Opposing changes in osteocalcin levels in bone vs serum during the acquisition of peak bone density in C3H/HeJ and C57BL/6J mice.

abstract：:Carboxy-terminal pyridinoline cross-linked telopeptide of type I collagen (ICTP) in serum has recently been proposed as a new biochemical marker of bone resorption. In the present study we compared serum ICTP with radiopharmaceutical and histomorphometric measurements of bone turnover in postmenopausal women with mild...

journal_title：Calcified tissue international

authors： Hassager C,Jensen LT,Pødenphant J,Thomsen K,Christiansen C

更新日期：1994-01-01 00:00:00

abstract：:Parathyroid Hormone (PTH) stimulates calcium entry into bone cells in vitro, and this effect has been proposed to mediate the actions of PTH on bone. Using cells harvested from infant rat calvaria by collagenase digestion, we evaluated the sensitivity and specificity of this phenomenon. Calcium uptake was temperature ...

journal_title：Calcified tissue international

authors： Marcus R,Orner FB

更新日期：1980-01-01 00:00:00

abstract：:Studies of the effect of parathyroidectomy (PTX) on bone turnover in patients with the combination of primary hyperparathyroidism (PHPT) and Paget's disease (PD) are largely limited to case reports. The etiology of the combination is disputed. We report 30 patients and their biochemical (n = 17) and histomorphometric ...

journal_title：Calcified tissue international

authors： Gutteridge DH,Gruber HE,Kermode DG,Worth GK

更新日期：1999-12-01 00:00:00

abstract：:Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However, questions still persist concerning the effect of these drugs on bone properties such as ultrastructure and quality, particularly in the growing patient. To addres...

journal_title：Calcified tissue international

authors： Camacho NP,Raggio CL,Doty SB,Root L,Zraick V,Ilg WA,Toledano TR,Boskey AL

更新日期：2001-08-01 00:00:00

abstract：:Each of the presently available noninvasive methods used to determine the nature and degree of changes in skeletal mass has significant advantages and limitations. Dual photon absorptiometric techniques generally have a very low radiation dose. They are also less expensive to construct than other systems. However, the...

journal_title：Calcified tissue international

authors： Cohn SH

更新日期：1982-09-01 00:00:00

abstract：:Results of previous studies suggest that children and adolescents with osteogenesis imperfecta (OI) type IV have muscle force deficits. However, muscle function remains to be objectively quantified in this population. This study aimed to assess upper and lower extremity muscle function in patients with OI type IV. It ...

journal_title：Calcified tissue international

authors： Veilleux LN,Darsaklis VB,Montpetit K,Glorieux FH,Rauch F

更新日期：2017-10-01 00:00:00

abstract：:Syndesmophyte occurrence and axial bone loss were investigated in the heterozygous Tg187 tumor necrosis factor (TNF) transgenic mouse model (Tg-huTNF) of arthritis. Female and male Tg-huTNF mice were compared to wild-type mice (WT) at 2, 4, 6, 8, and 10 weeks. Syndesmophytes, intervertebral disc space, osteoclasts, os...

journal_title：Calcified tissue international

authors： Courbon G,Flammier S,Laroche N,Vico L,Marotte H,Coury F

更新日期：2017-06-01 00:00:00

abstract：:The influence of body mass index (BMI) on T scores for total body bone mineral content (TBBMC) and regional bone mineral content (RBMC) was studied in 186 healthy women: 100 postmenopausal, 35 perimenopausal, and 51 premenopausal. The three groups were divided by BMI >25 kg/m2 and BMI <25 kg/m2 and the postmenopausal ...

journal_title：Calcified tissue international

authors： Revilla M,Villa LF,Sánchez-Atrio A,Hernández ER,Rico H

更新日期：1997-08-01 00:00:00

abstract：:The effect of the degree of carboxylation of osteocalcin (OC) on the properties of bone is unclear. The aim of this study was to relate serum concentrations of total OC (tOC) and undercarboxylated OC (ucOC), measured with a two-site immunoassay, to bone mineral density (BMD) at the femoral neck and ultrasonic transmit...

journal_title：Calcified tissue international

authors： Liu G,Peacock M

更新日期：1998-04-01 00:00:00

abstract：:We studied the most complete skeletons found in an excavation from the 14th and 15th century in central Stockholm. One hundred eighty-seven were from men and 156 from women: 241 individuals were estimated to be between 20 and 39 and 102 between 40 and 59 years old at death. We examined the bones radiographically and b...

journal_title：Calcified tissue international

authors： Ekenman I,Eriksson SA,Lindgren JU

更新日期：1995-05-01 00:00:00

abstract：:Osteoclasts are large, multinucleated, terminally differentiated cells formed by the fusion of mononuclear hemopoietic precursors. Their function is the resorption of bone, which is an essential part of the growth, modeling and remodeling of the skeleton. Though some osteoclast differentiation factors have recently be...

journal_title：Calcified tissue international

authors： Gartland A,Buckley KA,Bowler WB,Gallagher JA

更新日期：2003-10-01 00:00:00

abstract：:Bone turnover markers (BTMs) are widely used for the management of osteoporosis, and the premenopausal reference range is the target value for the treatment of postmenopausal osteoporosis with antiresorbing agents. Three serum BTMs (serum C-telopeptide of type I collagen [CTX], osteocalcin [OC], and N-terminal propept...

journal_title：Calcified tissue international

authors： Adami S,Bianchi G,Brandi ML,Giannini S,Ortolani S,DiMunno O,Frediani B,Rossini M,BONTURNO study group.

更新日期：2008-05-01 00:00:00

abstract：:Long-term use of hydrochlorothiazide (HCTZ), a common diuretic agent for hypertension, has been associated with increased bone density and reduced hip fracture rates in patients. In this study, we sought to examine whether HCTZ has an anabolic effect on the proliferation of human osteoblasts (derived from either verte...

journal_title：Calcified tissue international

authors： Lau KH,Song XD,Ochi M,Wergedal JE

更新日期：1996-12-01 00:00:00

abstract：:Normal rat bone maturation has been studied using biochemical methods and hydrazine separation of matrix and mineral for X-ray diffraction. In the bone, the amount of mineral increases between 4 and 22 weeks of age, while in the matrix, the ratio of noncollagenous protein to collagen progressively decreases. In minera...

journal_title：Calcified tissue international

authors： Burnell JM,Teubner EJ,Miller AG

更新日期：1980-01-01 00:00:00

abstract：:The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...

journal_title：Calcified tissue international

authors： Heervä E,Leinonen P,Kuorilehto T,Peltonen S,Pöyhönen M,Väänänen K,Peltonen J

更新日期：2013-01-01 00:00:00

abstract：:Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius...

journal_title：Calcified tissue international

authors： Nijs J,Van Essche E,De Munck M,Dequeker J

更新日期：2000-07-01 00:00:00

abstract：:Racial differences in bone mineral density (BMD) appear to account in part for racial differences in the incidence of osteoporosis and fractures. We previously reported that the greater BMD in adult blacks compared with whites is associated with a higher serum 17 beta-estradiol and greater secretion of growth hormone ...

journal_title：Calcified tissue international

authors： Wright NM,Papadea N,Veldhuis JD,Bell NH

更新日期：2002-03-01 00:00:00

abstract：:There are few longitudinal data on change in bone structure and muscle mass, strength and function in later life. We report these, and consider bone-muscle interrelationships in older men and women. We studied 188 men and 166 women from the Hertfordshire Cohort Study, who underwent peripheral quantitative computed tom...

journal_title：Calcified tissue international

authors： Patel A,Edwards MH,Jameson KA,Ward KA,Fuggle N,Cooper C,Dennison EM

更新日期：2018-11-01 00:00:00

abstract：:Molybdenum (Mo), at high concentrations, induces changes in the epiphyseal growth plate through its effects on copper (Cu) metabolism but it is unclear whether or not Mo can induce changes independent of its effects on copper status. To this end, the effect of Mo on longitudinal bone growth was examined in rats. Dieta...

journal_title：Calcified tissue international

authors： Parry NM,Phillippo M,Reid MD,McGaw BA,Flint DJ,Loveridge N

更新日期：1993-09-01 00:00:00

abstract：:We examined differences in patients' survival after hip fracture (HF) and risk for subsequent HF among patients treated with oral and intravenous bisphosphonates (oBPs, iBPs), denosumab (DMAB), and patients without therapy. We used data from all patients in Austria aged ≥ 50 who sustained a HF between 2012 and 2017 an...

journal_title：Calcified tissue international

authors： Behanova M,Reichardt B,Stamm TA,Zwerina J,Klaushofer K,Kocijan R

更新日期：2019-12-01 00:00:00

abstract：:Quantitative computed tomography (QCT) was compared to dual X-ray absorptiometry (DXA) measured in the lumbar spine of 508 European women defined as normal without fracture (NoF), or osteoporotic (OP), with either vertebral fracture (VF), or peripheral fracture (PF). The correlations between QCT and DXA BMD measuremen...

journal_title：Calcified tissue international

authors： Bergot C,Laval-Jeantet AM,Hutchinson K,Dautraix I,Caulin F,Genant HK

更新日期：2001-02-01 00:00:00

abstract：:The gut microbiota (GM) is the whole of commensal, symbiotic, and pathogenic microorganisms living in our intestine. The GM-host interactions contribute to the maturation of the host immune system, modulating its systemic response. It is well documented that GM can interact with non-enteral cells such as immune cells,...

journal_title：Calcified tissue international

authors： D'Amelio P,Sassi F

更新日期：2018-04-01 00:00:00

abstract：:Conventional glucocorticoids exert a negative influence on calcium balance, and long-term treatment with these agents leads to osteopenia. Deflazacort is an oxazoline derivative of prednisolone with documented calcium-sparing properties when compared to prednisone on a weight basis. The purpose of the present study wa...

journal_title：Calcified tissue international

authors： Lund B,Egsmose C,Jørgensen S,Krogsgaard MR

更新日期：1987-12-01 00:00:00

abstract：:Tumor tissue from a patient with squamous cell carcinoma of the lung and hypercalcemia has been serially implanted into athymic mice. Tumor-bearing mice develop cachexia, hypercalcemia without bone metastases, hypophosphatemia, increased urinary cyclic adenosine monophosphate (cAMP) to creatinine ratio, and undetectab...

journal_title：Calcified tissue international

authors： Abramson EC,Kukla LJ,Shevrin DH,Lad TE,McGuire WP,Kukreja SC

更新日期：1984-09-01 00:00:00

abstract：:The mineral in bone is located primarily within the collagen fibril, and during mineralization the fibril is formed first and then water within the fibril is replaced with mineral. Our goal is to understand the mechanism of fibril mineralization, and as a first step we recently determined the size exclusion characteri...

journal_title：Calcified tissue international

authors： Toroian D,Price PA

更新日期：2008-02-01 00:00:00

abstract：:The effect of the configuration of porous cylindrical hydroxyapatite (HA) scaffold and laminin preparation of the scaffold on bone formation was estimated. HA scaffolds with a hollow center of 2 or 4 mm in diameter and those without a hollow center were used. The scaffolds were immersed in laminin solution or in cultu...

journal_title：Calcified tissue international

authors： Yoshikawa M,Tsuji N,Shimomura Y,Hayashi H,Ohgushi H

更新日期：2008-08-01 00:00:00

abstract：:Experimental analysis with paired femurs provides the opportunity to study within-person differences in fracture type and associated structural side differences. We hypothesized that different fracture types in the hips of a subject are associated with structural asymmetry. Bone mineral density (BMD) and structural me...

journal_title：Calcified tissue international

authors： Thevenot J,Pulkkinen P,Kuhn V,Eckstein F,Jämsä T

更新日期：2010-09-01 00:00:00

abstract：:Compressive strength index (CSI) of the femoral neck is a parameter that integrates the information of bone mineral density (BMD), femoral neck width (FNW), and body weight. CSI is considered to have the potential to improve the performance of assessment for hip fracture risk. However, studies on CSI have been rare. I...

journal_title：Calcified tissue international

authors： Yu N,Liu YJ,Pei Y,Zhang L,Lei S,Kothari NR,Li DY,Papasian CJ,Hamilton J,Cai JQ,Deng HW

更新日期：2010-10-01 00:00:00

abstract：:The purpose of this study was to estimate clinical validity of a new available immunoradiometric assay for circulating intact human BGP (N-tact Osteo SP) by measuring this protein in a large number of normal subjects and patients with the most common metabolic bone diseases. One hundred normal subjects were studied in...

journal_title：Calcified tissue international

authors： Minisola S,Pacitti MT,Romagnoli E,Rosso R,Carnevale V,Caravella P,Scillitani A,Dicembrino F

更新日期：1999-05-01 00:00:00

abstract：:The purpose of this study was to ascertain whether biochemical markers of bone turnover predict bone loss. The survey was carried out in Taiji, Wakayama Prefecture, Japan. From a list of inhabitants aged 40-79 years, 400 participants (50 men and 50 women in each of four age groups) were selected randomly. Bone mineral...

journal_title：Calcified tissue international

authors： Yoshimura N,Hashimoto T,Sakata K,Morioka S,Kasamatsu T,Cooper C

更新日期：1999-09-01 00:00:00