Temporal relationship between bone loss and increased bone turnover in ovariectomized rats.

abstract：:Normal rat bone maturation has been studied using biochemical methods and hydrazine separation of matrix and mineral for X-ray diffraction. In the bone, the amount of mineral increases between 4 and 22 weeks of age, while in the matrix, the ratio of noncollagenous protein to collagen progressively decreases. In minera...

journal_title：Calcified tissue international

authors： Burnell JM,Teubner EJ,Miller AG

更新日期：1980-01-01 00:00:00

abstract：:We separated osteoclasts from bone and observed the effect of several known and potential mediators of the control of bone resorption on their cytoplasmic motility. We already found that calcitonin (CT), a hormone that inhibits bone resorption, regularly causes complete inhibition of cytoplasmic motility, specific for...

journal_title：Calcified tissue international

authors： Chambers TJ,Dunn CJ

更新日期：1983-07-01 00:00:00

abstract：:Synovial fluid basic calcium phosphate (BCP) crystals are associated with severe destructive arthropathy. BCP crystals induce the secretion of matrix-degrading enzymes such as collagenase. No prophylactic or therapeutic agents are recognized to ameliorate the cartilage damage associated with BCP deposits in joints. As...

journal_title：Calcified tissue international

authors： McCarthy GM,Mitchell PG,Cheung HS

更新日期：1993-06-01 00:00:00

abstract：:Forty 5-week-old rats were randomly divided into 1 control group given a normal diet and water low in fluoride (0.026 mM/1) and experimental group receiving the same basic diet and a fluoride supplement of 2.6 mMol/l in the drinking water. After 30 weeks, half of the fluoride-supplemented and half of the nonsupplement...

journal_title：Calcified tissue international

authors： Rosenquist JB,Lorentzon PR,Boquist LL

更新日期：1983-07-01 00:00:00

abstract：:Hypophosphatemic rickets (HR) is a group of rare disorders caused by excessive renal phosphate wasting. The purpose of this cross-sectional study of 38 HR patients was to characterize the phenotype of adult HR patients. Moreover, skeletal and endodontic severity scores were defined to assess possible gender difference...

journal_title：Calcified tissue international

authors： Beck-Nielsen SS,Brusgaard K,Rasmussen LM,Brixen K,Brock-Jacobsen B,Poulsen MR,Vestergaard P,Ralston SH,Albagha OM,Poulsen S,Haubek D,Gjørup H,Hintze H,Andersen MG,Heickendorff L,Hjelmborg J,Gram J

更新日期：2010-08-01 00:00:00

abstract：:As the correlation of bone mass from childhood to adulthood is unclear, we conducted a long-term prospective observational study to determine if a pediatric bone mass scan could predict adult bone mass. We measured cortical bone mineral content (BMC [g]), bone mineral density (BMD [g/cm(2)]), and bone width (cm) in th...

journal_title：Calcified tissue international

authors： Buttazzoni C,Rosengren BE,Tveit M,Landin L,Nilsson JÅ,Karlsson MK

更新日期：2014-02-01 00:00:00

abstract：:We investigated the ultrastructural distribution and histochemical properties of sulfated glycoconjugates, which could be preserved by glutaraldehyde fixation, in secretory ameloblasts and developing enamel matrix, by use of the high iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining and enzymatic...

journal_title：Calcified tissue international

authors： Kogaya Y,Furuhashi K

更新日期：1988-11-01 00:00:00

abstract：:Bone mineralization density distribution (BMDD) is an important determinant of bone mechanical properties. The most available skeletal site for access to the BMDD is the iliac crest. Compared to cancellous bone much less information on BMDD is available for cortical bone. Hence, we analyzed complete transiliac crest b...

journal_title：Calcified tissue international

authors： Misof BM,Dempster DW,Zhou H,Roschger P,Fratzl-Zelman N,Fratzl P,Silverberg SJ,Shane E,Cohen A,Stein E,Nickolas TL,Recker RR,Lappe J,Bilezikian JP,Klaushofer K

更新日期：2014-10-01 00:00:00

abstract：:This study sought to confirm that osteoblasts of C3H/HeJ (C3H) mice, which have higher differentiation status and bone-forming ability compared to C57BL/6J (B6) osteoblasts, also have a lower apoptosis level and to test whether the higher differentiation status and bone-forming ability of C3H osteoblasts were related ...

journal_title：Calcified tissue international

authors： Sheng MH,Lau KH,Mohan S,Baylink DJ,Wergedal JE

更新日期：2006-05-01 00:00:00

abstract：:In vitro models of osteogenesis are essential for investigating bone biology and the effects of pharmaceutical, chemical, and physical cues on bone formation. Osteogenesis takes place in a complex three-dimensional (3D) environment with cells from both mesenchymal and hematopoietic origins. Existing in vitro models of...

journal_title：Calcified tissue international

authors： Gurkan UA,Kishore V,Condon KW,Bellido TM,Akkus O

更新日期：2011-05-01 00:00:00

abstract：:Irrespective of the method used for noninvasive bone mass determination, data comparison between different centers is a major problem as significant interunit variation may occur. We, therefore, have employed mobile densitometry units to reduce interunit variability in two large epidemiologic studies in Germany. Two c...

journal_title：Calcified tissue international

authors： Wapniarz M,Lehmann R,Randerath O,Baedeker S,John W,Klein K,Allolio B

更新日期：1994-03-01 00:00:00

abstract：:We have examined the effect of the anti-tumor compound taxol, on osteoclastic bone resorption. In the bone slice assay, taxol (0.1-0.001 microM) dose-dependently inhibited bone resorption with an IC50 of 0.08 microM. Osteoclast survival on bone slices was unaffected by 0.01-1 microM taxol, but 10 microM was cytotoxic....

journal_title：Calcified tissue international

authors： Hall TJ,Jeker H,Schaueblin M

更新日期：1995-12-01 00:00:00

abstract：:Syndesmophyte occurrence and axial bone loss were investigated in the heterozygous Tg187 tumor necrosis factor (TNF) transgenic mouse model (Tg-huTNF) of arthritis. Female and male Tg-huTNF mice were compared to wild-type mice (WT) at 2, 4, 6, 8, and 10 weeks. Syndesmophytes, intervertebral disc space, osteoclasts, os...

journal_title：Calcified tissue international

authors： Courbon G,Flammier S,Laroche N,Vico L,Marotte H,Coury F

更新日期：2017-06-01 00:00:00

abstract：:The definition of osteoporosis was based for several years on bone mineral density values, which were used by most guidelines for defining treatment thresholds. The availability of tools for the estimation of fracture risk, such as FRAX™ or its adapted Italian version, DeFRA, is providing a way to grade osteoporosis s...

journal_title：Calcified tissue international

authors： Adami S,Bertoldo F,Gatti D,Minisola G,Rossini M,Sinigaglia L,Varenna M

更新日期：2013-09-01 00:00:00

abstract：:The purpose of this study was to investigate the mineral induction capacity in vitro of polyanionic proteins covalently bound to a surface. Rat dentin gamma-carboxyglutamate-containing protein of the osteocalcin type (Gla-protein), proteoglycan (PG), and phosphoprotein (PP-H), as well as phosvitin (PhV) and bovine ser...

journal_title：Calcified tissue international

authors： Linde A,Lussi A,Crenshaw MA

更新日期：1989-04-01 00:00:00

abstract：:Postmenopausal osteoporosis induced by estrogen deficiency causes inadequate new bone formation and affects millions of women worldwide. Melatonin can improve bone mineral density at the femoral neck in postmenopausal women with osteopenia. This study aimed to investigate the mechanism of melatonin in estrogen deficie...

journal_title：Calcified tissue international

authors： Xu L,Zhang L,Wang Z,Li C,Li S,Li L,Fan Q,Zheng L

更新日期：2018-10-01 00:00:00

abstract：:Bone mineral content (BMC) and bone mineral density (BMD) are common but imperfect surrogate measures of bone strength. The mechanical response tissue analyzer is a device that measures long bone bending stiffness (EI), which strongly predicts bone breaking strength. We hypothesized that isokinetic resistance training...

journal_title：Calcified tissue international

authors： Miller LE,Nickols-Richardson SM,Wootten DF,Ramp WK,Steele CR,Cotton JR,Carneal JP,Herbert WG

更新日期：2009-06-01 00:00:00

abstract：:The effects of fluoride on human enamel and selachian enameloid in vitro were visualized in TEM and analyzed with electron diffraction. It is demonstrated that under precise pH conditions, inducing concentration balance between F-ions and apatite, calcium fluoride is no longer formed, and crystalline changes occur ins...

journal_title：Calcified tissue international

authors： Daculsi G,Kerebel LM,Kerebel B

更新日期：1981-01-01 00:00:00

abstract：:This study investigated whether bone turnover influences the response to alendronate in women with postmenopausal osteoporosis. One hundred postmenopausal osteoporotic women were randomized to receive either alendronate (10 mg/day) plus calcium (1000 mg/day) (n = 50) or calcium alone (n = 50). Vertebral and radial bon...

journal_title：Calcified tissue international

authors： Gonnelli S,Cepollaro C,Pondrelli C,Martini S,Montagnani A,Monaco R,Gennari C

更新日期：1999-11-01 00:00:00

abstract：:The gut microbiota (GM) is the whole of commensal, symbiotic, and pathogenic microorganisms living in our intestine. The GM-host interactions contribute to the maturation of the host immune system, modulating its systemic response. It is well documented that GM can interact with non-enteral cells such as immune cells,...

journal_title：Calcified tissue international

authors： D'Amelio P,Sassi F

更新日期：2018-04-01 00:00:00

abstract：:Calcium-acidic phospholipid-phosphate complexes (Ca-PL-PO4) cause hydroxyapatite (HA) deposition in vitro. The acidic phospholipids--phosphatidylserine (PS), phosphatidylinositol (PI), phosphatidylglycerol (PG), and diphosphatidylglycerol (DPG)--all form Ca-PL-PO4 complexes: Nonacidic phospholipids--sphingomyelin (SPL...

journal_title：Calcified tissue international

authors： Boskey AL,Posner AS

更新日期：1982-01-01 00:00:00

abstract：:The relationship between bisphosphonate-induced bone mineral density (BMD) gains and antifracture efficacy remains to be fully elucidated. Data from two antifracture studies were analyzed. Postmenopausal osteoporotic women received oral (2.5 mg daily, 20 mg intermittent) or intravenous (0.5 mg, 1 mg quarterly) ibandro...

journal_title：Calcified tissue international

authors： Miller PD,Delmas PD,Huss H,Patel KM,Schimmer RC,Adami S,Recker RR

更新日期：2010-10-01 00:00:00

abstract：:It is our hypothesis that interstitial fluid flow plays a role in the bone remodeling response to mechanical loading. The fluid flow-induced expression of three proteins (collagen, osteopontin, and alkaline phosphatase) involved in bone remodeling was investigated. Rat calvarial osteoblasts subjected to pulsatile flui...

journal_title：Calcified tissue international

authors： Hillsley MV,Frangos JA

更新日期：1997-01-01 00:00:00

abstract：:Prostaglandin E2 and leukotriene B4 are metabolites of arachidonic acid with well-characterized effects on osteoblastic cells. Prostaglandin E2 has been shown to be a potent bone-resorbing agent and to stimulate as well as inhibit osteoblastic cell proliferation. Leukotriene B4 has also been demonstrated to stimulate ...

journal_title：Calcified tissue international

authors： Ren W,Kinniburgh AJ,Dziak R

更新日期：1992-04-01 00:00:00

abstract：:The aim of this study was to investigate the relation between birth weight and calcaneal bone stiffness in a large sample of Belgian, healthy, preadolescent children. Participants were 827 children (3.6-11.2 years, 51.6 % boys) from the Belgian cohort of the IDEFICS study. Birth weight was obtained using a parental qu...

journal_title：Calcified tissue international

authors： Van den Bussche K,Michels N,Gracia-Marco L,Herrmann D,Eiben G,De Henauw S,Sioen I

更新日期：2012-10-01 00:00:00

abstract：:Using data from the Peking Vertebral Fracture Study, we conducted a longitudinal cohort study to investigate the association between type 2 diabetes mellitus (T2DM) and the risk of incident fractures, especially of vertebral fractures (VFs), and we also examined the modifying effect of body mass index (BMI) on this as...

journal_title：Calcified tissue international

authors： Jiajue R,Qi X,Jiang Y,Wang Q,Wang W,Pei Y,Wang X,Huang W,Zheng X,Ning Z,Wang O,Li M,Xing X,Yu W,Xu L,Xia W

更新日期：2019-11-01 00:00:00

abstract：:Periodic fringes corresponding to six different lattice planes have been observed in apatite crystals of human normal alveolar bone by transmission electron microscopy. Three of these sets of fringes have spacings less than 3.5 A corresponding to the Scherzer resolution of the microscope used. The (0002) lattice plane...

journal_title：Calcified tissue international

authors： Cuisinier F,Bres EF,Hemmerle J,Voegel JC,Frank RM

更新日期：1987-06-01 00:00:00

abstract：:Gallium nitrate (GaN) reduces cancer-related hypercalcemia and inhibits bone resorption in vitro. This study investigated the effects of chronic GaN administration on bone, kidney, and parathyroid gland activity of growing rats. Experimental animals received GaN (1.75 mg elemental gallium i.p. QOD X 8, Ga+), and contr...

journal_title：Calcified tissue international

authors： Cournot-Witmer G,Bourdeau A,Lieberherr M,Thil CL,Plachot JJ,Enault G,Bourdon R,Balsan S

更新日期：1987-05-01 00:00:00

abstract：:ELISAs for measuring the urinary excretion of collagen crosslinks and related peptides appear to show marked differences in sensitivity to anti-resorptive therapy. This presumably reflects variations in specificity of the anylate being detected in these assays, and the way in which they respond to treatment. To clarif...

journal_title：Calcified tissue international

authors： Tobias JH,Laversuch CV,Wilson N,Robins SP

更新日期：1996-11-01 00:00:00

abstract：:Octacalcium phosphate (Ca8H2(PO4)6 . 5H2O) is considered to be precursor in the formation of apatite in bones and teeth; a crucial step for incorporation of impurities appears to occur during its hydrolysis. The present study examines the role that octacalcium phosphate plays in the process of incorporation of carbona...

journal_title：Calcified tissue international

authors： Chickerur NS,Tung MS,Brown WE

更新日期：1980-01-01 00:00:00