Correlation among plasma osteocalcin, growth hormone, and somatomedin C in acromegaly.

abstract：:The dentin-enamel junction (DEJ) plays an important role in preventing crack propagation from enamel into dentin. This function stems from its complex structure and materials properties that are different from either dentin or enamel. The molecular structural differences in both mineral and organic matrix across the D...

journal_title：Calcified tissue international

authors： Xu C,Yao X,Walker MP,Wang Y

更新日期：2009-03-01 00:00:00

abstract：:Cortical bone can be modeled as a complex hierarchical composite interrelating both structure and material properties on four levels of structural organization: molecular, ultrastructural, microscopic, and macroscopic. In young animals, the microstructural systems are long parallel lamellar units, plexiform bone, whic...

journal_title：Calcified tissue international

authors： Katz JL,Yoon HS,Lipson S,Maharidge R,Meunier A,Christel P

更新日期：1984-01-01 00:00:00

abstract：:The effect of parathormone (PTH), lipopolysaccharide (LPS), or interleukin-1 (IL-1) on calcium release and collagen degradation in bone was examined in vitro using labeled neonatal calvaria of normal mice and also of osteopetrotic microphthalmic (mi/mi) mice that have defective osteoclasts. All three agents stimulated...

journal_title：Calcified tissue international

authors： Jilka RL,Hamilton JW

更新日期：1985-05-01 00:00:00

abstract：:In this study, we demonstrated that type I collagen matrix induced the expression of osteoblastic phenotypes of bone marrow cells, and that antibone sialoprotein (BSP) monoclonal antibody suppressed the expression of these phenotypes. On the other hand, BSP accelerated the expression of osteoblastic phenotypes of bone...

journal_title：Calcified tissue international

authors： Mizuno M,Imai T,Fujisawa R,Tani H,Kuboki Y

更新日期：2000-05-01 00:00:00

abstract：:Differences in trabecular and cortical bone loss have been demonstrated clinically, but differences in bone loss at different skeletal sites remain unclear. We examined regional variations in bone loss histomorphometrically in two strains of mice in which osteopenia progresses spontaneously: tiptoe-walking Yoshimura (...

journal_title：Calcified tissue international

authors： Kobayashi Y,Goto S,Tanno T,Yamazaki M,Moriya H

更新日期：1998-05-01 00:00:00

abstract：:We hypothesized that reactive oxygen species play an important role in avascular/ischemic osteonecrosis. When isolated chick osteocytes were cultured with hydrogen peroxide, annexin V binding, which is the earliest marker of apoptosis, increased in a dose-dependent fashion. Hydrogen peroxide also induced the activatio...

journal_title：Calcified tissue international

authors： Kikuyama A,Fukuda K,Mori S,Okada M,Yamaguchi H,Hamanishi C

更新日期：2002-09-01 00:00:00

abstract：:Osteoporosis is a bone disease leading to an increased fracture risk. It is considered a complex multifactorial genetic disorder with interaction of environmental and genetic factors. As a candidate gene for osteoporosis, we studied vitamin D binding protein (DBP, or group-specific component, Gc), which binds to and t...

journal_title：Calcified tissue international

authors： Fang Y,van Meurs JB,Arp P,van Leeuwen JP,Hofman A,Pols HA,Uitterlinden AG

更新日期：2009-08-01 00:00:00

abstract：:The purpose of this study was to determine whether human parathyroid hormone (h-PTH) enhances trabecular bone mass and connectivities that were reduced by streptozotocin (STZ)-induced diabetes in rats. Seven-month-old female Wistar rats were injected with STZ or its vehicle intraperitoneally. All vehicle-injected norm...

journal_title：Calcified tissue international

authors： Tsuchida T,Sato K,Miyakoshi N,Abe T,Kudo T,Tamura Y,Kasukawa Y,Suzuki K

更新日期：2000-03-01 00:00:00

abstract：:Osteoarthritis (OA), the most prevalent chronic joint disease, increases in prevalence with age, and affects majority of individuals over the age of 65 and is a leading musculoskeletal cause of impaired mobility in the elderly. Because the precise molecular mechanisms which are involved in the degradation of cartilage...

journal_title：Calcified tissue international

authors： Xia B,Di Chen,Zhang J,Hu S,Jin H,Tong P

更新日期：2014-12-01 00:00:00

abstract：:Prostaglandin E2 and leukotriene B4 are metabolites of arachidonic acid with well-characterized effects on osteoblastic cells. Prostaglandin E2 has been shown to be a potent bone-resorbing agent and to stimulate as well as inhibit osteoblastic cell proliferation. Leukotriene B4 has also been demonstrated to stimulate ...

journal_title：Calcified tissue international

authors： Ren W,Kinniburgh AJ,Dziak R

更新日期：1992-04-01 00:00:00

abstract：:Forty 5-week-old rats were randomly divided into 1 control group given a normal diet and water low in fluoride (0.026 mM/1) and experimental group receiving the same basic diet and a fluoride supplement of 2.6 mMol/l in the drinking water. After 30 weeks, half of the fluoride-supplemented and half of the nonsupplement...

journal_title：Calcified tissue international

authors： Rosenquist JB,Lorentzon PR,Boquist LL

更新日期：1983-07-01 00:00:00

abstract：:The aim of this work was a preliminary assessment of the feasibility of using in vivo measurements of mechanical properties of bones to detect mineral loss and further to relate them to the tendency of the bone to fracture in the case of loss of minerals, such as in osteoporosis. Previous studies of bone strength in v...

journal_title：Calcified tissue international

authors： Dimarogonas AD,Abbasi-Jahromi SH,Avioli LV

更新日期：1993-03-01 00:00:00

abstract：:Regular physical activity (PA) is associated with reduced risk of the development and progression of musculoskeletal, metabolic and vascular disease. However, PA declines with age and this can contribute to multiple adverse outcomes. The aims of this study were to describe the relationship between accelerometer-determ...

journal_title：Calcified tissue international

authors： Westbury LD,Dodds RM,Syddall HE,Baczynska AM,Shaw SC,Dennison EM,Roberts HC,Sayer AA,Cooper C,Patel HP

更新日期：2018-09-01 00:00:00

abstract：:Low-grade inflammation negatively affects bone. Resveratrol is a natural compound proven to possess both anti-inflammatory and bone protective properties. However, it is uncertain if the bone effects are mediated though anti-inflammatory effects. Firstly, we investigated if resveratrol affects proliferation and differ...

journal_title：Calcified tissue international

authors： Ornstrup MJ,Harsløf T,Sørensen L,Stenkjær L,Langdahl BL,Pedersen SB

更新日期：2016-08-01 00:00:00

abstract：:We describe a tall-statured 14-year-old boy who illustrated the full phenotypic and radiographic features of Stickler syndrome type I. A bone biopsy showed evidence of reduced bone mass and bone turnover, such as reduced BV/TV (-43%), TbTh (-29%), and OS/BS (-48%), Ob.S/BS (-27%), and Oc/BS (-47%) compared to "age-mat...

journal_title：Calcified tissue international

authors： Al Kaissi A,Roschger P,Nawrot-Wawrzyniak K,Krebs A,Grill F,Klaushofer K

更新日期：2010-02-01 00:00:00

abstract：:Even though indirect evidence indicates that PTH exerts an anabolic effect on dentinogenesis, the existence of PTH receptors and any second-messenger response in odontoblasts have not been demonstrated. The aim of this study was to investigate whether rat incisor odontoblasts express PTH receptors, and to identify whi...

journal_title：Calcified tissue international

authors： Lundgren T,Stenport V,Wetter A,Linde A

更新日期：1998-03-01 00:00:00

abstract：:Serum immunoreactive osteocalcin (irOC) consists of two fractions that differ from each other by their affinity for hydroxyapatite. The high and low affinity fractions are referred to as irOCbound and irOCfree, respectively. To evaluate whether these fractions are determinants for different characteristics of bone or ...

journal_title：Calcified tissue international

authors： Knapen MH,Nieuwenhuijzen Kruseman AC,Wouters RS,Vermeer C

更新日期：1998-11-01 00:00:00

abstract：:The aim of this work was to explore the reduction of fluoride concentrations in the skeleton after stopping experimental fluoride administration. Fluoride was administered to the rats at varying doses (0, 50, 100 ppm in drinking water) and for different lengths of time (4, 13, 25 weeks). A series of fluoride concentra...

journal_title：Calcified tissue international

authors： Li J,Nakagaki H,Kato K,Tsuboi S,Kato S,Morita I,Ohno N,Kameyama Y,Chen R,Robinson C

更新日期：1995-04-01 00:00:00

abstract：:We studied the effect of raloxifene (RAL) on arthritis and bone mineral density (BMD) in rats with collagen-induced arthritis (CIA). Seven-month-old female Sprague-Dawley rats were divided into five groups: rats without CIA (CNT), CIA rats that underwent ovariectomy (OVX) and were treated with RAL (CIA + OVX + RAL), C...

journal_title：Calcified tissue international

authors： Hayashi I,Hagino H,Okano T,Enokida M,Teshima R

更新日期：2011-02-01 00:00:00

abstract：:Conventional glucocorticoids exert a negative influence on calcium balance, and long-term treatment with these agents leads to osteopenia. Deflazacort is an oxazoline derivative of prednisolone with documented calcium-sparing properties when compared to prednisone on a weight basis. The purpose of the present study wa...

journal_title：Calcified tissue international

authors： Lund B,Egsmose C,Jørgensen S,Krogsgaard MR

更新日期：1987-12-01 00:00:00

abstract：:This study examines the efficacy of using radiolabeled thymidine as a measure of bone cell DNA synthesis. The effect of a bone-active peptide on cell proliferation is assessed under different labeling conditions and it is shown that the apparent stimulation in DNA synthesis is due to an increase in participating cells...

journal_title：Calcified tissue international

authors： Puzas JE,Brand JS

更新日期：1986-08-01 00:00:00

abstract：:Thyroparathyroidectomized rats fed a diet containing 1.2% calcium, 0.55% phosphorus maintain normal serum levels of these ions. Treatment of such rats with parathyroid extract (PTE; 20 U/100 g twice daily; 10 days) has no statistically significant effect on rates of bone formation, matrix apposition, or osteoid matura...

journal_title：Calcified tissue international

authors： Rader JI,Howard GA,Feist E,Turner RT,Baylink DJ

更新日期：1979-11-01 00:00:00

abstract：:Bone loss occurs as early as the third decade and its cumulative effect throughout adulthood may impact risk for osteoporosis in later life, however, the genes and environmental factors influencing early bone loss are largely unknown. We investigated the role of genes in the change in bone mineral density (BMD) in par...

journal_title：Calcified tissue international

authors： Shaffer JR,Kammerer CM,Bruder JM,Cole SA,Dyer TD,Almasy L,Maccluer JW,Blangero J,Bauer RL,Mitchell BD

更新日期：2009-02-01 00:00:00

abstract：:To clarify the mechanisms underlying shockwave-induced osteogenesis, we applied shockwave to rat femoral shafts from the ventral side. We assessed bone mineral content (BMC) and bone mineral density (BMD), and analyzed the spatial and temporal gene expression for pro-alpha1 (I) collagen (COL1A1), pro-alpha1 (II) colla...

journal_title：Calcified tissue international

authors： Takahashi K,Yamazaki M,Saisu T,Nakajima A,Shimizu S,Mitsuhashi S,Moriya H

更新日期：2004-02-01 00:00:00

abstract：:Human osteoblasts were obtained by migration and proliferation of cells from embryonic membranous bone on glass fragments. Light and electron microscopy analyses revealed a typical osteoblast-like appearance with high protein synthesis activity. The cells showed high alkaline phosphatase activity that was associated w...

journal_title：Calcified tissue international

authors： Oliva A,Marrone G,Della Ragione F,Riccio V,Palumbo R,Rossano F,Zappia V

更新日期：1992-11-01 00:00:00

abstract：:We separated osteoclasts from bone and observed the effect of several known and potential mediators of the control of bone resorption on their cytoplasmic motility. We already found that calcitonin (CT), a hormone that inhibits bone resorption, regularly causes complete inhibition of cytoplasmic motility, specific for...

journal_title：Calcified tissue international

authors： Chambers TJ,Dunn CJ

更新日期：1983-07-01 00:00:00

abstract：:The effect of magnesium (Mg) supplementation on bone metabolism has been studied in the normal young mouse. Weanling male mice were given Mg-supplemented drinking water (5 mM or 32 mM Mg) for 4 weeks. Mineral and skeletal changes were assessed by biochemical methods and by histomorphometric analysis of endosteal bone ...

journal_title：Calcified tissue international

authors： Marie PJ,Travers R,Delvin EE

更新日期：1983-09-01 00:00:00

abstract：:Extracellular ATP, and to a lesser extent adenosine, an ATP metabolite, stimulated cell proliferation in osteoblast-like cells (MC3T3-E1). ATP increased cytosolic Ca2+ due to Ca2+ mobilization from intracellular storage in the same concentration range of the nucleotide as that effective for DNA synthesis, suggesting t...

journal_title：Calcified tissue international

authors： Shimegi S

更新日期：1996-02-01 00:00:00

abstract：:The purpose of this study is to evaluate degenerative factors in a postmenopausal patient group and differentiate the influence on bone mineral density (BMD) measurements by dual-energy X-ray absorptiometry (DXA). The patients and methods included an investigation of 144 postmenopausal women (mean 63.3 years) with PA-...

journal_title：Calcified tissue international

authors： Rand T,Seidl G,Kainberger F,Resch A,Hittmair K,Schneider B,Glüer CC,Imhof H

更新日期：1997-05-01 00:00:00

abstract：:Risk factors for increased mortality in hip fracture patients include older age, male sex, fracture type, bone mineral density, and pre-existing co-morbidities. The role of biochemical and other anthropometric parameters on hip fracture mortality remains unclear. The aim of this study was to identify the risk factors ...

journal_title：Calcified tissue international

authors： Gulin T,Kruljac I,Kirigin L,Merc M,Pavić M,Trcin MT,Bokulić A,Megla ŽB,Kaštelan D

更新日期：2016-01-01 00:00:00