Treatment with zoledronic acid ameliorates negative geometric changes in the proximal femur following acute spinal cord injury.

abstract：:The protein components of biomineralized structures (matrix proteins) are believed to modulate crystal nucleation and growth, and thereby influence the shape and strength of the final structure. The chicken eggshell contains a complex array of distinct matrix proteins. The most abundant of these was purified to homoge...

journal_title：Calcified tissue international

authors： Hincke MT,Tsang CP,Courtney M,Hill V,Narbaitz R

更新日期：1995-06-01 00:00:00

abstract：:As the correlation of bone mass from childhood to adulthood is unclear, we conducted a long-term prospective observational study to determine if a pediatric bone mass scan could predict adult bone mass. We measured cortical bone mineral content (BMC [g]), bone mineral density (BMD [g/cm(2)]), and bone width (cm) in th...

journal_title：Calcified tissue international

authors： Buttazzoni C,Rosengren BE,Tveit M,Landin L,Nilsson JÅ,Karlsson MK

更新日期：2014-02-01 00:00:00

abstract：:Raman spectroscopy has been used to demonstrate, for the first time, that calcium mineralization in the core of the major lateral teeth of the chiton Acanthopleura echinata takes place as an ordered process, with crystalline carbonated apatite being the first mineral deposited. Deposition begins at the top of the toot...

journal_title：Calcified tissue international

authors： Lee AP,Brooker LR,Macey DJ,van Bronswijk W,Webb J

更新日期：2000-11-01 00:00:00

abstract：:Crouzon syndrome is a debilitating congenital disorder involving abnormal craniofacial skeletal development caused by mutations in fibroblast growth factor receptor-2 (FGFR2). Phenotypic expression in humans exhibits an autosomal dominant pattern that commonly involves premature fusion of the coronal suture (craniosyn...

journal_title：Calcified tissue international

authors： Liu J,Nam HK,Wang E,Hatch NE

更新日期：2013-05-01 00:00:00

abstract：:SUMMARY. The high variation often observed in the ex vivo fibroblastic-colony forming unit (CFU-f) assay is likely to be due to both biological and experimental variation. To determine whether we could improve experimental methods we developed an alternative method of bone marrow cell (BMC) isolation employing a centr...

journal_title：Calcified tissue international

authors： Dobson KR,Reading L,Haberey M,Marine X,Scutt A

更新日期：1999-11-01 00:00:00

abstract：:The mechanism whereby liposomal entrapment enhances the hypocalcemic effect of calcitonin (CT) was evaluated in the rat. Phosphatidylcholine (PC) and PC plus cholesterol (PCC) preparations of large multilammelar vesicles (MLV) and small unilammelar vesicles (SUV) were used to entrap human calcitonin (hCT). The effect ...

journal_title：Calcified tissue international

authors： Fukunaga M,Miller MM,Deftos LJ

更新日期：1990-12-01 00:00:00

abstract：:We describe here the activity of a novel selective estrogen receptor modulator, SP500263. When given to adult ovariectomized (OVX) rats for 28 days at doses of 0.3, 1, or 3 mg/kg/day, we found that SP500263 partially protected against OVX-induced loss of bone mineral content in the distal ends of femurs and in the who...

journal_title：Calcified tissue international

authors： Sutherland MK,Brady H,Gayo-Fung LM,Leisten J,Lipps SG,McKie JA,O'Leary E,Patnaik N,Anderson DW,Bhagwat SS,Stein B

更新日期：2003-06-01 00:00:00

abstract：:The developing mandibular condylar growth center consists of a number of histologically distinct cell types. There is an increase in cell volume that takes place from the condylar surface layer through the center of ossification, resulting in a disorganized, irregular cellular pattern. Consequently, the isolation and ...

journal_title：Calcified tissue international

authors： Landesberg R,Proctor RL,Rosier RN,Puzas JE

更新日期：1995-01-01 00:00:00

abstract：:We compared the cytotoxic effects of alendronate (ALN) and incadronate (YM175) on isolated rabbit osteoclasts in vitro and on rats in vivo. In the in vitro experiment, each bisphosphonate was added to the culture of isolated osteoclasts at the final concentration of 3 x 10(-5), 3 x 10(-4), or 3 x 10(-3) M, and the amo...

journal_title：Calcified tissue international

authors： Ito M,Chokki M,Ogino Y,Satomi Y,Azuma Y,Ohta T,Kiyoki M

更新日期：1998-08-01 00:00:00

abstract：:Effects of a single dose of 200 IU of nasal salmon calcitonin (SCT) on calcium metabolism and biochemical markers of bone turnover were investigated in 12 healthy male volunteers in a randomized, placebo-controlled, cross-over design. The nasal spray was given in the morning, and subsequently blood and urine samples w...

journal_title：Calcified tissue international

authors： Thamsborg G,Skousgaard SG,Daugaard H,Schifter S,Kollerup G,Sørensen OH

更新日期：1993-10-01 00:00:00

abstract：:Pleiotrophin (PTN) was found to have potent effects on regulation of osteoblast recruitment, proliferation and differentiation. The present study examined the long-term effects of targeted PTN over-expression on bone development and repair in a transgenic mouse model. Femurs and tibiae from the PTN transgenic mice and...

journal_title：Calcified tissue international

authors： Li G,Bunn JR,Mushipe MT,He Q,Chen X

更新日期：2005-04-01 00:00:00

abstract：:The purpose of this study was to ascertain whether biochemical markers of bone turnover predict bone loss. The survey was carried out in Taiji, Wakayama Prefecture, Japan. From a list of inhabitants aged 40-79 years, 400 participants (50 men and 50 women in each of four age groups) were selected randomly. Bone mineral...

journal_title：Calcified tissue international

authors： Yoshimura N,Hashimoto T,Sakata K,Morioka S,Kasamatsu T,Cooper C

更新日期：1999-09-01 00:00:00

abstract：:Measurements of broadband ultrasonic attenuation (BUA) represent an established means of skeletal status assessment in osteoporosis. Today, the skeletal site that is the most widely used clinically is the calcaneus (heel bone). However, we hypothesized that fracture risk predictions could be improved if ultrasound mea...

journal_title：Calcified tissue international

authors： Padilla F,Akrout L,Kolta S,Latremouille C,Roux C,Laugier P

更新日期：2004-11-01 00:00:00

abstract：:Macroporous biphasic calcium phosphate (MBCP) blocks were implanted into rabbit trabecular bone and muscle, recovered 18 weeks later, and then observed and analyzed by transmission electron microscopy (TEM), electron diffraction, and electron microprobes. The results showed that (1) apatitic microcrystals appeared by ...

journal_title：Calcified tissue international

authors： Rohanizadeh R,Trécant-Viana M,Daculsi G

更新日期：1999-05-01 00:00:00

abstract：:The present report compares the effects of different membrane phospholipid (PL)-cholesterol compositions on the kinetics of liposome-mediated formation of calcium phosphates from metastable solutions (2.25 mM CaCl2; 1.5 mM KH2PO4) at 22 degrees C, pH 7.4 and 240 mOsm. In most experiments, the liposomes were composed o...

journal_title：Calcified tissue international

authors： Skrtic D,Eanes ED

更新日期：1992-03-01 00:00:00

abstract：:Parathyroid hormone (PTH), hPTH-(1-84), and its hPTH-(1-34), hPTH-(1-31)NH2, and hPTH-(1-30)NH2 fragments reduced the tail artery pressure in anesthetized female Sprague-Dawley rats by 42.4-67.1% within about 1 minute after injection into a femoral vein, but reduced the pressure by only 8.5-36.2% 2-19 minutes after su...

journal_title：Calcified tissue international

authors： Whitfield JF,Morley P,Ross V,Preston E,Soska M,Barbier JR,Isaacs RJ,Maclean S,Ohannessian-Barry L,Willick GE

更新日期：1997-03-01 00:00:00

abstract：:To assess whether vertebral fractures are associated with osteopenia in chronic alcoholic patients, a transversal study was carried out in 76 chronic alcoholic males and 62 age-matched healthy males. Lumbar bone mineral density (BMD) by dual photon absorptiometry and spinal chest X-ray films were done in all patients....

journal_title：Calcified tissue international

authors： Peris P,Guañabens N,Parés A,Pons F,del Rio L,Monegal A,Surís X,Caballería J,Rodés J,Muñoz-Gómez J

更新日期：1995-08-01 00:00:00

abstract：:Gnathodiaphyseal dysplasia (GDD; OMIM#166260) is a rare skeletal disorder which is mainly characterized by cemento-osseous lesions in mandibles, bone fragility, bowing and diaphyseal sclerosis of tubular bones. GDD is caused by point mutations in Anoctamin-5 (ANO5); however, the disease mechanisms remain unclear. Here...

journal_title：Calcified tissue international

authors： Wang X,Liu X,Dong R,Liang C,Reichenberger EJ,Hu Y

更新日期：2019-06-01 00:00:00

abstract：:Ribbon-like crystals, from developing enamel of human fetuses, were studied by high resolution electron microscopy. These crystals were classically described as the first organized mineral formed during amelogenesis. They were characterized by a mean width-to-thickness ratio (W.T-1) of 9.5, and 40% were bent. On latti...

journal_title：Calcified tissue international

authors： Cuisinier FJ,Steuer P,Senger B,Voegel JC,Frank RM

更新日期：1992-10-01 00:00:00

abstract：:Osteoporosis is commonly associated with estrogen deficiency. However, the mechanisms by which the lack of this hormone causes bone loss are poorly understood. The bone structure of the oral cavity seems to be affected by estrogen deficiency, since a delayed healing process after tooth extraction has been observed aft...

journal_title：Calcified tissue international

authors： Zecchin KG,Pereira MC,Coletta RD,Graner E,Jorge J

更新日期：2005-02-01 00:00:00

abstract：:We have previously noted that a relatively large load (150 N) is required to induce a strain on the cortex of rat vertebrae similar to that induced on weight-bearing bones by normal mechanical usage. It seems unlikely that the musculature of the tail normally imposes loads of this magnitude, and this suggests that the...

journal_title：Calcified tissue international

authors： Chow JW,Jagger CJ,Chambers TJ

更新日期：1996-08-01 00:00:00

abstract：:Even though indirect evidence indicates that PTH exerts an anabolic effect on dentinogenesis, the existence of PTH receptors and any second-messenger response in odontoblasts have not been demonstrated. The aim of this study was to investigate whether rat incisor odontoblasts express PTH receptors, and to identify whi...

journal_title：Calcified tissue international

authors： Lundgren T,Stenport V,Wetter A,Linde A

更新日期：1998-03-01 00:00:00

abstract：:Biochemical markers applicable to the ovariectomized rat model can provide important tools for studying the bone remodeling process in this animal model of postmenopausal osteoporosis. We describe the development and application of two biochemical markers, a C-telopeptide (of type-I collagen) enzyme-linked immunosorbe...

journal_title：Calcified tissue international

authors： Srivastava AK,Bhattacharyya S,Castillo G,Wergedal J,Mohan S,Baylink DJ

更新日期：2000-06-01 00:00:00

abstract：:Osteoblast differentiation is predominantly regulated by the WNT/β-catenin signaling (canonical WNT pathway), which, together with bone morphogenetic proteins, acts as the master regulator of osteogenesis. The recent characterization of the canonical WNT pathway in the regulation of bone modeling and remodeling provid...

journal_title：Calcified tissue international

authors： Rossini M,Gatti D,Adami S

更新日期：2013-08-01 00:00:00

abstract：:1,25 Dihydroxyvitamin D3 (1,25(OH)2D3) (2.0 micrograms) was given intramuscularly to 6 healthy adult males. Twenty-four circadian patterns of blood-ionized calcium (Ca2+), serum phosphate (Pi), and total calcium (CaT) were assessed pre- and posthormone administration. Correlations of mean mineral rhythms with normativ...

journal_title：Calcified tissue international

authors： Markowitz ME,Rosen JF,Mizruchi M

更新日期：1985-07-01 00:00:00

abstract：:The aim of this study was to evaluate bone resorption (BR) in rats by two methods: chronic 3H-tetracycline labeling (3HTC) and pyridinium crosslink excretion (PYDX), and compare the sensitivity of these markers in two age groups. Female Sprague-Dawley rats at 12-29 weeks of age ("mature", n = 12) and at 40-57 weeks of...

journal_title：Calcified tissue international

authors： Talbott SM,Chowdhury H,Shapses SA

更新日期：1999-04-01 00:00:00

abstract：:The small proteoglycan decorin had been localized previously at the d-band in the gap zone of collagen fibrils in nonmineralizing tissues. In bone matrix this zone is proteoglycan free and is at least in some species the place where mineralization along collagen fibrils starts. To study the metabolism of the small pro...

journal_title：Calcified tissue international

authors： Blumberg P,Brenner R,Budny S,Kresse H

更新日期：1997-06-01 00:00:00

abstract：:This study sought to develop a noninvasive, reliable, clinically relevant, and easy-to-implement mouse model that can be used for investigation of the pathophysiology of PTOA and for preclinical testing of new therapies of PTOA. Accordingly, we have established a closed intraarticular tibial plateau compression loadin...

journal_title：Calcified tissue international

authors： Stiffel V,Rundle CH,Sheng MH,Das S,Lau KW

更新日期：2020-02-01 00:00:00

abstract：:Toxicological studies have demonstrated that intermittent PTH1-34 treatment is associated with an increased incidence of osteosarcoma in Fischer 344 rats. Comet and micronucleus (MN) tests, standard methods to evaluate genotoxic potential of drugs, were used to detect DNA and chromosome breaks, respectively, after PTH...

journal_title：Calcified tissue international

authors： Alves de Oliveira EC,Szejnfeld VL,Pereira da Silva N,Coelho Andrade LE,Heldan de Moura Castro C

更新日期：2010-11-01 00:00:00

abstract：:Vitamin D supplementation is recommended for women with osteoporosis. In the FOCUS-D trial comparing the combination tablet alendronate plus vitamin D3 5,600 IU (ALN/D) with standard care (SC) prescribed by patients' personal physicians, ALN/D was more effective in improving serum 25(OH)D and bone turnover markers by ...

journal_title：Calcified tissue international

authors： Roux C,Binkley N,Boonen S,Kiel DP,Ralston SH,Reginster JY,Pong A,Rosenberg E,Santora A,FOCUS-D Investigators.

更新日期：2014-02-01 00:00:00