Intestinal lactase activity and calcium absorption in the aging female with osteoporosis.

abstract：:Thyroparathyroidectomized rats fed a diet containing 1.2% calcium, 0.55% phosphorus maintain normal serum levels of these ions. Treatment of such rats with parathyroid extract (PTE; 20 U/100 g twice daily; 10 days) has no statistically significant effect on rates of bone formation, matrix apposition, or osteoid matura...

journal_title：Calcified tissue international

authors： Rader JI,Howard GA,Feist E,Turner RT,Baylink DJ

更新日期：1979-11-01 00:00:00

abstract：:Using a combination of gel filtration and DEAE-cellulose chromatography, together with small-scale preparative polyacrylamide gel electrophoresis, we isolated five proteins (amelogenins) from demineralized bovine fetal dental enamel matrix. These purified proteins were characterized by amino acid analysis and gel elec...

journal_title：Calcified tissue international

authors： Fincham AG

更新日期：1979-03-13 00:00:00

abstract：:Quantitative trait locus analysis can be used to identify genes critically involved in biological processes. No such analysis has been applied to identifying genes that control bone fracture healing. To determine the feasibility of such an approach, healing of femur fractures was measured between C57BL/6, DBA/2, and C...

journal_title：Calcified tissue international

authors： Manigrasso MB,O'Connor JP

更新日期：2008-06-01 00:00:00

abstract：:Seventy-two eugonadal women, mean age 39 +/- 4 years, with a z score for total body bone mineral content (BMC) of less than -1.5 (mean -1.80 +/- 0.12) were selected from a previous screening study of normal values of total body and regional BMC in women using dual-energy X-ray absorptiometry. The women were distribute...

journal_title：Calcified tissue international

authors： Rico H,Revilla M,Villa LF,Alvarez de Buergo M,Arribas I

更新日期：1994-06-01 00:00:00

abstract：:We conducted a case-control study on fracture risk associated with the use of orally administered prednisolone/prednisone, budesonide, methylprednisolone, and hydrocortisone to assess if the various preparations were associated with different fracture patterns. Cases were all subjects with any fracture sustained durin...

journal_title：Calcified tissue international

authors： Vestergaard P,Rejnmark L,Mosekilde L

更新日期：2008-04-01 00:00:00

abstract：:Previous observational studies have identified various risk factors associated with the development of osteoporosis, including sex hormone-binding globulin (SHBG). The aim of this study was to determine the potential causal effects of circulating SHBG concentrations on bone mineral density (BMD). Two-sample Mendelian ...

journal_title：Calcified tissue international

authors： Qu Z,Jiang J,Yang F,Huang J,Zhao J,Yan S

更新日期：2020-10-17 00:00:00

abstract：:The association of dietary patterns and bone health is not yet well known, and findings from the rare previous studies conducted on this issue are contradictory. We assessed the dietary patterns in relation to bone mineral density (BMD) in a sample of menopausal Iranian women. In this cross-sectional study, 160 menopa...

journal_title：Calcified tissue international

authors： Karamati M,Jessri M,Shariati-Bafghi SE,Rashidkhani B

更新日期：2012-07-01 00:00:00

abstract：:This randomized, double-blind study assessed the antifracture efficacy and safety of intermittent intravenous (IV) ibandronate versus oral daily risedronate in Japanese patients with primary osteoporosis. Ambulatory patients aged ≥60 years were randomized to receive 0.5 or 1 mg/month IV ibandronate plus oral daily pla...

journal_title：Calcified tissue international

authors： Nakamura T,Nakano T,Ito M,Hagino H,Hashimoto J,Tobinai M,Mizunuma H,MOVER Study Group.

更新日期：2013-08-01 00:00:00

abstract：:We have previously noted that a relatively large load (150 N) is required to induce a strain on the cortex of rat vertebrae similar to that induced on weight-bearing bones by normal mechanical usage. It seems unlikely that the musculature of the tail normally imposes loads of this magnitude, and this suggests that the...

journal_title：Calcified tissue international

authors： Chow JW,Jagger CJ,Chambers TJ

更新日期：1996-08-01 00:00:00

abstract：:Although hypogonadism is a risk factor for bone loss and fractures, the different etiopathophysiology and hormonal profile of classical and obesity-induced hypogonadism may lead to differences in musculoskeletal profile. This is a cross-sectional study of hypogonadal men between 40 and 74 years old. Our outcomes inclu...

journal_title：Calcified tissue international

authors： Aguirre LE,Colleluori G,Dorin R,Robbins D,Chen R,Jiang B,Qualls C,Villareal DT,Armamento-Villareal R

更新日期：2017-12-01 00:00:00

abstract：:Quantitative ultrasound measurement (QUS) and bone mineral density (BMD) have each been shown to predict fracture risk in women. The present study examined whether a combination of QUS and BMD could improve the predictive accuracy of fracture risk. This is a population-based prospective study which involved 454 women ...

journal_title：Calcified tissue international

authors： Chan MY,Nguyen ND,Center JR,Eisman JA,Nguyen TV

更新日期：2012-02-01 00:00:00

abstract：:Genome-wide association studies (GWAS) have demonstrated that genetic variation at the MADS box transcription enhancer factor 2, polypeptide C (MEF2C) locus is robustly associated with bone mineral density, primarily at the femoral neck. MEF2C is a transcription factor known to operate via the Wnt signaling pathway. O...

journal_title：Calcified tissue international

authors： Johnson ME,Deliard S,Zhu F,Xia Q,Wells AD,Hankenson KD,Grant SF

更新日期：2014-04-01 00:00:00

abstract：:The low interference with growth expected in child for a cortisol analogue, deflazacort (DFZ), prompted us to verify if DFZ could affect growth less than prednisone (PDN). An interim analysis relative to 27 girls and 38 boys (out of 100 expected) aged 3-12 yrs, after a median period of 14 mo.s is reported. Children wi...

journal_title：Calcified tissue international

authors： Aicardi G,Milani S,Imbimbo B,Vignolo M,Di Battista E,Gusmano R,Terragna A,Cordone G,Cottafava F,Coppo R

更新日期：1991-04-01 00:00:00

abstract：:Micro-computed tomography (microCT) has become a standard tool for the evaluation of bone morphology in preclinical studies. Unfortunately, the user-dependent definition of contour lines that separate trabecular from cortical bone is not only extremely time-consuming but may also represent a source of data bias and in...

journal_title：Calcified tissue international

authors： Lublinsky S,Ozcivici E,Judex S

更新日期：2007-10-01 00:00:00

abstract：:To define the quantitative aspects of ossification of human fetal spine, we performed a high resolution densitometric study by lateral and postero-anterior scanning of five fetal spines (18-36 weeks of conceptual age) and one spine of a 4-month-old infant. The data were plotted against developmental age for each spine...

journal_title：Calcified tissue international

authors： Panattoni GL,Sciolla A,Isaia GC

更新日期：1995-07-01 00:00:00

abstract：:Raman spectroscopy has been used to demonstrate, for the first time, that calcium mineralization in the core of the major lateral teeth of the chiton Acanthopleura echinata takes place as an ordered process, with crystalline carbonated apatite being the first mineral deposited. Deposition begins at the top of the toot...

journal_title：Calcified tissue international

authors： Lee AP,Brooker LR,Macey DJ,van Bronswijk W,Webb J

更新日期：2000-11-01 00:00:00

abstract：:Parameters of mineral metabolism were examined in 6 patients with moderately severe anticonvulsant drug-induced osteomalacia. Compared to 15 matched controls, the patients exhibited significantly reduced serum calcium, inorganic phosphate, and 25-hydroxyvitamin D concentration, elevated serum alkaline phosphatase and ...

journal_title：Calcified tissue international

authors： Hahn TJ,Halstead LR

更新日期：1979-03-13 00:00:00

abstract：:Ectopic calcification of diseased tissues or around prosthetic implants can lead to serious disability. Therefore, calcification of implants of glutaraldehyde-cross-linked collagenous tissues and reconstituted collagen was compared with mineralization induced by demineralized bone matrix (DBM). Whereas implants of DBM...

journal_title：Calcified tissue international

authors： Nimni ME,Bernick S,Cheung DT,Ertl DC,Nishimoto SK,Paule WJ,Salka C,Strates BS

更新日期：1988-05-01 00:00:00

abstract：:Humanin (HN), a mitochondrial derived peptide, plays cyto-protective role under various stress. In this study, we aimed to investigate the effects of HNGF6A, an analogue of HN, on osteoblast apoptosis and differentiation and the underlying mechanisms. Cell proliferation of murine osteoblastic cell line MC3TC-E1 was ex...

journal_title：Calcified tissue international

authors： Zhu X,Zhao Z,Zeng C,Chen B,Huang H,Chen Y,Zhou Q,Yang L,Lv J,Zhang J,Pan D,Shen J,Duque G,Cai D

更新日期：2020-05-01 00:00:00

abstract：:This study sought to confirm that osteoblasts of C3H/HeJ (C3H) mice, which have higher differentiation status and bone-forming ability compared to C57BL/6J (B6) osteoblasts, also have a lower apoptosis level and to test whether the higher differentiation status and bone-forming ability of C3H osteoblasts were related ...

journal_title：Calcified tissue international

authors： Sheng MH,Lau KH,Mohan S,Baylink DJ,Wergedal JE

更新日期：2006-05-01 00:00:00

abstract：:The development of prophylaxes and treatments of bone diseases that can effectively increase the strength of bone as a structure necessitates a better understanding of the time course by which chemical properties define the stiffness of the material during primary and secondary mineralization. It was hypothesized that...

journal_title：Calcified tissue international

authors： Busa B,Miller LM,Rubin CT,Qin YX,Judex S

更新日期：2005-12-01 00:00:00

abstract：:Recommendations from the FNIH Sarcopenia Project are that appendicular lean mass (ALM, kg) adjusted for body mass index (BMI, kg/m2) be used for identifying low lean mass, with ALM/BMI cutpoints of < 0.789 m2 for men and < 0.512 m2 for women. We report normative ALM/BMI values for Australian adults, and compare the pe...

journal_title：Calcified tissue international

authors： Pasco JA,Holloway-Kew KL,Tembo MC,Sui SX,Anderson KB,Rufus-Membere P,Hyde NK,Williams LJ,Kotowicz MA

更新日期：2019-04-01 00:00:00

abstract：:Skeletal tissues contain, apart from cells of the osteogenic and chondrogenic lineage, cells of hemopoietic origin, e.g., macrophages, osteoclasts, and their precursors. In the present study we examined the sensitivity for extracellular ATP4- of the above-mentioned cell types in freshly isolated, bone-derived cell pop...

journal_title：Calcified tissue international

authors： Modderman WE,Weidema AF,Vrijheid-Lammers T,Wassenaar AM,Nijweide PJ

更新日期：1994-08-01 00:00:00

abstract：:It has been well established that bone morphogenetic protein-2 (BMP-2) can induce bone formation bothin vivo andin vitro, although high concentrations (up to milligrams) of BMP-2 have been required to achieve this effectin vivo. Further, clinical applications are usually limited to a single dose at the time of implant...

journal_title：Calcified tissue international

authors： Cheng SL,Lou J,Wright NM,Lai CF,Avioli LV,Riew KD

更新日期：2001-02-01 00:00:00

abstract：:This report describes a method using direct photon absorptiometry (DPA) for determination in vivo of the bone mineral content to bone width ratio (BMC/W) in the rat femur. A significant correlation was noted between measurements by DPA and whole femur dry weight and ash weight. Measurements were reproducible within re...

journal_title：Calcified tissue international

authors： Sanchez TV,Myers RC,Bond JT,Mayor GH

更新日期：1981-01-01 00:00:00

abstract：:Gnathodiaphyseal dysplasia (GDD; OMIM#166260) is a rare skeletal disorder which is mainly characterized by cemento-osseous lesions in mandibles, bone fragility, bowing and diaphyseal sclerosis of tubular bones. GDD is caused by point mutations in Anoctamin-5 (ANO5); however, the disease mechanisms remain unclear. Here...

journal_title：Calcified tissue international

authors： Wang X,Liu X,Dong R,Liang C,Reichenberger EJ,Hu Y

更新日期：2019-06-01 00:00:00

abstract：:We studied the acute phase response, including specific cytokine production, [interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor alpha(TNF alpha)] following a single dose of Aredia (disodium pamidronate) in patients with increased bone turnover and, in vitro, the role played by specific cytokines in the...

journal_title：Calcified tissue international

authors： Thiébaud D,Sauty A,Burckhardt P,Leuenberger P,Sitzler L,Green JR,Kandra A,Zieschang J,Ibarra de Palacios P

更新日期：1997-11-01 00:00:00

abstract：:The DMS Lexxos is the first cone-beam dual X-ray absorptiometry (DXA) system capable of performing bone mineral density (BMD) measurements of the spine and hip. By using a two-dimensional (2-D) detector array rather than the linear array used with conventional fan-beam DXA systems, image acquisition time on Lexxos is ...

journal_title：Calcified tissue international

authors： Blake GM,Knapp KM,Fogelman I

更新日期：2005-02-01 00:00:00

abstract：:The primary aim of the project was to determine the combined effect of whole-body electromyostimulation (WB-EMS) and protein supplements on local and overall muscle/fat distribution in older man with sarcopenic obesity (SO). Community-dwelling (cdw) men ≥ 70 years with SO were randomly allocated to a WB-EMS and protei...

journal_title：Calcified tissue international

authors： Kemmler W,Grimm A,Bebenek M,Kohl M,von Stengel S

更新日期：2018-09-01 00:00:00

abstract：:Fracture healing is a natural process that recapitulates embryonic skeletal development. In the early phase after fracture, reactive oxygen species (ROS) are produced under inflammatory and ischemic conditions due to vessel injury and soft tissue damage, leading to cell death. Usually, such damage during the course of...

journal_title：Calcified tissue international

authors： Kubo Y,Wruck CJ,Fragoulis A,Drescher W,Pape HC,Lichte P,Fischer H,Tohidnezhad M,Hildebrand F,Pufe T,Jahr H

更新日期：2019-10-01 00:00:00