Effects of Collagen Crosslinking on Bone Material Properties in Health and Disease.

abstract：:Thyroxine (T4), triiodothyronine (T3), and alkaline phosphatase (AP) were assayed monthly in white-tailed deer plasma obtained from the antler (A), jugular (J), and the saphenous (S) veins during the period of antler growth and the period of mineralization. The concentrations of T3, T4, and AP in the J and S were not ...

journal_title：Calcified tissue international

authors： Bubenik GA,Sempere AJ,Hamr J

更新日期：1987-07-01 00:00:00

abstract：:The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...

journal_title：Calcified tissue international

authors： Heervä E,Leinonen P,Kuorilehto T,Peltonen S,Pöyhönen M,Väänänen K,Peltonen J

更新日期：2013-01-01 00:00:00

abstract：:Bone involvement is one of the most disabling aspects of type I Gaucher disease and its pathophysiology is still not well understood. As an invasive procedure, bone biopsies are not appropriate in a large population study. The development of sensitive bone resorption and formation tests have allowed the authors to stu...

journal_title：Calcified tissue international

authors： Ciana G,Martini C,Leopaldi A,Tamaro G,Katouzian F,Ronfani L,Bembi B

更新日期：2003-03-01 00:00:00

abstract：:Octacalcium phosphate (Ca8H2(PO4)6 . 5H2O) is considered to be precursor in the formation of apatite in bones and teeth; a crucial step for incorporation of impurities appears to occur during its hydrolysis. The present study examines the role that octacalcium phosphate plays in the process of incorporation of carbona...

journal_title：Calcified tissue international

authors： Chickerur NS,Tung MS,Brown WE

更新日期：1980-01-01 00:00:00

abstract：:The present study examined calcium phosphate precipitation in aqueous suspensions of multilamellar liposomes as a possible in vitro model for matrix vesicle mineralization. Liposomes were prepared by dispersing CHCl3-evaporated thin films of 7:2:1 and 7:1:1 molar mixtures of phosphatidylcholine, dicetyl phosphate, and...

journal_title：Calcified tissue international

authors： Eanes ED,Hailer AW,Costa JL

更新日期：1984-07-01 00:00:00

abstract：:Ipriflavone (i.p.) positively affects bone density in postmenopausal osteoporosis, primarily by inhibiting bone resorption. Using in vitro models of human osteoblast differentiation, we have observed that i.p. and some of its metabolites stimulate the expression of bone sialoprotein, decorin, and type I collagen, and ...

journal_title：Calcified tissue international

authors： Civitelli R

更新日期：1997-01-01 00:00:00

abstract：:The ability of 1,25(OH)2D3 and of 24,25(OH)2D3 to prevent or to heal rickets in chicks was evaluated by studies of plasma biochemistry, growth plate histology, bone morphometry and microradiography, and bone mineralization. 1,25(OH)2D3 at a dose of 100 ng/day produced fewest abnormalities compared with vitamin D3-trea...

journal_title：Calcified tissue international

authors： Dickson IR,Hall AK,Jande SS

更新日期：1984-01-01 00:00:00

abstract：:Mandibular first molars of 17-day-old mouse embryos were cultured in vitro to examine the histological effects of various concentrations of parathyroid hormone (PTH) on odontogenesis of the molars. PTH did not affect the cytodifferentiation of mesenchymal cells into preodontoblasts but inhibited that of preodontoblast...

journal_title：Calcified tissue international

authors： Sakakura Y

更新日期：1987-01-01 00:00:00

abstract：:Polymorphisms in the region of the gene for the vitamin D receptor (VDR) (chromosome 12q12-14) have been associated with differences in bone mineral density (BMD) in some studies but not in others. Because linkage analysis assesses allele sharing identical-by-descent among relatives instead of the association of a par...

journal_title：Calcified tissue international

authors： Zee RY,Myers RH,Hannan MT,Wilson PW,Ordovas JM,Schaefer EJ,Lindpaintner K,Kiel DP

更新日期：2000-12-01 00:00:00

abstract：:Matrix extracellular phosphoglycoprotein (MEPE) is an inhibitor of mineralization in situ and in cell cultures where altered expression is associated with oncogenic osteomalacia and hypophosphatemic rickets. The purpose of this study was to determine whether the intact protein or the peptide(s) originating from this p...

journal_title：Calcified tissue international

authors： Boskey AL,Chiang P,Fermanis A,Brown J,Taleb H,David V,Rowe PS

更新日期：2010-01-01 00:00:00

abstract：:We examined differences in patients' survival after hip fracture (HF) and risk for subsequent HF among patients treated with oral and intravenous bisphosphonates (oBPs, iBPs), denosumab (DMAB), and patients without therapy. We used data from all patients in Austria aged ≥ 50 who sustained a HF between 2012 and 2017 an...

journal_title：Calcified tissue international

authors： Behanova M,Reichardt B,Stamm TA,Zwerina J,Klaushofer K,Kocijan R

更新日期：2019-12-01 00:00:00

abstract：:We treated four hypercalcemic cancer patients by nasal hCT, 3 x 2 mg daily, which has been reported to be active in Paget's disease at lower doses. Only one patient became normocalcemic and mean (+/- SEM) calcium levels fell from 11.6 +/- 0.2 mg/dl before therapy to 10.7 +/- 0.6 mg/dl 2-3 days after starting hCT. The ...

journal_title：Calcified tissue international

authors： Dumon JC,Magritte A,Body JJ

更新日期：1992-07-01 00:00:00

abstract：:Bone loss during advancing age in women and men is partly the result of sex steroid deficiency. As the contribution of circulating sex steroids and sex hormone-binding globulin (SHBG) to bone loss remains uncertain, we sought to determine whether levels of sex steroids or SHBG predict change in bone mineral density (B...

journal_title：Calcified tissue international

authors： Bjørnerem A,Emaus N,Berntsen GK,Joakimsen RM,Fønnebø V,Wilsgaard T,Oian P,Seeman E,Straume B

更新日期：2007-08-01 00:00:00

abstract：:Cost-effective intervention thresholds (ITs) based on FRAX(®) were determined for Portugal. Assuming a willingness to pay (WTP) of €32,000 per quality-adjusted life years (QALYs), treatment with generic alendronate is cost effective for men and women aged 50 years or more, with 10-year probabilities for major osteopor...

journal_title：Calcified tissue international

authors： Marques A,Lourenço Ó,Ortsäter G,Borgström F,Kanis JA,da Silva JA

更新日期：2016-08-01 00:00:00

abstract：:We had shown that aromatic amino acid (phenylalanine, tyrosine, and tryptophan) supplementation prevented bone loss in an aging C57BL/6 mice model. In vivo results from the markers of bone breakdown suggested an inhibition of osteoclastic activity or differentiation. To assess osteoclastic differentiation, we examined...

journal_title：Calcified tissue international

authors： Refaey ME,Zhong Q,Ding KH,Shi XM,Xu J,Bollag WB,Hill WD,Chutkan N,Robbins R,Nadeau H,Johnson M,Hamrick MW,Isales CM

更新日期：2014-08-01 00:00:00

abstract：:The purpose of this study is to estimate the efficacy of eldecalcitol (1α, 25-Dihydroxy-2β- (3-hydroxypropyloxy) vitamin D3; ELD) on bone metabolism after long-term administration. Six-month-old Wistar-Imamichi rats were ovariectomized (OVX) and administered ELD orally at doses of 7.5, 15, or 30 ng/kg daily. Bone mine...

journal_title：Calcified tissue international

authors： Takeda S,Smith SY,Tamura T,Saito H,Takahashi F,Samadfam R,Haile S,Doyle N,Endo K

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to test whether the nitric oxide (NO) donor sodium nitroprusside (SNP) has an effect on mineralization in ATDC5 cells. Mineralization in ATDC5 cell culture was induced by addition of beta-glycerophosphate or inorganic phosphate, visualized by staining precipitated calcium with an alizarin red...

journal_title：Calcified tissue international

authors： Huitema LF,Vaandrager AB,van Weeren PR,Barneveld A,Helms JB,van de Lest CH

更新日期：2006-03-01 00:00:00

abstract：:Relapse after orthodontic tooth movement is a significant problem in orthodontics. The purpose of this study was to examine the efficacy of the osteoclast inhibitor osteoprotegerin-Fc (OPG-Fc) for inhibiting postorthodontic relapse. Rat maxillary molars were moved mesially and allowed to relapse for 24 days. Low-dose ...

journal_title：Calcified tissue international

authors： Hudson JB,Hatch N,Hayami T,Shin JM,Stolina M,Kostenuik PJ,Kapila S

更新日期：2012-04-01 00:00:00

abstract：:Vascular calcification (VC), which is associated with high cardiovascular morbidity and mortality in patients with chronic kidney disease, is promoted by the osteoblastic differentiation of vascular smooth muscle cells (VSMCs). The present study explored the functional roles and molecular mechanisms of the long noncod...

journal_title：Calcified tissue international

authors： Chang Z,Yan G,Zheng J,Liu Z

更新日期：2020-07-01 00:00:00

abstract：:We have recently reported that risedronate preserves normal bone formation and decreases bone remodeling in women with postmenopausal osteoporosis after 3 years of treatment. We report now the results of a 2-year extension study. The primary objective of this study was to determine the effect of 5 years of risedronate...

journal_title：Calcified tissue international

authors： Ste-Marie LG,Sod E,Johnson T,Chines A

更新日期：2004-12-01 00:00:00

abstract：:Biochemical markers applicable to the ovariectomized rat model can provide important tools for studying the bone remodeling process in this animal model of postmenopausal osteoporosis. We describe the development and application of two biochemical markers, a C-telopeptide (of type-I collagen) enzyme-linked immunosorbe...

journal_title：Calcified tissue international

authors： Srivastava AK,Bhattacharyya S,Castillo G,Wergedal J,Mohan S,Baylink DJ

更新日期：2000-06-01 00:00:00

abstract：:It is our hypothesis that interstitial fluid flow plays a role in the bone remodeling response to mechanical loading. The fluid flow-induced expression of three proteins (collagen, osteopontin, and alkaline phosphatase) involved in bone remodeling was investigated. Rat calvarial osteoblasts subjected to pulsatile flui...

journal_title：Calcified tissue international

authors： Hillsley MV,Frangos JA

更新日期：1997-01-01 00:00:00

abstract：:To study the mechanism of action of thyroid hormones on bone, we examined the effects of immunosuppressive and nonimmunosuppressive cyclosporins, as well as of transforming growth factor beta 1 (TGF beta 1), 17 beta-estradiol (E2), and dihydroxytestosterone (DHT) on thyroxine (T4)- and triiodothyronine (T3)-stimulated...

journal_title：Calcified tissue international

authors： Lakatos P,Stern PH

更新日期：1992-02-01 00:00:00

abstract：:We compared the effects of four vitamin D metabolites, 1 alpha,25 dihydroxy vitamin D3 (1 alpha,25(OH)2D3), 1 alpha hydroxy vitamin D3 (1 alpha OH D3), 25 hydroxy vitamin D3 (25 OH D3), and 24R,25 dihydroxy vitamin D (24R,25(OH)sD3) on resorption and collagen synthesis in fetal rat bone maintained in organ culture. Re...

journal_title：Calcified tissue international

authors： Raisz LG,Kream BE,Smith MD,Simmons HA

更新日期：1980-01-01 00:00:00

abstract：:The potassium pyroantimonate technique was utilized for the selective subcellular localization of calcium in the mandibular condylar cartilage of 1-day-old rats. Electron dense calcium pyroantimonate precipitates were localized principally in mitochondria and at the cell membrane of the chondrocytes. In addition, smal...

journal_title：Calcified tissue international

authors： Morris DC,Appleton J

更新日期：1980-01-01 00:00:00

abstract：:The native human parathyroid hormone, hPTH-(1-84), and certain carboxyl truncated analogs such as hPTH-(1-34) and even smaller fragments such as hPTH-(1-31)NH2, [Leu27]cyclo(Glu22-Lys26)hPTH-(1-31)NH2, and hPTH-(1-30)NH2 stimulate femoral trabecular and cortical bone growth in ovariectomized (OVX) rats. Here we show t...

journal_title：Calcified tissue international

authors： Whitfield JF,Morley P,Fraher L,Hodsman AB,Holdsworth DW,Watson PH,Willick GE,Barbier JR,Gulam M,Isaacs RJ,MacLean S,Ross V

更新日期：2000-04-01 00:00:00

abstract：:The phorbol ester 12-O-tetradecanoyl-13-acetate (TPA) blocked the growth of, and induced the appearance of processes in the human osteosarcoma cell line U-2 OS. The phorbol ester decreased the intracellular level of alkaline phosphatase (APase) activity (as measured per mg cell protein) and caused a marked increase in...

journal_title：Calcified tissue international

authors： Ringbom-Anderson T,Akerman KE

更新日期：1992-06-01 00:00:00

abstract：:The perilacunar areas of low mineral density in microradiographs from cortical bone of patients with hypophosphatemic (vitamin D-resistant) rickets are not evenly distributed throughout the bone tissue. Their frequency and distribution were determined in bone from 9 patients with this disease. It was found that the le...

journal_title：Calcified tissue international

authors： Choufoer JH,Steendijk R

更新日期：1979-04-17 00:00:00

abstract：:The evidence now strongly supports a central role for oestrogen in the maintenance of the normal female skeleton. Loss of endogenous oestrogen leads to a period of accelerated bone loss which can be prevented with appropriate oestrogen replacement. The route of administration is not important provided adequate dosages...

journal_title：Calcified tissue international

authors： Hillard TC,Stevenson JC

更新日期：1991-01-01 00:00:00

abstract：:The aim of this study was to determine whether forearm bone mineral density (BMD) measurements are affected by clinical risk factors for osteoporosis to the same extent as spine and hip BMD. The study population consisted of 1,009 female patients and volunteers, of whom 238 were premenopausal. Women were placed into s...

journal_title：Calcified tissue international

authors： Patel R,Blake GM,Fogelman I

更新日期：2007-02-01 00:00:00