Abstract:
:At 4 and 24 hours after injection of (35S)sulfate, there were 22-67% fewer silver grains on conventionally fixed sections than on sections fixed by cryotechniques. Differences were smaller when (3H) glucosamine was chosen as precursor. The number of silver grains increased between 4 and 24 hours in predentine and in a 30-micron band of dentine that had already undergone mineralization. Only a few grains were observed, however, in the 5-micron dentine band located at the mineralization front. This suggests that glycoaminoglycans, which in predentine have a space-filling role, facilitate transport and diffusion and inhibit mineralization, may limit crystal growth in dentine once a certain degree of apatite formation has been reached. All these properties are correlated with the structural and functional properties of the tissues.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Goldberg M,Escaig Fdoi
10.1007/BF02557834subject
Has Abstractpub_date
1985-09-01 00:00:00pages
511-8issue
5eissn
0171-967Xissn
1432-0827journal_volume
37pub_type
杂志文章abstract::Lumbar spine bone mass and density were measured with Dual photon absorptiometry (DPA) in 60 patients with crush fractures and 60 age-matched normal women. Short-term reproducibility of bone mineral density (BMD) was 1.3% in normal women and 2.5% in osteoporotic women; long-term reproducibility in normal women was 2.2...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02553274
更新日期:1988-12-01 00:00:00
abstract::The mineral in bone is located primarily within the collagen fibril, and during mineralization the fibril is formed first and then water within the fibril is replaced with mineral. Our goal is to understand the mechanism of fibril mineralization, and as a first step we recently determined the size exclusion characteri...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-007-9085-2
更新日期:2008-02-01 00:00:00
abstract::Observational studies examining associations of smoking and alcohol consumption with bone mineral density (BMD) have generated inconsistent results and suffer from several methodological limitations. We aim to evaluate whether there are causal associations between smoking, alcohol consumption, and BMD using a Mendelia...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-018-0452-y
更新日期:2018-11-01 00:00:00
abstract::The severest long-term complications of orthopedic joint-prostheses are associated with loosening of the implant-bone interface, due to adverse reactions in bone and subsequent weakening of the connection between the two materials. Mechanical stresses, caused by joint loading, play a key role in the adaption of interf...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02406143
更新日期:1984-01-01 00:00:00
abstract::Aging bone shows a progressive decline in mass and strength. Previous studies have suggested that bone marrow stem cells are reduced with aging and that this could be responsible, in part, for age-associated bone deficits. We measured the number of osteoprogenitor cells present in the bone marrow from adult and aged r...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00296343
更新日期:1995-02-01 00:00:00
abstract::Using data from the Peking Vertebral Fracture Study, we conducted a longitudinal cohort study to investigate the association between type 2 diabetes mellitus (T2DM) and the risk of incident fractures, especially of vertebral fractures (VFs), and we also examined the modifying effect of body mass index (BMI) on this as...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-019-00598-x
更新日期:2019-11-01 00:00:00
abstract::Increased bone loss has been noted in lymphoma patients; however, the incidence of hip fracture is not known. The aim of our study was to explore the risk for hip fracture in patients with lymphoma compared with the entire Swedish population. The risk of hip fracture was determined in a retrospective population cohort...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-020-00674-7
更新日期:2020-06-01 00:00:00
abstract::Impact activity is an important contributor to bone accrual. Children engaging in such activity have been shown to have greater bone mineral density (BMD) than their peers. This cross-sectional study was designed to quantify the association between BMD and impact activity in pre-pubescent girls, specifically examining...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-001-1131-x
更新日期:2003-01-01 00:00:00
abstract::This study aims to test the hypothesis that noninvasive bone mass measurements can be used to predict bone strength in a piglet model. Dual energy X-ray absorptiometry measurements of bone mineral content (BMC), bone mineral density (BMD), and bone area (BA) were obtained from four sets of bones (left and right humeri...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010006
更新日期:2001-04-01 00:00:00
abstract::Using both low microwave power and weak magnetic field modulation, we have shown that the asymmetric signal arising in X-irradiated tooth enamel as well as in A-type carbonated apatite exposed to X-rays or to excited oxygen has an orthorhombic character and must be attributed to CO2-. Effectively, the mean values foun...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02409421
更新日期:1981-01-01 00:00:00
abstract::Monoclonal antibody against bovine serum alpha 2HS glycoprotein was raised in mice and the localization of this glycoprotein in bovine and human teeth was examined by immunohistochemical techniques on undemineralized ground sections after surface etching with dilute HCl. Positive reactions were found in both bovine an...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555864
更新日期:1990-07-01 00:00:00
abstract::The drawbacks of estrogen restrict the clinical use of hormone replacement therapy, and it would be most helpful to explore new estrogenic substances that could prevent bone loss and be free from any adverse effects. We synthesized a new compound named bone-seeking estrogen (SE2) by combining 17β-estradiol (E2) with i...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-013-9739-1
更新日期:2013-08-01 00:00:00
abstract::Fourier-transform (FT) Raman spectroscopy was used to characterize the organic and mineral components of biological and synthetic calcium phosphate minerals. Raman spectroscopy provides information on biological minerals that is complimentary to more widely used infrared methodologies as some infrared-inactive vibrati...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00305529
更新日期:1994-05-01 00:00:00
abstract::We examined differences in patients' survival after hip fracture (HF) and risk for subsequent HF among patients treated with oral and intravenous bisphosphonates (oBPs, iBPs), denosumab (DMAB), and patients without therapy. We used data from all patients in Austria aged ≥ 50 who sustained a HF between 2012 and 2017 an...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-019-00611-3
更新日期:2019-12-01 00:00:00
abstract::The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9661-y
更新日期:2013-01-01 00:00:00
abstract::A continuous flow organ culture system (CFCS) was used to determine the effect of ascorbic acid on the synthesis of collagen and noncollagenous protein by bone of the alveolar process and periodontal ligament in organ cultures of adult mouse periodontium. For the last 24 h of 2 day cultures, 5 microCi/ml 3H-proline wa...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02411276
更新日期:1982-07-01 00:00:00
abstract::Mechanical forces applied to cultured bone cells induce the production of cAMP via stimulation of the formation of prostaglandin E2 (PGE2) and its release into the medium, resulting in stimulation of adenylate cyclase. In this paper we show that either the antibiotic gentamycin (100 micrograms/ml) or antiphospholipid ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02553753
更新日期:1988-04-01 00:00:00
abstract::Limited information is available on the effect of bisphosphonates in men receiving corticosteroid therapy. We studied 184 men among the patients enrolled in two, double-blind, placebo-controlled, 1-year studies with similar protocols. The studies evaluated the effects of risedronate in patients beginning corticosteroi...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00223-001-1060-8
更新日期:2001-10-01 00:00:00
abstract::The effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) (2.3 x 10(-12) - 1.4 x 10(-6) [M]) on alkaline phosphatase, collagen, and cell proliferation were examined in primary cultured hypertrophic chondrocytes prepared from the distal epiphyseal growth plate of the tibias of 12-day chick embryos. 1,25(OH)2D3 showed time-...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00296776
更新日期:1992-05-01 00:00:00
abstract::The purpose of this study was to investigate the mineral induction capacity in vitro of polyanionic proteins covalently bound to a surface. Rat dentin gamma-carboxyglutamate-containing protein of the osteocalcin type (Gla-protein), proteoglycan (PG), and phosphoprotein (PP-H), as well as phosvitin (PhV) and bovine ser...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02553763
更新日期:1989-04-01 00:00:00
abstract::The fossil record shows that bone remodeling has existed since the earliest large vertebrates became weight-bearing on land, but the functions of remodeling have long been debated. The principal protagonists in this debate have been those favoring a mechanical function and those asserting that remodeling serves to mov...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-002-1059-9
更新日期:2003-08-01 00:00:00
abstract::Icariin, the main constituent of Herba Epimedii, appears to be a promising alternative to classic drugs used to treat osteoporosis. However, the detailed molecular mechanisms of its action and the role of icariin in the cross-talk between osteoblasts and adipocytes remain unclear. The present study was designed to inv...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-016-0138-2
更新日期:2016-08-01 00:00:00
abstract::A positional cloning effort in French Canadian families with Paget's disease of bone (PDB) resulted in the identification of a mutation in the sequestosome1 (SQSTM1) gene in a subset of both familial and sporadic PDB cases. This was confirmed in samples of mainly United Kingdom (UK) origin. In this study, we performed...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-004-0244-4
更新日期:2004-08-01 00:00:00
abstract::Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223001093
更新日期:2000-07-01 00:00:00
abstract::An experimental fracture model was used to assess bone mineral density at the fracture site by peripheral computed tomography and to compare the model with biomechanical, histological, and radiographic methods for the quantification of the fracture repair process. Transverse osteotomies in the mid-diaphysis of 28 tibi...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900213
更新日期:1997-02-01 00:00:00
abstract::Vitamin D supplements are often recommended to restore sufficiency, although the adherence to treatment is low. This study assessed vitamin D status at different time intervals following the cessation of treatment. The database of Clalit-Health-Services (CHS), a not-for-profit HMO covering more than half of the Israel...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-011-9536-7
更新日期:2011-11-01 00:00:00
abstract::Tartrate resistant acid phosphatase (TRAP) has been proposed as a new biochemical marker for bone resorption. We have compared this new marker, TRAP, with the classical biochemical markers of bone remodelling, serum alkaline phosphatase (sAP), serum osteocalcin (sBGP), and with the urinary hydroxyproline/creatinine ra...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555896
更新日期:1991-07-01 00:00:00
abstract::The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02411296
更新日期:1982-01-01 00:00:00
abstract::The crystallinity of bone mineral at different stages of maturation has been measured by quantitative X-ray diffraction methods. Crystallinity measurements were made on tibial mid-diaphyses from 17-day embryonic chicks, newly-formed periosteal bone from embryonic chicks, and density-fractionated bone from post-hatch c...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405032
更新日期:1983-01-01 00:00:00
abstract::Studies suggest that long-term use of proton pump inhibitors (PPIs) may be associated with an increased risk of fracture. However, the role of medication adherence in this association is not fully understood. A retrospective cohort study was conducted to examine the relationship between PPI use/adherence and fracture ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-014-9855-6
更新日期:2014-06-01 00:00:00