Abstract:
:Dual-photon absorptiometry (153Gd) was used to measure bone mineral of the total body and major anatomical areas. Patients with osteoporosis (male = 11, female = 18) and with renal osteodystrophy (n = 17) were significantly below (20%) normal females (n = 72) and males (n = 13) at most sites. In the osteoporotic patients, but not the renal patients, there was preferential osteopenia of the spine. Bone loss in all anatomical areas became evident after the menopause with an annual loss rate of about 0.7%.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Mazess RB,Peppler WW,Chesney RW,Lange TA,Lindgren U,Smith E Jrdoi
10.1007/BF02405287subject
Has Abstractpub_date
1984-01-01 00:00:00pages
8-13issue
1eissn
0171-967Xissn
1432-0827journal_volume
36pub_type
杂志文章abstract::Pyrolyzed scales, fin spines, and bone from the ray-finned bony fish Polypterus (Actinopterygii) showed two mineral phases on X-ray diffraction: hydroxyapatite (HA), Ca5(PO4)3OH, and whitlockite, Ca3(PO4)2. The ratio of HA/whitlockite varied with the structure (scale, spine, bone) within each individual fish. The rela...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02441216
更新日期:1979-08-24 00:00:00
abstract::Previous studies have indicated that children with inflammatory bowel disease (IBD) may not achieve optimal bone mass. We evaluated the skeletal characteristics in children and adolescents with IBD. This cross-sectional cohort study comprised 80 IBD patients (median age 14.9 years, range 5-20) with a median disease du...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9617-2
更新日期:2012-08-01 00:00:00
abstract::Calcaneus bone mineral density (BMD) of 738 Japanese women (605 healthy and 133 with osteoporosis) was measured using single X-ray absorptiometry (SXA). A reference range of calcaneus BMD values for healthy Japanese women was established and the usefulness of this method for screening and diagnosis of osteoporosis was...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900665
更新日期:1999-08-01 00:00:00
abstract::In this cross-sectional study, 91 healthy premenopausal women aged 20-39 years were investigated to determine the effect of physical activities during their teenage years on their current bone mineral densities (BMD). We measured whole-body BMD (WBMD), lumbar BMD (LBMD), and radial BMD (RBMD) with dual energy X-ray ab...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02684999
更新日期:2001-01-01 00:00:00
abstract::We treated four hypercalcemic cancer patients by nasal hCT, 3 x 2 mg daily, which has been reported to be active in Paget's disease at lower doses. Only one patient became normocalcemic and mean (+/- SEM) calcium levels fell from 11.6 +/- 0.2 mg/dl before therapy to 10.7 +/- 0.6 mg/dl 2-3 days after starting hCT. The ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00296210
更新日期:1992-07-01 00:00:00
abstract::Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However, questions still persist concerning the effect of these drugs on bone properties such as ultrastructure and quality, particularly in the growing patient. To addres...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010045
更新日期:2001-08-01 00:00:00
abstract::It has been suggested that oxidative stress is associated with the pathogenesis of osteoporosis. The objective of this study was to explore the association between a marker of oxidative stress and either bone turnover markers or bone mineral density (BMD) in postmenopausal women. In addition, the effects of oxidative ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-010-9393-9
更新日期:2010-09-01 00:00:00
abstract::The P2X7 nucleotide receptor (P2X7R) is an ATP-gated ion channel expressed in bone cells. Homozygous null P2X7R (P2X7R(-/-)) mice have reduced bone formation, so we hypothesized that P2X7R(-/-) mice have impaired fracture healing compared to P2X7R(+/+) control mice. To test the hypothesis, adult P2X7R(-/-) mice and P2...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-009-9237-7
更新日期:2009-05-01 00:00:00
abstract::Aluminum ions (Al) and chromium (III) ions (Cr), as they exist in aqueous solution at neutral pH, adsorb onto calcium hydroxyapatite crystals (HAP) and severely inhibit their dissolution process, when present in concentrations less than 1 microM. Iron (III) ions (Fe), at concentrations up to 10 microM, have no effect ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555127
更新日期:1987-07-01 00:00:00
abstract::During mechanical unloading, endothelial cells reduce osteogenesis and increase bone resorption. Here we describe the feedback response of endothelial cells to unloaded osteoblasts. Primary endothelial cells, ex vivo mouse aortic rings and chicken egg yolk membranes were incubated with conditioned medium from mouse pr...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-018-0496-z
更新日期:2019-03-01 00:00:00
abstract::As the correlation of bone mass from childhood to adulthood is unclear, we conducted a long-term prospective observational study to determine if a pediatric bone mass scan could predict adult bone mass. We measured cortical bone mineral content (BMC [g]), bone mineral density (BMD [g/cm(2)]), and bone width (cm) in th...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-013-9802-y
更新日期:2014-02-01 00:00:00
abstract::Cortical bone can be modeled as a complex hierarchical composite interrelating both structure and material properties on four levels of structural organization: molecular, ultrastructural, microscopic, and macroscopic. In young animals, the microstructural systems are long parallel lamellar units, plexiform bone, whic...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02406131
更新日期:1984-01-01 00:00:00
abstract::The aim of this work was to explore the reduction of fluoride concentrations in the skeleton after stopping experimental fluoride administration. Fluoride was administered to the rats at varying doses (0, 50, 100 ppm in drinking water) and for different lengths of time (4, 13, 25 weeks). A series of fluoride concentra...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00318049
更新日期:1995-04-01 00:00:00
abstract::Osteoarthritis (OA), the most prevalent chronic joint disease, increases in prevalence with age, and affects majority of individuals over the age of 65 and is a leading musculoskeletal cause of impaired mobility in the elderly. Because the precise molecular mechanisms which are involved in the degradation of cartilage...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-014-9917-9
更新日期:2014-12-01 00:00:00
abstract::Impact activity is an important contributor to bone accrual. Children engaging in such activity have been shown to have greater bone mineral density (BMD) than their peers. This cross-sectional study was designed to quantify the association between BMD and impact activity in pre-pubescent girls, specifically examining...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-001-1131-x
更新日期:2003-01-01 00:00:00
abstract::Carboxy-terminal pyridinoline cross-linked telopeptide of type I collagen (ICTP) in serum has recently been proposed as a new biochemical marker of bone resorption. In the present study we compared serum ICTP with radiopharmaceutical and histomorphometric measurements of bone turnover in postmenopausal women with mild...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章
doi:10.1007/BF00316286
更新日期:1994-01-01 00:00:00
abstract::We measured serum concentrations of bone Gla-protein (osteocalcin, BGP) and carboxyterminal propeptide of type I procollagen (PICP) in 14 patients with active acromegaly. Blood was collected at 0800 for measurement of bone Gla-protein (BGP), carboxyterminal propeptide of type I procollagen (PICP), and insulin-like gro...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00298716
更新日期:1993-03-01 00:00:00
abstract::The goal of this study was to find out if bone can recover after long-term administration of bisphosphonate. Disodium pamidronate (APD) was given orally by gavage to mature beagle dogs at doses of 0, 2.5, 12.5, and 25 mg/kg/day for 1 year (0.1% concentration) and the animals were allowed to recover for another year. A...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00310408
更新日期:1994-10-01 00:00:00
abstract::The aim of this study was to evaluate the association among phalangeal morphometric parameters, amplitude-dependent speed of sound (AD-SOS), ultrasound bone profile index (UBPI), and spinal bone mineral density (BMD) and fracture status. One hundred women (controls, mean age 53 +/- 12 years) and 40 osteoporotic women ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-001-1092-0
更新日期:2003-04-01 00:00:00
abstract::This study examined bone density among postmenopausal Buddhist nuns and female religious followers of Buddhism in southern Taiwan and related the measurements to subjects characteristics including age, body mass, physical activity, nutrient intake, and vegetarian practice. A total of 258 postmenopausal Taiwanese veget...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/pl00005812
更新日期:1997-03-01 00:00:00
abstract::To evaluate the associations of sarcopenia and previous falls with 2-year major osteoporotic fractures (MOFs) in community-dwelling older adults. Four thousand Chinese men and women ≥ 65 years recruited from Hong Kong communities were prospectively followed up. Measures of muscle mass, grip strength, gait speed and fa...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-020-00709-z
更新日期:2020-08-01 00:00:00
abstract::We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555980
更新日期:1990-09-01 00:00:00
abstract::The acute-phase response (APR) is frequently observed in patients treated with intravenous (iv) zoledronate (ZOL). We investigated whether a short course of rosuvastatin (ROSU) could attenuate the ZOL--induced APR through blocking the mevalonate pathway at a proximal level. Twenty-eight osteoporotic postmenopausal wom...
journal_title:Calcified tissue international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00223-011-9468-2
更新日期:2011-05-01 00:00:00
abstract::The effect of teriparatide treatment on microdamage accumulation has yet to be examined in animal studies. The purpose of this study was to investigate the effect of once-weekly teriparatide treatment on bone microdamage accumulation and the relationship between microdamage parameters and bone mass, architecture, turn...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-018-0500-7
更新日期:2019-04-01 00:00:00
abstract::Our knowledge of the developmental changes in the concentration of serum and bone osteocalcin (OC) is limited. To investigate the interrelationship between skeletal and circulatory OC during acquisition of peak bone density in mice, we examined the temporal changes in the concentration of serum and bone OC from 3 to 1...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-001-1106-y
更新日期:2002-11-01 00:00:00
abstract::The relationship between oral indicators and bone mineral density (BMD) has been studied by many investigators, with mixed and complex results. The purpose of the present cross-sectional study was to evaluate the associations of periodontal conditions and tooth loss with metacarpal BMD (m-BMD) in a community-based coh...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-004-0275-x
更新日期:2005-07-01 00:00:00
abstract::Conventional transmission electron microscopy requires an effective dehydration of the tissue specimens under investigation. This dehydration, for which ethanol most often is used, may influence the solubility of the slightly soluble calcium phosphates. To study the behavior of calcium phosphates in ethanol, stable ne...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02554840
更新日期:1985-03-01 00:00:00
abstract::The tumor-suppressor p53 is a transcription factor that regulates a number of genes in the process of cell-cycle inhibition, apoptosis, and DNA damage. Recent studies have revealed a crucial role for p53 in bone remodeling. In our previous studies we have shown that p53 is an important regulator of osteoblast differen...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-011-9533-x
更新日期:2011-11-01 00:00:00
abstract::The peptide hormone calcitonin is a potent inhibitor of osteoclastic resorption, but it is unstable and poorly absorbed following oral administration. Conjugates of salmon calcitonin covalently linked to low-molecular-weight amphiphilic polymers show improved stability and absorption. The purpose of this study was to ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-002-1051-4
更新日期:2003-09-01 00:00:00
abstract::The histologic heterogeneity of osteoporosis relative to normal controls has attracted great interest. There has been controversy as to whether patients with high turnover osteoporosis may convert to a normal or low turnover form, and vice versa. We have studied 44 patients over 12 years by dynamic histomorphometry an...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00675620
更新日期:1993-01-01 00:00:00