Regulation of C-myc protooncogene expression in osteoblastic cells by arachidonic acid metabolites: relationship to proliferation.

abstract：:Tumor tissue from a patient with squamous cell carcinoma of the lung and hypercalcemia has been serially implanted into athymic mice. Tumor-bearing mice develop cachexia, hypercalcemia without bone metastases, hypophosphatemia, increased urinary cyclic adenosine monophosphate (cAMP) to creatinine ratio, and undetectab...

journal_title：Calcified tissue international

authors： Abramson EC,Kukla LJ,Shevrin DH,Lad TE,McGuire WP,Kukreja SC

更新日期：1984-09-01 00:00:00

abstract：:To assess the usefulness of the measurement of the os calcis by ultrasound, a method that probably reflects bone quality as well as density, we have studied 54 women with hip fracture of the proximal femur and a control group. Ultrasound evaluation of the os calcis [broadband ultrasound attenuation (BUA), speed of the...

journal_title：Calcified tissue international

authors： Mautalen C,Vega E,González D,Carrilero P,Otaño A,Silberman F

更新日期：1995-09-01 00:00:00

abstract：:Osteonectin, gamma-carboxyglutamic acid-containing (Gla) protein, and dentin phosphoprotein were covalently attached to sepharose beads and inoculated in solutions at two different degrees of supersaturation with respect to both octacalcium phosphate (OCP) and hydroxyapatite. In both solutions, the inhibitory activity...

journal_title：Calcified tissue international

authors： Doi Y,Horiguchi T,Kim SH,Moriwaki Y,Wakamatsu N,Adachi M,Shigeta H,Sasaki S,Shimokawa H

更新日期：1993-02-01 00:00:00

abstract：:Extracellular ATP, and to a lesser extent adenosine, an ATP metabolite, stimulated cell proliferation in osteoblast-like cells (MC3T3-E1). ATP increased cytosolic Ca2+ due to Ca2+ mobilization from intracellular storage in the same concentration range of the nucleotide as that effective for DNA synthesis, suggesting t...

journal_title：Calcified tissue international

authors： Shimegi S

更新日期：1996-02-01 00:00:00

abstract：:Age-related loss of skeletal muscle is associated with increased risk of functional limitation and cardiovascular (CV) mortality. In the elderly abdominal aortic calcification (AAC) can increase CV risk by altering aortic properties which may raise blood pressure and increase cardiac workload. This study investigated ...

journal_title：Calcified tissue international

authors： Rodríguez AJ,Scott D,Khan B,Khan N,Hodge A,English DR,Giles GG,Ebeling PR

更新日期：2016-10-01 00:00:00

abstract：:Further insight into human tooth enamel, dense fraction (TE), has been obtained by following the change and loss of CO3(2-), OH-, structurally incorporated H2O, Cl-, and, indirectly, HPO4(2-) after TE had been heated in N2 or vacuum in the range 25-1000 degrees C. Quantitative infrared spectroscopic, lattice parameter...

journal_title：Calcified tissue international

authors： Holcomb DW,Young RA

更新日期：1980-01-01 00:00:00

abstract：:A continuous flow organ culture system (CFCS) was used to determine the effect of ascorbic acid on the synthesis of collagen and noncollagenous protein by bone of the alveolar process and periodontal ligament in organ cultures of adult mouse periodontium. For the last 24 h of 2 day cultures, 5 microCi/ml 3H-proline wa...

journal_title：Calcified tissue international

authors： Sodek J,Feng J,Yen EH,Melcher AH

更新日期：1982-07-01 00:00:00

abstract：:The effect of ipriflavone (IP), a synthetic isoflavonoid derivative, on in vivo bone formation was studied in rat perialveolar bone by surgically producing a hole in the mandibular bone. The holes were filled either with powdered IP or with compounds containing no osteoinductive properties such as biostite and Htr (ha...

journal_title：Calcified tissue international

authors： Martini M,Formigli L,Tonelli P,Giannelli M,Amunni F,Naldi D,Brandi ML,Zecchi Orlandini S,Orlandini GE

更新日期：1998-10-01 00:00:00

abstract：:As the correlation of bone mass from childhood to adulthood is unclear, we conducted a long-term prospective observational study to determine if a pediatric bone mass scan could predict adult bone mass. We measured cortical bone mineral content (BMC [g]), bone mineral density (BMD [g/cm(2)]), and bone width (cm) in th...

journal_title：Calcified tissue international

authors： Buttazzoni C,Rosengren BE,Tveit M,Landin L,Nilsson JÅ,Karlsson MK

更新日期：2014-02-01 00:00:00

abstract：:Differences in trabecular and cortical bone loss have been demonstrated clinically, but differences in bone loss at different skeletal sites remain unclear. We examined regional variations in bone loss histomorphometrically in two strains of mice in which osteopenia progresses spontaneously: tiptoe-walking Yoshimura (...

journal_title：Calcified tissue international

authors： Kobayashi Y,Goto S,Tanno T,Yamazaki M,Moriya H

更新日期：1998-05-01 00:00:00

abstract：:The influence of body mass index (BMI) on T scores for total body bone mineral content (TBBMC) and regional bone mineral content (RBMC) was studied in 186 healthy women: 100 postmenopausal, 35 perimenopausal, and 51 premenopausal. The three groups were divided by BMI >25 kg/m2 and BMI <25 kg/m2 and the postmenopausal ...

journal_title：Calcified tissue international

authors： Revilla M,Villa LF,Sánchez-Atrio A,Hernández ER,Rico H

更新日期：1997-08-01 00:00:00

abstract：:Using a combination of gel filtration and DEAE-cellulose chromatography, together with small-scale preparative polyacrylamide gel electrophoresis, we isolated five proteins (amelogenins) from demineralized bovine fetal dental enamel matrix. These purified proteins were characterized by amino acid analysis and gel elec...

journal_title：Calcified tissue international

authors： Fincham AG

更新日期：1979-03-13 00:00:00

abstract：:In this study, we demonstrated that type I collagen matrix induced the expression of osteoblastic phenotypes of bone marrow cells, and that antibone sialoprotein (BSP) monoclonal antibody suppressed the expression of these phenotypes. On the other hand, BSP accelerated the expression of osteoblastic phenotypes of bone...

journal_title：Calcified tissue international

authors： Mizuno M,Imai T,Fujisawa R,Tani H,Kuboki Y

更新日期：2000-05-01 00:00:00

abstract：:The purpose of the present study was to determine if the type of dietary fat can modify the fatty acid composition and arachidonic acid levels in the alveolar bone phospholipids. Three groups of rats were fed nutritionally adequate semipurified diets containing different lipids: 10% corn oil (control, group I, rich in...

journal_title：Calcified tissue international

authors： Alam SQ,Kokkinos PP,Alam BS

更新日期：1993-11-01 00:00:00

abstract：:The European Forsteo Observational Study was designed to examine the effectiveness of teriparatide in postmenopausal women with osteoporosis treated for up to 18 months in normal clinical practice in eight European countries. The incidence of clinical vertebral and nonvertebral fragility fractures, back pain, and heal...

journal_title：Calcified tissue international

authors： Langdahl BL,Rajzbaum G,Jakob F,Karras D,Ljunggren O,Lems WF,Fahrleitner-Pammer A,Walsh JB,Barker C,Kutahov A,Marin F

更新日期：2009-12-01 00:00:00

abstract：:Human osteoblasts were obtained by migration and proliferation of cells from embryonic membranous bone on glass fragments. Light and electron microscopy analyses revealed a typical osteoblast-like appearance with high protein synthesis activity. The cells showed high alkaline phosphatase activity that was associated w...

journal_title：Calcified tissue international

authors： Oliva A,Marrone G,Della Ragione F,Riccio V,Palumbo R,Rossano F,Zappia V

更新日期：1992-11-01 00:00:00

abstract：:Bone turnover markers (BTMs) are widely used for the management of osteoporosis, and the premenopausal reference range is the target value for the treatment of postmenopausal osteoporosis with antiresorbing agents. Three serum BTMs (serum C-telopeptide of type I collagen [CTX], osteocalcin [OC], and N-terminal propept...

journal_title：Calcified tissue international

authors： Adami S,Bianchi G,Brandi ML,Giannini S,Ortolani S,DiMunno O,Frediani B,Rossini M,BONTURNO study group.

更新日期：2008-05-01 00:00:00

abstract：:Bone loss occurs as early as the third decade and its cumulative effect throughout adulthood may impact risk for osteoporosis in later life, however, the genes and environmental factors influencing early bone loss are largely unknown. We investigated the role of genes in the change in bone mineral density (BMD) in par...

journal_title：Calcified tissue international

authors： Shaffer JR,Kammerer CM,Bruder JM,Cole SA,Dyer TD,Almasy L,Maccluer JW,Blangero J,Bauer RL,Mitchell BD

更新日期：2009-02-01 00:00:00

abstract：:The aim of this study was to test whether the nitric oxide (NO) donor sodium nitroprusside (SNP) has an effect on mineralization in ATDC5 cells. Mineralization in ATDC5 cell culture was induced by addition of beta-glycerophosphate or inorganic phosphate, visualized by staining precipitated calcium with an alizarin red...

journal_title：Calcified tissue international

authors： Huitema LF,Vaandrager AB,van Weeren PR,Barneveld A,Helms JB,van de Lest CH

更新日期：2006-03-01 00:00:00

abstract：:Although hypogonadism is a risk factor for bone loss and fractures, the different etiopathophysiology and hormonal profile of classical and obesity-induced hypogonadism may lead to differences in musculoskeletal profile. This is a cross-sectional study of hypogonadal men between 40 and 74 years old. Our outcomes inclu...

journal_title：Calcified tissue international

authors： Aguirre LE,Colleluori G,Dorin R,Robbins D,Chen R,Jiang B,Qualls C,Villareal DT,Armamento-Villareal R

更新日期：2017-12-01 00:00:00

abstract：:Urinary pyridinoline (pyr) and deoxypyridinoline (dpyr) are new markers for bone resorption, and serum osteocalcin reportedly indicates osteoblastic activity. Recently, a new ultrasound bone densitometer instrument has been developed that measures ultrasonic properties of the os calcis, namely, the speed of sound (SOS...

journal_title：Calcified tissue international

authors： Kawana K,Kushida K,Takahashi M,Ohishi T,Denda M,Yamazaki K,Inoue T

更新日期：1994-12-01 00:00:00

abstract：:Dual-photon absorptiometry (153Gd) was used to measure bone mineral of the total body and major anatomical areas. Patients with osteoporosis (male = 11, female = 18) and with renal osteodystrophy (n = 17) were significantly below (20%) normal females (n = 72) and males (n = 13) at most sites. In the osteoporotic patie...

journal_title：Calcified tissue international

authors： Mazess RB,Peppler WW,Chesney RW,Lange TA,Lindgren U,Smith E Jr

更新日期：1984-01-01 00:00:00

abstract：:Regular exercise and physical activity (PA) are known to be protective factors for maintaining bone mineral density (BMD) and preventing osteoporotic fracture. We investigated the associations between leisure-time PA and BMD in 2,903 premenopausal and 2,267 postmenopausal women in Korea. BMDs of the lumbar spine and f...

journal_title：Calcified tissue international

authors： Kim KZ,Shin A,Lee J,Myung SK,Kim J

更新日期：2012-09-01 00:00:00

abstract：:The acute-phase response (APR) is a frequent occurrence after infusion of zoledronic acid and is caused by activation of γδ T cells. Vitamin D receptor is expressed in immune cells, and vitamin D has immunomodulatory properties. The aim of this prospective study was to test the effect of vitamin D (cholecalciferol) on...

journal_title：Calcified tissue international

authors： Catalano A,Morabito N,Atteritano M,Basile G,Cucinotta D,Lasco A

更新日期：2012-04-01 00:00:00

abstract：:Inoculation of Moloney murine sarcoma virus (M-MSV) into shank muscles of adult NMRI mice resulted in localized sarcoma and periosteal membrane proliferation with subsequent periosteal bone formation. Newly formed bone arose from outer surface of shank bones. Two weeks after M-MSV inoculation the width of bone cortex ...

journal_title：Calcified tissue international

authors： Włodarski K,Kobus M,Luczak M,Dołowy J

更新日期：1981-01-01 00:00:00

abstract：:The interaction between estrogens and androgens, with their protective effects in bone, and parathyroid hormone (PTH), a calcitropic peptide hormone, is complex but may be better understood with murine models. The purpose of this study was to characterize skeletal phenotypes of mice deficient in estrogen receptor alph...

journal_title：Calcified tissue international

authors： Tözüm TF,Oppenlander ME,Koh-Paige AJ,Robins DM,McCauley LK

更新日期：2004-07-01 00:00:00

abstract：:Polymorphisms in the region of the gene for the vitamin D receptor (VDR) (chromosome 12q12-14) have been associated with differences in bone mineral density (BMD) in some studies but not in others. Because linkage analysis assesses allele sharing identical-by-descent among relatives instead of the association of a par...

journal_title：Calcified tissue international

authors： Zee RY,Myers RH,Hannan MT,Wilson PW,Ordovas JM,Schaefer EJ,Lindpaintner K,Kiel DP

更新日期：2000-12-01 00:00:00

abstract：:Because of the variability of collagen crosslinks, their use as markers for bone resorption is often criticized. We hypothesized that the variability could be reduced by collecting urine for 24 hours (or longer) instead of using single voids, and by not normalizing to creatinine. Urine samples were collected from 22 h...

journal_title：Calcified tissue international

authors： Smith SM,Dillon EL,DeKerlegand DE,Davis-Street JE

更新日期：2004-04-01 00:00:00

abstract：:Bone tissue is a source of growth factors; among them, insulinlike growth factor I (IGF-I) is probably an important local regulator of bone formation. This study has been carried out in order to assess the effects of natural menopause on plasma concentrations of IGF-I in the first 6 years after the cessation of gonada...

journal_title：Calcified tissue international

authors： Romagnoli E,Minisola S,Carnevale V,Scarda A,Rosso R,Scarnecchia L,Pacitti MT,Mazzuoli G

更新日期：1993-07-01 00:00:00

abstract：:Data on the association between dietary vitamin K intake and fracture risk are limited among Chinese. This study examined such an association in community-dwelling elderly in Hong Kong. We present data from 2,944 subjects (1,605 men, 1,339 women) who participated in a prospective cohort study. Baseline dietary intakes...

journal_title：Calcified tissue international

authors： Chan R,Leung J,Woo J

更新日期：2012-05-01 00:00:00