Abstract:
:ATP is as effective as inorganic pyrophosphate in retarding the rate of dissolution of calcium hydroxyapatite at pH 7, ADP is less effective, and AMP is without effect. The inhibition is due to the adsorption of ATP and ADP units on the crystal surface.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Christoffersen MR,Christoffersen Jdoi
10.1007/BF02405386subject
Has Abstractpub_date
1984-12-01 00:00:00pages
659-61issue
6eissn
0171-967Xissn
1432-0827journal_volume
36pub_type
杂志文章abstract::Osteoblast differentiation is predominantly regulated by the WNT/β-catenin signaling (canonical WNT pathway), which, together with bone morphogenetic proteins, acts as the master regulator of osteogenesis. The recent characterization of the canonical WNT pathway in the regulation of bone modeling and remodeling provid...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-013-9749-z
更新日期:2013-08-01 00:00:00
abstract::Osteoarthritis (OA) is a chronic, debilitating disease affecting millions of people worldwide. Management of OA involves pharmacological and non-pharmacological approaches. Conventional pharmacological treatments have limited efficacy and are associated with a number of side-effects, restricting the number of patients...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-020-00672-9
更新日期:2020-02-13 00:00:00
abstract::Acute spinal cord injury is associated with rapid bone loss and an increased risk of fracture. In this double-blind, randomized, placebo-controlled trial, 17 patients were followed for 1 year after administration of either 4 or 5 mg of zoledronic acid or placebo. Bone mineral density (BMD) and structural analyses of t...
journal_title:Calcified tissue international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00223-007-9012-6
更新日期:2007-05-01 00:00:00
abstract::X-linked hypophosphatemia (XLH) is a rare, inheritable disorder manifesting as rickets in children and osteomalacia in adults. While conventional medical treatment with oral phosphate and alfacalcidol is recommended in childhood, it is undecided whether adults should continue therapy. The aim of this 6-year prospectiv...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-017-0363-3
更新日期:2018-03-01 00:00:00
abstract::Effects of a single dose of 200 IU of nasal salmon calcitonin (SCT) on calcium metabolism and biochemical markers of bone turnover were investigated in 12 healthy male volunteers in a randomized, placebo-controlled, cross-over design. The nasal spray was given in the morning, and subsequently blood and urine samples w...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01320907
更新日期:1993-10-01 00:00:00
abstract::Seventy-two postmenopausal osteoporotic women having more than one nontraumatic vertebral crush fracture were studied. Thirty-six of them, aged 68.8 +/- 1.2 years (18 +/- 4 YSM-years since menopause), were treated with 100 IU/day of salmon calcitonin i.m. plus 500 mg of elemental calcium for 10 days each month. The re...
journal_title:Calcified tissue international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00298606
更新日期:1995-03-01 00:00:00
abstract::Ultrasonic methods measure properties intrinsic to bone's structure that are not necessarily dependent on bone mass. Therefore, ultrasound may prove to be a useful tool for diagnosing bone fragility and osteoporosis. The goal of this study was to determine the relationship between apparent velocity of ultrasound (AVU)...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02565132
更新日期:1991-08-01 00:00:00
abstract::Experimental analysis with paired femurs provides the opportunity to study within-person differences in fracture type and associated structural side differences. We hypothesized that different fracture types in the hips of a subject are associated with structural asymmetry. Bone mineral density (BMD) and structural me...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-010-9388-6
更新日期:2010-09-01 00:00:00
abstract::Bone turnover markers (BTMs) are widely used for the management of osteoporosis, and the premenopausal reference range is the target value for the treatment of postmenopausal osteoporosis with antiresorbing agents. Three serum BTMs (serum C-telopeptide of type I collagen [CTX], osteocalcin [OC], and N-terminal propept...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-008-9126-5
更新日期:2008-05-01 00:00:00
abstract::Histomorphometric evaluation of bone formation in an intravital tetracycline-labeled skeleton of a suddenly deceased osteoporotic woman is presented. The 24 skeletal sites investigated displayed substantial regional variations which, for two out of four cortical bone dynamics and all trabecular bone dynamics, were sig...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556619
更新日期:1987-04-01 00:00:00
abstract::Familial hypocalciuric hypercalcemia (FHH) is often considered in the differential diagnosis of hyperparathyroidism, but is rarely diagnosed. So far, FHH has not been documented in Israel. This report presents preliminary evidence for the occurrence of FHH in Israel. ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900290
更新日期:1997-07-01 00:00:00
abstract::Although radiogenic free radicals are widely used as molecular probes in biological calcified tissues, their nature and their location remain controversial. In the present study we have synthesized and irradiated apatites in which 13CO3(2-) ions substitute hydroxyl or phosphate ions in hydroxyapatite. The 13C-coupling...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Osteoporosis is commonly associated with estrogen deficiency. However, the mechanisms by which the lack of this hormone causes bone loss are poorly understood. The bone structure of the oral cavity seems to be affected by estrogen deficiency, since a delayed healing process after tooth extraction has been observed aft...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-004-0013-4
更新日期:2005-02-01 00:00:00
abstract::The aim of this study was to investigate the relation between birth weight and calcaneal bone stiffness in a large sample of Belgian, healthy, preadolescent children. Participants were 827 children (3.6-11.2 years, 51.6 % boys) from the Belgian cohort of the IDEFICS study. Birth weight was obtained using a parental qu...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9636-z
更新日期:2012-10-01 00:00:00
abstract::The influence of body mass index (BMI) on T scores for total body bone mineral content (TBBMC) and regional bone mineral content (RBMC) was studied in 186 healthy women: 100 postmenopausal, 35 perimenopausal, and 51 premenopausal. The three groups were divided by BMI >25 kg/m2 and BMI <25 kg/m2 and the postmenopausal ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900310
更新日期:1997-08-01 00:00:00
abstract::The extractions of 85Sr2+, 18F-, sucrose-14C, EDTA-51Cr, and antipyrine-14C in bone were determined by the multiple indicator-dilution method. Fluoride and strontium extractions were 18 to 70% during a single transcapillary passage, and those of EDTA and sucrose were from 11 to 59%, whereas extraction of antipyrine wa...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02407178
更新日期:1980-01-01 00:00:00
abstract::Whole enamel scrapings from unerupted teeth of embryonic calves have been separated into fractions of varying density by stepwise centrifugation in bromoform-toluene mixtures of increasing specific gravity. Partition of enamel in this manner yields individual fractions of increasing mineral phase age and maturation. W...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405006
更新日期:1983-01-01 00:00:00
abstract::We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555980
更新日期:1990-09-01 00:00:00
abstract::The potassium pyroantimonate technique was utilized for the selective subcellular localization of calcium in the mandibular condylar cartilage of 1-day-old rats. Electron dense calcium pyroantimonate precipitates were localized principally in mitochondria and at the cell membrane of the chondrocytes. In addition, smal...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02408603
更新日期:1980-01-01 00:00:00
abstract::Cytochemical staining of normal human bone cells in monolayer cultures for alkaline phosphatase (ALP) indicated that the cultures contained mixed-cell populations. Time course evaluations of the cytochemical staining revealed, in addition to the ALP-negative cell population, at least two subpopulations of ALP-positive...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555909
更新日期:1990-11-01 00:00:00
abstract::Patients put at bedrest for medical reasons lose 1-2% of spinal bone mineral per week. Losses of this magnitude during even short-term space flights of a few months would pose a serious limitation and require countermeasures. The spinal bone mineral (L2-L4) was determined in 6 healthy males (precision = 2%) before and...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555226
更新日期:1987-11-01 00:00:00
abstract::It has long been thought that collagen fibers within the bone matrix are deposited in an aligned pattern that channels mineral growth. If this model of bone structure is correct, both organic and inorganic phases of bone should have similar elastic anisotropy. Using an acoustic microscope, we measured longitudinal and...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00299319
更新日期:1994-11-01 00:00:00
abstract::TGF-beta isoforms sequestrated in dentin matrix potentially provide a reservoir of bioactive molecules that may influence cell behavior in the dentin-pulp complex following tissue injury. The association of these growth factors with dentin matrix and the influence of such associations on the bioactivity of growth fact...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-009-9248-4
更新日期:2009-07-01 00:00:00
abstract::Osteoclastic bone resorption can be induced within the auditory bulla of the Mongolian gerbil by minute increases in air pressure. The objective of this study was to determine the rate at which osteoclasts are induced in areas of resorption and to compare the rate of osteoblast recruitment. Stainless steel tubes were ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556026
更新日期:1989-11-01 00:00:00
abstract::Gallium nitrate (GaN) reduces cancer-related hypercalcemia and inhibits bone resorption in vitro. This study investigated the effects of chronic GaN administration on bone, kidney, and parathyroid gland activity of growing rats. Experimental animals received GaN (1.75 mg elemental gallium i.p. QOD X 8, Ga+), and contr...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555260
更新日期:1987-05-01 00:00:00
abstract::The accompanying article by Drs. Lian and Stein describes current thinking on how genes are organized in the nucleus and suggests that subnuclear localization is critical for the control of gene expression in bone. In particular, it is proposed that a major function of the osteoblast transcription factor, Runx2, is to...
journal_title:Calcified tissue international
pub_type: 评论,杂志文章,评审
doi:10.1007/s00223-002-1053-2
更新日期:2003-06-01 00:00:00
abstract::Fracture healing is a natural process that recapitulates embryonic skeletal development. In the early phase after fracture, reactive oxygen species (ROS) are produced under inflammatory and ischemic conditions due to vessel injury and soft tissue damage, leading to cell death. Usually, such damage during the course of...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-019-00576-3
更新日期:2019-10-01 00:00:00
abstract::There is still controversy over the impact of diabetes control and duration on bone mass and growth parameters in children and adolescents with insulin-dependent diabetes mellitus (IDDM). The aim of this study was to assess bone mineral density (BMD) at axial and appendicular sites, in children with noncomplicated IDD...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900390
更新日期:1998-01-01 00:00:00
abstract::During endochondral ossification, proliferative activity of chondrocytes is arrested and the cells undergo terminal hypertrophic differentiation. We examined the expression of the cyclin-dependent kinase inhibitor, p21(CIP1/WAF1) in permanent cartilage (xyphoid and articular cartilage) and in cartilage undergoing endo...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900323
更新日期:1997-09-01 00:00:00
abstract::As tobacco smoking has been identified as a risk factor in the development of osteoporosis, possible deleterious effects of nicotine inhalation on bone mineral density (BMD) and mechanical properties of the femur in female rats were studied. Female Sprague Dawley rats were exposed to nicotine vapour 20 hours a day 5 d...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900692
更新日期:1999-09-01 00:00:00