The relationship between proton pump inhibitor adherence and fracture risk in the elderly.

abstract：:Total fat mass plays a significant role in determining bone mass, but the specific role of central adiposity independent of total fat mass has not been widely studied. Prepubertal (Tanner 1) children (n = 181; 65 boys, 116 girls, 7.8 +/- 1.5 years), including 99 Caucasians and 82 African Americans from Birmingham, Ala...

journal_title：Calcified tissue international

authors： Afghani A,Goran MI

更新日期：2006-12-01 00:00:00

abstract：:Arterial calcification leading to increased arterial stiffness, a powerful risk factor for cardiovascular disease, may underlie the association of osteoporosis with cardiovascular disease in postmenopausal women. Osteoprotegerin (OPG), an indirect inhibitor of osteoclastogenesis, may be involved in arterial calcificat...

journal_title：Calcified tissue international

authors： Frost ML,Grella R,Millasseau SC,Jiang BY,Hampson G,Fogelman I,Chowienczyk PJ

更新日期：2008-08-01 00:00:00

abstract：:Bone is a dynamic tissue that is able to sense and adapt to mechanical stimuli by modulating its mass, geometry, and structure. Bone marrow stromal cells (BMSCs) are known to play an integral part in bone formation by providing an osteoprogenitor cell source capable of differentiating into mature osteoblasts in respon...

journal_title：Calcified tissue international

authors： Mauney JR,Sjostorm S,Blumberg J,Horan R,O'Leary JP,Vunjak-Novakovic G,Volloch V,Kaplan DL

更新日期：2004-05-01 00:00:00

abstract：:Osteoporosis is a common age-related disease with a strong genetic influence. COLIA1 is one of the most extensively studied candidate genes and has consistently been associated with BMD and fracture. We examined the effects of the polymorphisms -1997G>T, -1663indelT, and +1245G>T and their haplotypes on vertebral frac...

journal_title：Calcified tissue international

authors： Husted LB,Harsløf T,Gonzalez-Bofill N,Schmitz A,Carstens M,Stenkjaer L,Langdahl BL

更新日期：2009-02-01 00:00:00

abstract：:To assess whether vertebral fractures are associated with osteopenia in chronic alcoholic patients, a transversal study was carried out in 76 chronic alcoholic males and 62 age-matched healthy males. Lumbar bone mineral density (BMD) by dual photon absorptiometry and spinal chest X-ray films were done in all patients....

journal_title：Calcified tissue international

authors： Peris P,Guañabens N,Parés A,Pons F,del Rio L,Monegal A,Surís X,Caballería J,Rodés J,Muñoz-Gómez J

更新日期：1995-08-01 00:00:00

abstract：:The aim of this study was to follow the changes in bone mineral density (BMD) and biochemical markers of bone turnover in 10 children (7.5-17.5 years of age) with severe juvenile idiopathic arthritis (JIA), during a 3-year therapy with salmon calcitonin (100 IU/day 2 months on and 2 off for a year and 200 IU/day for 2...

journal_title：Calcified tissue international

authors： Siamopoulou A,Challa A,Kapoglou P,Cholevas V,Mavridis AK,Lapatsanis PD

更新日期：2001-07-01 00:00:00

abstract：:Alkaptonuria (AKU) is characterised by increased circulating homogentisic acid and deposition of ochronotic pigment in collagen-rich connective tissues (ochronosis), stiffening the tissue. This process over many years leads to a painful and severe osteoarthropathy, particularly affecting the cartilage of the spine and...

journal_title：Calcified tissue international

authors： Hughes JH,Keenan CM,Sutherland H,Edwards HR,Wilson PJM,Ranganath LR,Jarvis JC,Bou-Gharios G,Gallagher JA

更新日期：2021-02-01 00:00:00

abstract：:The metacarpal bone mineral density (BMD) and metacarpal index (MCI) of the second metacarpal bone were measured by computed X-ray densitometry (CXD) (Teijin Ltd., Tokyo), which we have established with the development of microdensitometry of radiographs. In this study, we evaluated the basic attributes of this CXD me...

journal_title：Calcified tissue international

authors： Matsumoto C,Kushida K,Yamazaki K,Imose K,Inoue T

更新日期：1994-11-01 00:00:00

abstract：:We have compared two components of bacterial cell walls, muramyl dipeptide (MDP) and lipopolysaccharide (LPS), for their effects on bone resorption as measured by the release of previously incorporated 45Ca. MDP is the smallest active component of peptidoglycan, whereas LPS is the active component of endotoxin. Fetal ...

journal_title：Calcified tissue international

authors： Raisz LG,Alander C,Eilon G,Whitehead SP,Nuki K

更新日期：1982-07-01 00:00:00

abstract：:We have previously noted that a relatively large load (150 N) is required to induce a strain on the cortex of rat vertebrae similar to that induced on weight-bearing bones by normal mechanical usage. It seems unlikely that the musculature of the tail normally imposes loads of this magnitude, and this suggests that the...

journal_title：Calcified tissue international

authors： Chow JW,Jagger CJ,Chambers TJ

更新日期：1996-08-01 00:00:00

abstract：:SUMMARY. The high variation often observed in the ex vivo fibroblastic-colony forming unit (CFU-f) assay is likely to be due to both biological and experimental variation. To determine whether we could improve experimental methods we developed an alternative method of bone marrow cell (BMC) isolation employing a centr...

journal_title：Calcified tissue international

authors： Dobson KR,Reading L,Haberey M,Marine X,Scutt A

更新日期：1999-11-01 00:00:00

abstract：:A 69-year-old man became hypocalcemic under medical observation. The hypocalcemia occurred in the presence of circulating immunoreactive parathyroid hormone (PTH). Common causes of secondary hyperparathyroidism were excluded, as was PTH resistance using PTH infusions. The immunoreactive PTH was examined in detail. PTH...

journal_title：Calcified tissue international

authors： McElduff A,Lackmann M,Wilkinson M

更新日期：1992-08-01 00:00:00

abstract：:Osteocalcin, the gamma-carboxyglutamic acid-containing protein, which is the most abundant noncollagenous protein of bone and dentin, is considered to play roles in bone formation and remodeling. It is unclear how the gamma-carboxyglutamic acid side-chains in osteocalcin coordinate to Ca2+, since the X-ray structure o...

journal_title：Calcified tissue international

authors： Mizuguchi M,Fujisawa R,Nara M,Nitta K,Kawano K

更新日期：2001-12-01 00:00:00

abstract：:Anemia is commonly associated with osteoporosis and sarcopenia in older persons. However, there is a common subset of patients identified as osteosarcopenic at a higher risk of adverse outcomes. Whether these patients are also at a higher risk of anemia remains unknown. In this study, we aimed to compare hemoglobin (H...

journal_title：Calcified tissue international

authors： Bani Hassan E,Vogrin S,Hernandez Viña I,Boersma D,Suriyaarachchi P,Duque G

更新日期：2020-08-01 00:00:00

abstract：:Inorganic phosphate (P(i)) can regulate the level of skeletal alkaline phosphatase (ALP) activity in human osteoblast-like cells, but not by means of changes in transcription or release from the cell surface. The current studies were intended to determine whether (1) P(i) affected the inactivation of ALP activity in h...

journal_title：Calcified tissue international

authors： Farley JR

更新日期：1995-11-01 00:00:00

abstract：:Hepatitis C treatment with interferon alpha-2b (IFN-alpha) and ribavirin has been related to decreased bone mineral density. The aim of this study was to investigate the in vitro effects of different concentrations of ribavirin and IFN-alpha on osteoblast-like cells. Human osteoblast-like cells obtained by the outgrow...

journal_title：Calcified tissue international

authors： Moreira RO,Balduíno A,Martins HS,Reis JS,Duarte ME,Farias ML,Borojevic R

更新日期：2004-08-01 00:00:00

abstract：:The method of heat-denaturation and trypsin digestion was used to dissect bone biochemically into mineral-protected and mineral-unprotected pools of collagenous matrix. It was found that varying the particle size of the bone powder had a profound effect on the results. Using mature bovine cortical bone, the observed p...

journal_title：Calcified tissue international

authors： Wu JJ,Eyre DR

更新日期：1988-04-01 00:00:00

abstract：:Proton pump inhibitors are taken by millions of patients for prevention and treatment of gastroesophageal diseases. Case-control studies have suggested that use of omeprazole is associated with an increased risk of hip fractures. The aim of this prospective study was to assess the risk of vertebral fractures in postme...

journal_title：Calcified tissue international

authors： Roux C,Briot K,Gossec L,Kolta S,Blenk T,Felsenberg D,Reid DM,Eastell R,Glüer CC

更新日期：2009-01-01 00:00:00

abstract：:Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats wer...

journal_title：Calcified tissue international

authors： Brun LR,Brance ML,Lombarte M,Maher MC,Di Loreto VE,Rigalli A

更新日期：2015-11-01 00:00:00

abstract：:We investigated the ultrastructural distribution and histochemical properties of sulfated glycoconjugates, which could be preserved by glutaraldehyde fixation, in secretory ameloblasts and developing enamel matrix, by use of the high iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining and enzymatic...

journal_title：Calcified tissue international

authors： Kogaya Y,Furuhashi K

更新日期：1988-11-01 00:00:00

abstract：:KH1060 is a new 20-epi-vitamin D3 analog, which has exerted a considerable immunosuppressive potency in vitro. We have tested in vivo the effect of KH1060 on the suppression of renal allograft rejection in the rat. Allogenic kidney transplantation from DA donor rats to Lewis recipient rats treated intraperitoneally wi...

journal_title：Calcified tissue international

authors： Lewin E,Olgaard K

更新日期：1994-02-01 00:00:00

abstract：:To study the risk of fractures associated with anxiolytics, sedatives, and hypnotics, we conducted a case-control study. Cases were all subjects with any fracture during the year 2000 (n = 124,655). For each case, three controls (n = 373,962) matched on age and gender were randomly drawn from the background population...

journal_title：Calcified tissue international

authors： Vestergaard P,Rejnmark L,Mosekilde L

更新日期：2008-01-01 00:00:00

abstract：:The Sarcopenia and Quality of Life questionnaire (SarQol®) is a self-administered multidimensional sarcopenia-specific tool designed for community-dwelling subjects aged 65 years and older. The purpose of the present study was to evaluate the psychometric properties of the Spanish version of the SarQoL®. A total of 25...

journal_title：Calcified tissue international

authors： Fábrega-Cuadros R,Martínez-Amat A,Cruz-Díaz D,Aibar-Almazán A,Hita-Contreras F

更新日期：2020-03-01 00:00:00

abstract：:Seventy-two postmenopausal osteoporotic women having more than one nontraumatic vertebral crush fracture were studied. Thirty-six of them, aged 68.8 +/- 1.2 years (18 +/- 4 YSM-years since menopause), were treated with 100 IU/day of salmon calcitonin i.m. plus 500 mg of elemental calcium for 10 days each month. The re...

journal_title：Calcified tissue international

authors： Rico H,Revilla M,Hernández ER,Villa LF,Alvarez de Buergo M

更新日期：1995-03-01 00:00:00

abstract：:The acute-phase response (APR) is a frequent occurrence after infusion of zoledronic acid and is caused by activation of γδ T cells. Vitamin D receptor is expressed in immune cells, and vitamin D has immunomodulatory properties. The aim of this prospective study was to test the effect of vitamin D (cholecalciferol) on...

journal_title：Calcified tissue international

authors： Catalano A,Morabito N,Atteritano M,Basile G,Cucinotta D,Lasco A

更新日期：2012-04-01 00:00:00

abstract：:Histomorphometric evaluation of bone formation in an intravital tetracycline-labeled skeleton of a suddenly deceased osteoporotic woman is presented. The 24 skeletal sites investigated displayed substantial regional variations which, for two out of four cortical bone dynamics and all trabecular bone dynamics, were sig...

journal_title：Calcified tissue international

authors： Pødenphant J,Engel U

更新日期：1987-04-01 00:00:00

abstract：:Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius...

journal_title：Calcified tissue international

authors： Nijs J,Van Essche E,De Munck M,Dequeker J

更新日期：2000-07-01 00:00:00

abstract：:Until 2006 the only mutations known to cause osteogenesis imperfecta (OI) were in the two genes coding for type I collagen chains. These dominant mutations affecting the expression or primary sequence of collagen α1(I) and α2(I) chains account for over 90% of OI cases. Since then a growing list of mutant genes causing...

journal_title：Calcified tissue international

authors： Eyre DR,Weis MA

更新日期：2013-10-01 00:00:00

abstract：:The purpose of this study was to (1) quantify the healing process of the human osteoporotic proximal humerus fracture (PHF) expressed in terms of callus formation over the fracture region using BMD scanning, and (2) quantify the impact of medical intervention with vitamin D3 and calcium on the healing process of the h...

journal_title：Calcified tissue international

authors： Doetsch AM,Faber J,Lynnerup N,Wätjen I,Bliddal H,Danneskiold-Samsøe B

更新日期：2004-09-01 00:00:00

abstract：:Tartrate resistant acid phosphatase (TRAP) has been proposed as a new biochemical marker for bone resorption. We have compared this new marker, TRAP, with the classical biochemical markers of bone remodelling, serum alkaline phosphatase (sAP), serum osteocalcin (sBGP), and with the urinary hydroxyproline/creatinine ra...

journal_title：Calcified tissue international

authors： Torres R,de la Piedra C,Rapado A

更新日期：1991-07-01 00:00:00