Normal maturational changes in bone matrix, mineral, and crystal size in the rat.

abstract：:The low interference with growth expected in child for a cortisol analogue, deflazacort (DFZ), prompted us to verify if DFZ could affect growth less than prednisone (PDN). An interim analysis relative to 27 girls and 38 boys (out of 100 expected) aged 3-12 yrs, after a median period of 14 mo.s is reported. Children wi...

journal_title：Calcified tissue international

authors： Aicardi G,Milani S,Imbimbo B,Vignolo M,Di Battista E,Gusmano R,Terragna A,Cordone G,Cottafava F,Coppo R

更新日期：1991-04-01 00:00:00

abstract：:In adult human bone, fluoride uptake is accompanied by an increase in apatite crystal size. This increase, however, is not isotropic but is restricted primarily to growth in width and/or thickness, with no measurable change in length. In the present study, seeded growth experiments were conducted in vitro to determine...

journal_title：Calcified tissue international

authors： Eanes ED,Hailer AW

更新日期：1998-09-01 00:00:00

abstract：:Because of the variability of collagen crosslinks, their use as markers for bone resorption is often criticized. We hypothesized that the variability could be reduced by collecting urine for 24 hours (or longer) instead of using single voids, and by not normalizing to creatinine. Urine samples were collected from 22 h...

journal_title：Calcified tissue international

authors： Smith SM,Dillon EL,DeKerlegand DE,Davis-Street JE

更新日期：2004-04-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA levels are commonly used as an internal control to normalize gene expression data based on the belief that this gene is constitutively expressed. However, GAPDH mRNA levels increased by more than 2.5-fold in tibiae of hindlimb unloaded female rats compared to L32 m...

journal_title：Calcified tissue international

authors： Maran A,Hefferan TE,Zhang M,Turner RT

更新日期：2004-02-01 00:00:00

abstract：:The purpose of this study was to examine the effects of green tea extract (GTE) intake on bone structural and physiological properties, such as bone mass, trabecular bone microarchitecture, cortical bone geometry, and bone mechanical strength, in growing rats. Four-week-old male Wistar rats were divided into the follo...

journal_title：Calcified tissue international

authors： Minematsu A,Nishii Y,Imagita H,Sakata S

更新日期：2018-03-01 00:00:00

abstract：:High impact loading is known to prevent some of the age-related bone loss but its effects on the density distribution of cortical bone are relatively unknown. This study examined the effects of age and habitual sprinting on tibial and fibular mid-shaft bone traits (structural, cortical radial and polar bone mineral de...

journal_title：Calcified tissue international

authors： Rantalainen T,Duckham RL,Suominen H,Heinonen A,Alén M,Korhonen MT

更新日期：2014-08-01 00:00:00

abstract：:Osteonectin, gamma-carboxyglutamic acid-containing (Gla) protein, and dentin phosphoprotein were covalently attached to sepharose beads and inoculated in solutions at two different degrees of supersaturation with respect to both octacalcium phosphate (OCP) and hydroxyapatite. In both solutions, the inhibitory activity...

journal_title：Calcified tissue international

authors： Doi Y,Horiguchi T,Kim SH,Moriwaki Y,Wakamatsu N,Adachi M,Shigeta H,Sasaki S,Shimokawa H

更新日期：1993-02-01 00:00:00

abstract：:Previous studies have indicated that children with inflammatory bowel disease (IBD) may not achieve optimal bone mass. We evaluated the skeletal characteristics in children and adolescents with IBD. This cross-sectional cohort study comprised 80 IBD patients (median age 14.9 years, range 5-20) with a median disease du...

journal_title：Calcified tissue international

authors： Laakso S,Valta H,Verkasalo M,Toiviainen-Salo S,Viljakainen H,Mäkitie O

更新日期：2012-08-01 00:00:00

abstract：:The potassium pyroantimonate technique was utilized for the selective subcellular localization of calcium in the mandibular condylar cartilage of 1-day-old rats. Electron dense calcium pyroantimonate precipitates were localized principally in mitochondria and at the cell membrane of the chondrocytes. In addition, smal...

journal_title：Calcified tissue international

authors： Morris DC,Appleton J

更新日期：1980-01-01 00:00:00

abstract：:In 11 postmenopausal women with histologically proven osteoporosis and normal lactose tolerance, a direct correlation between calcium absorption and intestinal lactase activity was observed. The results suggest that varying degrees of relative deficiencies in intestinal lactase might contribute to the graded decrease ...

journal_title：Calcified tissue international

authors： Pacifici R,Droke D,Avioli LV

更新日期：1985-01-01 00:00:00

abstract：:The absorption kinetics of intranasal salmon calcitonin were assessed in 4 normal subjects and 9 patients with Klinefelter's syndrome. After administration, absorption occurred within 5 minutes. There was a highly significant correlation between the amount administered and the amount absorbed (r = -0.83, P less than 0...

journal_title：Calcified tissue international

authors： Pun KK,Chan LW,Lau P,Ho PW,Wang C

更新日期：1990-02-01 00:00:00

abstract：:Hepatitis C treatment with interferon alpha-2b (IFN-alpha) and ribavirin has been related to decreased bone mineral density. The aim of this study was to investigate the in vitro effects of different concentrations of ribavirin and IFN-alpha on osteoblast-like cells. Human osteoblast-like cells obtained by the outgrow...

journal_title：Calcified tissue international

authors： Moreira RO,Balduíno A,Martins HS,Reis JS,Duarte ME,Farias ML,Borojevic R

更新日期：2004-08-01 00:00:00

abstract：:This study aims to test the hypothesis that noninvasive bone mass measurements can be used to predict bone strength in a piglet model. Dual energy X-ray absorptiometry measurements of bone mineral content (BMC), bone mineral density (BMD), and bone area (BA) were obtained from four sets of bones (left and right humeri...

journal_title：Calcified tissue international

authors： Koo MW,Yang KH,Begeman P,Hammami M,Koo WW

更新日期：2001-04-01 00:00:00

abstract：:The DMS Lexxos is the first cone-beam dual X-ray absorptiometry (DXA) system capable of performing bone mineral density (BMD) measurements of the spine and hip. By using a two-dimensional (2-D) detector array rather than the linear array used with conventional fan-beam DXA systems, image acquisition time on Lexxos is ...

journal_title：Calcified tissue international

authors： Blake GM,Knapp KM,Fogelman I

更新日期：2005-02-01 00:00:00

abstract：:Osteoporosis is a common disease among patients undergoing transplantation. Its prevalence and complications have been well described in solid organ recipients, especially kidney, liver, and heart. However, studies in bone marrow transplantation (BMT) are scarce. Among the mechanisms invoked in the pathogenesis of BMT...

journal_title：Calcified tissue international

authors： Castañeda S,Carmona L,Carvajal I,Arranz R,Díaz A,García-Vadillo A

更新日期：1997-04-01 00:00:00

abstract：:SUMMARY. The high variation often observed in the ex vivo fibroblastic-colony forming unit (CFU-f) assay is likely to be due to both biological and experimental variation. To determine whether we could improve experimental methods we developed an alternative method of bone marrow cell (BMC) isolation employing a centr...

journal_title：Calcified tissue international

authors： Dobson KR,Reading L,Haberey M,Marine X,Scutt A

更新日期：1999-11-01 00:00:00

abstract：:Men and women (n = 518) receiving moderate-to-high doses of corticosteroids were enrolled in two studies with similar protocols and randomly assigned to receive either placebo or risedronate (2.5 or 5 mg) for 1 year. All patients received daily calcium supplementation (500-1000 mg), and most also received supplemental...

journal_title：Calcified tissue international

authors： Wallach S,Cohen S,Reid DM,Hughes RA,Hosking DJ,Laan RF,Doherty SM,Maricic M,Rosen C,Brown J,Barton I,Chines AA

更新日期：2000-10-01 00:00:00

abstract：:A 56 year-old man with a 2-year history of transitional-cell carcinoma of the urinary bladder presented with back pain and diffuse radiological osteosclerosis. Laboratory studies revealed borderline-low ionized serum calcium, and markedly elevated serum alkaline phosphatase (ALP) activity and serum osteocalcin. Serum ...

journal_title：Calcified tissue international

authors： Liel Y,Maor E,Ariad S,Lowenthal MN

更新日期：1998-12-01 00:00:00

abstract：:The values of in vivo T1 relaxation time (T1) of phosphorus atoms of wrist bone have been measured by phosphorus-31 magnetic resonance spectroscopy (MRS) in 65 menopausal women separated into three groups: (1) age-matched women without any paraclinical or clinical osteoporosis; (2) patients with paraclinical osteoporo...

journal_title：Calcified tissue international

authors： Confort-Gouny S,Mattéi JP,Vion-Dury J,Roux H,Bisset JP,Cozzone PJ

更新日期：1995-06-01 00:00:00

abstract：:Raf-1, the product of proto-oncogene c-raf-1, has key roles in the signal transduction pathways within the cell. The molecular mechanisms of tooth development in the mouse embryo are not known in detail. We examined the expression of Raf-1 during subsequent tooth development by immunohistochemical analysis. In mouse e...

journal_title：Calcified tissue international

authors： Sunohara M,Tanzawa H,Kaneko Y,Fuse A,Sato K

更新日期：1996-01-01 00:00:00

abstract：:The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...

journal_title：Calcified tissue international

authors： Heervä E,Leinonen P,Kuorilehto T,Peltonen S,Pöyhönen M,Väänänen K,Peltonen J

更新日期：2013-01-01 00:00:00

abstract：:The prevalence rates of ossification of the posterior longitudinal ligament (OPLL) in the Korean population were reported as 3.4 and 0.6%. However, these studies were performed before the era of three-dimensional computed tomography (3D CT). We investigated the prevalence of cervical OPLL on the basis of 3D CT and fea...

journal_title：Calcified tissue international

authors： Sohn S,Chung CK,Yun TJ,Sohn CH

更新日期：2014-06-01 00:00:00

abstract：:Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius...

journal_title：Calcified tissue international

authors： Nijs J,Van Essche E,De Munck M,Dequeker J

更新日期：2000-07-01 00:00:00

abstract：:X-linked hypophosphatemia (XLH) is a rare, inheritable disorder manifesting as rickets in children and osteomalacia in adults. While conventional medical treatment with oral phosphate and alfacalcidol is recommended in childhood, it is undecided whether adults should continue therapy. The aim of this 6-year prospectiv...

journal_title：Calcified tissue international

authors： Shanbhogue VV,Hansen S,Jørgensen NR,Beck-Nielsen SS

更新日期：2018-03-01 00:00:00

abstract：:Although radiogenic free radicals are widely used as molecular probes in biological calcified tissues, their nature and their location remain controversial. In the present study we have synthesized and irradiated apatites in which 13CO3(2-) ions substitute hydroxyl or phosphate ions in hydroxyapatite. The 13C-coupling...

journal_title：Calcified tissue international

authors： Geoffroy M,Tochon-Danguy HJ

更新日期：1982-01-01 00:00:00

abstract：:Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However, questions still persist concerning the effect of these drugs on bone properties such as ultrastructure and quality, particularly in the growing patient. To addres...

journal_title：Calcified tissue international

authors： Camacho NP,Raggio CL,Doty SB,Root L,Zraick V,Ilg WA,Toledano TR,Boskey AL

更新日期：2001-08-01 00:00:00

abstract：:Skeletal tissues contain, apart from cells of the osteogenic and chondrogenic lineage, cells of hemopoietic origin, e.g., macrophages, osteoclasts, and their precursors. In the present study we examined the sensitivity for extracellular ATP4- of the above-mentioned cell types in freshly isolated, bone-derived cell pop...

journal_title：Calcified tissue international

authors： Modderman WE,Weidema AF,Vrijheid-Lammers T,Wassenaar AM,Nijweide PJ

更新日期：1994-08-01 00:00:00

abstract：:Dual-photon absorptiometry (153Gd) was used to measure bone mineral of the total body and major anatomical areas. Patients with osteoporosis (male = 11, female = 18) and with renal osteodystrophy (n = 17) were significantly below (20%) normal females (n = 72) and males (n = 13) at most sites. In the osteoporotic patie...

journal_title：Calcified tissue international

authors： Mazess RB,Peppler WW,Chesney RW,Lange TA,Lindgren U,Smith E Jr

更新日期：1984-01-01 00:00:00

abstract：:Inorganic phosphate (P(i)) can regulate the level of skeletal alkaline phosphatase (ALP) activity in human osteoblast-like cells, but not by means of changes in transcription or release from the cell surface. The current studies were intended to determine whether (1) P(i) affected the inactivation of ALP activity in h...

journal_title：Calcified tissue international

authors： Farley JR

更新日期：1995-11-01 00:00:00

abstract：:Pyrolyzed scales, fin spines, and bone from the ray-finned bony fish Polypterus (Actinopterygii) showed two mineral phases on X-ray diffraction: hydroxyapatite (HA), Ca5(PO4)3OH, and whitlockite, Ca3(PO4)2. The ratio of HA/whitlockite varied with the structure (scale, spine, bone) within each individual fish. The rela...

journal_title：Calcified tissue international

authors： Meinke DK,Skinner HC,Thomson KS

更新日期：1979-08-24 00:00:00