Abstract:
:Whole enamel scrapings from unerupted teeth of embryonic calves have been separated into fractions of varying density by stepwise centrifugation in bromoform-toluene mixtures of increasing specific gravity. Partition of enamel in this manner yields individual fractions of increasing mineral phase age and maturation. Whole scrapings and isolated fractions of the fetal bovine enamel were examined by X-ray powder diffraction, scanning electron microscopy, and atomic absorption and infrared spectroscopy to determine time-related changes in the physiochemical nature of the constituent mineral phase particles. These analyses showed poorly crystalline hydroxyapatite (HA) as the only detectable solid phase of calcium phosphate present in all fractions, its degree of crystallinity increasing with increasing density. Molar Ca/P ratios and magnesium content were highest in lowest density fractions. Carbonate vibration bands at 875 and 1420-1450 cm-1, common to mineralized tissue, were observed in intermediate and higher density fractions and in whole unfractionated enamel. Another carbonate band at approximately 705 cm-1, unusual to vertebrate calcified tissue, was detected in low density fractions and disappeared rapidly with increasing enamel maturation. Its precise relation with the enamel mineral phase has not been determined.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Landis WJ,Navarro Mdoi
10.1007/BF02405006subject
Has Abstractpub_date
1983-01-01 00:00:00pages
48-55issue
1eissn
0171-967Xissn
1432-0827journal_volume
35pub_type
杂志文章abstract::The protein components of biomineralized structures (matrix proteins) are believed to modulate crystal nucleation and growth, and thereby influence the shape and strength of the final structure. The chicken eggshell contains a complex array of distinct matrix proteins. The most abundant of these was purified to homoge...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00298593
更新日期:1995-06-01 00:00:00
abstract::Ipriflavone (i.p.) positively affects bone density in postmenopausal osteoporosis, primarily by inhibiting bone resorption. Using in vitro models of human osteoblast differentiation, we have observed that i.p. and some of its metabolites stimulate the expression of bone sialoprotein, decorin, and type I collagen, and ...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s002239900378
更新日期:1997-01-01 00:00:00
abstract::To study the risk of fractures associated with anxiolytics, sedatives, and hypnotics, we conducted a case-control study. Cases were all subjects with any fracture during the year 2000 (n = 124,655). For each case, three controls (n = 373,962) matched on age and gender were randomly drawn from the background population...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-007-9095-0
更新日期:2008-01-01 00:00:00
abstract::The aim of this study was to evaluate the association among phalangeal morphometric parameters, amplitude-dependent speed of sound (AD-SOS), ultrasound bone profile index (UBPI), and spinal bone mineral density (BMD) and fracture status. One hundred women (controls, mean age 53 +/- 12 years) and 40 osteoporotic women ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-001-1092-0
更新日期:2003-04-01 00:00:00
abstract::Irrespective of the method used for noninvasive bone mass determination, data comparison between different centers is a major problem as significant interunit variation may occur. We, therefore, have employed mobile densitometry units to reduce interunit variability in two large epidemiologic studies in Germany. Two c...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00301682
更新日期:1994-03-01 00:00:00
abstract::The influence of body mass index (BMI) on T scores for total body bone mineral content (TBBMC) and regional bone mineral content (RBMC) was studied in 186 healthy women: 100 postmenopausal, 35 perimenopausal, and 51 premenopausal. The three groups were divided by BMI >25 kg/m2 and BMI <25 kg/m2 and the postmenopausal ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900310
更新日期:1997-08-01 00:00:00
abstract::Raf-1, the product of proto-oncogene c-raf-1, has key roles in the signal transduction pathways within the cell. The molecular mechanisms of tooth development in the mouse embryo are not known in detail. We examined the expression of Raf-1 during subsequent tooth development by immunohistochemical analysis. In mouse e...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02509547
更新日期:1996-01-01 00:00:00
abstract::The purpose of this study was to examine the influence of exercise on the serum concentrations of intact parathyroid hormone (PTH). Serum PTH and plasma lactate were measured in 15 well-trained men, 9 long-distance runners and 6 fire-fighters, during two running exercises. Test one consisted of 40-minute treadmill run...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00295947
更新日期:1994-04-01 00:00:00
abstract::To determine the relationships among nutrients intake, bone mass, and bone turnover in women we have investigated these issues in a population-based, cross-sectional, observational study in one county in central Sweden. A total of 175 women aged 28-74 at entry to the study were included. Dietary assessment was made by...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00298425
更新日期:1995-08-01 00:00:00
abstract::High PTH levels increase bone turnover and decrease bone mineral density (BMD). Low plasma 25-hydroxyvitamin D (25OHD) levels cause secondary hyperparathyroidism, but the relative contribution of low 25OHD and high PTH levels on risk of fracture is largely unknown. Within the cohort of women (n = 2,016) included in th...
journal_title:Calcified tissue international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00223-010-9454-0
更新日期:2011-03-01 00:00:00
abstract::N-acetyl-beta-D-glucosaminidase (NAG) is a lysosomal enzyme predominantly located in renal proximal tubules. In idiopathic hypoparathyroidism (IHP), 100 Units of human PTH (1-34) increased urinary excretion of NAG from 0.029 +/- 0.027 to 0.173 +/- 0.035 U/lGF (p less than 0.05) in two patients before treatment and fro...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556010
更新日期:1989-12-01 00:00:00
abstract::Quantitative ultrasound measurement (QUS) and bone mineral density (BMD) have each been shown to predict fracture risk in women. The present study examined whether a combination of QUS and BMD could improve the predictive accuracy of fracture risk. This is a population-based prospective study which involved 454 women ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-011-9556-3
更新日期:2012-02-01 00:00:00
abstract::Increased bone loss has been noted in lymphoma patients; however, the incidence of hip fracture is not known. The aim of our study was to explore the risk for hip fracture in patients with lymphoma compared with the entire Swedish population. The risk of hip fracture was determined in a retrospective population cohort...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-020-00674-7
更新日期:2020-06-01 00:00:00
abstract::The mineral in bone is located primarily within the collagen fibril, and during mineralization the fibril is formed first and then water within the fibril is replaced with mineral. Our goal is to understand the mechanism of fibril mineralization, and as a first step we recently determined the size exclusion characteri...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-007-9085-2
更新日期:2008-02-01 00:00:00
abstract::Relapse after orthodontic tooth movement is a significant problem in orthodontics. The purpose of this study was to examine the efficacy of the osteoclast inhibitor osteoprotegerin-Fc (OPG-Fc) for inhibiting postorthodontic relapse. Rat maxillary molars were moved mesially and allowed to relapse for 24 days. Low-dose ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9579-4
更新日期:2012-04-01 00:00:00
abstract::There is considerable interest in determining whether hypergravity can be used as a countermeasure for microgravity-induced bone loss. This study was conducted on 20 immature male rats in order to investigate possible elastic adaptations of cortical bone in rapidly growing rats exposed to chronic hypergravity. Ten rat...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900111
更新日期:1996-09-01 00:00:00
abstract::In this cross-sectional study, 91 healthy premenopausal women aged 20-39 years were investigated to determine the effect of physical activities during their teenage years on their current bone mineral densities (BMD). We measured whole-body BMD (WBMD), lumbar BMD (LBMD), and radial BMD (RBMD) with dual energy X-ray ab...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02684999
更新日期:2001-01-01 00:00:00
abstract::Using data from the Peking Vertebral Fracture Study, we conducted a longitudinal cohort study to investigate the association between type 2 diabetes mellitus (T2DM) and the risk of incident fractures, especially of vertebral fractures (VFs), and we also examined the modifying effect of body mass index (BMI) on this as...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-019-00598-x
更新日期:2019-11-01 00:00:00
abstract::Macroporous biphasic calcium phosphate (MBCP) blocks were implanted into rabbit trabecular bone and muscle, recovered 18 weeks later, and then observed and analyzed by transmission electron microscopy (TEM), electron diffraction, and electron microprobes. The results showed that (1) apatitic microcrystals appeared by ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/pl00005825
更新日期:1999-05-01 00:00:00
abstract::The usefulness of various bone mineral measurement techniques is a subject of current controversy. In order to explore whether disparate conclusions may have arisen from differences in analytic methodology, data from published reports of bone mass and nonviolent fractures have been reanalyzed in terms of fracture risk...
journal_title:Calcified tissue international
pub_type: 杂志文章,meta分析
doi:10.1007/BF02555036
更新日期:1990-03-01 00:00:00
abstract::We examined differences in patients' survival after hip fracture (HF) and risk for subsequent HF among patients treated with oral and intravenous bisphosphonates (oBPs, iBPs), denosumab (DMAB), and patients without therapy. We used data from all patients in Austria aged ≥ 50 who sustained a HF between 2012 and 2017 an...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-019-00611-3
更新日期:2019-12-01 00:00:00
abstract::Parathyroid hormone (PTH), hPTH-(1-84), and its hPTH-(1-34), hPTH-(1-31)NH2, and hPTH-(1-30)NH2 fragments reduced the tail artery pressure in anesthetized female Sprague-Dawley rats by 42.4-67.1% within about 1 minute after injection into a femoral vein, but reduced the pressure by only 8.5-36.2% 2-19 minutes after su...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900233
更新日期:1997-03-01 00:00:00
abstract::Allogenous demineralized bone matrix (DBM) represents a potential scaffold for bone tissue engineering due to its close relation in structure and function with autologous bone, but its supply is often restricted by donor availability. Thus, an expanded source of human bone is needed. The aim of this study was to evalu...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-008-9159-9
更新日期:2008-09-01 00:00:00
abstract::Polymorphisms in the region of the gene for the vitamin D receptor (VDR) (chromosome 12q12-14) have been associated with differences in bone mineral density (BMD) in some studies but not in others. Because linkage analysis assesses allele sharing identical-by-descent among relatives instead of the association of a par...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230001175
更新日期:2000-12-01 00:00:00
abstract::A simple method for determining histamine and polyamines in various tissues was devised. The method, however, could not be applied to calcified tissues, because the high concentration of Ca2+ in the extract interferes with the chromatographic separation of these amines. By treating the extracts from calcified tissues ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00296220
更新日期:1992-07-01 00:00:00
abstract::Monoclonal antibody against bovine serum alpha 2HS glycoprotein was raised in mice and the localization of this glycoprotein in bovine and human teeth was examined by immunohistochemical techniques on undemineralized ground sections after surface etching with dilute HCl. Positive reactions were found in both bovine an...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555864
更新日期:1990-07-01 00:00:00
abstract::This study was conducted to determine the effectiveness of three forms of vitamin E supplements following nicotine treatment on bone histomorphometric parameters in an adult male rat model. Rats were divided into seven groups: baseline (B, killed without treatment), control (C, normal saline for 4 months), nicotine (N...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-008-9190-x
更新日期:2009-01-01 00:00:00
abstract::TGF-beta isoforms sequestrated in dentin matrix potentially provide a reservoir of bioactive molecules that may influence cell behavior in the dentin-pulp complex following tissue injury. The association of these growth factors with dentin matrix and the influence of such associations on the bioactivity of growth fact...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-009-9248-4
更新日期:2009-07-01 00:00:00
abstract::Disturbances in mineral and bone metabolism are common in patients with chronic kidney disease (CKD), especially those undergoing dialysis. Renal osteodystrophy, which describes an alteration of bone morphology, is an important component of this systemic disorder and may explain the elevated risk of fracture which adv...
journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-020-00788-y
更新日期:2021-01-02 00:00:00
abstract::It has been well established that bone morphogenetic protein-2 (BMP-2) can induce bone formation bothin vivo andin vitro, although high concentrations (up to milligrams) of BMP-2 have been required to achieve this effectin vivo. Further, clinical applications are usually limited to a single dose at the time of implant...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02678146
更新日期:2001-02-01 00:00:00