Abstract:
:The developing mandibular condylar growth center consists of a number of histologically distinct cell types. There is an increase in cell volume that takes place from the condylar surface layer through the center of ossification, resulting in a disorganized, irregular cellular pattern. Consequently, the isolation and separation of the different cells from this tissue is difficult using standard methodologies. Countercurrent centrifugal elutriation, whereby cells are separated on the basis of size, was applied to bovine mandibular condylar growth center cells. The cell volume, alkaline phosphatase content, proteoglycan synthesis, and type X collagen synthesis all showed a positive correlation with increasing cell size. The largest cells had characteristics that are consistent with hypertrophic chondrocytes; the smallest cells, on the other hand, had many fibroblastic characteristics.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Landesberg R,Proctor RL,Rosier RN,Puzas JEdoi
10.1007/BF00298747subject
Has Abstractpub_date
1995-01-01 00:00:00pages
71-7issue
1eissn
0171-967Xissn
1432-0827journal_volume
56pub_type
杂志文章abstract::The present study was undertaken to determine the fluoride distribution profile in the rat femur. Male Wistar rats were divided into four groups and given water containing 0, 25, 50, and 100 ppm of fluoride, respectively, for 10 weeks. The fluoride distribution from the periosteum to the endosteum was determined in ea...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555045
更新日期:1990-03-01 00:00:00
abstract::Dual photon absorptiometry (DPA) is currently the most widely used method for noninvasive bone mineral density (BMD) measurement of the axial skeleton. Dual energy X-ray absorptiometry (DEXA) is a recently developed technique that uses an X-ray tube as a photon source; it has demonstrated several significant advantage...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02556250
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journal_title:Calcified tissue international
pub_type: 杂志文章
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-012-9617-2
更新日期:2012-08-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010045
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abstract::1,25(OH)2D3 was found to regulate its own receptor levels via an increase in corresponding mRNA levels in human osteoblast-like osteosarcoma cells (MG-63). In addition, exposure of the cells for 24h to dexamethasone, estradiol, retinoic acid, or triiodothyronine resulted in a dose-dependent accumulation of hVDR mRNA. ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555101
更新日期:1991-01-01 00:00:00
abstract::Mice deficient in the chloride channel ClC-7, which is likely involved in acidification of the resorption lacuna, display severe osteopetrosis. To fully characterize the osteopetrotic phenotype, the phenotypes of osteoclasts and osteoblasts were evaluated. ClC-7(-/-) mice and their corresponding wild-type littermates ...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-008-9185-7
更新日期:2008-12-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-003-0110-9
更新日期:2004-03-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-010-9393-9
更新日期:2010-09-01 00:00:00
abstract::Bone turnover markers (BTMs) are widely used for the management of osteoporosis, and the premenopausal reference range is the target value for the treatment of postmenopausal osteoporosis with antiresorbing agents. Three serum BTMs (serum C-telopeptide of type I collagen [CTX], osteocalcin [OC], and N-terminal propept...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-008-9126-5
更新日期:2008-05-01 00:00:00
abstract::Changes in the acidity of osteoclasts were evaluated by direct measurement of the fluorescent intensity of osteoclasts exposed to acridine orange, a fluorescent weak base which becomes concentrated in acid-containing subcellular compartments. Parathyroid hormone (PTH) produced dose-dependent increases in fluorescent i...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02554924
更新日期:1985-12-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章,评审
doi:10.1007/s00223-020-00787-z
更新日期:2021-01-16 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900533
更新日期:1998-10-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-002-0036-7
更新日期:2003-11-01 00:00:00
abstract::Although radiogenic free radicals are widely used as molecular probes in biological calcified tissues, their nature and their location remain controversial. In the present study we have synthesized and irradiated apatites in which 13CO3(2-) ions substitute hydroxyl or phosphate ions in hydroxyapatite. The 13C-coupling...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02555150
更新日期:1988-08-01 00:00:00
abstract::KH1060 is a new 20-epi-vitamin D3 analog, which has exerted a considerable immunosuppressive potency in vitro. We have tested in vivo the effect of KH1060 on the suppression of renal allograft rejection in the rat. Allogenic kidney transplantation from DA donor rats to Lewis recipient rats treated intraperitoneally wi...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00296066
更新日期:1994-02-01 00:00:00
abstract::Osteocalcin, the gamma-carboxyglutamic acid-containing protein, which is the most abundant noncollagenous protein of bone and dentin, is considered to play roles in bone formation and remodeling. It is unclear how the gamma-carboxyglutamic acid side-chains in osteocalcin coordinate to Ca2+, since the X-ray structure o...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002230010042
更新日期:2001-12-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF00299317
更新日期:1994-11-01 00:00:00
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,随机对照试验
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02553700
更新日期:1985-07-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02554998
更新日期:1990-04-01 00:00:00
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journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-003-0149-7
更新日期:2004-04-01 00:00:00
abstract::The interaction between estrogens and androgens, with their protective effects in bone, and parathyroid hormone (PTH), a calcitropic peptide hormone, is complex but may be better understood with murine models. The purpose of this study was to characterize skeletal phenotypes of mice deficient in estrogen receptor alph...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-004-0119-8
更新日期:2004-07-01 00:00:00
abstract::Calcaneus bone mineral density (BMD) of 738 Japanese women (605 healthy and 133 with osteoporosis) was measured using single X-ray absorptiometry (SXA). A reference range of calcaneus BMD values for healthy Japanese women was established and the usefulness of this method for screening and diagnosis of osteoporosis was...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s002239900665
更新日期:1999-08-01 00:00:00
abstract::Hyperthyroidism and thyroid hormone substitutive therapy with serum iT3 in the normal range of values are known to lead to increased bone remodeling and loss of bone mass. We looked for a relationship between serum iT3 and bone metabolic or bone mass parameters in 402 euthyroid women aged 44-60. In a group of 93 preme...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02565128
更新日期:1991-08-01 00:00:00
abstract::The CYP3A7 enzyme metabolizes some steroid hormones, including dehydroepiandrosterone sulfate (DHEAS). The age-related decline of serum DHEAS levels is believed to contribute to osteoporosis. Previously, the CYP3A7*1C polymorphism has been shown to cause a persistent high CYP3A7 enzyme activity, resulting in lower lev...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-006-0227-8
更新日期:2007-03-01 00:00:00
abstract::We separated osteoclasts from bone and observed the effect of several known and potential mediators of the control of bone resorption on their cytoplasmic motility. We already found that calcitonin (CT), a hormone that inhibits bone resorption, regularly causes complete inhibition of cytoplasmic motility, specific for...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/BF02405095
更新日期:1983-07-01 00:00:00
abstract::The effect of ascorbic acid deficiency on bone metabolism was evaluated using the ascorbate-requiring Osteogenic Disorder Shionogi (ODS) rat model. Ascorbic acid (Asc)-deficient rats gained body weight in a manner similar to Asc-supplemented rats (control) during 3 weeks, but began to lose weight during the 4th week o...
journal_title:Calcified tissue international
pub_type: 杂志文章
doi:10.1007/s00223-002-2040-3
更新日期:2003-08-01 00:00:00