Muscle Function in Osteogenesis Imperfecta Type IV.

abstract：:Osteoarthritis (OA) is a chronic, debilitating disease affecting millions of people worldwide. Management of OA involves pharmacological and non-pharmacological approaches. Conventional pharmacological treatments have limited efficacy and are associated with a number of side-effects, restricting the number of patients...

journal_title：Calcified tissue international

authors： Ghouri A,Conaghan PG

更新日期：2020-02-13 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA levels are commonly used as an internal control to normalize gene expression data based on the belief that this gene is constitutively expressed. However, GAPDH mRNA levels increased by more than 2.5-fold in tibiae of hindlimb unloaded female rats compared to L32 m...

journal_title：Calcified tissue international

authors： Maran A,Hefferan TE,Zhang M,Turner RT

更新日期：2004-02-01 00:00:00

abstract：:We investigated whether polymorphisms in PTHR1 are associated with bone mineral density (BMD), to determine whether the association of this gene with BMD was due to effects on attainment of peak bone mass or effects on subsequent bone loss. The PTHR1 gene, including its 14 exons, their exon-intron boundaries, and 1,50...

journal_title：Calcified tissue international

authors： Vilariño-Güell C,Miles LJ,Duncan EL,Ralston SH,Compston JE,Cooper C,Langdahl BL,Maclelland A,Pols HA,Reid DM,Uitterlinden AG,Steer CD,Tobias JH,Wass JA,Brown MA

更新日期：2007-10-01 00:00:00

abstract：:The purpose of this study was to determine whether total serum calcium, parathyroid gland structure, and/or levels of parathyroid hormone, 1,25 and 24,25 DHCC, are altered in pigs with dental and skeletal fluorosis. Eight experimental animals receiving 2 mg F-/kg b.w. per day from age 8-14 months were compared with ei...

journal_title：Calcified tissue international

authors： Andersen L,Richards A,Care AD,Andersen HM,Kragstrup J,Fejerskov O

更新日期：1986-04-01 00:00:00

abstract：:The DMS Lexxos is the first cone-beam dual X-ray absorptiometry (DXA) system capable of performing bone mineral density (BMD) measurements of the spine and hip. By using a two-dimensional (2-D) detector array rather than the linear array used with conventional fan-beam DXA systems, image acquisition time on Lexxos is ...

journal_title：Calcified tissue international

authors： Blake GM,Knapp KM,Fogelman I

更新日期：2005-02-01 00:00:00

abstract：:Recommendations from the FNIH Sarcopenia Project are that appendicular lean mass (ALM, kg) adjusted for body mass index (BMI, kg/m2) be used for identifying low lean mass, with ALM/BMI cutpoints of < 0.789 m2 for men and < 0.512 m2 for women. We report normative ALM/BMI values for Australian adults, and compare the pe...

journal_title：Calcified tissue international

authors： Pasco JA,Holloway-Kew KL,Tembo MC,Sui SX,Anderson KB,Rufus-Membere P,Hyde NK,Williams LJ,Kotowicz MA

更新日期：2019-04-01 00:00:00

abstract：:A case-control study was undertaken to understand the etiopathology of the bone deformities among young children in a fluoride-affected village of the Bihar State. Two villages were selected: one village with high fluoride in drinking water (7.9 +/- 4.15 ppm), and the other village with normal levels of fluoride (0.6 ...

journal_title：Calcified tissue international

authors： Khandare AL,Harikumar R,Sivakumar B

更新日期：2005-06-01 00:00:00

abstract：:Genome-wide association studies (GWAS) have demonstrated that genetic variation at the MADS box transcription enhancer factor 2, polypeptide C (MEF2C) locus is robustly associated with bone mineral density, primarily at the femoral neck. MEF2C is a transcription factor known to operate via the Wnt signaling pathway. O...

journal_title：Calcified tissue international

authors： Johnson ME,Deliard S,Zhu F,Xia Q,Wells AD,Hankenson KD,Grant SF

更新日期：2014-04-01 00:00:00

abstract：:Data on the association between dietary vitamin K intake and fracture risk are limited among Chinese. This study examined such an association in community-dwelling elderly in Hong Kong. We present data from 2,944 subjects (1,605 men, 1,339 women) who participated in a prospective cohort study. Baseline dietary intakes...

journal_title：Calcified tissue international

authors： Chan R,Leung J,Woo J

更新日期：2012-05-01 00:00:00

abstract：:The drawbacks of estrogen restrict the clinical use of hormone replacement therapy, and it would be most helpful to explore new estrogenic substances that could prevent bone loss and be free from any adverse effects. We synthesized a new compound named bone-seeking estrogen (SE2) by combining 17β-estradiol (E2) with i...

journal_title：Calcified tissue international

authors： Zhao Q,Liu X,Zhang L,Shen X,Qi J,Wang J,Qian N,Deng L

更新日期：2013-08-01 00:00:00

abstract：:Glucocorticoid-induced osteoporosis has been reported to be caused by enhanced bone resorption and suppressed bone formation. To clarify whether administration of vitamin K, which enhances bone formation, prevents prednisolone-induced loss of bone mineral density (BMD), a randomized, prospective, controlled study was ...

journal_title：Calcified tissue international

authors： Yonemura K,Kimura M,Miyaji T,Hishida A

更新日期：2000-02-01 00:00:00

abstract：:Molybdenum (Mo), at high concentrations, induces changes in the epiphyseal growth plate through its effects on copper (Cu) metabolism but it is unclear whether or not Mo can induce changes independent of its effects on copper status. To this end, the effect of Mo on longitudinal bone growth was examined in rats. Dieta...

journal_title：Calcified tissue international

authors： Parry NM,Phillippo M,Reid MD,McGaw BA,Flint DJ,Loveridge N

更新日期：1993-09-01 00:00:00

abstract：:Bone mass increases steadily until age 20-30 years, when peak bone mass (PBM) is acquired. Nutrition plays a critical role in achievement of the optimal genetically programmed PBM, with reduction in the risk of osteoporosis later in life. Intake of nutrients can be estimated through the use of various tools; typically...

journal_title：Calcified tissue international

authors： Pampaloni B,Bartolini E,Barbieri M,Piscitelli P,Di Tanna GL,Giolli L,Brandi ML

更新日期：2013-07-01 00:00:00

abstract：:Effects of a single dose of 200 IU of nasal salmon calcitonin (SCT) on calcium metabolism and biochemical markers of bone turnover were investigated in 12 healthy male volunteers in a randomized, placebo-controlled, cross-over design. The nasal spray was given in the morning, and subsequently blood and urine samples w...

journal_title：Calcified tissue international

authors： Thamsborg G,Skousgaard SG,Daugaard H,Schifter S,Kollerup G,Sørensen OH

更新日期：1993-10-01 00:00:00

abstract：:This study examines the efficacy of using radiolabeled thymidine as a measure of bone cell DNA synthesis. The effect of a bone-active peptide on cell proliferation is assessed under different labeling conditions and it is shown that the apparent stimulation in DNA synthesis is due to an increase in participating cells...

journal_title：Calcified tissue international

authors： Puzas JE,Brand JS

更新日期：1986-08-01 00:00:00

abstract：:Quantitative computed tomography (QCT) was compared to dual X-ray absorptiometry (DXA) measured in the lumbar spine of 508 European women defined as normal without fracture (NoF), or osteoporotic (OP), with either vertebral fracture (VF), or peripheral fracture (PF). The correlations between QCT and DXA BMD measuremen...

journal_title：Calcified tissue international

authors： Bergot C,Laval-Jeantet AM,Hutchinson K,Dautraix I,Caulin F,Genant HK

更新日期：2001-02-01 00:00:00

abstract：:Vitamin D supplementation is recommended for women with osteoporosis. In the FOCUS-D trial comparing the combination tablet alendronate plus vitamin D3 5,600 IU (ALN/D) with standard care (SC) prescribed by patients' personal physicians, ALN/D was more effective in improving serum 25(OH)D and bone turnover markers by ...

journal_title：Calcified tissue international

authors： Roux C,Binkley N,Boonen S,Kiel DP,Ralston SH,Reginster JY,Pong A,Rosenberg E,Santora A,FOCUS-D Investigators.

更新日期：2014-02-01 00:00:00

abstract：:The aim of this study was to investigate bone mineral density (BMD) and bone turnover in patients with primary knee osteoarthritis (KOA) and to compare them with generalized OA (GOA) and nonGOA patients. A total of 88 postmenopausal primary KOA patients were studied. OA was graded by using knee radiographs. BMD of the...

journal_title：Calcified tissue international

authors： Naitou K,Kushida K,Takahashi M,Ohishi T,Inoue T

更新日期：2000-05-01 00:00:00

abstract：:Carboxy-terminal pyridinoline cross-linked telopeptide of type I collagen (ICTP) in serum has recently been proposed as a new biochemical marker of bone resorption. In the present study we compared serum ICTP with radiopharmaceutical and histomorphometric measurements of bone turnover in postmenopausal women with mild...

journal_title：Calcified tissue international

authors： Hassager C,Jensen LT,Pødenphant J,Thomsen K,Christiansen C

更新日期：1994-01-01 00:00:00

abstract：:We analyzed the bone microarchitecture of the subcapital and basicervical subregions of the femoral neck in men, to determine whether microarchitectural differences of cortical or trabecular bone can explain differential frequency of subcapital vs. basicervical fractures, especially in aged persons. The study sample e...

journal_title：Calcified tissue international

authors： Cirovic A,Cirovic A,Djonic D,Zivkovic V,Nikolic S,Djuric M,Milovanovic P

更新日期：2020-09-01 00:00:00

abstract：:Diets with a high saturated fat content can produce deleterious effects on the absorption of dietary calcium and consequently an adverse effect on bone mineralization in growing animals. Hence dietary fat may have long-term consequences for skeletal health and skeletal pathologies such as osteoporosis. Whether a diet ...

journal_title：Calcified tissue international

authors： Wohl GR,Loehrke L,Watkins BA,Zernicke RF

更新日期：1998-07-01 00:00:00

abstract：:Teriparatide (TPTD) is known to increase the cortical thickness and porosity. The purpose of the present study was to determine whether switching from TPTD to ibandronate (IBN) would be useful for improving cortical bone parameters as assessed using high-resolution quantitative computed tomography (HR-QCT) analyses in...

journal_title：Calcified tissue international

authors： Iwamoto J,Seki A,Nango N

更新日期：2016-11-01 00:00:00

abstract：:Raman spectroscopy and imaging are known to be valuable tools for the analysis of bone, the determination of protein secondary structure, and the study of the composition of crystalline materials. We have utilized all of these attributes to examine how mechanical loading and the resulting deformation affects bone ultr...

journal_title：Calcified tissue international

authors： Carden A,Rajachar RM,Morris MD,Kohn DH

更新日期：2003-02-01 00:00:00

abstract：:The histologic heterogeneity of osteoporosis relative to normal controls has attracted great interest. There has been controversy as to whether patients with high turnover osteoporosis may convert to a normal or low turnover form, and vice versa. We have studied 44 patients over 12 years by dynamic histomorphometry an...

journal_title：Calcified tissue international

authors： Arlot ME,Bradbeer JN,Edouard C,Green JR,Hesp R,Roux JP,Meunier PJ,Reeve J

更新日期：1993-01-01 00:00:00

abstract：:Anemia is commonly associated with osteoporosis and sarcopenia in older persons. However, there is a common subset of patients identified as osteosarcopenic at a higher risk of adverse outcomes. Whether these patients are also at a higher risk of anemia remains unknown. In this study, we aimed to compare hemoglobin (H...

journal_title：Calcified tissue international

authors： Bani Hassan E,Vogrin S,Hernandez Viña I,Boersma D,Suriyaarachchi P,Duque G

更新日期：2020-08-01 00:00:00

abstract：:A guidance on the assessment and treatment of postmenopausal women at risk from fractures due to osteoporosis was recently published in Osteoporosis International as a joint effort of the International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (Ka...

journal_title：Calcified tissue international

authors： Kanis JA,Cooper C,Rizzoli R,Reginster JY,Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the Committees of Scientific Advisors and National Societies of the Inter

更新日期：2019-03-01 00:00:00

abstract：:Regular exercise and physical activity (PA) are known to be protective factors for maintaining bone mineral density (BMD) and preventing osteoporotic fracture. We investigated the associations between leisure-time PA and BMD in 2,903 premenopausal and 2,267 postmenopausal women in Korea. BMDs of the lumbar spine and f...

journal_title：Calcified tissue international

authors： Kim KZ,Shin A,Lee J,Myung SK,Kim J

更新日期：2012-09-01 00:00:00

abstract：:The developing mandibular condylar growth center consists of a number of histologically distinct cell types. There is an increase in cell volume that takes place from the condylar surface layer through the center of ossification, resulting in a disorganized, irregular cellular pattern. Consequently, the isolation and ...

journal_title：Calcified tissue international

authors： Landesberg R,Proctor RL,Rosier RN,Puzas JE

更新日期：1995-01-01 00:00:00

abstract：:Tumor tissue from a patient with squamous cell carcinoma of the lung and hypercalcemia has been serially implanted into athymic mice. Tumor-bearing mice develop cachexia, hypercalcemia without bone metastases, hypophosphatemia, increased urinary cyclic adenosine monophosphate (cAMP) to creatinine ratio, and undetectab...

journal_title：Calcified tissue international

authors： Abramson EC,Kukla LJ,Shevrin DH,Lad TE,McGuire WP,Kukreja SC

更新日期：1984-09-01 00:00:00

abstract：:The aim of this work was to explore the reduction of fluoride concentrations in the skeleton after stopping experimental fluoride administration. Fluoride was administered to the rats at varying doses (0, 50, 100 ppm in drinking water) and for different lengths of time (4, 13, 25 weeks). A series of fluoride concentra...

journal_title：Calcified tissue international

authors： Li J,Nakagaki H,Kato K,Tsuboi S,Kato S,Morita I,Ohno N,Kameyama Y,Chen R,Robinson C

更新日期：1995-04-01 00:00:00