A Mouse Noninvasive Intraarticular Tibial Plateau Compression Loading-Induced Injury Model of Posttraumatic Osteoarthritis.

abstract：:Bone tissue is a source of growth factors; among them, insulinlike growth factor I (IGF-I) is probably an important local regulator of bone formation. This study has been carried out in order to assess the effects of natural menopause on plasma concentrations of IGF-I in the first 6 years after the cessation of gonada...

journal_title：Calcified tissue international

authors： Romagnoli E,Minisola S,Carnevale V,Scarda A,Rosso R,Scarnecchia L,Pacitti MT,Mazzuoli G

更新日期：1993-07-01 00:00:00

abstract：:Newly developed fuzzy logic-derived structural parameters were used to characterize trabecular bone architecture in high-resolution magnetic resonance imaging (HR-MRI) of human cadaver calcaneus specimens. These parameters were compared to standard histomorphological structural measures and analyzed concerning perform...

journal_title：Calcified tissue international

authors： Patel PV,Eckstein F,Carballido-Gamio J,Phan C,Matsuura M,Lochmüller EM,Majumdar S,Link TM

更新日期：2007-10-01 00:00:00

abstract：:The effect of the configuration of porous cylindrical hydroxyapatite (HA) scaffold and laminin preparation of the scaffold on bone formation was estimated. HA scaffolds with a hollow center of 2 or 4 mm in diameter and those without a hollow center were used. The scaffolds were immersed in laminin solution or in cultu...

journal_title：Calcified tissue international

authors： Yoshikawa M,Tsuji N,Shimomura Y,Hayashi H,Ohgushi H

更新日期：2008-08-01 00:00:00

abstract：:The objective of this study was to compare the bone mineral density (BMD) of men with Down syndrome (DS) to otherwise mentally retarded (MR) men and to investigate whether leg muscle strength of these patients is related to BMD. Two groups with MR (with and without DS) participated in the study, having met the followi...

journal_title：Calcified tissue international

authors： Angelopoulou N,Matziari C,Tsimaras V,Sakadamis A,Souftas V,Mandroukas K

更新日期：2000-03-01 00:00:00

abstract：:We describe a tall-statured 14-year-old boy who illustrated the full phenotypic and radiographic features of Stickler syndrome type I. A bone biopsy showed evidence of reduced bone mass and bone turnover, such as reduced BV/TV (-43%), TbTh (-29%), and OS/BS (-48%), Ob.S/BS (-27%), and Oc/BS (-47%) compared to "age-mat...

journal_title：Calcified tissue international

authors： Al Kaissi A,Roschger P,Nawrot-Wawrzyniak K,Krebs A,Grill F,Klaushofer K

更新日期：2010-02-01 00:00:00

abstract：:Unfixed, undecalcified sections from closed fractures of rat metatarsals have been studied by quantitative cytochemistry from the first week after fracture to late in the fracture-healing process. Alkaline phosphatase activity appeared to be related to calcification. Glucose 6-phosphate dehydrogenase activity was asso...

journal_title：Calcified tissue international

authors： Dunham J,Catterall A,Bitensky L,Chayen J

更新日期：1983-01-01 00:00:00

abstract：:An experimental fracture model was used to assess bone mineral density at the fracture site by peripheral computed tomography and to compare the model with biomechanical, histological, and radiographic methods for the quantification of the fracture repair process. Transverse osteotomies in the mid-diaphysis of 28 tibi...

journal_title：Calcified tissue international

authors： Augat P,Merk J,Genant HK,Claes L

更新日期：1997-02-01 00:00:00

abstract：:Vascular calcification (VC), which is associated with high cardiovascular morbidity and mortality in patients with chronic kidney disease, is promoted by the osteoblastic differentiation of vascular smooth muscle cells (VSMCs). The present study explored the functional roles and molecular mechanisms of the long noncod...

journal_title：Calcified tissue international

authors： Chang Z,Yan G,Zheng J,Liu Z

更新日期：2020-07-01 00:00:00

abstract：:The wedges of the mid-diaphyseal osteotomies carried out to correct the femoral and/or tibial native deformity in type III osteogenesis imperfecta (OI III) were used to study the remodeling patterns and lamellar organization at the level of the major deformity. Histology and scanning electron microscopy (SEM) morpholo...

journal_title：Calcified tissue international

authors： Pazzaglia UE,Congiu T,Brunelli PC,Magnano L,Benetti A

更新日期：2013-11-01 00:00:00

abstract：:Plasma osteocalcin (BGP), growth hormone (GH), and somatomedin C(SmC) were measured in 12 patients with acromegaly [7 clinically active (aA), 5 cured (cA)] and 9 control subjects (C). Basal plasma values for the three parameters were higher in aA than in C and in cA. No significant difference was found between cA and ...

journal_title：Calcified tissue international

authors： de la Piedra C,Larrañaga J,Castro N,Horcajada C,Rapado A,Herrera Pombo JL,Carbó E

更新日期：1988-07-01 00:00:00

abstract：:Twenty boys were followed during their puberty for about 2 years with examinations every third month. At each examination we determined serum concentrations of 25OHD3, 1,25(OH)2D3, 24,25(OH)2D3, 25.26(OH)2D3, alkaline phosphatase (AP) and testosterone together with bone mineral content (BMC) at the distal forearm. Hig...

journal_title：Calcified tissue international

authors： Krabbe S,Christiansen C,Hummer L

更新日期：1986-03-01 00:00:00

abstract：:The values of in vivo T1 relaxation time (T1) of phosphorus atoms of wrist bone have been measured by phosphorus-31 magnetic resonance spectroscopy (MRS) in 65 menopausal women separated into three groups: (1) age-matched women without any paraclinical or clinical osteoporosis; (2) patients with paraclinical osteoporo...

journal_title：Calcified tissue international

authors： Confort-Gouny S,Mattéi JP,Vion-Dury J,Roux H,Bisset JP,Cozzone PJ

更新日期：1995-06-01 00:00:00

abstract：:We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...

journal_title：Calcified tissue international

authors： Epstein S,Schlosberg M,Fallon M,Thomas S,Movsowitz C,Ismail F

更新日期：1990-09-01 00:00:00

abstract：:Amelogenins, the major protein components of the enamel extracellular matrix, are postulated to be involved in controlling the elongated and oriented growth of enamel carbonated apatite crystals. In order to clarify the functional role of amelogenin during the early stage of enamel biomineralization, octacalcium phosp...

journal_title：Calcified tissue international

authors： Iijima M,Moradian-Oldak J

更新日期：2004-06-01 00:00:00

abstract：:The tumor-suppressor p53 is a transcription factor that regulates a number of genes in the process of cell-cycle inhibition, apoptosis, and DNA damage. Recent studies have revealed a crucial role for p53 in bone remodeling. In our previous studies we have shown that p53 is an important regulator of osteoblast differen...

journal_title：Calcified tissue international

authors： Chen H,Hays E,Liboon J,Neely C,Kolman K,Chandar N

更新日期：2011-11-01 00:00:00

abstract：:Osteoporosis is characterized by low bone mass and a deterioration of bone architecture and likely is influenced by genetic factors. The ovariectomized (OVX) mouse is well suited for osteoporosis research, as shown to date by cross-sectional studies. Here, we investigate longitudinal changes by in vivo micro-computed ...

journal_title：Calcified tissue international

authors： Klinck J,Boyd SK

更新日期：2008-07-01 00:00:00

abstract：:There is considerable interest in determining whether hypergravity can be used as a countermeasure for microgravity-induced bone loss. This study was conducted on 20 immature male rats in order to investigate possible elastic adaptations of cortical bone in rapidly growing rats exposed to chronic hypergravity. Ten rat...

journal_title：Calcified tissue international

authors： Kohles SS,Bowers JR,Vailas AC,Vanderby R Jr

更新日期：1996-09-01 00:00:00

abstract：:Postmenopausal osteoporosis induced by estrogen deficiency causes inadequate new bone formation and affects millions of women worldwide. Melatonin can improve bone mineral density at the femoral neck in postmenopausal women with osteopenia. This study aimed to investigate the mechanism of melatonin in estrogen deficie...

journal_title：Calcified tissue international

authors： Xu L,Zhang L,Wang Z,Li C,Li S,Li L,Fan Q,Zheng L

更新日期：2018-10-01 00:00:00

abstract：:Conventional transmission electron microscopy requires an effective dehydration of the tissue specimens under investigation. This dehydration, for which ethanol most often is used, may influence the solubility of the slightly soluble calcium phosphates. To study the behavior of calcium phosphates in ethanol, stable ne...

journal_title：Calcified tissue international

authors： Larsen MJ,Thorsen A,Jensen SJ

更新日期：1985-03-01 00:00:00

abstract：:Pyrolyzed scales, fin spines, and bone from the ray-finned bony fish Polypterus (Actinopterygii) showed two mineral phases on X-ray diffraction: hydroxyapatite (HA), Ca5(PO4)3OH, and whitlockite, Ca3(PO4)2. The ratio of HA/whitlockite varied with the structure (scale, spine, bone) within each individual fish. The rela...

journal_title：Calcified tissue international

authors： Meinke DK,Skinner HC,Thomson KS

更新日期：1979-08-24 00:00:00

abstract：:Biochemical markers applicable to the ovariectomized rat model can provide important tools for studying the bone remodeling process in this animal model of postmenopausal osteoporosis. We describe the development and application of two biochemical markers, a C-telopeptide (of type-I collagen) enzyme-linked immunosorbe...

journal_title：Calcified tissue international

authors： Srivastava AK,Bhattacharyya S,Castillo G,Wergedal J,Mohan S,Baylink DJ

更新日期：2000-06-01 00:00:00

abstract：:We carried out a clinical trial of 1 alpha-hydroxycholecalciferol [1 alpha(OH)D3] at a dose of 1.0 microgram a day on 7 patients with psoriasis vulgaris. These patients had been treated by topical applications of corticosteroids before this study without improvement, and during the clinical trial, treatment of topical...

journal_title：Calcified tissue international

authors： Takamoto S,Onishi T,Morimoto S,Imanaka S,Yukawa S,Kozuka T,Kitano Y,Seino Y,Kumahara Y

更新日期：1986-12-01 00:00:00

abstract：:To clarify the mechanisms underlying shockwave-induced osteogenesis, we applied shockwave to rat femoral shafts from the ventral side. We assessed bone mineral content (BMC) and bone mineral density (BMD), and analyzed the spatial and temporal gene expression for pro-alpha1 (I) collagen (COL1A1), pro-alpha1 (II) colla...

journal_title：Calcified tissue international

authors： Takahashi K,Yamazaki M,Saisu T,Nakajima A,Shimizu S,Mitsuhashi S,Moriya H

更新日期：2004-02-01 00:00:00

abstract：:The purpose of this study is to evaluate degenerative factors in a postmenopausal patient group and differentiate the influence on bone mineral density (BMD) measurements by dual-energy X-ray absorptiometry (DXA). The patients and methods included an investigation of 144 postmenopausal women (mean 63.3 years) with PA-...

journal_title：Calcified tissue international

authors： Rand T,Seidl G,Kainberger F,Resch A,Hittmair K,Schneider B,Glüer CC,Imhof H

更新日期：1997-05-01 00:00:00

abstract：:Because of the variability of collagen crosslinks, their use as markers for bone resorption is often criticized. We hypothesized that the variability could be reduced by collecting urine for 24 hours (or longer) instead of using single voids, and by not normalizing to creatinine. Urine samples were collected from 22 h...

journal_title：Calcified tissue international

authors： Smith SM,Dillon EL,DeKerlegand DE,Davis-Street JE

更新日期：2004-04-01 00:00:00

abstract：:Previous observational studies have identified various risk factors associated with the development of osteoporosis, including sex hormone-binding globulin (SHBG). The aim of this study was to determine the potential causal effects of circulating SHBG concentrations on bone mineral density (BMD). Two-sample Mendelian ...

journal_title：Calcified tissue international

authors： Qu Z,Jiang J,Yang F,Huang J,Zhao J,Yan S

更新日期：2020-10-17 00:00:00

abstract：:The purpose of this study is to estimate the efficacy of eldecalcitol (1α, 25-Dihydroxy-2β- (3-hydroxypropyloxy) vitamin D3; ELD) on bone metabolism after long-term administration. Six-month-old Wistar-Imamichi rats were ovariectomized (OVX) and administered ELD orally at doses of 7.5, 15, or 30 ng/kg daily. Bone mine...

journal_title：Calcified tissue international

authors： Takeda S,Smith SY,Tamura T,Saito H,Takahashi F,Samadfam R,Haile S,Doyle N,Endo K

更新日期：2015-01-01 00:00:00

abstract：:Methotrexate (MTX) is one of the most commonly prescribed drugs for autoimmune rheumatic diseases. As there is no consensus on its negative effects on bone, the purpose of this investigation was to determine the clinical spectrum of patients with stress fractures due to long-term MTX treatment (i.e., MTX osteopathy). ...

journal_title：Calcified tissue international

authors： Rolvien T,Jandl NM,Stürznickel J,Beil FT,Kötter I,Oheim R,Lohse AW,Barvencik F,Amling M

更新日期：2021-02-01 00:00:00

abstract：:To study the risk of fractures associated with anxiolytics, sedatives, and hypnotics, we conducted a case-control study. Cases were all subjects with any fracture during the year 2000 (n = 124,655). For each case, three controls (n = 373,962) matched on age and gender were randomly drawn from the background population...

journal_title：Calcified tissue international

authors： Vestergaard P,Rejnmark L,Mosekilde L

更新日期：2008-01-01 00:00:00

abstract：:We treated four hypercalcemic cancer patients by nasal hCT, 3 x 2 mg daily, which has been reported to be active in Paget's disease at lower doses. Only one patient became normocalcemic and mean (+/- SEM) calcium levels fell from 11.6 +/- 0.2 mg/dl before therapy to 10.7 +/- 0.6 mg/dl 2-3 days after starting hCT. The ...

journal_title：Calcified tissue international

authors： Dumon JC,Magritte A,Body JJ

更新日期：1992-07-01 00:00:00