Abstract：
:Prosected vertebrae and phalanges from 32 cadavera were examined using noninvasive methods commonly used for assessment of osteoporosis. Bone measures were then compared with a strength variable obtained by mechanically crushing or breaking the bones. All of the phalangeal density assessment techniques were found to be significantly correlated with the bone strength. The highest correlations were between bone mineral content and strength. In vertebral samples (cubes with 2 cm sides), bone mineral content corrected for bone width (BMC/BW) was significantly correlated with the force at the first deviation from linearity. Correlations between the computed tomography number and bone strength were negligible. Bone strength of the vertebrae was significantly correlated to that of the fingers. Photon absorptometric (SPA) measurements of the vertebrae correlated significantly with corresponding measures of the phalanges. BMC/BW appeared as the first or second variable selected as a predictor of bone strength in the multiple regression analysis. Throughout this entire study, BMC or BMC/BW were the only variables that were consistently related to the strength variables.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Oyster N,Smith FWdoi
10.1007/BF02555150subject
Has Abstractpub_date
1988-08-01 00:00:00pages
77-82issue
2eissn
0171-967Xissn
1432-0827journal_volume
43pub_type
杂志文章abstract：:Vitamin D has long been known to be important for bone health, but there is currently no consensus on the amount of vitamin D needed or how it varies with age, race/ethnicity, body size, absorption efficiency, season, and other factors. This review describes the effects of vitamin D on calcium absorption, parathyroid ...
journal_title：Calcified tissue international
pub_type： 杂志文章,评审
doi：10.1007/s00223-012-9606-5
更新日期：2013-02-01 00:00:00
abstract：:Diets with a high saturated fat content can produce deleterious effects on the absorption of dietary calcium and consequently an adverse effect on bone mineralization in growing animals. Hence dietary fat may have long-term consequences for skeletal health and skeletal pathologies such as osteoporosis. Whether a diet ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900492
更新日期：1998-07-01 00:00:00
abstract：:The bone mineral density (BMD) of the spine was measured in the posteroanterior (PA) and lateral projections as well as the total body BMD in 447 black and white women. The lateral projection is comprised predominantly of cancellous bone whereas the total body BMD is predominantly cortical bone, and the PA spine is in...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900653
更新日期：1999-07-01 00:00:00
abstract：:Parathyroid hormone (PTH), hPTH-(1-84), and its hPTH-(1-34), hPTH-(1-31)NH2, and hPTH-(1-30)NH2 fragments reduced the tail artery pressure in anesthetized female Sprague-Dawley rats by 42.4-67.1% within about 1 minute after injection into a femoral vein, but reduced the pressure by only 8.5-36.2% 2-19 minutes after su...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900233
更新日期：1997-03-01 00:00:00
abstract：:Relapse after orthodontic tooth movement is a significant problem in orthodontics. The purpose of this study was to examine the efficacy of the osteoclast inhibitor osteoprotegerin-Fc (OPG-Fc) for inhibiting postorthodontic relapse. Rat maxillary molars were moved mesially and allowed to relapse for 24 days. Low-dose ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-012-9579-4
更新日期：2012-04-01 00:00:00
abstract：:The bone anabolic effect of parathyroid hormone (PTH) therapy is blunted when used in patients who were previously on bisphosphonate treatment. Osteocytes may play a role in the bisphosphonate silencing effect on PTH therapy since bisphosphonates have been shown to reach the lacunocanalicular system. In vivo osteocyte...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-013-9720-z
更新日期：2013-06-01 00:00:00
abstract：:Vitamin D3 deficient (D-) mice show a depressed inflammatory response and both inflammatory peritoneal macrophages and bone marrow polymorphonuclear leukocytes of D- mice exhibit a decreased spontaneous migration under agarose. The impaired phagocytic response of peritoneal macrophages from D- mice can be corrected by...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02409507
更新日期：1981-01-01 00:00:00
abstract：:Ribbon-like crystals, from developing enamel of human fetuses, were studied by high resolution electron microscopy. These crystals were classically described as the first organized mineral formed during amelogenesis. They were characterized by a mean width-to-thickness ratio (W.T-1) of 9.5, and 40% were bent. On latti...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF00334485
更新日期：1992-10-01 00:00:00
abstract：:Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223001093
更新日期：2000-07-01 00:00:00
abstract：:This study aims to test the hypothesis that noninvasive bone mass measurements can be used to predict bone strength in a piglet model. Dual energy X-ray absorptiometry measurements of bone mineral content (BMC), bone mineral density (BMD), and bone area (BA) were obtained from four sets of bones (left and right humeri...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002230010006
更新日期：2001-04-01 00:00:00
abstract：:Proteoglycans are recognized to inhibit calcium pyrophosphate dihydrate (CPPD) crystal formation but the mechanisms are not known. To study the role of carboxylate (-CO2-) ligands, the possible inhibitor effects of sodium acetate, sodium D-glucuronate, disodium malate, and trisodium citrate were studied using solution...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02555838
更新日期：1988-01-01 00:00:00
abstract：:The development of prophylaxes and treatments of bone diseases that can effectively increase the strength of bone as a structure necessitates a better understanding of the time course by which chemical properties define the stiffness of the material during primary and secondary mineralization. It was hypothesized that...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-005-0148-y
更新日期：2005-12-01 00:00:00
abstract：:Normative bone mineral density (BMD) and bone mineral content (BMC) values for the total body (TB), proximal femur (PF), and antero-posterior lumbar spine (LS) were obtained from a large cross-sectional sample of children and adolescents who were 8-17 years of age. There were 977 scans for the TB, 892 for the PF, and ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900138
更新日期：1996-11-01 00:00:00
abstract：:ELISAs for measuring the urinary excretion of collagen crosslinks and related peptides appear to show marked differences in sensitivity to anti-resorptive therapy. This presumably reflects variations in specificity of the anylate being detected in these assays, and the way in which they respond to treatment. To clarif...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900148
更新日期：1996-11-01 00:00:00
abstract：:In 11 postmenopausal women with histologically proven osteoporosis and normal lactose tolerance, a direct correlation between calcium absorption and intestinal lactase activity was observed. The results suggest that varying degrees of relative deficiencies in intestinal lactase might contribute to the graded decrease ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02557688
更新日期：1985-01-01 00:00:00
abstract：:The effects of 5, 10, and 20% dietary xylitol supplementations on the resorption of bone were studied. The resorption was measured by the urinary excretion of [3H] radioactivity from [3H]tetracycline-prelabeled rats. The 10 and 20% oral xylitol administrations caused a significant decrease in the excretion of [3H] as ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF00298616
更新日期：1995-03-01 00:00:00
abstract：:Total fat mass plays a significant role in determining bone mass, but the specific role of central adiposity independent of total fat mass has not been widely studied. Prepubertal (Tanner 1) children (n = 181; 65 boys, 116 girls, 7.8 +/- 1.5 years), including 99 Caucasians and 82 African Americans from Birmingham, Ala...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-006-0116-1
更新日期：2006-12-01 00:00:00
abstract：:Pregnancy and lactation-associated osteoporosis (PAO) is a rare condition with little known pathophysiology. Most cases are diagnosed in the third trimester of pregnancy or in the first weeks postpartum, particularly in first pregnancies. Vertebral fractures are most commonly observed and characterised by prolonged se...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-015-0028-z
更新日期：2015-10-01 00:00:00
abstract：:Proton pump inhibitors are taken by millions of patients for prevention and treatment of gastroesophageal diseases. Case-control studies have suggested that use of omeprazole is associated with an increased risk of hip fractures. The aim of this prospective study was to assess the risk of vertebral fractures in postme...
journal_title：Calcified tissue international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00223-008-9188-4
更新日期：2009-01-01 00:00:00
abstract：:Enhanced osteoclast formation and function is a fundamental cause of alterations to bone structure and plays an important role in several diseases impairing bone quality. Recent work revealed that TRP calcium channels 3 and 6 might play a special role in this context. By analyzing the bone phenotype of TRPC6-deficient...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-020-00673-8
更新日期：2020-06-01 00:00:00
abstract：:A number of osteoporotic patients under bisphosphonate treatment present persistent fragility fractures and bone loss despite good compliance. The objective of this 18-month prospective study was to investigate the effect of teriparatide [rhPTH(1-34)] in 25 female osteoporotics who were inadequate responders to oral b...
journal_title：Calcified tissue international
pub_type： 临床试验,杂志文章
doi：10.1007/s00223-011-9500-6
更新日期：2011-08-01 00:00:00
abstract：:The orientation of nanoscale mineral platelets was quantitatively evaluated in relation to the shape of lacunae associated with partially embedded osteocytes (osteoblastic-osteocytes) on the surface of deproteinised trabecular bone of adult sheep. By scanning electron microscopy and image analysis, the mean orientatio...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-015-0072-8
更新日期：2016-02-01 00:00:00
abstract：:Regular tennis play is associated with impressive asymmetries in bone strength in favor of the racquet arm, particularly in the humerus. However, the relative effects of service and ground strokes are not known. Serendipitously, we encountered a 46-year-old regular tennis player who has played service and ground strok...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-015-9995-3
更新日期：2015-08-01 00:00:00
abstract：:It has been well established that bone morphogenetic protein-2 (BMP-2) can induce bone formation bothin vivo andin vitro, although high concentrations (up to milligrams) of BMP-2 have been required to achieve this effectin vivo. Further, clinical applications are usually limited to a single dose at the time of implant...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02678146
更新日期：2001-02-01 00:00:00
abstract：:This study aimed to evaluate the association between objectively measured habitual physical activity and calcaneal and forearm bone mineral density (BMD, g/cm(2)), one mechanically more loaded and one less loaded skeletal region, in children aged 6-8 years. BMD was measured in 297 boys and 265 girls by peripheral dual...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-006-0137-9
更新日期：2007-01-01 00:00:00
abstract：:Connective tissue diseases, including osteogenesis imperfecta (OI) and Ehlers-Danlos syndrome (EDS), exhibit a high degree of clinical and genetic heterogeneity. We report two sisters with blue sclerae, joint hypermobility and hearing loss. Whole-exome sequencing identified two compound heterozygous ZNF469 loss-of-fun...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-020-00721-3
更新日期：2020-09-01 00:00:00
abstract：:Tumor tissue from a patient with squamous cell carcinoma of the lung and hypercalcemia has been serially implanted into athymic mice. Tumor-bearing mice develop cachexia, hypercalcemia without bone metastases, hypophosphatemia, increased urinary cyclic adenosine monophosphate (cAMP) to creatinine ratio, and undetectab...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02405367
更新日期：1984-09-01 00:00:00
abstract：:Amelogenins, the major protein components of the enamel extracellular matrix, are postulated to be involved in controlling the elongated and oriented growth of enamel carbonated apatite crystals. In order to clarify the functional role of amelogenin during the early stage of enamel biomineralization, octacalcium phosp...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-002-0011-3
更新日期：2004-06-01 00:00:00
abstract：:The type IA osteogenesis imperfecta (OI) phenotype is characterized by multiple fractures, blue sclerae, and minimal skeletal deformity without dentinogenesis imperfecta. The object of this study was to determine the effect of treatment with intravenous pamidronate (30 mg) every 3 months on bone density and bone histo...
journal_title：Calcified tissue international
pub_type： 临床试验,杂志文章
doi：10.1007/s00223-001-1055-5
更新日期：2003-02-01 00:00:00
abstract：:To compare the ability of the bone mineral density (BMD) at the distal forearm, collagen I alpha 1 (COLIA1) polymorphism, and ultrasound stiffness to identify individuals with increased risk of wrist fracture, we studied 183 postmenopausal Czech women with a wrist fracture and 178 postmenopausal controls, ages 45-70 y...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-004-0134-9
更新日期：2005-02-01 00:00:00
