Spinal bone mineral after 5 weeks of bed rest.

Abstract:

:Patients put at bedrest for medical reasons lose 1-2% of spinal bone mineral per week. Losses of this magnitude during even short-term space flights of a few months would pose a serious limitation and require countermeasures. The spinal bone mineral (L2-L4) was determined in 6 healthy males (precision = 2%) before and after 5 weeks of complete bed rest. Only one individual had a significant loss (3%) and the -0.9% mean change for the 6, was not significant (P = 0.06). The average negative calcium balance during the 5 weeks was 4 g or 0.36% of total body calcium, similar to that reported in other bed-rest studies. Spinal bone loss, however, in healthy bed-rested males is significantly less than reported for bed-rested patients, suggesting that a large loss of spinal bone mineral does not occur during space flight missions lasting 5 weeks or less.

journal_name

Calcif Tissue Int

authors

LeBlanc A,Schneider V,Krebs J,Evans H,Jhingran S,Johnson P

doi

10.1007/BF02555226

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

259-61

issue

5

eissn

0171-967X

issn

1432-0827

journal_volume

41

pub_type

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