Quantitative assessment of experimental fracture repair by peripheral computed tomography.

abstract：:We have previously noted that a relatively large load (150 N) is required to induce a strain on the cortex of rat vertebrae similar to that induced on weight-bearing bones by normal mechanical usage. It seems unlikely that the musculature of the tail normally imposes loads of this magnitude, and this suggests that the...

journal_title：Calcified tissue international

authors： Chow JW,Jagger CJ,Chambers TJ

更新日期：1996-08-01 00:00:00

abstract：:Vitamin D3 deficient (D-) mice show a depressed inflammatory response and both inflammatory peritoneal macrophages and bone marrow polymorphonuclear leukocytes of D- mice exhibit a decreased spontaneous migration under agarose. The impaired phagocytic response of peritoneal macrophages from D- mice can be corrected by...

journal_title：Calcified tissue international

authors： Bar-Shavit Z,Noff D,Edelstein S,Meyer M,Shibolet S,Goldman R

更新日期：1981-01-01 00:00:00

abstract：:This study examined effects of bone bonding and nonbonding implants on parameters associated with matrix vesicle-mediated primary bone formation, matrix vesicle alkaline phosphatase and phospholipase A2 specific activities, and phosphatidylserine content. Tibia marrow ablation followed by implantation of KG-Cera, Mina...

journal_title：Calcified tissue international

authors： Schwartz Z,Swain LD,Marshall T,Sela J,Gross U,Amir D,Muller-Mai C,Boyan BD

更新日期：1992-12-01 00:00:00

abstract：:There are few studies of the effect of smoking on bone density in young women. The reported antiestrogenic effect of smoking could be a mechanism for a possible effect of smoking on bone. We measured bone mineral density (BMD) by dual-energy X-ray absorptiometry (whole body, proximal femur, lumbar spine), and serum le...

journal_title：Calcified tissue international

authors： Daniel M,Martin AD,Drinkwater DT

更新日期：1992-04-01 00:00:00

abstract：:It is generally accepted that bone formation is depressed during corticosteroid treatment, but the effects of glucocorticoids on bone resorption are less well characterized. We have investigated the effects of short-term treatment with high-dose oral glucocorticoids on biochemical markers of bone turnover in 20 consec...

journal_title：Calcified tissue international

authors： Bornefalk E,Dahlén I,Michaëlsson K,Ljunggren,Ljunghall S

更新日期：1998-07-01 00:00:00

abstract：:Until 2006 the only mutations known to cause osteogenesis imperfecta (OI) were in the two genes coding for type I collagen chains. These dominant mutations affecting the expression or primary sequence of collagen α1(I) and α2(I) chains account for over 90% of OI cases. Since then a growing list of mutant genes causing...

journal_title：Calcified tissue international

authors： Eyre DR,Weis MA

更新日期：2013-10-01 00:00:00

abstract：:The aim of this study was to test whether the nitric oxide (NO) donor sodium nitroprusside (SNP) has an effect on mineralization in ATDC5 cells. Mineralization in ATDC5 cell culture was induced by addition of beta-glycerophosphate or inorganic phosphate, visualized by staining precipitated calcium with an alizarin red...

journal_title：Calcified tissue international

authors： Huitema LF,Vaandrager AB,van Weeren PR,Barneveld A,Helms JB,van de Lest CH

更新日期：2006-03-01 00:00:00

abstract：:The solubilization of alkaline phosphatase (AP) from osteoblastic cell membranes obtained from human primary bone cell cultures was studied according to the age and sex of the donors (17 females, 11 males; age range: 2-77 years). Cell membranes were treated by non-ionic (n-octyl beta-D-glucopyranoside, OG), ionic or z...

journal_title：Calcified tissue international

authors： Bourrat C,Radisson J,Chavassieux P,Azzar G,Roux B,Meunier PJ

更新日期：2000-01-01 00:00:00

abstract：:Recent evidence of the occurrence of brushite in newly formed bone mineral prompted a study of the solubility properties of brushite:apatite mixtures under physiological conditions and the influence on them of pH, lactate, pyruvate, and, particularly, noncollagenous bone proteins (NCBPs). Brushite alone was surprising...

journal_title：Calcified tissue international

authors： Neuman WF,Neuman MW,Diamond AG,Menanteau J,Gibbons WS

更新日期：1982-03-01 00:00:00

abstract：:Hyperthyroidism and thyroid hormone substitutive therapy with serum iT3 in the normal range of values are known to lead to increased bone remodeling and loss of bone mass. We looked for a relationship between serum iT3 and bone metabolic or bone mass parameters in 402 euthyroid women aged 44-60. In a group of 93 preme...

journal_title：Calcified tissue international

authors： Schoutens A,Laurent E,Markowicz E,Lisart J,De Maertelaer V

更新日期：1991-08-01 00:00:00

abstract：:In the past years, several epidemiological and clinical observations have underlined the importance of genetics in the pathogenesis of both female and male osteoporosis. It has been estimated that from 50 to 80% of the inter-individual variability in bone mass is genetically determined. In rare instances, osteoporosis...

journal_title：Calcified tissue international

authors： Gennari L,Brandi ML

更新日期：2001-10-01 00:00:00

abstract：:Amelogenins, the major protein components of the enamel extracellular matrix, are postulated to be involved in controlling the elongated and oriented growth of enamel carbonated apatite crystals. In order to clarify the functional role of amelogenin during the early stage of enamel biomineralization, octacalcium phosp...

journal_title：Calcified tissue international

authors： Iijima M,Moradian-Oldak J

更新日期：2004-06-01 00:00:00

abstract：:Further insight into human tooth enamel, dense fraction (TE), has been obtained by following the change and loss of CO3(2-), OH-, structurally incorporated H2O, Cl-, and, indirectly, HPO4(2-) after TE had been heated in N2 or vacuum in the range 25-1000 degrees C. Quantitative infrared spectroscopic, lattice parameter...

journal_title：Calcified tissue international

authors： Holcomb DW,Young RA

更新日期：1980-01-01 00:00:00

abstract：:Experimental analysis with paired femurs provides the opportunity to study within-person differences in fracture type and associated structural side differences. We hypothesized that different fracture types in the hips of a subject are associated with structural asymmetry. Bone mineral density (BMD) and structural me...

journal_title：Calcified tissue international

authors： Thevenot J,Pulkkinen P,Kuhn V,Eckstein F,Jämsä T

更新日期：2010-09-01 00:00:00

abstract：:Test implant plates surgically retrieved from distal femurs of dogs were studied by Raman spectroscopy in order to characterize the bone-implant interface. The implant surface consisted of phosphate mineral, plasma sprayed on a titanium substrate. On the basis of its spectroscopic signature, the phosphate mineral of b...

journal_title：Calcified tissue international

authors： Walters MA,Blumenthal NC,Leung Y,Wang Y,Ricci JL,Spivak JM

更新日期：1991-05-01 00:00:00

abstract：:Methotrexate (MTX) is one of the most commonly prescribed drugs for autoimmune rheumatic diseases. As there is no consensus on its negative effects on bone, the purpose of this investigation was to determine the clinical spectrum of patients with stress fractures due to long-term MTX treatment (i.e., MTX osteopathy). ...

journal_title：Calcified tissue international

authors： Rolvien T,Jandl NM,Stürznickel J,Beil FT,Kötter I,Oheim R,Lohse AW,Barvencik F,Amling M

更新日期：2021-02-01 00:00:00

abstract：:The potassium pyroantimonate technique was utilized for the selective subcellular localization of calcium in the mandibular condylar cartilage of 1-day-old rats. Electron dense calcium pyroantimonate precipitates were localized principally in mitochondria and at the cell membrane of the chondrocytes. In addition, smal...

journal_title：Calcified tissue international

authors： Morris DC,Appleton J

更新日期：1980-01-01 00:00:00

abstract：:Irrespective of the method used for noninvasive bone mass determination, data comparison between different centers is a major problem as significant interunit variation may occur. We, therefore, have employed mobile densitometry units to reduce interunit variability in two large epidemiologic studies in Germany. Two c...

journal_title：Calcified tissue international

authors： Wapniarz M,Lehmann R,Randerath O,Baedeker S,John W,Klein K,Allolio B

更新日期：1994-03-01 00:00:00

abstract：:Synovial fluid basic calcium phosphate (BCP) crystals are associated with severe destructive arthropathy. BCP crystals induce the secretion of matrix-degrading enzymes such as collagenase. No prophylactic or therapeutic agents are recognized to ameliorate the cartilage damage associated with BCP deposits in joints. As...

journal_title：Calcified tissue international

authors： McCarthy GM,Mitchell PG,Cheung HS

更新日期：1993-06-01 00:00:00

abstract：:Parathyroid Hormone (PTH) stimulates calcium entry into bone cells in vitro, and this effect has been proposed to mediate the actions of PTH on bone. Using cells harvested from infant rat calvaria by collagenase digestion, we evaluated the sensitivity and specificity of this phenomenon. Calcium uptake was temperature ...

journal_title：Calcified tissue international

authors： Marcus R,Orner FB

更新日期：1980-01-01 00:00:00

abstract：:In order to assess similarities and differences in women that suffer surgical versus natural menopause, a series of bone, clinical, and biochemical parameters was assayed in a clinical sample of 35 women with surgical menopause and 112 women with natural menopause. Biochemical parameters included hormones [parathyroid...

journal_title：Calcified tissue international

authors： García-Pérez MA,Moreno-Mercer J,Tarín JJ,Cano A

更新日期：2004-02-01 00:00:00

abstract：:The small proteoglycan decorin had been localized previously at the d-band in the gap zone of collagen fibrils in nonmineralizing tissues. In bone matrix this zone is proteoglycan free and is at least in some species the place where mineralization along collagen fibrils starts. To study the metabolism of the small pro...

journal_title：Calcified tissue international

authors： Blumberg P,Brenner R,Budny S,Kresse H

更新日期：1997-06-01 00:00:00

abstract：:Long-term use of hydrochlorothiazide (HCTZ), a common diuretic agent for hypertension, has been associated with increased bone density and reduced hip fracture rates in patients. In this study, we sought to examine whether HCTZ has an anabolic effect on the proliferation of human osteoblasts (derived from either verte...

journal_title：Calcified tissue international

authors： Lau KH,Song XD,Ochi M,Wergedal JE

更新日期：1996-12-01 00:00:00

abstract：:In several studies on patients with rheumatoid arthritis, an association of bone loss with a persistently high disease activity has been found. The aim of our study was to investigate the relation between disease activity and serum levels of vitamin D metabolites, parathyroid hormone (PTH), and parameters of bone turn...

journal_title：Calcified tissue international

authors： Oelzner P,Müller A,Deschner F,Hüller M,Abendroth K,Hein G,Stein G

更新日期：1998-03-01 00:00:00

abstract：:Inorganic phosphate (P(i)) can regulate the level of skeletal alkaline phosphatase (ALP) activity in human osteoblast-like cells, but not by means of changes in transcription or release from the cell surface. The current studies were intended to determine whether (1) P(i) affected the inactivation of ALP activity in h...

journal_title：Calcified tissue international

authors： Farley JR

更新日期：1995-11-01 00:00:00

abstract：:Cytochemical staining of normal human bone cells in monolayer cultures for alkaline phosphatase (ALP) indicated that the cultures contained mixed-cell populations. Time course evaluations of the cytochemical staining revealed, in addition to the ALP-negative cell population, at least two subpopulations of ALP-positive...

journal_title：Calcified tissue international

authors： Matsuyama T,Lau KH,Wergedal JE

更新日期：1990-11-01 00:00:00

abstract：:Discarded tissues, like human amniotic membranes and adipose tissue, were investigated for the application of Decellularized Human Amniotic Membrane (DAM) as a viable scaffold for transplantation of Adipose-derived stromal cells (ASCs) in bone regeneration of non-healing calvarial defects in rats. Amniotic membrane wa...

journal_title：Calcified tissue international

authors： Dziedzic DSM,Francisco JC,Mogharbel BF,Irioda AC,Stricker PEF,Floriano J,de Noronha L,Abdelwahid E,Franco CRC,de Carvalho KAT

更新日期：2021-01-09 00:00:00

abstract：:Osteocalcin, the gamma-carboxyglutamic acid-containing protein, which is the most abundant noncollagenous protein of bone and dentin, is considered to play roles in bone formation and remodeling. It is unclear how the gamma-carboxyglutamic acid side-chains in osteocalcin coordinate to Ca2+, since the X-ray structure o...

journal_title：Calcified tissue international

authors： Mizuguchi M,Fujisawa R,Nara M,Nitta K,Kawano K

更新日期：2001-12-01 00:00:00

abstract：:Bone involvement, mainly osteoporosis but also osteosclerosis, is frequent in patients with indolent systemic mastocytosis (ISM). The recent characterization of the canonical Wnt/β-catenin pathway in the regulation of bone remodeling provided important insights for our understanding of the pathophysiology of a number ...

journal_title：Calcified tissue international

authors： Rossini M,Viapiana O,Zanotti R,Tripi G,Perbellini O,Idolazzi L,Bonifacio M,Adami S,Gatti D

更新日期：2015-05-01 00:00:00

abstract：:Quantitative trait locus analysis can be used to identify genes critically involved in biological processes. No such analysis has been applied to identifying genes that control bone fracture healing. To determine the feasibility of such an approach, healing of femur fractures was measured between C57BL/6, DBA/2, and C...

journal_title：Calcified tissue international

authors： Manigrasso MB,O'Connor JP

更新日期：2008-06-01 00:00:00