have investigated these issues in a population-based, cross-sectional, observational study in one county in central Sweden. A total of 175 women aged 28-74 at entry to the study were included. Dietary assessment was made by...

journal_title：Calcified tissue international

authors： Michaëlsson K,Holmberg L,Mallmin H,Wolk A,Bergström R,Ljunghall S

更新日期：1995-08-01 00:00:00

abstract：:Biochemical markers applicable to the ovariectomized rat model can provide important tools for studying the bone remodeling process in this animal model of postmenopausal osteoporosis. We describe the development and application of two biochemical markers, a C-telopeptide (of type-I collagen) enzyme-linked immunosorbe...

journal_title：Calcified tissue international

authors： Srivastava AK,Bhattacharyya S,Castillo G,Wergedal J,Mohan S,Baylink DJ

更新日期：2000-06-01 00:00:00

abstract：:In order to investigate the pathogenesis of ossification of the posterior longitudinal ligament (OPLL) of the spine, we examined the distribution of insulin-like growth factor I (IGF-I) in the posterior longitudinal ligaments of OPLL patients, and analyzed the effects of IGF-I on the cultured spinal ligament cells. Fo...

journal_title：Calcified tissue international

authors： Goto K,Yamazaki M,Tagawa M,Goto S,Kon T,Moriya H,Fujimura S

更新日期：1998-02-01 00:00:00

abstract：:The purpose of this study was to determine whether human parathyroid hormone (h-PTH) enhances trabecular bone mass and connectivities that were reduced by streptozotocin (STZ)-induced diabetes in rats. Seven-month-old female Wistar rats were injected with STZ or its vehicle intraperitoneally. All vehicle-injected norm...

journal_title：Calcified tissue international

authors： Tsuchida T,Sato K,Miyakoshi N,Abe T,Kudo T,Tamura Y,Kasukawa Y,Suzuki K

更新日期：2000-03-01 00:00:00

abstract：:Methotrexate (MTX) is one of the most commonly prescribed drugs for autoimmune rheumatic diseases. As there is no consensus on its negative effects on bone, the purpose of this investigation was to determine the clinical spectrum of patients with stress fractures due to long-term MTX treatment (i.e., MTX osteopathy). ...

journal_title：Calcified tissue international

authors： Rolvien T,Jandl NM,Stürznickel J,Beil FT,Kötter I,Oheim R,Lohse AW,Barvencik F,Amling M

更新日期：2021-02-01 00:00:00

abstract：:We studied the relationship between serum calcium (Ca) and parathyroid hormone (PTH) in patients with idiopathic hypoparathyroidism (IHP) to investigate the diversity of the degree of parathyroid insufficiency and a regulation of PTH secretion by Ca in IHP. Serum intact PTH concentrations ranged from < 1.0 to 10.3 pg/...

journal_title：Calcified tissue international

authors： Mizunashi K,Furukawa Y,Abe K,Yoshinaga K

更新日期：1993-12-01 00:00:00

abstract：:Bone involvement, mainly osteoporosis but also osteosclerosis, is frequent in patients with indolent systemic mastocytosis (ISM). The recent characterization of the canonical Wnt/β-catenin pathway in the regulation of bone remodeling provided important insights for our understanding of the pathophysiology of a number ...

journal_title：Calcified tissue international

authors： Rossini M,Viapiana O,Zanotti R,Tripi G,Perbellini O,Idolazzi L,Bonifacio M,Adami S,Gatti D

更新日期：2015-05-01 00:00:00