Old and New Drugs for the Management of Bone Disorders in CKD.

abstract：:We assessed the relationship of bone density and microarchitecture between hand, peripheral, and axial skeletal sites using high-resolution peripheral quantitative computed tomography (HR-pQCT) and dual-energy X-ray absorptiometry (DXA) in patients with rheumatoid arthritis (RA) and which factors influence these param...

journal_title：Calcified tissue international

authors： Zhu TY,Griffith JF,Qin L,Hung VW,Fong TN,Kwok AW,Leung PC,Li EK,Tam LS

更新日期：2012-11-01 00:00:00

abstract：:Dual-photon absorptiometry (153Gd) was used to measure bone mineral of the total body and major anatomical areas. Patients with osteoporosis (male = 11, female = 18) and with renal osteodystrophy (n = 17) were significantly below (20%) normal females (n = 72) and males (n = 13) at most sites. In the osteoporotic patie...

journal_title：Calcified tissue international

authors： Mazess RB,Peppler WW,Chesney RW,Lange TA,Lindgren U,Smith E Jr

更新日期：1984-01-01 00:00:00

abstract：:Hip fracture may cause and/or complicate institutionalization. We undertook this study to define its overall prevalence among the residents of four nursing homes in Central Italy as well as its latency and impact on mobility when it occurred within institutions. We also performed a case control analysis with the aim o...

journal_title：Calcified tissue international

authors： Maggio D,Ubaldi E,Simonelli G,Cenci S,Pedone C,Cherubini A

更新日期：2001-06-01 00:00:00

abstract：:Considerable advances in oncology over recent decades have led to improved survival, while raising concerns about long-term consequences of anticancer treatments. In patients with breast or prostate malignancies, bone health is a major issue due to the high risk of bone metastases and the frequent prolonged use of hor...

journal_title：Calcified tissue international

authors： Handforth C,D'Oronzo S,Coleman R,Brown J

更新日期：2018-02-01 00:00:00

abstract：:Insulin is a potent stimulator of collagen synthesis and other osteoblastic cell functions. In various insulin-sensitive tissues, stimulation of glucose transport and glycolytic metabolism are hallmarks of insulin action and may play a role in insulin regulation of cellular function. However, the effects of insulin on...

journal_title：Calcified tissue international

authors： Ituarte EA,Halstead LR,Iida-Klein A,Ituarte HG,Hahn TJ

更新日期：1989-07-01 00:00:00

abstract：:Mice deficient in the chloride channel ClC-7, which is likely involved in acidification of the resorption lacuna, display severe osteopetrosis. To fully characterize the osteopetrotic phenotype, the phenotypes of osteoclasts and osteoblasts were evaluated. ClC-7(-/-) mice and their corresponding wild-type littermates ...

journal_title：Calcified tissue international

authors： Neutzsky-Wulff AV,Karsdal MA,Henriksen K

更新日期：2008-12-01 00:00:00

abstract：:The aim of this study was to investigate bone mineral density (BMD) and bone turnover in patients with primary knee osteoarthritis (KOA) and to compare them with generalized OA (GOA) and nonGOA patients. A total of 88 postmenopausal primary KOA patients were studied. OA was graded by using knee radiographs. BMD of the...

journal_title：Calcified tissue international

authors： Naitou K,Kushida K,Takahashi M,Ohishi T,Inoue T

更新日期：2000-05-01 00:00:00

abstract：:ELISAs for measuring the urinary excretion of collagen crosslinks and related peptides appear to show marked differences in sensitivity to anti-resorptive therapy. This presumably reflects variations in specificity of the anylate being detected in these assays, and the way in which they respond to treatment. To clarif...

journal_title：Calcified tissue international

authors： Tobias JH,Laversuch CV,Wilson N,Robins SP

更新日期：1996-11-01 00:00:00

abstract：:The purpose of this study was to ascertain whether biochemical markers of bone turnover predict bone loss. The survey was carried out in Taiji, Wakayama Prefecture, Japan. From a list of inhabitants aged 40-79 years, 400 participants (50 men and 50 women in each of four age groups) were selected randomly. Bone mineral...

journal_title：Calcified tissue international

authors： Yoshimura N,Hashimoto T,Sakata K,Morioka S,Kasamatsu T,Cooper C

更新日期：1999-09-01 00:00:00

abstract：:The potassium pyroantimonate technique was utilized for the selective subcellular localization of calcium in the mandibular condylar cartilage of 1-day-old rats. Electron dense calcium pyroantimonate precipitates were localized principally in mitochondria and at the cell membrane of the chondrocytes. In addition, smal...

journal_title：Calcified tissue international

authors： Morris DC,Appleton J

更新日期：1980-01-01 00:00:00

abstract：:This report describes a method using direct photon absorptiometry (DPA) for determination in vivo of the bone mineral content to bone width ratio (BMC/W) in the rat femur. A significant correlation was noted between measurements by DPA and whole femur dry weight and ash weight. Measurements were reproducible within re...

journal_title：Calcified tissue international

authors： Sanchez TV,Myers RC,Bond JT,Mayor GH

更新日期：1981-01-01 00:00:00

abstract：:The diphosphonates dichloromethanediphosphonate (Cl2MDP) and to a minor degree 1-hydroxyethane-1,1-diphosphonate (EDHP) increased the glycogen content in cultured cartilage cells of rabbit ear. This effect was not due to different concentrations of glucose in the medium. ...

journal_title：Calcified tissue international

authors： Felix R,Fast DK,Sallis JD,Fleisch H

更新日期：1980-01-01 00:00:00

abstract：:We separated osteoclasts from bone and observed the effect of several known and potential mediators of the control of bone resorption on their cytoplasmic motility. We already found that calcitonin (CT), a hormone that inhibits bone resorption, regularly causes complete inhibition of cytoplasmic motility, specific for...

journal_title：Calcified tissue international

authors： Chambers TJ,Dunn CJ

更新日期：1983-07-01 00:00:00

abstract：:We studied the acute phase response, including specific cytokine production, [interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor alpha(TNF alpha)] following a single dose of Aredia (disodium pamidronate) in patients with increased bone turnover and, in vitro, the role played by specific cytokines in the...

journal_title：Calcified tissue international

authors： Thiébaud D,Sauty A,Burckhardt P,Leuenberger P,Sitzler L,Green JR,Kandra A,Zieschang J,Ibarra de Palacios P

更新日期：1997-11-01 00:00:00

abstract：:Discarded tissues, like human amniotic membranes and adipose tissue, were investigated for the application of Decellularized Human Amniotic Membrane (DAM) as a viable scaffold for transplantation of Adipose-derived stromal cells (ASCs) in bone regeneration of non-healing calvarial defects in rats. Amniotic membrane wa...

journal_title：Calcified tissue international

authors： Dziedzic DSM,Francisco JC,Mogharbel BF,Irioda AC,Stricker PEF,Floriano J,de Noronha L,Abdelwahid E,Franco CRC,de Carvalho KAT

更新日期：2021-01-09 00:00:00

abstract：:The aim of this study was to evaluate bone resorption (BR) in rats by two methods: chronic 3H-tetracycline labeling (3HTC) and pyridinium crosslink excretion (PYDX), and compare the sensitivity of these markers in two age groups. Female Sprague-Dawley rats at 12-29 weeks of age ("mature", n = 12) and at 40-57 weeks of...

journal_title：Calcified tissue international

authors： Talbott SM,Chowdhury H,Shapses SA

更新日期：1999-04-01 00:00:00

abstract：:Age-related loss of skeletal muscle is associated with increased risk of functional limitation and cardiovascular (CV) mortality. In the elderly abdominal aortic calcification (AAC) can increase CV risk by altering aortic properties which may raise blood pressure and increase cardiac workload. This study investigated ...

journal_title：Calcified tissue international

authors： Rodríguez AJ,Scott D,Khan B,Khan N,Hodge A,English DR,Giles GG,Ebeling PR

更新日期：2016-10-01 00:00:00

abstract：:To test the hypothesis that the relationship between fat mass (FM) and bone mineral density (BMD) is mediated by leptin. The study involved 611 individuals aged 20-89 years who were randomly sampled from Ho Chi Minh City (Vietnam). BMD at the femoral neck (FN), lumbar spine (LS), and whole body (WB) was measured by DX...

journal_title：Calcified tissue international

authors： Ho-Pham LT,Lai TQ,Nguyen UD,Bui QV,Nguyen TV

更新日期：2017-01-01 00:00:00

abstract：:We compared the cytotoxic effects of alendronate (ALN) and incadronate (YM175) on isolated rabbit osteoclasts in vitro and on rats in vivo. In the in vitro experiment, each bisphosphonate was added to the culture of isolated osteoclasts at the final concentration of 3 x 10(-5), 3 x 10(-4), or 3 x 10(-3) M, and the amo...

journal_title：Calcified tissue international

authors： Ito M,Chokki M,Ogino Y,Satomi Y,Azuma Y,Ohta T,Kiyoki M

更新日期：1998-08-01 00:00:00

abstract：:Crouzon syndrome is a debilitating congenital disorder involving abnormal craniofacial skeletal development caused by mutations in fibroblast growth factor receptor-2 (FGFR2). Phenotypic expression in humans exhibits an autosomal dominant pattern that commonly involves premature fusion of the coronal suture (craniosyn...

journal_title：Calcified tissue international

authors： Liu J,Nam HK,Wang E,Hatch NE

更新日期：2013-05-01 00:00:00

abstract：:Bone mass increases steadily until age 20-30 years, when peak bone mass (PBM) is acquired. Nutrition plays a critical role in achievement of the optimal genetically programmed PBM, with reduction in the risk of osteoporosis later in life. Intake of nutrients can be estimated through the use of various tools; typically...

journal_title：Calcified tissue international

authors： Pampaloni B,Bartolini E,Barbieri M,Piscitelli P,Di Tanna GL,Giolli L,Brandi ML

更新日期：2013-07-01 00:00:00

abstract：:The existence of nutritional deficiency rickets among infants in sunny Riyadh was confirmed radiologically. Most of the rachitic infants were breast-fed, some received unsupplemented infant feeding formulae, and all live in an environment that is devoid of sunlight. Their mean age at the time of onset was 10.5 months....

journal_title：Calcified tissue international

authors： Elidrissy AT,Sedrani SH,Lawson DE

更新日期：1984-05-01 00:00:00

abstract：:An experimental fracture model was used to assess bone mineral density at the fracture site by peripheral computed tomography and to compare the model with biomechanical, histological, and radiographic methods for the quantification of the fracture repair process. Transverse osteotomies in the mid-diaphysis of 28 tibi...

journal_title：Calcified tissue international

authors： Augat P,Merk J,Genant HK,Claes L

更新日期：1997-02-01 00:00:00

abstract：:Icariin, the main constituent of Herba Epimedii, appears to be a promising alternative to classic drugs used to treat osteoporosis. However, the detailed molecular mechanisms of its action and the role of icariin in the cross-talk between osteoblasts and adipocytes remain unclear. The present study was designed to inv...

journal_title：Calcified tissue international

authors： Zhang D,Fong C,Jia Z,Cui L,Yao X,Yang M

更新日期：2016-08-01 00:00:00

abstract：:Undesirable changes in health-related parameters are thought to occur in retiring female athletes, but this has not been examined in longitudinal studies. The purpose of this study was to examine longitudinal changes in bone mineral density (BMD), body composition, and dietary intake in gymnasts and controls. Nonathle...

journal_title：Calcified tissue international

authors： Kudlac J,Nichols DL,Sanborn CF,DiMarco NM

更新日期：2004-12-01 00:00:00

abstract：:The purpose of this study was to determine the efficacy of using bone mineral measurements of the calcaneus to evaluate osteoporosis. Dual energy X-ray absorptiometry (DXA) of the calcaneus was compared with posteroanterior lumbar absorptiometry (DXA) and vertebral quantitative computed tomography (QCT) measurements i...

journal_title：Calcified tissue international

authors： Laval-Jeantet AM,Bergot C,Williams M,Davidson K,Laval-Jeantet M

更新日期：1995-01-01 00:00:00

abstract：:Sulfotransferase 1E1 (SULT1E1) catalyze estrogen into sulfate conjugation and is involved in the metabolism of phytoestrogen. A community-based cross-sectional study was conducted on 397 Korean women, to evaluate the association between genetic polymorphisms of SULT1E1 and bone mineral density (BMD) and the combined e...

journal_title：Calcified tissue international

authors： Lee SA,Choi JY,Shin CS,Hong YC,Chung H,Kang D

更新日期：2006-09-01 00:00:00

abstract：:Compressive strength index (CSI) of the femoral neck is a parameter that integrates the information of bone mineral density (BMD), femoral neck width (FNW), and body weight. CSI is considered to have the potential to improve the performance of assessment for hip fracture risk. However, studies on CSI have been rare. I...

journal_title：Calcified tissue international

authors： Yu N,Liu YJ,Pei Y,Zhang L,Lei S,Kothari NR,Li DY,Papasian CJ,Hamilton J,Cai JQ,Deng HW

更新日期：2010-10-01 00:00:00

abstract：:The purpose of this study was to establish the smallest dose of nasally administered salmon calcitonin (SCT) which, if given in conjunction with a previously published calcium/thiazide treatment, would be as effective as parenteral SCT in the treatment of Paget's disease of bone. Forty patients suffering from symptoma...

journal_title：Calcified tissue international

authors： Evans RA,Somers NM,Dunstan CR,Hills E,Evans M

更新日期：1991-09-01 00:00:00

abstract：:This study was conducted to determine the effectiveness of three forms of vitamin E supplements following nicotine treatment on bone histomorphometric parameters in an adult male rat model. Rats were divided into seven groups: baseline (B, killed without treatment), control (C, normal saline for 4 months), nicotine (N...

journal_title：Calcified tissue international

authors： Hermizi H,Faizah O,Ima-Nirwana S,Ahmad Nazrun S,Norazlina M

更新日期：2009-01-01 00:00:00