Abstract：
:Octacalcium phosphate (Ca8H2(PO4)6 . 5H2O) is considered to be precursor in the formation of apatite in bones and teeth; a crucial step for incorporation of impurities appears to occur during its hydrolysis. The present study examines the role that octacalcium phosphate plays in the process of incorporation of carbonate into apatite. Chemical, X-ray diffraction, and infrared techniques were used. When octacalcium phosphate is hydrolyzed in the presence of sodium and carbonate ions in aqueous media, approximately one sodium and one carbonate ion seem to substitute for a calcium and phosphate ion, respectively, in forming apatite, and the a axis is shortened. The infrared spectrum of the product indicates that the carbonate is in the type B site, which is presumed to be a phosphate site. This mechanism is of particular importance since the presence of carbonate in human enamel appears to be related to caries susceptibility. A structural mechanism for the incorporation of impurities during hydrolysis of octacalcium phosphate is presented.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Chickerur NS,Tung MS,Brown WEdoi
10.1007/BF02408521subject
Has Abstractpub_date
1980-01-01 00:00:00pages
55-62issue
1eissn
0171-967Xissn
1432-0827journal_volume
32pub_type
杂志文章abstract：:Data on the association between dietary vitamin K intake and fracture risk are limited among Chinese. This study examined such an association in community-dwelling elderly in Hong Kong. We present data from 2,944 subjects (1,605 men, 1,339 women) who participated in a prospective cohort study. Baseline dietary intakes...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-012-9586-5
更新日期：2012-05-01 00:00:00
abstract：:The purpose of the present study was to determine if the type of dietary fat can modify the fatty acid composition and arachidonic acid levels in the alveolar bone phospholipids. Three groups of rats were fed nutritionally adequate semipurified diets containing different lipids: 10% corn oil (control, group I, rich in...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF01351838
更新日期：1993-11-01 00:00:00
abstract：:Aging and sex hormones related changes lead to inflammatory and oxidant conditions, which are involved in the pathogenesis of osteoporosis. Recent studies have suggested that polyphenols may exert a protective effect in such conditions. We assessed the effect of phloridzin (Phlo), a flavonoid exclusively found in appl...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-005-0060-5
更新日期：2005-11-01 00:00:00
abstract：:Osteoarthritis and sarcopenia are the most frequently described musculoskeletal disorders in older persons but the intertwining of these conditions and of their functional and cellular causes is complex. This narrative review aims to identify the links between osteoarthritis and sarcopenia described 1-in clinical stud...
journal_title：Calcified tissue international
pub_type： 杂志文章,评审
doi：10.1007/s00223-020-00703-5
更新日期：2020-09-01 00:00:00
abstract：:Currently used diagnostic measures for sarcopenia are based on the evaluation of appendicular skeletal muscle mass (ASMM) divided by height-squared (ASMMI). This study aimed to investigate the associations between different operational definitions of appendicular muscle mass and BMD at different skeletal sites in agin...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-014-9902-3
更新日期：2014-10-01 00:00:00
abstract：:Ascorbic acid is a required cofactor in the hydroxylations of lysine and proline necessary for collagen formation; its role in bone cell differentiation and formation is less well characterized. This study examines the cross-sectional relation between dietary vitamin C intake and bone mineral density (BMD) in women fr...
journal_title：Calcified tissue international
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/s002239900512
更新日期：1998-09-01 00:00:00
abstract：:The primary aim of the project was to determine the combined effect of whole-body electromyostimulation (WB-EMS) and protein supplements on local and overall muscle/fat distribution in older man with sarcopenic obesity (SO). Community-dwelling (cdw) men ≥ 70 years with SO were randomly allocated to a WB-EMS and protei...
journal_title：Calcified tissue international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00223-018-0424-2
更新日期：2018-09-01 00:00:00
abstract：:The increased uptake of bone-seeking radionuclides following a fracture has been stated to be due to an increase in bone blood flow, resulting in an increase in capillary surface area available for exchange. This paper examines the relationship between the maximum instantaneous extraction of 99mTc-MDP and blood flow i...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02405085
更新日期：1983-07-01 00:00:00
abstract：:The aims of this study were to compare the response to therapy in disease activity in pagetic patients with and without skull involvement and the usefulness of bone markers in the evaluation of these patients. Forty patients with Paget's disease treated with tiludronate and 26 healthy controls were included. Serum tot...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-005-0247-9
更新日期：2006-07-01 00:00:00
abstract：:Radiation therapy (RT) is an established treatment modality for malignant neoplasms. RT induces tissue damage that may lead to osteoradionecrosis in more severe cases. Suitable animal models to study RT-induced changes in membranous craniofacial bone are currently not available. The aim of this study was therefore to ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-009-9217-y
更新日期：2009-05-01 00:00:00
abstract：:We carried out a clinical trial of 1 alpha-hydroxycholecalciferol [1 alpha(OH)D3] at a dose of 1.0 microgram a day on 7 patients with psoriasis vulgaris. These patients had been treated by topical applications of corticosteroids before this study without improvement, and during the clinical trial, treatment of topical...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02555172
更新日期：1986-12-01 00:00:00
abstract：:The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-012-9661-y
更新日期：2013-01-01 00:00:00
abstract：:Osteoclastic bone resorption can be induced within the auditory bulla of the Mongolian gerbil by minute increases in air pressure. The objective of this study was to determine the rate at which osteoclasts are induced in areas of resorption and to compare the rate of osteoblast recruitment. Stainless steel tubes were ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02556026
更新日期：1989-11-01 00:00:00
abstract：:Sclerostin and parathyroid hormones are strong negative and positive regulators of bone formation, respectively. The anabolic response induced by intermittent (iPTH) treatment is sclerostin status-dependent. However, the interaction between sclerostin and iPTH at the matrix level is unknown. The goal of the current st...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-015-0074-6
更新日期：2016-02-01 00:00:00
abstract：:Age-related loss of skeletal muscle is associated with increased risk of functional limitation and cardiovascular (CV) mortality. In the elderly abdominal aortic calcification (AAC) can increase CV risk by altering aortic properties which may raise blood pressure and increase cardiac workload. This study investigated ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-016-0157-z
更新日期：2016-10-01 00:00:00
abstract：:To characterize osteopenic changes in ovariectomized (OVX) rats as a function of time, female Sprague Dawley rats (240 g body weight, 90 days old) were subjected to bilateral ovariectomy or sham surgery and killed at various times from 14-180 days postovariectomy. The proximal tibial metaphysis was processed undecalci...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02571317
更新日期：1988-09-01 00:00:00
abstract：:MicroRNAs (miRNAs/miRs) are important biomarkers for the progression of intervertebral disc degeneration (IDD). We investigated the role of miR-30d in IDD progression through its interactions with forkhead box O3 (FOXO3) and C-X-C motif ligand 10 (CXCL10). We first measured the expression of miR-30d, FOXO3, and CXCL10...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-020-00760-w
更新日期：2021-02-01 00:00:00
abstract：:Serum immunoreactive osteocalcin (irOC) consists of two fractions that differ from each other by their affinity for hydroxyapatite. The high and low affinity fractions are referred to as irOCbound and irOCfree, respectively. To evaluate whether these fractions are determinants for different characteristics of bone or ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900543
更新日期：1998-11-01 00:00:00
abstract：:Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However, questions still persist concerning the effect of these drugs on bone properties such as ultrastructure and quality, particularly in the growing patient. To addres...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002230010045
更新日期：2001-08-01 00:00:00
abstract：:Cost-effective intervention thresholds (ITs) based on FRAX(®) were determined for Portugal. Assuming a willingness to pay (WTP) of €32,000 per quality-adjusted life years (QALYs), treatment with generic alendronate is cost effective for men and women aged 50 years or more, with 10-year probabilities for major osteopor...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-016-0132-8
更新日期：2016-08-01 00:00:00
abstract：:The accuracy of a radiographic absorptiometry (RA) technique called digital image processing (DIP), discriminative ability of RA for osteoporotic fracture, and the relationship between RA and dual X-ray absorptiometry (DXA) of the spine and forearm were evaluated. We measured 16 cadaver hands, 32 healthy non-black pre...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900400
更新日期：1998-02-01 00:00:00
abstract：:We examined differences in patients' survival after hip fracture (HF) and risk for subsequent HF among patients treated with oral and intravenous bisphosphonates (oBPs, iBPs), denosumab (DMAB), and patients without therapy. We used data from all patients in Austria aged ≥ 50 who sustained a HF between 2012 and 2017 an...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-019-00611-3
更新日期：2019-12-01 00:00:00
abstract：:Healing trabecular microfractures are a common feature in cancellous bone. These lesions, when observed in macerated cancellous bone slices, measure about 500 microns in diameter and surround fractures in trabeculae with microcallus. Whether microcallus is a structure acting primarily as a transient brace, preventing ...
journal_title：Calcified tissue international
pub_type： 杂志文章,评审
doi：10.1007/BF01673424
更新日期：1993-01-01 00:00:00
abstract：:Macroporous biphasic calcium phosphate (MBCP) blocks were implanted into rabbit trabecular bone and muscle, recovered 18 weeks later, and then observed and analyzed by transmission electron microscopy (TEM), electron diffraction, and electron microprobes. The results showed that (1) apatitic microcrystals appeared by ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/pl00005825
更新日期：1999-05-01 00:00:00
abstract：:The extracellular protein matrix of developing enamel includes a major class of proteins, the amelogenins, which are believed to be concerned in regulating enamel biomineralization. Previous studies have shown the amelogenins of the extracellular matrix to be a complex of proline-rich hydrophobic proteins which, it is...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02556044
更新日期：1989-10-01 00:00:00
abstract：:Observational studies examining associations of smoking and alcohol consumption with bone mineral density (BMD) have generated inconsistent results and suffer from several methodological limitations. We aim to evaluate whether there are causal associations between smoking, alcohol consumption, and BMD using a Mendelia...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-018-0452-y
更新日期：2018-11-01 00:00:00
abstract：:Proton pump inhibitors are taken by millions of patients for prevention and treatment of gastroesophageal diseases. Case-control studies have suggested that use of omeprazole is associated with an increased risk of hip fractures. The aim of this prospective study was to assess the risk of vertebral fractures in postme...
journal_title：Calcified tissue international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00223-008-9188-4
更新日期：2009-01-01 00:00:00
abstract：:We have used in situ hybridization to examine expression of collagen type I, II, and X mRNA and osteonectin mRNA in the chick epiphysis. Tissue samples from the proximal tibial growth cartilage were fixed in modified Carnoy's solution, dehydrated in ethanol, and embedded in paraffin. Longitudinal and transverse sectio...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02556062
更新日期：1989-09-01 00:00:00
abstract：:We measured serum concentrations of bone Gla-protein (osteocalcin, BGP) and carboxyterminal propeptide of type I procollagen (PICP) in 14 patients with active acromegaly. Blood was collected at 0800 for measurement of bone Gla-protein (BGP), carboxyterminal propeptide of type I procollagen (PICP), and insulin-like gro...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF00298716
更新日期：1993-03-01 00:00:00
abstract：:Dickkopf-1 (DKK1) and sclerostin are antagonists of the Wnt/β-catenin pathway and decreased expression of either results in increased bone formation and mass. As both affect the same signaling pathway, we aimed to elucidate the redundancy and/or compensation of sclerostin and DKK1. Weekly sclerostin antibody (Scl-Ab) ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-018-0420-6
更新日期：2018-09-01 00:00:00
