Abstract:
:The values of in vivo T1 relaxation time (T1) of phosphorus atoms of wrist bone have been measured by phosphorus-31 magnetic resonance spectroscopy (MRS) in 65 menopausal women separated into three groups: (1) age-matched women without any paraclinical or clinical osteoporosis; (2) patients with paraclinical osteoporosis detected only by dual photonic absorptiometry; and (3) women with clinical osteoporosis with vertebral fractures. No significant differences were found in T1 values in the presence of paraclinical or clinical osteoporosis as compared to control values. No relationships were found among the T1, the value of the Z-score, the value of bone mineral content, the age of patients, the number of their children, and the age of menopause. Phosphorus-31 magnetic resonance spectroscopy of the wrist fails to separate osteoporotic from nonosteoporotic women and cannot be clinically used at this time to perform a noninvasive diagnosis of osteoporosis.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Confort-Gouny S,Mattéi JP,Vion-Dury J,Roux H,Bisset JP,Cozzone PJdoi
10.1007/BF00298583subject
Has Abstractpub_date
1995-06-01 00:00:00pages
529-32issue
6eissn
0171-967Xissn
1432-0827journal_volume
56pub_type
杂志文章abstract::The CYP3A7 enzyme metabolizes some steroid hormones, including dehydroepiandrosterone sulfate (DHEAS). The age-related decline of serum DHEAS levels is believed to contribute to osteoporosis. Previously, the CYP3A7*1C polymorphism has been shown to cause a persistent high CYP3A7 enzyme activity, resulting in lower lev...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-006-0227-8
更新日期:2007-03-01 00:00:00
abstract::The prevalence rates of ossification of the posterior longitudinal ligament (OPLL) in the Korean population were reported as 3.4 and 0.6%. However, these studies were performed before the era of three-dimensional computed tomography (3D CT). We investigated the prevalence of cervical OPLL on the basis of 3D CT and fea...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-014-9846-7
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journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-017-0369-x
更新日期:2018-02-01 00:00:00
abstract::We examined the osteogenesis process in transforming growth factor beta 1 (TGF-beta 1)-treated neonatal and adult rats, aiming to investigate the age difference in the effect of TGF-beta 1 on mesenchymal cell differentiation. Recombinant human (rh) TGF-beta 1 (20 and 200 ng) was injected onto the outer periostea of th...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF01321890
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abstract::Gnathodiaphyseal dysplasia (GDD; OMIM#166260) is a rare skeletal disorder which is mainly characterized by cemento-osseous lesions in mandibles, bone fragility, bowing and diaphyseal sclerosis of tubular bones. GDD is caused by point mutations in Anoctamin-5 (ANO5); however, the disease mechanisms remain unclear. Here...
journal_title:Calcified tissue international
pub_type: 杂志文章
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abstract::MicroRNAs (miRNAs/miRs) are important biomarkers for the progression of intervertebral disc degeneration (IDD). We investigated the role of miR-30d in IDD progression through its interactions with forkhead box O3 (FOXO3) and C-X-C motif ligand 10 (CXCL10). We first measured the expression of miR-30d, FOXO3, and CXCL10...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-020-00760-w
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223001093
更新日期:2000-07-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223001103
更新日期:2000-07-01 00:00:00
abstract::Bone labeling, histochemical, and fine structural studies were performed in order to clarify the effects of ipriflavone (IP) on rat bone tissue in vivo and in vitro. Labeling experiments showed a slight increase in bone formation during 3 days' administration. It was also noted that many osteoclasts detached from the ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02180245
更新日期:1992-01-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555838
更新日期:1988-01-01 00:00:00
abstract::To assess the usefulness of the measurement of the os calcis by ultrasound, a method that probably reflects bone quality as well as density, we have studied 54 women with hip fracture of the proximal femur and a control group. Ultrasound evaluation of the os calcis [broadband ultrasound attenuation (BUA), speed of the...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00310252
更新日期:1995-09-01 00:00:00
abstract::The effects of fluoride on human enamel and selachian enameloid in vitro were visualized in TEM and analyzed with electron diffraction. It is demonstrated that under precise pH conditions, inducing concentration balance between F-ions and apatite, calcium fluoride is no longer formed, and crystalline changes occur ins...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02409406
更新日期:1981-01-01 00:00:00
abstract::Crouzon syndrome is a debilitating congenital disorder involving abnormal craniofacial skeletal development caused by mutations in fibroblast growth factor receptor-2 (FGFR2). Phenotypic expression in humans exhibits an autosomal dominant pattern that commonly involves premature fusion of the coronal suture (craniosyn...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-013-9701-2
更新日期:2013-05-01 00:00:00
abstract::Orthopaedic wear debris induces release of bone-resorbing factors from macrophages and fibroblasts. However, the extent to which elemental metallic particles induce bone cells to express factors contributing to implant loosening remains unclear. This study showed that exposure of MG-63 osteoblast-like cells to titaniu...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223001125
更新日期:2000-08-01 00:00:00
abstract::Prosected vertebrae and phalanges from 32 cadavera were examined using noninvasive methods commonly used for assessment of osteoporosis. Bone measures were then compared with a strength variable obtained by mechanically crushing or breaking the bones. All of the phalangeal density assessment techniques were found to b...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555150
更新日期:1988-08-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02409496
更新日期:1981-01-01 00:00:00
abstract::A comparative polarized light (PLM), scanning (SEM), and transmission (TEM) electron microscopy study was carried out on cross- and longitudinal sections of human lamellar bone in the tibiae of four male subjects aged 9, 23, 45, and 70 years. SEM analysis was also performed on rectangular-prismatic samples in order to...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF01673402
更新日期:1993-01-01 00:00:00
abstract::Although hypogonadism is a risk factor for bone loss and fractures, the different etiopathophysiology and hormonal profile of classical and obesity-induced hypogonadism may lead to differences in musculoskeletal profile. This is a cross-sectional study of hypogonadal men between 40 and 74 years old. Our outcomes inclu...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-017-0316-x
更新日期:2017-12-01 00:00:00
abstract::To test the hypothesis that the relationship between fat mass (FM) and bone mineral density (BMD) is mediated by leptin. The study involved 611 individuals aged 20-89 years who were randomly sampled from Ho Chi Minh City (Vietnam). BMD at the femoral neck (FN), lumbar spine (LS), and whole body (WB) was measured by DX...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-016-0196-5
更新日期:2017-01-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
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更新日期:1992-03-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-007-9010-8
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journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02556669
更新日期:1987-12-01 00:00:00
abstract::To clarify the mechanisms underlying shockwave-induced osteogenesis, we applied shockwave to rat femoral shafts from the ventral side. We assessed bone mineral content (BMC) and bone mineral density (BMD), and analyzed the spatial and temporal gene expression for pro-alpha1 (I) collagen (COL1A1), pro-alpha1 (II) colla...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-003-0043-3
更新日期:2004-02-01 00:00:00
abstract::The effects of the trace metals zinc (Zn), manganese (Mn), and cadmium (Cd) on the metabolism of growth plate chondrocytes was examined using a mineralizing culture system. Supplementation of serum-free primary cultures of growth plate chondrocytes with 10-100 mu m Zn resulted in an increase in cell protein and greatl...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900442
更新日期:1998-04-01 00:00:00
abstract::To assess the reductions in bone mass, strength, and turnover in adjuvant-induced arthritic rats and to examine the effect of a new benzamide compound, DU-6712, on these parameters, a 28-day dosing experiment was performed using 8-week-old female Lewis rats. Arthritis was induced by injecting the adjuvant into the hin...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900472
更新日期:1998-06-01 00:00:00
abstract::To investigate the effect of low doses of intranasal salmon calcitonin on plasma cyclic AMP (cAMP) and serum ionized calcium, 40 healthy postmenopausal women were randomized to receive a single dose of either placebo or 50, 100, or 200 IU of salmon calcitonin as a nasal spray. Blood samples were collected throughout a...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1990-01-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02411269
更新日期:1982-07-01 00:00:00
abstract::ELISAs for measuring the urinary excretion of collagen crosslinks and related peptides appear to show marked differences in sensitivity to anti-resorptive therapy. This presumably reflects variations in specificity of the anylate being detected in these assays, and the way in which they respond to treatment. To clarif...
journal_title:Calcified tissue international
pub_type: 杂志文章
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更新日期:1996-11-01 00:00:00
abstract::In vitro models of osteogenesis are essential for investigating bone biology and the effects of pharmaceutical, chemical, and physical cues on bone formation. Osteogenesis takes place in a complex three-dimensional (3D) environment with cells from both mesenchymal and hematopoietic origins. Existing in vitro models of...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-011-9467-3
更新日期:2011-05-01 00:00:00
abstract::Carboxy-terminal pyridinoline cross-linked telopeptide of type I collagen (ICTP) in serum has recently been proposed as a new biochemical marker of bone resorption. In the present study we compared serum ICTP with radiopharmaceutical and histomorphometric measurements of bone turnover in postmenopausal women with mild...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章
doi:10.1007/BF00316286
更新日期:1994-01-01 00:00:00