Cancellous bone of the spine is greater in black women.

abstract：:Until 2006 the only mutations known to cause osteogenesis imperfecta (OI) were in the two genes coding for type I collagen chains. These dominant mutations affecting the expression or primary sequence of collagen α1(I) and α2(I) chains account for over 90% of OI cases. Since then a growing list of mutant genes causing...

journal_title：Calcified tissue international

authors： Eyre DR,Weis MA

更新日期：2013-10-01 00:00:00

abstract：:Postmenopausal osteoporosis induced by estrogen deficiency causes inadequate new bone formation and affects millions of women worldwide. Melatonin can improve bone mineral density at the femoral neck in postmenopausal women with osteopenia. This study aimed to investigate the mechanism of melatonin in estrogen deficie...

journal_title：Calcified tissue international

authors： Xu L,Zhang L,Wang Z,Li C,Li S,Li L,Fan Q,Zheng L

更新日期：2018-10-01 00:00:00

abstract：:Hip fracture may cause and/or complicate institutionalization. We undertook this study to define its overall prevalence among the residents of four nursing homes in Central Italy as well as its latency and impact on mobility when it occurred within institutions. We also performed a case control analysis with the aim o...

journal_title：Calcified tissue international

authors： Maggio D,Ubaldi E,Simonelli G,Cenci S,Pedone C,Cherubini A

更新日期：2001-06-01 00:00:00

abstract：:Regular physical activity (PA) is associated with reduced risk of the development and progression of musculoskeletal, metabolic and vascular disease. However, PA declines with age and this can contribute to multiple adverse outcomes. The aims of this study were to describe the relationship between accelerometer-determ...

journal_title：Calcified tissue international

authors： Westbury LD,Dodds RM,Syddall HE,Baczynska AM,Shaw SC,Dennison EM,Roberts HC,Sayer AA,Cooper C,Patel HP

更新日期：2018-09-01 00:00:00

abstract：:Allogenous demineralized bone matrix (DBM) represents a potential scaffold for bone tissue engineering due to its close relation in structure and function with autologous bone, but its supply is often restricted by donor availability. Thus, an expanded source of human bone is needed. The aim of this study was to evalu...

journal_title：Calcified tissue international

authors： Liu G,Sun J,Li Y,Zhou H,Cui L,Liu W,Cao Y

更新日期：2008-09-01 00:00:00

abstract：:Osteoporosis is a common age-related disease with a strong genetic influence. COLIA1 is one of the most extensively studied candidate genes and has consistently been associated with BMD and fracture. We examined the effects of the polymorphisms -1997G>T, -1663indelT, and +1245G>T and their haplotypes on vertebral frac...

journal_title：Calcified tissue international

authors： Husted LB,Harsløf T,Gonzalez-Bofill N,Schmitz A,Carstens M,Stenkjaer L,Langdahl BL

更新日期：2009-02-01 00:00:00

abstract：:The goal of this study was to find out if bone can recover after long-term administration of bisphosphonate. Disodium pamidronate (APD) was given orally by gavage to mature beagle dogs at doses of 0, 2.5, 12.5, and 25 mg/kg/day for 1 year (0.1% concentration) and the animals were allowed to recover for another year. A...

journal_title：Calcified tissue international

authors： Grynpas MD,Kasra M,Dumitriu M,Nespeca R,Very JM,Mertz BP

更新日期：1994-10-01 00:00:00

abstract：:Urinary pyridinoline (pyr) and deoxypyridinoline (dpyr) are new markers for bone resorption, and serum osteocalcin reportedly indicates osteoblastic activity. Recently, a new ultrasound bone densitometer instrument has been developed that measures ultrasonic properties of the os calcis, namely, the speed of sound (SOS...

journal_title：Calcified tissue international

authors： Kawana K,Kushida K,Takahashi M,Ohishi T,Denda M,Yamazaki K,Inoue T

更新日期：1994-12-01 00:00:00

abstract：:Human osteoblasts were obtained by migration and proliferation of cells from embryonic membranous bone on glass fragments. Light and electron microscopy analyses revealed a typical osteoblast-like appearance with high protein synthesis activity. The cells showed high alkaline phosphatase activity that was associated w...

journal_title：Calcified tissue international

authors： Oliva A,Marrone G,Della Ragione F,Riccio V,Palumbo R,Rossano F,Zappia V

更新日期：1992-11-01 00:00:00

abstract：:During endochondral ossification, proliferative activity of chondrocytes is arrested and the cells undergo terminal hypertrophic differentiation. We examined the expression of the cyclin-dependent kinase inhibitor, p21(CIP1/WAF1) in permanent cartilage (xyphoid and articular cartilage) and in cartilage undergoing endo...

journal_title：Calcified tissue international

authors： Stewart MC,Farnum CE,MacLeod JN

更新日期：1997-09-01 00:00:00

abstract：:Conventional transmission electron microscopy requires an effective dehydration of the tissue specimens under investigation. This dehydration, for which ethanol most often is used, may influence the solubility of the slightly soluble calcium phosphates. To study the behavior of calcium phosphates in ethanol, stable ne...

journal_title：Calcified tissue international

authors： Larsen MJ,Thorsen A,Jensen SJ

更新日期：1985-03-01 00:00:00

abstract：:Anemia is commonly associated with osteoporosis and sarcopenia in older persons. However, there is a common subset of patients identified as osteosarcopenic at a higher risk of adverse outcomes. Whether these patients are also at a higher risk of anemia remains unknown. In this study, we aimed to compare hemoglobin (H...

journal_title：Calcified tissue international

authors： Bani Hassan E,Vogrin S,Hernandez Viña I,Boersma D,Suriyaarachchi P,Duque G

更新日期：2020-08-01 00:00:00

abstract：:Cross-sectional and case-control studies are efficient and inexpensive approaches to the study of osteoporosis; their validity depends primarily on how the subjects are sampled. Retrospective studies of fractures may be biased if measurements change as a result of the fracture. Prospective cohort studies are less pron...

journal_title：Calcified tissue international

authors： Cummings SR

更新日期：1991-01-01 00:00:00

abstract：:Osteoporosis is characterized by low bone mass and a deterioration of bone architecture and likely is influenced by genetic factors. The ovariectomized (OVX) mouse is well suited for osteoporosis research, as shown to date by cross-sectional studies. Here, we investigate longitudinal changes by in vivo micro-computed ...

journal_title：Calcified tissue international

authors： Klinck J,Boyd SK

更新日期：2008-07-01 00:00:00

abstract：:A positional cloning effort in French Canadian families with Paget's disease of bone (PDB) resulted in the identification of a mutation in the sequestosome1 (SQSTM1) gene in a subset of both familial and sporadic PDB cases. This was confirmed in samples of mainly United Kingdom (UK) origin. In this study, we performed...

journal_title：Calcified tissue international

authors： Beyens G,Van Hul E,Van Driessche K,Fransen E,Devogelaer JP,Vanhoenacker F,Van Offel J,Verbruggen L,De Clerck L,Westhovens R,Van Hul W

更新日期：2004-08-01 00:00:00

abstract：:Synovial fluid basic calcium phosphate (BCP) crystals are associated with severe destructive arthropathy. BCP crystals induce the secretion of matrix-degrading enzymes such as collagenase. No prophylactic or therapeutic agents are recognized to ameliorate the cartilage damage associated with BCP deposits in joints. As...

journal_title：Calcified tissue international

authors： McCarthy GM,Mitchell PG,Cheung HS

更新日期：1993-06-01 00:00:00

abstract：:Hypophosphatemic rickets (HR) is a group of rare disorders caused by excessive renal phosphate wasting. The purpose of this cross-sectional study of 38 HR patients was to characterize the phenotype of adult HR patients. Moreover, skeletal and endodontic severity scores were defined to assess possible gender difference...

journal_title：Calcified tissue international

authors： Beck-Nielsen SS,Brusgaard K,Rasmussen LM,Brixen K,Brock-Jacobsen B,Poulsen MR,Vestergaard P,Ralston SH,Albagha OM,Poulsen S,Haubek D,Gjørup H,Hintze H,Andersen MG,Heickendorff L,Hjelmborg J,Gram J

更新日期：2010-08-01 00:00:00

abstract：:We compared the effects of four vitamin D metabolites, 1 alpha,25 dihydroxy vitamin D3 (1 alpha,25(OH)2D3), 1 alpha hydroxy vitamin D3 (1 alpha OH D3), 25 hydroxy vitamin D3 (25 OH D3), and 24R,25 dihydroxy vitamin D (24R,25(OH)sD3) on resorption and collagen synthesis in fetal rat bone maintained in organ culture. Re...

journal_title：Calcified tissue international

authors： Raisz LG,Kream BE,Smith MD,Simmons HA

更新日期：1980-01-01 00:00:00

abstract：:Currently used diagnostic measures for sarcopenia are based on the evaluation of appendicular skeletal muscle mass (ASMM) divided by height-squared (ASMMI). This study aimed to investigate the associations between different operational definitions of appendicular muscle mass and BMD at different skeletal sites in agin...

journal_title：Calcified tissue international

authors： Gonnelli S,Caffarelli C,Cappelli S,Rossi S,Giordano N,Nuti R

更新日期：2014-10-01 00:00:00

abstract：:Acute spinal cord injury is associated with rapid bone loss and an increased risk of fracture. In this double-blind, randomized, placebo-controlled trial, 17 patients were followed for 1 year after administration of either 4 or 5 mg of zoledronic acid or placebo. Bone mineral density (BMD) and structural analyses of t...

journal_title：Calcified tissue international

authors： Shapiro J,Smith B,Beck T,Ballard P,Dapthary M,BrintzenhofeSzoc K,Caminis J

更新日期：2007-05-01 00:00:00

abstract：:Regular exercise and physical activity (PA) are known to be protective factors for maintaining bone mineral density (BMD) and preventing osteoporotic fracture. We investigated the associations between leisure-time PA and BMD in 2,903 premenopausal and 2,267 postmenopausal women in Korea. BMDs of the lumbar spine and f...

journal_title：Calcified tissue international

authors： Kim KZ,Shin A,Lee J,Myung SK,Kim J

更新日期：2012-09-01 00:00:00

abstract：:Cost-effective intervention thresholds (ITs) based on FRAX(®) were determined for Portugal. Assuming a willingness to pay (WTP) of €32,000 per quality-adjusted life years (QALYs), treatment with generic alendronate is cost effective for men and women aged 50 years or more, with 10-year probabilities for major osteopor...

journal_title：Calcified tissue international

authors： Marques A,Lourenço Ó,Ortsäter G,Borgström F,Kanis JA,da Silva JA

更新日期：2016-08-01 00:00:00

abstract：:In the rat, prolonged administration of the luteinizing, hormone-releasing hormone agonist buserelin (25 micrograms/kg body wt/day s.c.) lowers blood estradiol, raises bone resorption, and induces osteopenia. The present study was undertaken to determine whether withdrawal of buserelin normalizes blood estradiol, slow...

journal_title：Calcified tissue international

authors： Goulding A,Gold E

更新日期：1990-01-01 00:00:00

abstract：:Ribbon-like crystals, from developing enamel of human fetuses, were studied by high resolution electron microscopy. These crystals were classically described as the first organized mineral formed during amelogenesis. They were characterized by a mean width-to-thickness ratio (W.T-1) of 9.5, and 40% were bent. On latti...

journal_title：Calcified tissue international

authors： Cuisinier FJ,Steuer P,Senger B,Voegel JC,Frank RM

更新日期：1992-10-01 00:00:00

abstract：:The recent advancement of high resolution magnetic resonance imaging has opened up new avenues for the determination of structural characteristics of the trabecular network, which may significantly improve the diagnosis of osteoporosis. An analysis of the calcaneus in healthy women has shown similar age-related change...

journal_title：Calcified tissue international

authors： Engelke K,Hahn M,Takada M,Vogel M,Ouyang X,Delling G,Genant HK

更新日期：2001-03-01 00:00:00

abstract：:Low-grade inflammation negatively affects bone. Resveratrol is a natural compound proven to possess both anti-inflammatory and bone protective properties. However, it is uncertain if the bone effects are mediated though anti-inflammatory effects. Firstly, we investigated if resveratrol affects proliferation and differ...

journal_title：Calcified tissue international

authors： Ornstrup MJ,Harsløf T,Sørensen L,Stenkjær L,Langdahl BL,Pedersen SB

更新日期：2016-08-01 00:00:00

abstract：:We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...

journal_title：Calcified tissue international

authors： Epstein S,Schlosberg M,Fallon M,Thomas S,Movsowitz C,Ismail F

更新日期：1990-09-01 00:00:00

abstract：:The effect of ascorbic acid deficiency on bone metabolism was evaluated using the ascorbate-requiring Osteogenic Disorder Shionogi (ODS) rat model. Ascorbic acid (Asc)-deficient rats gained body weight in a manner similar to Asc-supplemented rats (control) during 3 weeks, but began to lose weight during the 4th week o...

journal_title：Calcified tissue international

authors： Goto A,Tsukamoto I

更新日期：2003-08-01 00:00:00

abstract：:As tobacco smoking has been identified as a risk factor in the development of osteoporosis, possible deleterious effects of nicotine inhalation on bone mineral density (BMD) and mechanical properties of the femur in female rats were studied. Female Sprague Dawley rats were exposed to nicotine vapour 20 hours a day 5 d...

journal_title：Calcified tissue international

authors： Syversen U,Nordsletten L,Falch JA,Madsen JE,Nilsen OG,Waldum HL

更新日期：1999-09-01 00:00:00

abstract：:Calcaneus bone mineral density (BMD) of 738 Japanese women (605 healthy and 133 with osteoporosis) was measured using single X-ray absorptiometry (SXA). A reference range of calcaneus BMD values for healthy Japanese women was established and the usefulness of this method for screening and diagnosis of osteoporosis was...

journal_title：Calcified tissue international

authors： Sekioka Y,Kushida K,Yamazaki K,Inoue T

更新日期：1999-08-01 00:00:00