Osteocalcin gene expression is regulated by wild-type p53.

abstract：:Inorganic phosphate (P(i)) can regulate the level of skeletal alkaline phosphatase (ALP) activity in human osteoblast-like cells, but not by means of changes in transcription or release from the cell surface. The current studies were intended to determine whether (1) P(i) affected the inactivation of ALP activity in h...

journal_title：Calcified tissue international

authors： Farley JR

更新日期：1995-11-01 00:00:00

abstract：:The potassium pyroantimonate technique was utilized for the selective subcellular localization of calcium in the mandibular condylar cartilage of 1-day-old rats. Electron dense calcium pyroantimonate precipitates were localized principally in mitochondria and at the cell membrane of the chondrocytes. In addition, smal...

journal_title：Calcified tissue international

authors： Morris DC,Appleton J

更新日期：1980-01-01 00:00:00

abstract：:We have compared two components of bacterial cell walls, muramyl dipeptide (MDP) and lipopolysaccharide (LPS), for their effects on bone resorption as measured by the release of previously incorporated 45Ca. MDP is the smallest active component of peptidoglycan, whereas LPS is the active component of endotoxin. Fetal ...

journal_title：Calcified tissue international

authors： Raisz LG,Alander C,Eilon G,Whitehead SP,Nuki K

更新日期：1982-07-01 00:00:00

abstract：:Mandibular first molars of 17-day-old mouse embryos were cultured in vitro to examine the histological effects of various concentrations of parathyroid hormone (PTH) on odontogenesis of the molars. PTH did not affect the cytodifferentiation of mesenchymal cells into preodontoblasts but inhibited that of preodontoblast...

journal_title：Calcified tissue international

authors： Sakakura Y

更新日期：1987-01-01 00:00:00

abstract：:The effect of ascorbic acid deficiency on bone metabolism was evaluated using the ascorbate-requiring Osteogenic Disorder Shionogi (ODS) rat model. Ascorbic acid (Asc)-deficient rats gained body weight in a manner similar to Asc-supplemented rats (control) during 3 weeks, but began to lose weight during the 4th week o...

journal_title：Calcified tissue international

authors： Goto A,Tsukamoto I

更新日期：2003-08-01 00:00:00

abstract：:Further insight into human tooth enamel, dense fraction (TE), has been obtained by following the change and loss of CO3(2-), OH-, structurally incorporated H2O, Cl-, and, indirectly, HPO4(2-) after TE had been heated in N2 or vacuum in the range 25-1000 degrees C. Quantitative infrared spectroscopic, lattice parameter...

journal_title：Calcified tissue international

authors： Holcomb DW,Young RA

更新日期：1980-01-01 00:00:00

abstract：:Primary cilia are responsible for sensing mechanical loading in osteocytes. However, the underlying working mechanism of cilia remains elusive. An osteocyte model is necessary to reveal the role of cilia. Furthermore, the osteocyte model should be with upregulated or downregulated primary cilium expression. Herein, we...

journal_title：Calcified tissue international

authors： Ding D,Yang X,Luan HQ,Wu XT,He C,Sun LW,Fan YB

更新日期：2020-12-01 00:00:00

abstract：:Bone is a dynamic tissue that is able to sense and adapt to mechanical stimuli by modulating its mass, geometry, and structure. Bone marrow stromal cells (BMSCs) are known to play an integral part in bone formation by providing an osteoprogenitor cell source capable of differentiating into mature osteoblasts in respon...

journal_title：Calcified tissue international

authors： Mauney JR,Sjostorm S,Blumberg J,Horan R,O'Leary JP,Vunjak-Novakovic G,Volloch V,Kaplan DL

更新日期：2004-05-01 00:00:00

abstract：:Men and women (n = 518) receiving moderate-to-high doses of corticosteroids were enrolled in two studies with similar protocols and randomly assigned to receive either placebo or risedronate (2.5 or 5 mg) for 1 year. All patients received daily calcium supplementation (500-1000 mg), and most also received supplemental...

journal_title：Calcified tissue international

authors： Wallach S,Cohen S,Reid DM,Hughes RA,Hosking DJ,Laan RF,Doherty SM,Maricic M,Rosen C,Brown J,Barton I,Chines AA

更新日期：2000-10-01 00:00:00

abstract：:We describe here the activity of a novel selective estrogen receptor modulator, SP500263. When given to adult ovariectomized (OVX) rats for 28 days at doses of 0.3, 1, or 3 mg/kg/day, we found that SP500263 partially protected against OVX-induced loss of bone mineral content in the distal ends of femurs and in the who...

journal_title：Calcified tissue international

authors： Sutherland MK,Brady H,Gayo-Fung LM,Leisten J,Lipps SG,McKie JA,O'Leary E,Patnaik N,Anderson DW,Bhagwat SS,Stein B

更新日期：2003-06-01 00:00:00

abstract：:High serum levels of IGFBP-1 are related both to low body mass index (BMI) and to low insulin-like growth factor 1 (IGF-I), which both in turn are related to low bone mineral density (BMD) and to increased fracture risk. However, we have found no previous prospective studies on IGFBP-1 and fracture risk. Despite its n...

journal_title：Calcified tissue international

authors： Lundin H,Sääf M,Strender LE,Nyren S,Johansson SE,Salminen H

更新日期：2016-10-01 00:00:00

abstract：:We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...

journal_title：Calcified tissue international

authors： Epstein S,Schlosberg M,Fallon M,Thomas S,Movsowitz C,Ismail F

更新日期：1990-09-01 00:00:00

abstract：:Bruck syndrome is a rare autosomal recessive form of osteogenesis imperfecta (OI), which is mainly characterized by joint contractures and recurrent fragility fractures. Mutations in FKBP10 and PLOD2 were identified as the underlying genetic defects of Bruck syndrome. Here we investigated the phenotypes and the pathog...

journal_title：Calcified tissue international

authors： Lv F,Xu X,Song Y,Li L,Asan,Wang J,Yang H,Wang O,Jiang Y,Xia W,Xing X,Li M

更新日期：2018-03-01 00:00:00

abstract：:A resolution-enhanced Fourier Transform Infrared (FTIR) Spectroscopic study of the CO3(2-) ion in pig enamel of increasing age and maturity has demonstrated the existence of four different, main carbonate locations. The major CO3(2-) site arises as a result of the substitution of CO3(2-) ions in the positions occupied...

journal_title：Calcified tissue international

authors： Rey C,Renugopalakrishnan V,Shimizu M,Collins B,Glimcher MJ

更新日期：1991-10-01 00:00:00

abstract：:To test the hypothesis that the relationship between fat mass (FM) and bone mineral density (BMD) is mediated by leptin. The study involved 611 individuals aged 20-89 years who were randomly sampled from Ho Chi Minh City (Vietnam). BMD at the femoral neck (FN), lumbar spine (LS), and whole body (WB) was measured by DX...

journal_title：Calcified tissue international

authors： Ho-Pham LT,Lai TQ,Nguyen UD,Bui QV,Nguyen TV

更新日期：2017-01-01 00:00:00

abstract：:The metacarpal bone mineral density (BMD) and metacarpal index (MCI) of the second metacarpal bone were measured by computed X-ray densitometry (CXD) (Teijin Ltd., Tokyo), which we have established with the development of microdensitometry of radiographs. In this study, we evaluated the basic attributes of this CXD me...

journal_title：Calcified tissue international

authors： Matsumoto C,Kushida K,Yamazaki K,Imose K,Inoue T

更新日期：1994-11-01 00:00:00

abstract：:Familial hypocalciuric hypercalcemia (FHH) is often considered in the differential diagnosis of hyperparathyroidism, but is rarely diagnosed. So far, FHH has not been documented in Israel. This report presents preliminary evidence for the occurrence of FHH in Israel. ...

journal_title：Calcified tissue international

authors： Liel Y,Arie R,Vered I

更新日期：1997-07-01 00:00:00

abstract：:Parameters of mineral metabolism were examined in 6 patients with moderately severe anticonvulsant drug-induced osteomalacia. Compared to 15 matched controls, the patients exhibited significantly reduced serum calcium, inorganic phosphate, and 25-hydroxyvitamin D concentration, elevated serum alkaline phosphatase and ...

journal_title：Calcified tissue international

authors： Hahn TJ,Halstead LR

更新日期：1979-03-13 00:00:00

abstract：:To clarify the mechanisms underlying shockwave-induced osteogenesis, we applied shockwave to rat femoral shafts from the ventral side. We assessed bone mineral content (BMC) and bone mineral density (BMD), and analyzed the spatial and temporal gene expression for pro-alpha1 (I) collagen (COL1A1), pro-alpha1 (II) colla...

journal_title：Calcified tissue international

authors： Takahashi K,Yamazaki M,Saisu T,Nakajima A,Shimizu S,Mitsuhashi S,Moriya H

更新日期：2004-02-01 00:00:00

abstract：:A strategy based on high pressure liquid chromatography (HPLC) techniques for the isolation or a principal amelogenin molecule from a single human dentition is described. A partial sequence (33 residues) for this 24 kDa amelogenin is presented and related to earlier studies of human 5 kDa tyrosine-rich amelogenin poly...

journal_title：Calcified tissue international

authors： Fincham AG,Hu YY,Lau E,Pavlova Z,Slavkin HC,Snead ML

更新日期：1990-08-01 00:00:00

abstract：:Bone tissue is a source of growth factors; among them, insulinlike growth factor I (IGF-I) is probably an important local regulator of bone formation. This study has been carried out in order to assess the effects of natural menopause on plasma concentrations of IGF-I in the first 6 years after the cessation of gonada...

journal_title：Calcified tissue international

authors： Romagnoli E,Minisola S,Carnevale V,Scarda A,Rosso R,Scarnecchia L,Pacitti MT,Mazzuoli G

更新日期：1993-07-01 00:00:00

abstract：:Bone involvement, mainly osteoporosis but also osteosclerosis, is frequent in patients with indolent systemic mastocytosis (ISM). The recent characterization of the canonical Wnt/β-catenin pathway in the regulation of bone remodeling provided important insights for our understanding of the pathophysiology of a number ...

journal_title：Calcified tissue international

authors： Rossini M,Viapiana O,Zanotti R,Tripi G,Perbellini O,Idolazzi L,Bonifacio M,Adami S,Gatti D

更新日期：2015-05-01 00:00:00

abstract：:We assessed the relationship of bone density and microarchitecture between hand, peripheral, and axial skeletal sites using high-resolution peripheral quantitative computed tomography (HR-pQCT) and dual-energy X-ray absorptiometry (DXA) in patients with rheumatoid arthritis (RA) and which factors influence these param...

journal_title：Calcified tissue international

authors： Zhu TY,Griffith JF,Qin L,Hung VW,Fong TN,Kwok AW,Leung PC,Li EK,Tam LS

更新日期：2012-11-01 00:00:00

abstract：:The purpose of this study was to (1) quantify the healing process of the human osteoporotic proximal humerus fracture (PHF) expressed in terms of callus formation over the fracture region using BMD scanning, and (2) quantify the impact of medical intervention with vitamin D3 and calcium on the healing process of the h...

journal_title：Calcified tissue international

authors： Doetsch AM,Faber J,Lynnerup N,Wätjen I,Bliddal H,Danneskiold-Samsøe B

更新日期：2004-09-01 00:00:00

abstract：:Increased bone loss has been noted in lymphoma patients; however, the incidence of hip fracture is not known. The aim of our study was to explore the risk for hip fracture in patients with lymphoma compared with the entire Swedish population. The risk of hip fracture was determined in a retrospective population cohort...

journal_title：Calcified tissue international

authors： Johansson P,Lind Kristjansdottir H,Johansson H,Jakir A,Mellström D,Lewerin C

更新日期：2020-06-01 00:00:00

abstract：:Inoculation of Moloney murine sarcoma virus (M-MSV) into shank muscles of adult NMRI mice resulted in localized sarcoma and periosteal membrane proliferation with subsequent periosteal bone formation. Newly formed bone arose from outer surface of shank bones. Two weeks after M-MSV inoculation the width of bone cortex ...

journal_title：Calcified tissue international

authors： Włodarski K,Kobus M,Luczak M,Dołowy J

更新日期：1981-01-01 00:00:00

abstract：:Normative bone mineral density (BMD) and bone mineral content (BMC) values for the total body (TB), proximal femur (PF), and antero-posterior lumbar spine (LS) were obtained from a large cross-sectional sample of children and adolescents who were 8-17 years of age. There were 977 scans for the TB, 892 for the PF, and ...

journal_title：Calcified tissue international

authors： Faulkner RA,Bailey DA,Drinkwater DT,McKay HA,Arnold C,Wilkinson AA

更新日期：1996-11-01 00:00:00

abstract：:Studies suggest that long-term use of proton pump inhibitors (PPIs) may be associated with an increased risk of fracture. However, the role of medication adherence in this association is not fully understood. A retrospective cohort study was conducted to examine the relationship between PPI use/adherence and fracture ...

journal_title：Calcified tissue international

authors： Ding J,Heller DA,Ahern FM,Brown TV

更新日期：2014-06-01 00:00:00

abstract：:Regular tennis play is associated with impressive asymmetries in bone strength in favor of the racquet arm, particularly in the humerus. However, the relative effects of service and ground strokes are not known. Serendipitously, we encountered a 46-year-old regular tennis player who has played service and ground strok...

journal_title：Calcified tissue international

authors： Ireland A,Degens H,Maffulli N,Rittweger J

更新日期：2015-08-01 00:00:00

abstract：:Fracture healing is a natural process that recapitulates embryonic skeletal development. In the early phase after fracture, reactive oxygen species (ROS) are produced under inflammatory and ischemic conditions due to vessel injury and soft tissue damage, leading to cell death. Usually, such damage during the course of...

journal_title：Calcified tissue international

authors： Kubo Y,Wruck CJ,Fragoulis A,Drescher W,Pape HC,Lichte P,Fischer H,Tohidnezhad M,Hildebrand F,Pufe T,Jahr H

更新日期：2019-10-01 00:00:00