Abstract:
:Conventional transmission electron microscopy requires an effective dehydration of the tissue specimens under investigation. This dehydration, for which ethanol most often is used, may influence the solubility of the slightly soluble calcium phosphates. To study the behavior of calcium phosphates in ethanol, stable neutral aqueous solutions containing the ions were mixed with ethanol in various ratios at 20 degrees C. After 24 hours, the precipitates formed wee identified by x-ray diffraction to be either apatite, brushite, or amorphous calcium phosphate. The results are discussed with reference to possible formation of calcium phosphate artifacts.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Larsen MJ,Thorsen A,Jensen SJdoi
10.1007/BF02554840subject
Has Abstractpub_date
1985-03-01 00:00:00pages
189-93issue
2eissn
0171-967Xissn
1432-0827journal_volume
37pub_type
杂志文章abstract::The absorption kinetics of intranasal salmon calcitonin were assessed in 4 normal subjects and 9 patients with Klinefelter's syndrome. After administration, absorption occurred within 5 minutes. There was a highly significant correlation between the amount administered and the amount absorbed (r = -0.83, P less than 0...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556097
更新日期:1990-02-01 00:00:00
abstract::It is our hypothesis that interstitial fluid flow plays a role in the bone remodeling response to mechanical loading. The fluid flow-induced expression of three proteins (collagen, osteopontin, and alkaline phosphatase) involved in bone remodeling was investigated. Rat calvarial osteoblasts subjected to pulsatile flui...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900185
更新日期:1997-01-01 00:00:00
abstract::To test the hypothesis that the relationship between fat mass (FM) and bone mineral density (BMD) is mediated by leptin. The study involved 611 individuals aged 20-89 years who were randomly sampled from Ho Chi Minh City (Vietnam). BMD at the femoral neck (FN), lumbar spine (LS), and whole body (WB) was measured by DX...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-016-0196-5
更新日期:2017-01-01 00:00:00
abstract::Aging and sex hormones related changes lead to inflammatory and oxidant conditions, which are involved in the pathogenesis of osteoporosis. Recent studies have suggested that polyphenols may exert a protective effect in such conditions. We assessed the effect of phloridzin (Phlo), a flavonoid exclusively found in appl...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-005-0060-5
更新日期:2005-11-01 00:00:00
abstract::The purpose of the present study was to determine if the type of dietary fat can modify the fatty acid composition and arachidonic acid levels in the alveolar bone phospholipids. Three groups of rats were fed nutritionally adequate semipurified diets containing different lipids: 10% corn oil (control, group I, rich in...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF01351838
更新日期:1993-11-01 00:00:00
abstract::Although radiogenic free radicals are widely used as molecular probes in biological calcified tissues, their nature and their location remain controversial. In the present study we have synthesized and irradiated apatites in which 13CO3(2-) ions substitute hydroxyl or phosphate ions in hydroxyapatite. The 13C-coupling...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Enhanced osteoclast formation and function is a fundamental cause of alterations to bone structure and plays an important role in several diseases impairing bone quality. Recent work revealed that TRP calcium channels 3 and 6 might play a special role in this context. By analyzing the bone phenotype of TRPC6-deficient...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-020-00673-8
更新日期:2020-06-01 00:00:00
abstract::The aim of this study was to investigate the effect of transplanted chondrocytes on endochondral bone formation in cartilage repair tissue. In the knee joint of miniature pigs, cartilage lesions were treated by microfracturing and were then either left empty, covered with a collagen membrane, or treated by matrix-asso...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-009-9288-9
更新日期:2009-11-01 00:00:00
abstract::Sulfotransferase 1E1 (SULT1E1) catalyze estrogen into sulfate conjugation and is involved in the metabolism of phytoestrogen. A community-based cross-sectional study was conducted on 397 Korean women, to evaluate the association between genetic polymorphisms of SULT1E1 and bone mineral density (BMD) and the combined e...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-006-0008-4
更新日期:2006-09-01 00:00:00
abstract::To assess the reductions in bone mass, strength, and turnover in adjuvant-induced arthritic rats and to examine the effect of a new benzamide compound, DU-6712, on these parameters, a 28-day dosing experiment was performed using 8-week-old female Lewis rats. Arthritis was induced by injecting the adjuvant into the hin...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900472
更新日期:1998-06-01 00:00:00
abstract::Calcaneus bone mineral density (BMD) of 738 Japanese women (605 healthy and 133 with osteoporosis) was measured using single X-ray absorptiometry (SXA). A reference range of calcaneus BMD values for healthy Japanese women was established and the usefulness of this method for screening and diagnosis of osteoporosis was...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900665
更新日期:1999-08-01 00:00:00
abstract::SUMMARY. The high variation often observed in the ex vivo fibroblastic-colony forming unit (CFU-f) assay is likely to be due to both biological and experimental variation. To determine whether we could improve experimental methods we developed an alternative method of bone marrow cell (BMC) isolation employing a centr...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900723
更新日期:1999-11-01 00:00:00
abstract::Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of woven and lamellar bone at one or more affected skeletal sites. As a result, bone pain, noti...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-019-00522-3
更新日期:2019-05-01 00:00:00
abstract::Osteoporosis is a bone disease leading to an increased fracture risk. It is considered a complex multifactorial genetic disorder with interaction of environmental and genetic factors. As a candidate gene for osteoporosis, we studied vitamin D binding protein (DBP, or group-specific component, Gc), which binds to and t...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-009-9251-9
更新日期:2009-08-01 00:00:00
abstract::Calcium-acidic phospholipid-phosphate complexes (Ca-PL-PO4) cause hydroxyapatite (HA) deposition in vitro. The acidic phospholipids--phosphatidylserine (PS), phosphatidylinositol (PI), phosphatidylglycerol (PG), and diphosphatidylglycerol (DPG)--all form Ca-PL-PO4 complexes: Nonacidic phospholipids--sphingomyelin (SPL...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Aging is associated with an increase in circulating inflammatory factors. One, the cytokine stromal cell-derived factor 1 (SDF-1 or CXCL12), is critical to stem cell mobilization, migration, and homing as well as to bone marrow stem cell (BMSC), osteoblast, and osteoclast function. SDF-1 has pleiotropic roles in bone ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-017-0245-8
更新日期:2017-06-01 00:00:00
abstract::Age-related loss of skeletal muscle is associated with increased risk of functional limitation and cardiovascular (CV) mortality. In the elderly abdominal aortic calcification (AAC) can increase CV risk by altering aortic properties which may raise blood pressure and increase cardiac workload. This study investigated ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-016-0157-z
更新日期:2016-10-01 00:00:00
abstract::We investigated the ultrastructural distribution and histochemical properties of sulfated glycoconjugates, which could be preserved by glutaraldehyde fixation, in secretory ameloblasts and developing enamel matrix, by use of the high iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining and enzymatic...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556641
更新日期:1988-11-01 00:00:00
abstract::Osteoarthritis (OA), the most prevalent chronic joint disease, increases in prevalence with age, and affects majority of individuals over the age of 65 and is a leading musculoskeletal cause of impaired mobility in the elderly. Because the precise molecular mechanisms which are involved in the degradation of cartilage...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-014-9917-9
更新日期:2014-12-01 00:00:00
abstract::Roux-en-Y gastric bypass surgery (RYGB) is an effective treatment of morbid obesity, with positive effects on obesity-related complications. The treatment is associated with bone loss, which in turn might increase fracture risk. The aim of this study was to evaluate changes in bone mineral density (BMD) and bone archi...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-015-0091-5
更新日期:2016-03-01 00:00:00
abstract::The interaction between estrogens and androgens, with their protective effects in bone, and parathyroid hormone (PTH), a calcitropic peptide hormone, is complex but may be better understood with murine models. The purpose of this study was to characterize skeletal phenotypes of mice deficient in estrogen receptor alph...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-004-0119-8
更新日期:2004-07-01 00:00:00
abstract::Although treatment with intranasal salmon calcitonin (sCT) has been shown to effectively inhibit postmenopausal bone loss, there is still controversy over both timing and the duration of its application. In an open prospective study, we therefore assessed the effect of shortterm intranasal sCT on postmenopausal bone t...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02508638
更新日期:1996-04-01 00:00:00
abstract::The DMS Lexxos is the first cone-beam dual X-ray absorptiometry (DXA) system capable of performing bone mineral density (BMD) measurements of the spine and hip. By using a two-dimensional (2-D) detector array rather than the linear array used with conventional fan-beam DXA systems, image acquisition time on Lexxos is ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-004-0080-6
更新日期:2005-02-01 00:00:00
abstract::The peptide hormone calcitonin is a potent inhibitor of osteoclastic resorption, but it is unstable and poorly absorbed following oral administration. Conjugates of salmon calcitonin covalently linked to low-molecular-weight amphiphilic polymers show improved stability and absorption. The purpose of this study was to ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-002-1051-4
更新日期:2003-09-01 00:00:00
abstract::We hypothesized that reactive oxygen species play an important role in avascular/ischemic osteonecrosis. When isolated chick osteocytes were cultured with hydrogen peroxide, annexin V binding, which is the earliest marker of apoptosis, increased in a dose-dependent fashion. Hydrogen peroxide also induced the activatio...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-001-1110-2
更新日期:2002-09-01 00:00:00
abstract::Relapse after orthodontic tooth movement is a significant problem in orthodontics. The purpose of this study was to examine the efficacy of the osteoclast inhibitor osteoprotegerin-Fc (OPG-Fc) for inhibiting postorthodontic relapse. Rat maxillary molars were moved mesially and allowed to relapse for 24 days. Low-dose ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9579-4
更新日期:2012-04-01 00:00:00
abstract::The orientation of nanoscale mineral platelets was quantitatively evaluated in relation to the shape of lacunae associated with partially embedded osteocytes (osteoblastic-osteocytes) on the surface of deproteinised trabecular bone of adult sheep. By scanning electron microscopy and image analysis, the mean orientatio...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-015-0072-8
更新日期:2016-02-01 00:00:00
abstract::Conventional glucocorticoids exert a negative influence on calcium balance, and long-term treatment with these agents leads to osteopenia. Deflazacort is an oxazoline derivative of prednisolone with documented calcium-sparing properties when compared to prednisone on a weight basis. The purpose of the present study wa...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02556669
更新日期:1987-12-01 00:00:00
abstract::Psoriatic arthritis (PsA) is an inflammatory rheumatic disorder that occurs in patients with psoriasis and predominantly affects musculoskeletal structures, skin, and nails. The etiology of PsA is not well understood but evidence supports an interplay of genetic, immunologic, and environmental factors which promote pa...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-017-0380-2
更新日期:2018-05-01 00:00:00
abstract::The accuracy of a radiographic absorptiometry (RA) technique called digital image processing (DIP), discriminative ability of RA for osteoporotic fracture, and the relationship between RA and dual X-ray absorptiometry (DXA) of the spine and forearm were evaluated. We measured 16 cadaver hands, 32 healthy non-black pre...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900400
更新日期:1998-02-01 00:00:00