Histomorphometric evaluation of the recovering effect of human parathyroid hormone (1-34) on bone structure and turnover in streptozotocin-induced diabetic rats.

abstract：:The small proteoglycan decorin had been localized previously at the d-band in the gap zone of collagen fibrils in nonmineralizing tissues. In bone matrix this zone is proteoglycan free and is at least in some species the place where mineralization along collagen fibrils starts. To study the metabolism of the small pro...

journal_title：Calcified tissue international

authors： Blumberg P,Brenner R,Budny S,Kresse H

更新日期：1997-06-01 00:00:00

abstract：:Aluminum ions (Al) and chromium (III) ions (Cr), as they exist in aqueous solution at neutral pH, adsorb onto calcium hydroxyapatite crystals (HAP) and severely inhibit their dissolution process, when present in concentrations less than 1 microM. Iron (III) ions (Fe), at concentrations up to 10 microM, have no effect ...

journal_title：Calcified tissue international

authors： Christoffersen MR,Thyregod HC,Christoffersen J

更新日期：1987-07-01 00:00:00

abstract：:Dickkopf-1 (DKK1) and sclerostin are antagonists of the Wnt/β-catenin pathway and decreased expression of either results in increased bone formation and mass. As both affect the same signaling pathway, we aimed to elucidate the redundancy and/or compensation of sclerostin and DKK1. Weekly sclerostin antibody (Scl-Ab) ...

journal_title：Calcified tissue international

authors： Morse A,Cheng TL,Schindeler A,McDonald MM,Mohanty ST,Kneissel M,Kramer I,Little DG

更新日期：2018-09-01 00:00:00

abstract：:The aim of this study was to evaluate bone resorption (BR) in rats by two methods: chronic 3H-tetracycline labeling (3HTC) and pyridinium crosslink excretion (PYDX), and compare the sensitivity of these markers in two age groups. Female Sprague-Dawley rats at 12-29 weeks of age ("mature", n = 12) and at 40-57 weeks of...

journal_title：Calcified tissue international

authors： Talbott SM,Chowdhury H,Shapses SA

更新日期：1999-04-01 00:00:00

abstract：:Total fat mass plays a significant role in determining bone mass, but the specific role of central adiposity independent of total fat mass has not been widely studied. Prepubertal (Tanner 1) children (n = 181; 65 boys, 116 girls, 7.8 +/- 1.5 years), including 99 Caucasians and 82 African Americans from Birmingham, Ala...

journal_title：Calcified tissue international

authors： Afghani A,Goran MI

更新日期：2006-12-01 00:00:00

abstract：:Transcriptional regulation of the postnatal skeleton is incompletely understood. Here, we determined the consequence of loss of early growth response gene 1 (EGR-1) on bone properties. Analyses were performed on both the microscopic and molecular levels utilizing micro-computed tomography (micro-CT) and Fourier transf...

journal_title：Calcified tissue international

authors： Reumann MK,Strachna O,Lukashova L,Verdelis K,Donnelly E,Boskey AL,Mayer-Kuckuk P

更新日期：2011-07-01 00:00:00

abstract：:A 56 year-old man with a 2-year history of transitional-cell carcinoma of the urinary bladder presented with back pain and diffuse radiological osteosclerosis. Laboratory studies revealed borderline-low ionized serum calcium, and markedly elevated serum alkaline phosphatase (ALP) activity and serum osteocalcin. Serum ...

journal_title：Calcified tissue international

authors： Liel Y,Maor E,Ariad S,Lowenthal MN

更新日期：1998-12-01 00:00:00

abstract：:Radiation therapy (RT) is an established treatment modality for malignant neoplasms. RT induces tissue damage that may lead to osteoradionecrosis in more severe cases. Suitable animal models to study RT-induced changes in membranous craniofacial bone are currently not available. The aim of this study was therefore to ...

journal_title：Calcified tissue international

authors： Desmons S,Heger M,Delfosse C,Falgayrac G,Sarrazin T,Delattre C,Catros S,Mordon S,Penel G

更新日期：2009-05-01 00:00:00

abstract：:Osteocalcin, the gamma-carboxyglutamic acid-containing protein, which is the most abundant noncollagenous protein of bone and dentin, is considered to play roles in bone formation and remodeling. It is unclear how the gamma-carboxyglutamic acid side-chains in osteocalcin coordinate to Ca2+, since the X-ray structure o...

journal_title：Calcified tissue international

authors： Mizuguchi M,Fujisawa R,Nara M,Nitta K,Kawano K

更新日期：2001-12-01 00:00:00

abstract：:Bone collagen undergoes a series of enzymatic and nonenzymatic posttranslational modifications with maturation. The aim of this study was to analyze the collagenolytic efficiency of cathepsin K in relation to the extent of bone collagen age. Bone collagen posttranslational maturation was induced in vitro by preincubat...

journal_title：Calcified tissue international

authors： Borel O,Gineyts E,Bertholon C,Garnero P

更新日期：2012-07-01 00:00:00

abstract：:Regular tennis play is associated with impressive asymmetries in bone strength in favor of the racquet arm, particularly in the humerus. However, the relative effects of service and ground strokes are not known. Serendipitously, we encountered a 46-year-old regular tennis player who has played service and ground strok...

journal_title：Calcified tissue international

authors： Ireland A,Degens H,Maffulli N,Rittweger J

更新日期：2015-08-01 00:00:00

abstract：:Periodic fringes corresponding to six different lattice planes have been observed in apatite crystals of human normal alveolar bone by transmission electron microscopy. Three of these sets of fringes have spacings less than 3.5 A corresponding to the Scherzer resolution of the microscope used. The (0002) lattice plane...

journal_title：Calcified tissue international

authors： Cuisinier F,Bres EF,Hemmerle J,Voegel JC,Frank RM

更新日期：1987-06-01 00:00:00

abstract：:There is increasing evidence that 1,25 dihydroxyvitamin D3 acts directly to differentiate and activate cells of mononuclear phagocyte lineage (MNP). However, it seems possible that in bone marrow this hormone may modulate the differentiation of MNP via the factor elaborated by the stromal cells or the macrophages. We ...

journal_title：Calcified tissue international

authors： Nakamura T,Araki K,Kanda S,Kurisu K

更新日期：1986-01-01 00:00:00

abstract：:The peptide hormone calcitonin is a potent inhibitor of osteoclastic resorption, but it is unstable and poorly absorbed following oral administration. Conjugates of salmon calcitonin covalently linked to low-molecular-weight amphiphilic polymers show improved stability and absorption. The purpose of this study was to ...

journal_title：Calcified tissue international

authors： Komarova SV,Shum JB,Paige LA,Sims SM,Dixon SJ

更新日期：2003-09-01 00:00:00

abstract：:Studies suggest that long-term use of proton pump inhibitors (PPIs) may be associated with an increased risk of fracture. However, the role of medication adherence in this association is not fully understood. A retrospective cohort study was conducted to examine the relationship between PPI use/adherence and fracture ...

journal_title：Calcified tissue international

authors： Ding J,Heller DA,Ahern FM,Brown TV

更新日期：2014-06-01 00:00:00

abstract：:The type IA osteogenesis imperfecta (OI) phenotype is characterized by multiple fractures, blue sclerae, and minimal skeletal deformity without dentinogenesis imperfecta. The object of this study was to determine the effect of treatment with intravenous pamidronate (30 mg) every 3 months on bone density and bone histo...

journal_title：Calcified tissue international

authors： Shapiro JR,McCarthy EF,Rossiter K,Ernest K,Gelman R,Fedarko N,Santiago HT,Bober M

更新日期：2003-02-01 00:00:00

abstract：:The phorbol ester 12-O-tetradecanoyl-13-acetate (TPA) blocked the growth of, and induced the appearance of processes in the human osteosarcoma cell line U-2 OS. The phorbol ester decreased the intracellular level of alkaline phosphatase (APase) activity (as measured per mg cell protein) and caused a marked increase in...

journal_title：Calcified tissue international

authors： Ringbom-Anderson T,Akerman KE

更新日期：1992-06-01 00:00:00

abstract：:The objective of this study was to compare the bone mineral density (BMD) of men with Down syndrome (DS) to otherwise mentally retarded (MR) men and to investigate whether leg muscle strength of these patients is related to BMD. Two groups with MR (with and without DS) participated in the study, having met the followi...

journal_title：Calcified tissue international

authors： Angelopoulou N,Matziari C,Tsimaras V,Sakadamis A,Souftas V,Mandroukas K

更新日期：2000-03-01 00:00:00

abstract：:This study revealed the distinguished changes of preferential orientation of collagen and apatite and Young's modulus in two different types of osteoporotic bones compared with the normal bone. Little is known about the bone material properties of osteoporotic bones; therefore, we aimed to assess material properties i...

journal_title：Calcified tissue international

authors： Ozasa R,Ishimoto T,Miyabe S,Hashimoto J,Hirao M,Yoshikawa H,Nakano T

更新日期：2019-04-01 00:00:00

abstract：:Bone mineral content (BMC) and bone mineral density (BMD) are common but imperfect surrogate measures of bone strength. The mechanical response tissue analyzer is a device that measures long bone bending stiffness (EI), which strongly predicts bone breaking strength. We hypothesized that isokinetic resistance training...

journal_title：Calcified tissue international

authors： Miller LE,Nickols-Richardson SM,Wootten DF,Ramp WK,Steele CR,Cotton JR,Carneal JP,Herbert WG

更新日期：2009-06-01 00:00:00

abstract：:The purpose of this study was to determine the efficacy of using bone mineral measurements of the calcaneus to evaluate osteoporosis. Dual energy X-ray absorptiometry (DXA) of the calcaneus was compared with posteroanterior lumbar absorptiometry (DXA) and vertebral quantitative computed tomography (QCT) measurements i...

journal_title：Calcified tissue international

authors： Laval-Jeantet AM,Bergot C,Williams M,Davidson K,Laval-Jeantet M

更新日期：1995-01-01 00:00:00

abstract：:Octacalcium phosphate (Ca8H2(PO4)6 . 5H2O) is considered to be precursor in the formation of apatite in bones and teeth; a crucial step for incorporation of impurities appears to occur during its hydrolysis. The present study examines the role that octacalcium phosphate plays in the process of incorporation of carbona...

journal_title：Calcified tissue international

authors： Chickerur NS,Tung MS,Brown WE

更新日期：1980-01-01 00:00:00

abstract：:We separated osteoclasts from bone and observed the effect of several known and potential mediators of the control of bone resorption on their cytoplasmic motility. We already found that calcitonin (CT), a hormone that inhibits bone resorption, regularly causes complete inhibition of cytoplasmic motility, specific for...

journal_title：Calcified tissue international

authors： Chambers TJ,Dunn CJ

更新日期：1983-07-01 00:00:00

abstract：:Enamel of intact human teeth laser irradiated in vitro under certain conditions is known to have less subsurface demineralization than unirradiated enamel on exposure to acid; consequently, the potential use of laser irradiance to reduce caries is apparent. The laser-induced physical and/or chemical changes that cause...

journal_title：Calcified tissue international

authors： Fowler BO,Kuroda S

更新日期：1986-04-01 00:00:00

abstract：:An organ culture system has been developed whereby mechanical stress can be applied to cranial sutures under controlled experimental conditions. The application of a continuous tensile mechanical stress (30 g) to cranial sutures from newborn rabbits (1--2 days) was accompanied by a significant increase in the incorpor...

journal_title：Calcified tissue international

authors： Meikle MC,Reynolds JJ,Sellers A,Dingle JT

更新日期：1979-10-31 00:00:00

abstract：:Vitamin D supplementation is recommended for women with osteoporosis. In the FOCUS-D trial comparing the combination tablet alendronate plus vitamin D3 5,600 IU (ALN/D) with standard care (SC) prescribed by patients' personal physicians, ALN/D was more effective in improving serum 25(OH)D and bone turnover markers by ...

journal_title：Calcified tissue international

authors： Roux C,Binkley N,Boonen S,Kiel DP,Ralston SH,Reginster JY,Pong A,Rosenberg E,Santora A,FOCUS-D Investigators.

更新日期：2014-02-01 00:00:00

abstract：:To determine the relationships among nutrients intake, bone mass, and bone turnover in women we have investigated these issues in a population-based, cross-sectional, observational study in one county in central Sweden. A total of 175 women aged 28-74 at entry to the study were included. Dietary assessment was made by...

journal_title：Calcified tissue international

authors： Michaëlsson K,Holmberg L,Mallmin H,Wolk A,Bergström R,Ljunghall S

更新日期：1995-08-01 00:00:00

abstract：:The purpose of this research was to address the following question: How is the solubility of fluoride-pretreated carbonated apatite (CAP) in aqueous acidic media related to the equilibrium solution fluoride and/or the CAP adsorbed fluoride levels? A CAP sample prepared by a precipitation method at 70 degrees C contain...

journal_title：Calcified tissue international

authors： Barry AB,Zhuang H,Baig AA,Higuchi WI

更新日期：2003-03-01 00:00:00

abstract：:This study aimed to investigate the effects of recombinant human bone morphogenetic protein (rhBMP-7) on human cancellous bone grafts (BGs) while differentiating between anabolic and catabolic events. Human BGs alone or supplemented with rhBMP-7 were harvested 14 weeks after subcutaneous implantation into NOD/Scid mic...

journal_title：Calcified tissue international

authors： Lahr CA,Wagner F,Shafiee A,Rudert M,Hutmacher DW,Holzapfel BM

更新日期：2019-09-01 00:00:00

abstract：:Molybdenum (Mo), at high concentrations, induces changes in the epiphyseal growth plate through its effects on copper (Cu) metabolism but it is unclear whether or not Mo can induce changes independent of its effects on copper status. To this end, the effect of Mo on longitudinal bone growth was examined in rats. Dieta...

journal_title：Calcified tissue international

authors： Parry NM,Phillippo M,Reid MD,McGaw BA,Flint DJ,Loveridge N

更新日期：1993-09-01 00:00:00