Abstract:
:The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones of girls who received estrogen replacement therapy were less demineralized than those of the others. The bone mineral deficit became less pronounced with advancing age. It could not be determined if the apparent effect of estrogens was related to age or if the apparent improvement with age was really due to an effect of estrogen treatment. For 8 subjects followed longitudinally there was no significant change in the BMC deficit.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Shore RM,Chesney RW,Mazess RB,Rose PG,Bargman GJdoi
10.1007/BF02411296subject
Has Abstractpub_date
1982-01-01 00:00:00pages
519-22issue
6eissn
0171-967Xissn
1432-0827journal_volume
34pub_type
杂志文章abstract::Micro-computed tomography (microCT) has become a standard tool for the evaluation of bone morphology in preclinical studies. Unfortunately, the user-dependent definition of contour lines that separate trabecular from cortical bone is not only extremely time-consuming but may also represent a source of data bias and in...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-007-9063-8
更新日期:2007-10-01 00:00:00
abstract::As tobacco smoking has been identified as a risk factor in the development of osteoporosis, possible deleterious effects of nicotine inhalation on bone mineral density (BMD) and mechanical properties of the femur in female rats were studied. Female Sprague Dawley rats were exposed to nicotine vapour 20 hours a day 5 d...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900692
更新日期:1999-09-01 00:00:00
abstract::The effects of a series of novel phosphonates on the kinetics of mineral development in an ionophore-primed 7:2:1 phosphatidylcholine (PC): dicetylphosphate (DCP): cholesterol (Chol) liposomal model system are reported. When present at 2.5 micromol/liter or 25 micromol/liter concentrations in the solution surrounding ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02509384
更新日期:1996-05-01 00:00:00
abstract::The solubilization of alkaline phosphatase (AP) from osteoblastic cell membranes obtained from human primary bone cell cultures was studied according to the age and sex of the donors (17 females, 11 males; age range: 2-77 years). Cell membranes were treated by non-ionic (n-octyl beta-D-glucopyranoside, OG), ionic or z...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230050006
更新日期:2000-01-01 00:00:00
abstract::Total fat mass plays a significant role in determining bone mass, but the specific role of central adiposity independent of total fat mass has not been widely studied. Prepubertal (Tanner 1) children (n = 181; 65 boys, 116 girls, 7.8 +/- 1.5 years), including 99 Caucasians and 82 African Americans from Birmingham, Ala...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-006-0116-1
更新日期:2006-12-01 00:00:00
abstract::Familial hypocalciuric hypercalcemia (FHH) is often considered in the differential diagnosis of hyperparathyroidism, but is rarely diagnosed. So far, FHH has not been documented in Israel. This report presents preliminary evidence for the occurrence of FHH in Israel. ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900290
更新日期:1997-07-01 00:00:00
abstract::We analyzed the bone microarchitecture of the subcapital and basicervical subregions of the femoral neck in men, to determine whether microarchitectural differences of cortical or trabecular bone can explain differential frequency of subcapital vs. basicervical fractures, especially in aged persons. The study sample e...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-020-00717-z
更新日期:2020-09-01 00:00:00
abstract::Conventional transmission electron microscopy requires an effective dehydration of the tissue specimens under investigation. This dehydration, for which ethanol most often is used, may influence the solubility of the slightly soluble calcium phosphates. To study the behavior of calcium phosphates in ethanol, stable ne...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02554840
更新日期:1985-03-01 00:00:00
abstract::To study the risk of fractures associated with anxiolytics, sedatives, and hypnotics, we conducted a case-control study. Cases were all subjects with any fracture during the year 2000 (n = 124,655). For each case, three controls (n = 373,962) matched on age and gender were randomly drawn from the background population...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-007-9095-0
更新日期:2008-01-01 00:00:00
abstract::High impact loading is known to prevent some of the age-related bone loss but its effects on the density distribution of cortical bone are relatively unknown. This study examined the effects of age and habitual sprinting on tibial and fibular mid-shaft bone traits (structural, cortical radial and polar bone mineral de...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-014-9881-4
更新日期:2014-08-01 00:00:00
abstract::Dual photon absorptiometry (DPA) is currently the most widely used method for noninvasive bone mineral density (BMD) measurement of the axial skeleton. Dual energy X-ray absorptiometry (DEXA) is a recently developed technique that uses an X-ray tube as a photon source; it has demonstrated several significant advantage...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556250
更新日期:1991-11-01 00:00:00
abstract::ATP is as effective as inorganic pyrophosphate in retarding the rate of dissolution of calcium hydroxyapatite at pH 7, ADP is less effective, and AMP is without effect. The inhibition is due to the adsorption of ATP and ADP units on the crystal surface. ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405386
更新日期:1984-12-01 00:00:00
abstract::A continuous flow organ culture system (CFCS) was used to determine the effect of ascorbic acid on the synthesis of collagen and noncollagenous protein by bone of the alveolar process and periodontal ligament in organ cultures of adult mouse periodontium. For the last 24 h of 2 day cultures, 5 microCi/ml 3H-proline wa...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02411276
更新日期:1982-07-01 00:00:00
abstract::Magnetic resonance imaging (MRI) is commonly used in the assessment of the musculoskeletal system and associated pathology. The ability of MRI to measure the signals from water and lipid protons enables quantitative measurements of bone porosity. The goal of this investigation was to demonstrate that the density and c...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230050015
更新日期:2000-01-01 00:00:00
abstract::Sulfotransferase 1E1 (SULT1E1) catalyze estrogen into sulfate conjugation and is involved in the metabolism of phytoestrogen. A community-based cross-sectional study was conducted on 397 Korean women, to evaluate the association between genetic polymorphisms of SULT1E1 and bone mineral density (BMD) and the combined e...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-006-0008-4
更新日期:2006-09-01 00:00:00
abstract::Low-grade inflammation negatively affects bone. Resveratrol is a natural compound proven to possess both anti-inflammatory and bone protective properties. However, it is uncertain if the bone effects are mediated though anti-inflammatory effects. Firstly, we investigated if resveratrol affects proliferation and differ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-016-0130-x
更新日期:2016-08-01 00:00:00
abstract::Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of woven and lamellar bone at one or more affected skeletal sites. As a result, bone pain, noti...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-019-00522-3
更新日期:2019-05-01 00:00:00
abstract::The usefulness of various bone mineral measurement techniques is a subject of current controversy. In order to explore whether disparate conclusions may have arisen from differences in analytic methodology, data from published reports of bone mass and nonviolent fractures have been reanalyzed in terms of fracture risk...
journal_title:Calcified tissue international
pub_type: 杂志文章,meta分析
doi:10.1007/BF02555036
更新日期:1990-03-01 00:00:00
abstract::Teriparatide (TPTD) is the most widely used anabolic agent in the treatment of patients with osteoporosis although its use is restricted in many countries. A recent randomised trial confirmed that TPTD was superior to risedronate at preventing vertebral fractures over a 2-year period. There is limited information on t...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-019-00563-8
更新日期:2019-08-01 00:00:00
abstract::Osteoarthritis and sarcopenia are the most frequently described musculoskeletal disorders in older persons but the intertwining of these conditions and of their functional and cellular causes is complex. This narrative review aims to identify the links between osteoarthritis and sarcopenia described 1-in clinical stud...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-020-00703-5
更新日期:2020-09-01 00:00:00
abstract::Histomorphometric evaluation of bone formation in an intravital tetracycline-labeled skeleton of a suddenly deceased osteoporotic woman is presented. The 24 skeletal sites investigated displayed substantial regional variations which, for two out of four cortical bone dynamics and all trabecular bone dynamics, were sig...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556619
更新日期:1987-04-01 00:00:00
abstract::The aims of this study were to compare the response to therapy in disease activity in pagetic patients with and without skull involvement and the usefulness of bone markers in the evaluation of these patients. Forty patients with Paget's disease treated with tiludronate and 26 healthy controls were included. Serum tot...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-005-0247-9
更新日期:2006-07-01 00:00:00
abstract::The purpose of this study was to examine the effects of green tea extract (GTE) intake on bone structural and physiological properties, such as bone mass, trabecular bone microarchitecture, cortical bone geometry, and bone mechanical strength, in growing rats. Four-week-old male Wistar rats were divided into the follo...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-017-0358-0
更新日期:2018-03-01 00:00:00
abstract::In the past years, several epidemiological and clinical observations have underlined the importance of genetics in the pathogenesis of both female and male osteoporosis. It has been estimated that from 50 to 80% of the inter-individual variability in bone mass is genetically determined. In rare instances, osteoporosis...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-001-1049-3
更新日期:2001-10-01 00:00:00
abstract::This study examined bone density among postmenopausal Buddhist nuns and female religious followers of Buddhism in southern Taiwan and related the measurements to subjects characteristics including age, body mass, physical activity, nutrient intake, and vegetarian practice. A total of 258 postmenopausal Taiwanese veget...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/pl00005812
更新日期:1997-03-01 00:00:00
abstract::The tumor-suppressor p53 is a transcription factor that regulates a number of genes in the process of cell-cycle inhibition, apoptosis, and DNA damage. Recent studies have revealed a crucial role for p53 in bone remodeling. In our previous studies we have shown that p53 is an important regulator of osteoblast differen...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-011-9533-x
更新日期:2011-11-01 00:00:00
abstract::Matrix extracellular phosphoglycoprotein (MEPE) is an inhibitor of mineralization in situ and in cell cultures where altered expression is associated with oncogenic osteomalacia and hypophosphatemic rickets. The purpose of this study was to determine whether the intact protein or the peptide(s) originating from this p...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-009-9313-z
更新日期:2010-01-01 00:00:00
abstract::N-acetyl-beta-D-glucosaminidase (NAG) is a lysosomal enzyme predominantly located in renal proximal tubules. In idiopathic hypoparathyroidism (IHP), 100 Units of human PTH (1-34) increased urinary excretion of NAG from 0.029 +/- 0.027 to 0.173 +/- 0.035 U/lGF (p less than 0.05) in two patients before treatment and fro...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556010
更新日期:1989-12-01 00:00:00
abstract::Disturbances in mineral and bone metabolism are common in patients with chronic kidney disease (CKD), especially those undergoing dialysis. Renal osteodystrophy, which describes an alteration of bone morphology, is an important component of this systemic disorder and may explain the elevated risk of fracture which adv...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-020-00788-y
更新日期:2021-01-02 00:00:00
abstract::We studied the epidemiology of osteoporotic fractures of the proximal femur (cervical and trochanteric fractures) in residents of Barcelona, aged 45 years or over, for a 1-year period. Fractures resulting from metastases were not included. During the period of observation, a total of 1,358 patients with hip fractures ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555965
更新日期:1989-06-01 00:00:00