Abstract:
:A strategy based on high pressure liquid chromatography (HPLC) techniques for the isolation or a principal amelogenin molecule from a single human dentition is described. A partial sequence (33 residues) for this 24 kDa amelogenin is presented and related to earlier studies of human 5 kDa tyrosine-rich amelogenin polypeptides (TRAPs). A failure to identify amino acid residue #25 (tryptophan in other amelogenins) suggests that this 24 kDa amelogenin is the progenitor of the human TRAP-2 molecule and provides further support for the possibility of several human amelogenin gene products, generated by splice-junction selection, from the single amelogenin gene in the same individual. Alternatively, multiple amelogenins may arise by expression of both the AMELX and AMELY loci.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Fincham AG,Hu YY,Lau E,Pavlova Z,Slavkin HC,Snead MLdoi
10.1007/BF02555993subject
Has Abstractpub_date
1990-08-01 00:00:00pages
105-11issue
2eissn
0171-967Xissn
1432-0827journal_volume
47pub_type
杂志文章abstract::Test implant plates surgically retrieved from distal femurs of dogs were studied by Raman spectroscopy in order to characterize the bone-implant interface. The implant surface consisted of phosphate mineral, plasma sprayed on a titanium substrate. On the basis of its spectroscopic signature, the phosphate mineral of b...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556157
更新日期:1991-05-01 00:00:00
abstract::Regular exercise and physical activity (PA) are known to be protective factors for maintaining bone mineral density (BMD) and preventing osteoporotic fracture. We investigated the associations between leisure-time PA and BMD in 2,903 premenopausal and 2,267 postmenopausal women in Korea. BMDs of the lumbar spine and f...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9624-3
更新日期:2012-09-01 00:00:00
abstract::Further insight into human tooth enamel, dense fraction (TE), has been obtained by following the change and loss of CO3(2-), OH-, structurally incorporated H2O, Cl-, and, indirectly, HPO4(2-) after TE had been heated in N2 or vacuum in the range 25-1000 degrees C. Quantitative infrared spectroscopic, lattice parameter...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02407181
更新日期:1980-01-01 00:00:00
abstract::A whole-body counter was used to measure the retention and distribution of radioactivity along the longitudinal axis of the body during 10 days after the intravenous injection of 50 microCi of 47Ca. These data and the simultaneous measurements of the serum specific activity allowed us to calculate, by the Bauer-Carlss...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405001
更新日期:1983-01-01 00:00:00
abstract::The orientation of nanoscale mineral platelets was quantitatively evaluated in relation to the shape of lacunae associated with partially embedded osteocytes (osteoblastic-osteocytes) on the surface of deproteinised trabecular bone of adult sheep. By scanning electron microscopy and image analysis, the mean orientatio...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-015-0072-8
更新日期:2016-02-01 00:00:00
abstract::Glucocorticoid-induced osteoporosis has been reported to be caused by enhanced bone resorption and suppressed bone formation. To clarify whether administration of vitamin K, which enhances bone formation, prevents prednisolone-induced loss of bone mineral density (BMD), a randomized, prospective, controlled study was ...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/pl00005832
更新日期:2000-02-01 00:00:00
abstract::The purpose of this study was to determine the efficacy of using bone mineral measurements of the calcaneus to evaluate osteoporosis. Dual energy X-ray absorptiometry (DXA) of the calcaneus was compared with posteroanterior lumbar absorptiometry (DXA) and vertebral quantitative computed tomography (QCT) measurements i...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00298738
更新日期:1995-01-01 00:00:00
abstract::There is increasing interest in identifying new pathways and candidate genes that confer susceptibility to osteoporosis. There is evidence that adipogenesis and osteogenesis may be related, including a common bone marrow progenitor cell for both adipocytes and osteoblasts. Perilipin 1 (PLIN1) and Perilipin 4 (PLIN4) a...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-011-9552-7
更新日期:2012-02-01 00:00:00
abstract::The extractions of 85Sr2+, 18F-, sucrose-14C, EDTA-51Cr, and antipyrine-14C in bone were determined by the multiple indicator-dilution method. Fluoride and strontium extractions were 18 to 70% during a single transcapillary passage, and those of EDTA and sucrose were from 11 to 59%, whereas extraction of antipyrine wa...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02407178
更新日期:1980-01-01 00:00:00
abstract::The goal of this study was to find out if bone can recover after long-term administration of bisphosphonate. Disodium pamidronate (APD) was given orally by gavage to mature beagle dogs at doses of 0, 2.5, 12.5, and 25 mg/kg/day for 1 year (0.1% concentration) and the animals were allowed to recover for another year. A...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00310408
更新日期:1994-10-01 00:00:00
abstract::The purpose of this study was to (1) quantify the healing process of the human osteoporotic proximal humerus fracture (PHF) expressed in terms of callus formation over the fracture region using BMD scanning, and (2) quantify the impact of medical intervention with vitamin D3 and calcium on the healing process of the h...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00223-004-0167-0
更新日期:2004-09-01 00:00:00
abstract::The perilacunar areas of low mineral density in microradiographs from cortical bone of patients with hypophosphatemic (vitamin D-resistant) rickets are not evenly distributed throughout the bone tissue. Their frequency and distribution were determined in bone from 9 patients with this disease. It was found that the le...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02441169
更新日期:1979-04-17 00:00:00
abstract::The effects of 5, 10, and 20% dietary xylitol supplementations on the resorption of bone were studied. The resorption was measured by the urinary excretion of [3H] radioactivity from [3H]tetracycline-prelabeled rats. The 10 and 20% oral xylitol administrations caused a significant decrease in the excretion of [3H] as ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00298616
更新日期:1995-03-01 00:00:00
abstract::The aim of our study was to compare the results provided by the measurement of vertebral and femoral bone mineral density (BMD) for assessing the individual risk of osteoporosis as defined by either low BMD and/or rapid bone loss. Vertebral and femoral BMD were measured twice at a mean interval of 21 months in 85 norm...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00310196
更新日期:1993-05-01 00:00:00
abstract::Differences in trabecular and cortical bone loss have been demonstrated clinically, but differences in bone loss at different skeletal sites remain unclear. We examined regional variations in bone loss histomorphometrically in two strains of mice in which osteopenia progresses spontaneously: tiptoe-walking Yoshimura (...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900455
更新日期:1998-05-01 00:00:00
abstract::Patients with systemic lupus erythematosus (SLE), a chronic inflammatory disease characterized by loss of T- and B-cell tolerance to autoantigens, are at increased risk for osteoporosis and fractures. Mice deficient in Fc gamma receptor IIb (FcγRIIB) exhibit spontaneous SLE and its restoration rescues the disease. To ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-018-0464-7
更新日期:2018-12-01 00:00:00
abstract::We investigated the effects of conjugated estrogens as an add-back replacement drug, incadronate sodium as a bisphosphonate, and alfacalcidol as a vitamin D(3) analog on femoral bone mineral density (BMD) and bone mineral content (BMC) in female rats chronically treated with the gonadotropin-releasing hormone (GnRH) a...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900675
更新日期:1999-08-01 00:00:00
abstract::Twenty boys were followed during their puberty for about 2 years with examinations every third month. At each examination we determined serum concentrations of 25OHD3, 1,25(OH)2D3, 24,25(OH)2D3, 25.26(OH)2D3, alkaline phosphatase (AP) and testosterone together with bone mineral content (BMC) at the distal forearm. Hig...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556871
更新日期:1986-03-01 00:00:00
abstract::Normative bone mineral density (BMD) and bone mineral content (BMC) values for the total body (TB), proximal femur (PF), and antero-posterior lumbar spine (LS) were obtained from a large cross-sectional sample of children and adolescents who were 8-17 years of age. There were 977 scans for the TB, 892 for the PF, and ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900138
更新日期:1996-11-01 00:00:00
abstract::Dual photon absorptiometry (DPA) is currently the most widely used method for noninvasive bone mineral density (BMD) measurement of the axial skeleton. Dual energy X-ray absorptiometry (DEXA) is a recently developed technique that uses an X-ray tube as a photon source; it has demonstrated several significant advantage...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556250
更新日期:1991-11-01 00:00:00
abstract::We assessed the bone mineral density (BMD) of 16 matched sets of cadaveric proximal femurs and feet using dual-energy x-ray absorptiometry (DXA). We also estimated the femoral neck length from the DXA scans. Quantitative ultrasound densitometry was used to measure the velocity of sound and broadband ultrasound attenua...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00296338
更新日期:1995-02-01 00:00:00
abstract::Recommendations from the FNIH Sarcopenia Project are that appendicular lean mass (ALM, kg) adjusted for body mass index (BMI, kg/m2) be used for identifying low lean mass, with ALM/BMI cutpoints of < 0.789 m2 for men and < 0.512 m2 for women. We report normative ALM/BMI values for Australian adults, and compare the pe...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-018-0506-1
更新日期:2019-04-01 00:00:00
abstract::This study investigated whether bone turnover influences the response to alendronate in women with postmenopausal osteoporosis. One hundred postmenopausal osteoporotic women were randomized to receive either alendronate (10 mg/day) plus calcium (1000 mg/day) (n = 50) or calcium alone (n = 50). Vertebral and radial bon...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002239900713
更新日期:1999-11-01 00:00:00
abstract::We compared the effects of four vitamin D metabolites, 1 alpha,25 dihydroxy vitamin D3 (1 alpha,25(OH)2D3), 1 alpha hydroxy vitamin D3 (1 alpha OH D3), 25 hydroxy vitamin D3 (25 OH D3), and 24R,25 dihydroxy vitamin D (24R,25(OH)sD3) on resorption and collagen synthesis in fetal rat bone maintained in organ culture. Re...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02408532
更新日期:1980-01-01 00:00:00
abstract::Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However, questions still persist concerning the effect of these drugs on bone properties such as ultrastructure and quality, particularly in the growing patient. To addres...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010045
更新日期:2001-08-01 00:00:00
abstract::The effects of long-term running were studied in 20 beagle dogs. Ten dogs ran from the age of 15 weeks to the age of 70 weeks in a progressive program for up to 40 km/day. Ten sister dogs spent the same time in individual cages. At the age of 70 weeks the spines of the dogs were studied with regard to mineral density ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555099
更新日期:1991-01-01 00:00:00
abstract::Several studies have shown an association between circulating leptin concentration and bone mineral density. but most studies are cross-sectional in design and report findings in women only. We per-formed a population-based longitudinal study relating baseline plasma leptin concentration to bone mass at the lumbar spi...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-002-0017-x
更新日期:2004-05-01 00:00:00
abstract::Bone formation in a variety of contexts depends on angiogenesis; however, there are few reports of the vascular response to osteogenic skeletal loading. We used the rat forelimb compression model to characterize vascular changes after fatigue loading. The right forelimbs of 72 adult rats were loaded cyclically in vivo...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-007-9031-3
更新日期:2007-06-01 00:00:00
abstract::Osteoclastic bone resorption can be induced within the auditory bulla of the Mongolian gerbil by minute increases in air pressure. The objective of this study was to determine the rate at which osteoclasts are induced in areas of resorption and to compare the rate of osteoblast recruitment. Stainless steel tubes were ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556026
更新日期:1989-11-01 00:00:00
abstract::There is considerable interest in determining whether hypergravity can be used as a countermeasure for microgravity-induced bone loss. This study was conducted on 20 immature male rats in order to investigate possible elastic adaptations of cortical bone in rapidly growing rats exposed to chronic hypergravity. Ten rat...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900111
更新日期:1996-09-01 00:00:00