Early growth response gene 1 regulates bone properties in mice.

abstract：:The interaction between estrogens and androgens, with their protective effects in bone, and parathyroid hormone (PTH), a calcitropic peptide hormone, is complex but may be better understood with murine models. The purpose of this study was to characterize skeletal phenotypes of mice deficient in estrogen receptor alph...

journal_title：Calcified tissue international

authors： Tözüm TF,Oppenlander ME,Koh-Paige AJ,Robins DM,McCauley LK

更新日期：2004-07-01 00:00:00

abstract：:Ribbon-like crystals, from developing enamel of human fetuses, were studied by high resolution electron microscopy. These crystals were classically described as the first organized mineral formed during amelogenesis. They were characterized by a mean width-to-thickness ratio (W.T-1) of 9.5, and 40% were bent. On latti...

journal_title：Calcified tissue international

authors： Cuisinier FJ,Steuer P,Senger B,Voegel JC,Frank RM

更新日期：1992-10-01 00:00:00

abstract：:Men and women (n = 518) receiving moderate-to-high doses of corticosteroids were enrolled in two studies with similar protocols and randomly assigned to receive either placebo or risedronate (2.5 or 5 mg) for 1 year. All patients received daily calcium supplementation (500-1000 mg), and most also received supplemental...

journal_title：Calcified tissue international

authors： Wallach S,Cohen S,Reid DM,Hughes RA,Hosking DJ,Laan RF,Doherty SM,Maricic M,Rosen C,Brown J,Barton I,Chines AA

更新日期：2000-10-01 00:00:00

abstract：:The present report compares the effects of different membrane phospholipid (PL)-cholesterol compositions on the kinetics of liposome-mediated formation of calcium phosphates from metastable solutions (2.25 mM CaCl2; 1.5 mM KH2PO4) at 22 degrees C, pH 7.4 and 240 mOsm. In most experiments, the liposomes were composed o...

journal_title：Calcified tissue international

authors： Skrtic D,Eanes ED

更新日期：1992-03-01 00:00:00

abstract：:Bone turnover markers (BTMs) are widely used for the management of osteoporosis, and the premenopausal reference range is the target value for the treatment of postmenopausal osteoporosis with antiresorbing agents. Three serum BTMs (serum C-telopeptide of type I collagen [CTX], osteocalcin [OC], and N-terminal propept...

journal_title：Calcified tissue international

authors： Adami S,Bianchi G,Brandi ML,Giannini S,Ortolani S,DiMunno O,Frediani B,Rossini M,BONTURNO study group.

更新日期：2008-05-01 00:00:00

abstract：:Mice deficient in the chloride channel ClC-7, which is likely involved in acidification of the resorption lacuna, display severe osteopetrosis. To fully characterize the osteopetrotic phenotype, the phenotypes of osteoclasts and osteoblasts were evaluated. ClC-7(-/-) mice and their corresponding wild-type littermates ...

journal_title：Calcified tissue international

authors： Neutzsky-Wulff AV,Karsdal MA,Henriksen K

更新日期：2008-12-01 00:00:00

abstract：:We examined differences in patients' survival after hip fracture (HF) and risk for subsequent HF among patients treated with oral and intravenous bisphosphonates (oBPs, iBPs), denosumab (DMAB), and patients without therapy. We used data from all patients in Austria aged ≥ 50 who sustained a HF between 2012 and 2017 an...

journal_title：Calcified tissue international

authors： Behanova M,Reichardt B,Stamm TA,Zwerina J,Klaushofer K,Kocijan R

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to follow the changes in bone mineral density (BMD) and biochemical markers of bone turnover in 10 children (7.5-17.5 years of age) with severe juvenile idiopathic arthritis (JIA), during a 3-year therapy with salmon calcitonin (100 IU/day 2 months on and 2 off for a year and 200 IU/day for 2...

journal_title：Calcified tissue international

authors： Siamopoulou A,Challa A,Kapoglou P,Cholevas V,Mavridis AK,Lapatsanis PD

更新日期：2001-07-01 00:00:00

abstract：:The acute-phase response (APR) is frequently observed in patients treated with intravenous (iv) zoledronate (ZOL). We investigated whether a short course of rosuvastatin (ROSU) could attenuate the ZOL--induced APR through blocking the mevalonate pathway at a proximal level. Twenty-eight osteoporotic postmenopausal wom...

journal_title：Calcified tissue international

authors： Makras P,Anastasilakis AD,Polyzos SA,Bisbinas I,Sakellariou GT,Papapoulos SE

更新日期：2011-05-01 00:00:00

abstract：:Osteoporosis is a common disease among patients undergoing transplantation. Its prevalence and complications have been well described in solid organ recipients, especially kidney, liver, and heart. However, studies in bone marrow transplantation (BMT) are scarce. Among the mechanisms invoked in the pathogenesis of BMT...

journal_title：Calcified tissue international

authors： Castañeda S,Carmona L,Carvajal I,Arranz R,Díaz A,García-Vadillo A

更新日期：1997-04-01 00:00:00

abstract：:The severest long-term complications of orthopedic joint-prostheses are associated with loosening of the implant-bone interface, due to adverse reactions in bone and subsequent weakening of the connection between the two materials. Mechanical stresses, caused by joint loading, play a key role in the adaption of interf...

journal_title：Calcified tissue international

authors： Huiskes R,Nunamaker D

更新日期：1984-01-01 00:00:00

abstract：:Arterial calcification leading to increased arterial stiffness, a powerful risk factor for cardiovascular disease, may underlie the association of osteoporosis with cardiovascular disease in postmenopausal women. Osteoprotegerin (OPG), an indirect inhibitor of osteoclastogenesis, may be involved in arterial calcificat...

journal_title：Calcified tissue international

authors： Frost ML,Grella R,Millasseau SC,Jiang BY,Hampson G,Fogelman I,Chowienczyk PJ

更新日期：2008-08-01 00:00:00

abstract：:We separated osteoclasts from bone and observed the effect of several known and potential mediators of the control of bone resorption on their cytoplasmic motility. We already found that calcitonin (CT), a hormone that inhibits bone resorption, regularly causes complete inhibition of cytoplasmic motility, specific for...

journal_title：Calcified tissue international

authors： Chambers TJ,Dunn CJ

更新日期：1983-07-01 00:00:00

abstract：:Ascorbic acid is a required cofactor in the hydroxylations of lysine and proline necessary for collagen formation; its role in bone cell differentiation and formation is less well characterized. This study examines the cross-sectional relation between dietary vitamin C intake and bone mineral density (BMD) in women fr...

journal_title：Calcified tissue international

authors： Hall SL,Greendale GA

更新日期：1998-09-01 00:00:00

abstract：:To characterize osteopenic changes in ovariectomized (OVX) rats as a function of time, female Sprague Dawley rats (240 g body weight, 90 days old) were subjected to bilateral ovariectomy or sham surgery and killed at various times from 14-180 days postovariectomy. The proximal tibial metaphysis was processed undecalci...

journal_title：Calcified tissue international

authors： Wronski TJ,Cintrón M,Dann LM

更新日期：1988-09-01 00:00:00

abstract：:Cytochemical staining of normal human bone cells in monolayer cultures for alkaline phosphatase (ALP) indicated that the cultures contained mixed-cell populations. Time course evaluations of the cytochemical staining revealed, in addition to the ALP-negative cell population, at least two subpopulations of ALP-positive...

journal_title：Calcified tissue international

authors： Matsuyama T,Lau KH,Wergedal JE

更新日期：1990-11-01 00:00:00

abstract：:Abnormal PTH secretion and cell growth in hyperparathyroid tissues are accompanied with reduced expression of Ca2+-sensing receptor (CaR) which plays a key role in Ca-regulated PTH release. In this study, we examined the receptor expression in parathyroid adenomas using specific anti-CaR antibody and investigated rela...

journal_title：Calcified tissue international

authors： Kaneko C,Mizunashi K,Tanaka M,Uzuki M,Kikuchi M,Sawai T,Goto MM

更新日期：1999-03-01 00:00:00

abstract：:Osteoarthritis (OA) is a chronic, debilitating disease affecting millions of people worldwide. Management of OA involves pharmacological and non-pharmacological approaches. Conventional pharmacological treatments have limited efficacy and are associated with a number of side-effects, restricting the number of patients...

journal_title：Calcified tissue international

authors： Ghouri A,Conaghan PG

更新日期：2020-02-13 00:00:00

abstract：:Lumbar spine bone mass and density were measured with Dual photon absorptiometry (DPA) in 60 patients with crush fractures and 60 age-matched normal women. Short-term reproducibility of bone mineral density (BMD) was 1.3% in normal women and 2.5% in osteoporotic women; long-term reproducibility in normal women was 2.2...

journal_title：Calcified tissue international

authors： Pouilles JM,Tremollieres F,Louvet JP,Fournie B,Morlock G,Ribot C

更新日期：1988-12-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA levels are commonly used as an internal control to normalize gene expression data based on the belief that this gene is constitutively expressed. However, GAPDH mRNA levels increased by more than 2.5-fold in tibiae of hindlimb unloaded female rats compared to L32 m...

journal_title：Calcified tissue international

authors： Maran A,Hefferan TE,Zhang M,Turner RT

更新日期：2004-02-01 00:00:00

abstract：:Administration of active vitamin D sterols to treat secondary hyperparathyroidism in patients with chronic kidney disease receiving dialysis has been associated with elevated serum calcium and phosphorus levels, which may lead to increased risk of vascular calcification. However, calcimimetics, by binding to the parat...

journal_title：Calcified tissue international

authors： Shalhoub V,Shatzen E,Henley C,Boedigheimer M,McNinch J,Manoukian R,Damore M,Fitzpatrick D,Haas K,Twomey B,Kiaei P,Ward S,Lacey DL,Martin D

更新日期：2006-12-01 00:00:00

abstract：:The relationship between oral indicators and bone mineral density (BMD) has been studied by many investigators, with mixed and complex results. The purpose of the present cross-sectional study was to evaluate the associations of periodontal conditions and tooth loss with metacarpal BMD (m-BMD) in a community-based coh...

journal_title：Calcified tissue international

authors： Inagaki K,Kurosu Y,Yoshinari N,Noguchi T,Krall EA,Garcia RI

更新日期：2005-07-01 00:00:00

abstract：:Interleukin (IL)-6 is a bone-resorbing cytokine that acts primarily on osteoclast progenitors to stimulate both proliferation and differentiation. Glucocorticoids (GC) down-regulate IL-6 synthesis in different cell types, including osteoblasts. Given the fact that bone remodeling is a tightly controlled process, it is...

journal_title：Calcified tissue international

authors： Dovio A,Masera RG,Sartori ML,Racca S,Angeli A

更新日期：2001-11-01 00:00:00

abstract：:The association of dietary patterns and bone health is not yet well known, and findings from the rare previous studies conducted on this issue are contradictory. We assessed the dietary patterns in relation to bone mineral density (BMD) in a sample of menopausal Iranian women. In this cross-sectional study, 160 menopa...

journal_title：Calcified tissue international

authors： Karamati M,Jessri M,Shariati-Bafghi SE,Rashidkhani B

更新日期：2012-07-01 00:00:00

abstract：:Dickkopf-1 (DKK1) and sclerostin are antagonists of the Wnt/β-catenin pathway and decreased expression of either results in increased bone formation and mass. As both affect the same signaling pathway, we aimed to elucidate the redundancy and/or compensation of sclerostin and DKK1. Weekly sclerostin antibody (Scl-Ab) ...

journal_title：Calcified tissue international

authors： Morse A,Cheng TL,Schindeler A,McDonald MM,Mohanty ST,Kneissel M,Kramer I,Little DG

更新日期：2018-09-01 00:00:00

abstract：:The aim of this study was to investigate bone mineral density (BMD) and bone turnover in patients with primary knee osteoarthritis (KOA) and to compare them with generalized OA (GOA) and nonGOA patients. A total of 88 postmenopausal primary KOA patients were studied. OA was graded by using knee radiographs. BMD of the...

journal_title：Calcified tissue international

authors： Naitou K,Kushida K,Takahashi M,Ohishi T,Inoue T

更新日期：2000-05-01 00:00:00

abstract：:Bruck syndrome is a rare autosomal recessive form of osteogenesis imperfecta (OI), which is mainly characterized by joint contractures and recurrent fragility fractures. Mutations in FKBP10 and PLOD2 were identified as the underlying genetic defects of Bruck syndrome. Here we investigated the phenotypes and the pathog...

journal_title：Calcified tissue international

authors： Lv F,Xu X,Song Y,Li L,Asan,Wang J,Yang H,Wang O,Jiang Y,Xia W,Xing X,Li M

更新日期：2018-03-01 00:00:00

abstract：:We assessed the bone mineral density (BMD) of 16 matched sets of cadaveric proximal femurs and feet using dual-energy x-ray absorptiometry (DXA). We also estimated the femoral neck length from the DXA scans. Quantitative ultrasound densitometry was used to measure the velocity of sound and broadband ultrasound attenua...

journal_title：Calcified tissue international

authors： Bouxsein ML,Courtney AC,Hayes WC

更新日期：1995-02-01 00:00:00

abstract：:A 56 year-old man with a 2-year history of transitional-cell carcinoma of the urinary bladder presented with back pain and diffuse radiological osteosclerosis. Laboratory studies revealed borderline-low ionized serum calcium, and markedly elevated serum alkaline phosphatase (ALP) activity and serum osteocalcin. Serum ...

journal_title：Calcified tissue international

authors： Liel Y,Maor E,Ariad S,Lowenthal MN

更新日期：1998-12-01 00:00:00

abstract：:Parathyroid hormone (PTH), hPTH-(1-84), and its hPTH-(1-34), hPTH-(1-31)NH2, and hPTH-(1-30)NH2 fragments reduced the tail artery pressure in anesthetized female Sprague-Dawley rats by 42.4-67.1% within about 1 minute after injection into a femoral vein, but reduced the pressure by only 8.5-36.2% 2-19 minutes after su...

journal_title：Calcified tissue international

authors： Whitfield JF,Morley P,Ross V,Preston E,Soska M,Barbier JR,Isaacs RJ,Maclean S,Ohannessian-Barry L,Willick GE

更新日期：1997-03-01 00:00:00