Skeletal demineralization in Turner's syndrome.

Abstract:

:The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones of girls who received estrogen replacement therapy were less demineralized than those of the others. The bone mineral deficit became less pronounced with advancing age. It could not be determined if the apparent effect of estrogens was related to age or if the apparent improvement with age was really due to an effect of estrogen treatment. For 8 subjects followed longitudinally there was no significant change in the BMC deficit.

journal_name

Calcif Tissue Int

authors

Shore RM,Chesney RW,Mazess RB,Rose PG,Bargman GJ

doi

10.1007/BF02411296

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

519-22

issue

6

eissn

0171-967X

issn

1432-0827

journal_volume

34

pub_type

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