Characterization of the bone phenotype in ClC-7-deficient mice.

abstract：:Two rheumatic syndromes associated with deposition of calcium phosphate crystals in soft tissues of the shoulder have prompted us to study the cellular mechanisms of calcium phosphate crystal solubilization. Synthetic 45Ca labeled calcium phosphate crystal aggregates were solubilized by cultured human fibroblasts or m...

journal_title：Calcified tissue international

authors： Evans RW,Cheung HS,McCarty DJ

更新日期：1984-12-01 00:00:00

abstract：:Our knowledge of the developmental changes in the concentration of serum and bone osteocalcin (OC) is limited. To investigate the interrelationship between skeletal and circulatory OC during acquisition of peak bone density in mice, we examined the temporal changes in the concentration of serum and bone OC from 3 to 1...

journal_title：Calcified tissue international

authors： Li X,Srivastava AK,Gu W,Masinde G,Mohan S,Baylink DJ

更新日期：2002-11-01 00:00:00

abstract：:The evidence now strongly supports a central role for oestrogen in the maintenance of the normal female skeleton. Loss of endogenous oestrogen leads to a period of accelerated bone loss which can be prevented with appropriate oestrogen replacement. The route of administration is not important provided adequate dosages...

journal_title：Calcified tissue international

authors： Hillard TC,Stevenson JC

更新日期：1991-01-01 00:00:00

abstract：:We carried out a clinical trial of 1 alpha-hydroxycholecalciferol [1 alpha(OH)D3] at a dose of 1.0 microgram a day on 7 patients with psoriasis vulgaris. These patients had been treated by topical applications of corticosteroids before this study without improvement, and during the clinical trial, treatment of topical...

journal_title：Calcified tissue international

authors： Takamoto S,Onishi T,Morimoto S,Imanaka S,Yukawa S,Kozuka T,Kitano Y,Seino Y,Kumahara Y

更新日期：1986-12-01 00:00:00

abstract：:The recent advancement of high resolution magnetic resonance imaging has opened up new avenues for the determination of structural characteristics of the trabecular network, which may significantly improve the diagnosis of osteoporosis. An analysis of the calcaneus in healthy women has shown similar age-related change...

journal_title：Calcified tissue international

authors： Engelke K,Hahn M,Takada M,Vogel M,Ouyang X,Delling G,Genant HK

更新日期：2001-03-01 00:00:00

abstract：:The increased uptake of bone-seeking radionuclides following a fracture has been stated to be due to an increase in bone blood flow, resulting in an increase in capillary surface area available for exchange. This paper examines the relationship between the maximum instantaneous extraction of 99mTc-MDP and blood flow i...

journal_title：Calcified tissue international

authors： McCarthy ID,Hughes SP

更新日期：1983-07-01 00:00:00

abstract：:Men and women (n = 518) receiving moderate-to-high doses of corticosteroids were enrolled in two studies with similar protocols and randomly assigned to receive either placebo or risedronate (2.5 or 5 mg) for 1 year. All patients received daily calcium supplementation (500-1000 mg), and most also received supplemental...

journal_title：Calcified tissue international

authors： Wallach S,Cohen S,Reid DM,Hughes RA,Hosking DJ,Laan RF,Doherty SM,Maricic M,Rosen C,Brown J,Barton I,Chines AA

更新日期：2000-10-01 00:00:00

abstract：:At 4 and 24 hours after injection of (35S)sulfate, there were 22-67% fewer silver grains on conventionally fixed sections than on sections fixed by cryotechniques. Differences were smaller when (3H) glucosamine was chosen as precursor. The number of silver grains increased between 4 and 24 hours in predentine and in a...

journal_title：Calcified tissue international

authors： Goldberg M,Escaig F

更新日期：1985-09-01 00:00:00

abstract：:Aging is associated with an increase in circulating inflammatory factors. One, the cytokine stromal cell-derived factor 1 (SDF-1 or CXCL12), is critical to stem cell mobilization, migration, and homing as well as to bone marrow stem cell (BMSC), osteoblast, and osteoclast function. SDF-1 has pleiotropic roles in bone ...

journal_title：Calcified tissue international

authors： Carbone LD,Bůžková P,Fink HA,Robbins JA,Bethel M,Hamrick MW,Hill WD

更新日期：2017-06-01 00:00:00

abstract：:Vit-D-Dependent calcium binding protein and parvalbumin have both been detected in ameloblasts and calcified cartilage by immunohistochemical techniques. These two Ca2+ binding proteins may play a crucial role in the local accumulation of Ca2+ ions during the process of mineralization. The mechanisms underlying the de...

journal_title：Calcified tissue international

authors： Celio MR,Norman AW,Heizmann CW

更新日期：1984-01-01 00:00:00

abstract：:To assess whether vertebral fractures are associated with osteopenia in chronic alcoholic patients, a transversal study was carried out in 76 chronic alcoholic males and 62 age-matched healthy males. Lumbar bone mineral density (BMD) by dual photon absorptiometry and spinal chest X-ray films were done in all patients....

journal_title：Calcified tissue international

authors： Peris P,Guañabens N,Parés A,Pons F,del Rio L,Monegal A,Surís X,Caballería J,Rodés J,Muñoz-Gómez J

更新日期：1995-08-01 00:00:00

abstract：:Compressive strength index (CSI) of the femoral neck is a parameter that integrates the information of bone mineral density (BMD), femoral neck width (FNW), and body weight. CSI is considered to have the potential to improve the performance of assessment for hip fracture risk. However, studies on CSI have been rare. I...

journal_title：Calcified tissue international

authors： Yu N,Liu YJ,Pei Y,Zhang L,Lei S,Kothari NR,Li DY,Papasian CJ,Hamilton J,Cai JQ,Deng HW

更新日期：2010-10-01 00:00:00

abstract：:This randomized, double-blind study assessed the antifracture efficacy and safety of intermittent intravenous (IV) ibandronate versus oral daily risedronate in Japanese patients with primary osteoporosis. Ambulatory patients aged ≥60 years were randomized to receive 0.5 or 1 mg/month IV ibandronate plus oral daily pla...

journal_title：Calcified tissue international

authors： Nakamura T,Nakano T,Ito M,Hagino H,Hashimoto J,Tobinai M,Mizunuma H,MOVER Study Group.

更新日期：2013-08-01 00:00:00

abstract：:MicroRNAs (miRNAs/miRs) are important biomarkers for the progression of intervertebral disc degeneration (IDD). We investigated the role of miR-30d in IDD progression through its interactions with forkhead box O3 (FOXO3) and C-X-C motif ligand 10 (CXCL10). We first measured the expression of miR-30d, FOXO3, and CXCL10...

journal_title：Calcified tissue international

authors： Xia P,Gao X,Li F,Shao L,Sun Y

更新日期：2021-02-01 00:00:00

abstract：:To determine the relationships among nutrients intake, bone mass, and bone turnover in women we have investigated these issues in a population-based, cross-sectional, observational study in one county in central Sweden. A total of 175 women aged 28-74 at entry to the study were included. Dietary assessment was made by...

journal_title：Calcified tissue international

authors： Michaëlsson K,Holmberg L,Mallmin H,Wolk A,Bergström R,Ljunghall S

更新日期：1995-08-01 00:00:00

abstract：:Biochemical markers applicable to the ovariectomized rat model can provide important tools for studying the bone remodeling process in this animal model of postmenopausal osteoporosis. We describe the development and application of two biochemical markers, a C-telopeptide (of type-I collagen) enzyme-linked immunosorbe...

journal_title：Calcified tissue international

authors： Srivastava AK,Bhattacharyya S,Castillo G,Wergedal J,Mohan S,Baylink DJ

更新日期：2000-06-01 00:00:00

abstract：:We studied the influence of age, gender, latitude, season, diet and ethnicity on plasma 25-hydroxyvitamin D 25 OHD, PTH, 1,25-dihydroxyvitamin D, vitamin D-binding protein, bone-specific alkaline phosphatase, and osteocalcin levels in 46 Greenlanders living in Nuuk (64 degrees N) on a traditional fare (group A), 45 Gr...

journal_title：Calcified tissue international

authors： Rejnmark L,Jørgensen ME,Pedersen MB,Hansen JC,Heickendorff L,Lauridsen AL,Mulvad G,Siggaard C,Skjoldborg H,Sørensen TB,Pedersen EB,Mosekilde L

更新日期：2004-03-01 00:00:00

abstract：:The effect of ipriflavone (IP), a synthetic isoflavonoid derivative, on in vivo bone formation was studied in rat perialveolar bone by surgically producing a hole in the mandibular bone. The holes were filled either with powdered IP or with compounds containing no osteoinductive properties such as biostite and Htr (ha...

journal_title：Calcified tissue international

authors： Martini M,Formigli L,Tonelli P,Giannelli M,Amunni F,Naldi D,Brandi ML,Zecchi Orlandini S,Orlandini GE

更新日期：1998-10-01 00:00:00

abstract：:The effects of a series of novel phosphonates on the kinetics of mineral development in an ionophore-primed 7:2:1 phosphatidylcholine (PC): dicetylphosphate (DCP): cholesterol (Chol) liposomal model system are reported. When present at 2.5 micromol/liter or 25 micromol/liter concentrations in the solution surrounding ...

journal_title：Calcified tissue international

authors： Skrtic D,Eidelman N,Golomb G,Breuer E,Eanes ED

更新日期：1996-05-01 00:00:00

abstract：:Proteoglycans are recognized to inhibit calcium pyrophosphate dihydrate (CPPD) crystal formation but the mechanisms are not known. To study the role of carboxylate (-CO2-) ligands, the possible inhibitor effects of sodium acetate, sodium D-glucuronate, disodium malate, and trisodium citrate were studied using solution...

journal_title：Calcified tissue international

authors： Cheng PT,Pritzker KP

更新日期：1988-01-01 00:00:00

abstract：:To test the hypothesis that the relationship between fat mass (FM) and bone mineral density (BMD) is mediated by leptin. The study involved 611 individuals aged 20-89 years who were randomly sampled from Ho Chi Minh City (Vietnam). BMD at the femoral neck (FN), lumbar spine (LS), and whole body (WB) was measured by DX...

journal_title：Calcified tissue international

authors： Ho-Pham LT,Lai TQ,Nguyen UD,Bui QV,Nguyen TV

更新日期：2017-01-01 00:00:00

abstract：:Vitamin K promotes the formation of gamma-carboxylated glutamate (GLA) in several protein species. GLA residues have a high affinity for the Ca ion. In the present study, we tested the hypothesis that experimental vitamin K deficiency in rats could induce changes in Ca metabolism. Vitamin K depletion, which was associ...

journal_title：Calcified tissue international

authors： Robert D,Jorgetti V,Lacour B,Leclerq M,Cournot-Witmer G,Ulmann A,Drüeke T

更新日期：1985-03-01 00:00:00

abstract：:To investigate the effect of low doses of intranasal salmon calcitonin on plasma cyclic AMP (cAMP) and serum ionized calcium, 40 healthy postmenopausal women were randomized to receive a single dose of either placebo or 50, 100, or 200 IU of salmon calcitonin as a nasal spray. Blood samples were collected throughout a...

journal_title：Calcified tissue international

authors： Thamsborg G,Storm TL,Brinch E,Sykulski R,Fogh-Andersen N,Holmegaard SN,Sørensen OH

更新日期：1990-01-01 00:00:00

abstract：:Ribbon-like crystals, from developing enamel of human fetuses, were studied by high resolution electron microscopy. These crystals were classically described as the first organized mineral formed during amelogenesis. They were characterized by a mean width-to-thickness ratio (W.T-1) of 9.5, and 40% were bent. On latti...

journal_title：Calcified tissue international

authors： Cuisinier FJ,Steuer P,Senger B,Voegel JC,Frank RM

更新日期：1992-10-01 00:00:00

abstract：:It has been suggested that oxidative stress is associated with the pathogenesis of osteoporosis. The objective of this study was to explore the association between a marker of oxidative stress and either bone turnover markers or bone mineral density (BMD) in postmenopausal women. In addition, the effects of oxidative ...

journal_title：Calcified tissue international

authors： Baek KH,Oh KW,Lee WY,Lee SS,Kim MK,Kwon HS,Rhee EJ,Han JH,Song KH,Cha BY,Lee KW,Kang MI

更新日期：2010-09-01 00:00:00

abstract：:The purpose of this study was to estimate clinical validity of a new available immunoradiometric assay for circulating intact human BGP (N-tact Osteo SP) by measuring this protein in a large number of normal subjects and patients with the most common metabolic bone diseases. One hundred normal subjects were studied in...

journal_title：Calcified tissue international

authors： Minisola S,Pacitti MT,Romagnoli E,Rosso R,Carnevale V,Caravella P,Scillitani A,Dicembrino F

更新日期：1999-05-01 00:00:00

abstract：:Experimental analysis with paired femurs provides the opportunity to study within-person differences in fracture type and associated structural side differences. We hypothesized that different fracture types in the hips of a subject are associated with structural asymmetry. Bone mineral density (BMD) and structural me...

journal_title：Calcified tissue international

authors： Thevenot J,Pulkkinen P,Kuhn V,Eckstein F,Jämsä T

更新日期：2010-09-01 00:00:00

abstract：:Our objective was to assess the effects of HIV infection and antiretroviral therapy on trabecular and cortical microarchitecture in postmenopausal minority women. A subgroup of 106 (46 HIV-infected, 60 uninfected) postmenopausal Hispanic and African American women from an established cohort had areal bone mineral dens...

journal_title：Calcified tissue international

authors： Yin MT,Shu A,Zhang CA,Boutroy S,McMahon DJ,Ferris DC,Colon I,Shane E

更新日期：2013-06-01 00:00:00

abstract：:During mechanical unloading, endothelial cells reduce osteogenesis and increase bone resorption. Here we describe the feedback response of endothelial cells to unloaded osteoblasts. Primary endothelial cells, ex vivo mouse aortic rings and chicken egg yolk membranes were incubated with conditioned medium from mouse pr...

journal_title：Calcified tissue international

authors： Veeriah V,Paone R,Chatterjee S,Teti A,Capulli M

更新日期：2019-03-01 00:00:00

abstract：:We compared indices of three-dimensional microstructure of iliac trabecular bone between 26 patients with vertebral compression fractures due to postmenopausal osteoporosis and 24 control subjects without vertebral fracture, who were matched for age, sex, race, menopausal status, and several densitometric and histolog...

journal_title：Calcified tissue international

authors： Kleerekoper M,Villanueva AR,Stanciu J,Rao DS,Parfitt AM

更新日期：1985-12-01 00:00:00