Bone Disease in CKD in Children.

abstract：:High serum levels of IGFBP-1 are related both to low body mass index (BMI) and to low insulin-like growth factor 1 (IGF-I), which both in turn are related to low bone mineral density (BMD) and to increased fracture risk. However, we have found no previous prospective studies on IGFBP-1 and fracture risk. Despite its n...

journal_title：Calcified tissue international

authors： Lundin H,Sääf M,Strender LE,Nyren S,Johansson SE,Salminen H

更新日期：2016-10-01 00:00:00

abstract：:We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...

journal_title：Calcified tissue international

authors： Epstein S,Schlosberg M,Fallon M,Thomas S,Movsowitz C,Ismail F

更新日期：1990-09-01 00:00:00

abstract：:The tumor-suppressor p53 is a transcription factor that regulates a number of genes in the process of cell-cycle inhibition, apoptosis, and DNA damage. Recent studies have revealed a crucial role for p53 in bone remodeling. In our previous studies we have shown that p53 is an important regulator of osteoblast differen...

journal_title：Calcified tissue international

authors： Chen H,Hays E,Liboon J,Neely C,Kolman K,Chandar N

更新日期：2011-11-01 00:00:00

abstract：:Mice deficient in the chloride channel ClC-7, which is likely involved in acidification of the resorption lacuna, display severe osteopetrosis. To fully characterize the osteopetrotic phenotype, the phenotypes of osteoclasts and osteoblasts were evaluated. ClC-7(-/-) mice and their corresponding wild-type littermates ...

journal_title：Calcified tissue international

authors： Neutzsky-Wulff AV,Karsdal MA,Henriksen K

更新日期：2008-12-01 00:00:00

abstract：:Extracellular ATP, and to a lesser extent adenosine, an ATP metabolite, stimulated cell proliferation in osteoblast-like cells (MC3T3-E1). ATP increased cytosolic Ca2+ due to Ca2+ mobilization from intracellular storage in the same concentration range of the nucleotide as that effective for DNA synthesis, suggesting t...

journal_title：Calcified tissue international

authors： Shimegi S

更新日期：1996-02-01 00:00:00

abstract：:Familial hypocalciuric hypercalcemia (FHH) is often considered in the differential diagnosis of hyperparathyroidism, but is rarely diagnosed. So far, FHH has not been documented in Israel. This report presents preliminary evidence for the occurrence of FHH in Israel. ...

journal_title：Calcified tissue international

authors： Liel Y,Arie R,Vered I

更新日期：1997-07-01 00:00:00

abstract：:Aging is associated with an increase in circulating inflammatory factors. One, the cytokine stromal cell-derived factor 1 (SDF-1 or CXCL12), is critical to stem cell mobilization, migration, and homing as well as to bone marrow stem cell (BMSC), osteoblast, and osteoclast function. SDF-1 has pleiotropic roles in bone ...

journal_title：Calcified tissue international

authors： Carbone LD,Bůžková P,Fink HA,Robbins JA,Bethel M,Hamrick MW,Hill WD

更新日期：2017-06-01 00:00:00

abstract：:A resolution-enhanced Fourier Transform Infrared (FTIR) Spectroscopic study of the CO3(2-) ion in pig enamel of increasing age and maturity has demonstrated the existence of four different, main carbonate locations. The major CO3(2-) site arises as a result of the substitution of CO3(2-) ions in the positions occupied...

journal_title：Calcified tissue international

authors： Rey C,Renugopalakrishnan V,Shimizu M,Collins B,Glimcher MJ

更新日期：1991-10-01 00:00:00

abstract：:Various studies have investigated the serum sclerostin and bone morphogenetic protein-2 (BMP-2) levels in patients with ankylosing spondylitis (AS), but the results were inconsistent. The aim of this meta-analysis was to synthetically assess the associations of serum levels of sclerostin and BMP-2 with AS. Multiple el...

journal_title：Calcified tissue international

authors： Yang J,Xu S,Chen M,Yuan Y,Zhang X,Ma Y,Wu M,Han R,Hu X,Liu R,Deng J,Guan S,Gao X,Pan M,Xu S,Shuai Z,Jiang S,Guan S,Chen L,Pan F

更新日期：2019-07-01 00:00:00

abstract：:Normative bone mineral density (BMD) and bone mineral content (BMC) values for the total body (TB), proximal femur (PF), and antero-posterior lumbar spine (LS) were obtained from a large cross-sectional sample of children and adolescents who were 8-17 years of age. There were 977 scans for the TB, 892 for the PF, and ...

journal_title：Calcified tissue international

authors： Faulkner RA,Bailey DA,Drinkwater DT,McKay HA,Arnold C,Wilkinson AA

更新日期：1996-11-01 00:00:00

abstract：:Even though indirect evidence indicates that PTH exerts an anabolic effect on dentinogenesis, the existence of PTH receptors and any second-messenger response in odontoblasts have not been demonstrated. The aim of this study was to investigate whether rat incisor odontoblasts express PTH receptors, and to identify whi...

journal_title：Calcified tissue international

authors： Lundgren T,Stenport V,Wetter A,Linde A

更新日期：1998-03-01 00:00:00

abstract：:Pregnancy and lactation-associated osteoporosis (PAO) is a rare condition with little known pathophysiology. Most cases are diagnosed in the third trimester of pregnancy or in the first weeks postpartum, particularly in first pregnancies. Vertebral fractures are most commonly observed and characterised by prolonged se...

journal_title：Calcified tissue international

authors： Grizzo FM,da Silva Martins J,Pinheiro MM,Jorgetti V,Carvalho MD,Pelloso SM

更新日期：2015-10-01 00:00:00

abstract：:Osseous tissue develops via two distinctly different processes: endochondral (EC) ossification and intramembranous (IM) ossification. The present study tests the hypothesis that each type of osseous tissue contains unique inducing factors for the promotion of cartilage and bone development. Previous work suggests that...

journal_title：Calcified tissue international

authors： Scott CK,Hightower JA

更新日期：1991-11-01 00:00:00

abstract：:The effect of SrCl(2) treatment on bone nanostructure in a rat ovariectomy model was studied using scanning small-angle X-ray scattering (sSAXS). Twelve 6-month-old female Wistar rats were used. Six animals were ovariectomized (+ovx) and six were left intact after sham surgery (-ovx). Six animals, three +ovx and three...

journal_title：Calcified tissue international

authors： Bünger MH,Oxlund H,Hansen TK,Sørensen S,Bibby BM,Thomsen JS,Langdahl BL,Besenbacher F,Pedersen JS,Birkedal H

更新日期：2010-04-01 00:00:00

abstract：:Postmenopausal osteoporosis induced by estrogen deficiency causes inadequate new bone formation and affects millions of women worldwide. Melatonin can improve bone mineral density at the femoral neck in postmenopausal women with osteopenia. This study aimed to investigate the mechanism of melatonin in estrogen deficie...

journal_title：Calcified tissue international

authors： Xu L,Zhang L,Wang Z,Li C,Li S,Li L,Fan Q,Zheng L

更新日期：2018-10-01 00:00:00

abstract：:Serum immunoreactive osteocalcin (irOC) consists of two fractions that differ from each other by their affinity for hydroxyapatite. The high and low affinity fractions are referred to as irOCbound and irOCfree, respectively. To evaluate whether these fractions are determinants for different characteristics of bone or ...

journal_title：Calcified tissue international

authors： Knapen MH,Nieuwenhuijzen Kruseman AC,Wouters RS,Vermeer C

更新日期：1998-11-01 00:00:00

abstract：:Raman spectroscopy has been used to demonstrate, for the first time, that calcium mineralization in the core of the major lateral teeth of the chiton Acanthopleura echinata takes place as an ordered process, with crystalline carbonated apatite being the first mineral deposited. Deposition begins at the top of the toot...

journal_title：Calcified tissue international

authors： Lee AP,Brooker LR,Macey DJ,van Bronswijk W,Webb J

更新日期：2000-11-01 00:00:00

abstract：:Although radiogenic free radicals are widely used as molecular probes in biological calcified tissues, their nature and their location remain controversial. In the present study we have synthesized and irradiated apatites in which 13CO3(2-) ions substitute hydroxyl or phosphate ions in hydroxyapatite. The 13C-coupling...

journal_title：Calcified tissue international

authors： Geoffroy M,Tochon-Danguy HJ

更新日期：1982-01-01 00:00:00

abstract：:Further insight into human tooth enamel, dense fraction (TE), has been obtained by following the change and loss of CO3(2-), OH-, structurally incorporated H2O, Cl-, and, indirectly, HPO4(2-) after TE had been heated in N2 or vacuum in the range 25-1000 degrees C. Quantitative infrared spectroscopic, lattice parameter...

journal_title：Calcified tissue international

authors： Holcomb DW,Young RA

更新日期：1980-01-01 00:00:00

abstract：:Conventional transmission electron microscopy requires an effective dehydration of the tissue specimens under investigation. This dehydration, for which ethanol most often is used, may influence the solubility of the slightly soluble calcium phosphates. To study the behavior of calcium phosphates in ethanol, stable ne...

journal_title：Calcified tissue international

authors： Larsen MJ,Thorsen A,Jensen SJ

更新日期：1985-03-01 00:00:00

abstract：:Interleukin (IL)-6 is a bone-resorbing cytokine that acts primarily on osteoclast progenitors to stimulate both proliferation and differentiation. Glucocorticoids (GC) down-regulate IL-6 synthesis in different cell types, including osteoblasts. Given the fact that bone remodeling is a tightly controlled process, it is...

journal_title：Calcified tissue international

authors： Dovio A,Masera RG,Sartori ML,Racca S,Angeli A

更新日期：2001-11-01 00:00:00

abstract：:The purpose of this study was to examine the effects of green tea extract (GTE) intake on bone structural and physiological properties, such as bone mass, trabecular bone microarchitecture, cortical bone geometry, and bone mechanical strength, in growing rats. Four-week-old male Wistar rats were divided into the follo...

journal_title：Calcified tissue international

authors： Minematsu A,Nishii Y,Imagita H,Sakata S

更新日期：2018-03-01 00:00:00

abstract：:The metacarpal bone mineral density (BMD) and metacarpal index (MCI) of the second metacarpal bone were measured by computed X-ray densitometry (CXD) (Teijin Ltd., Tokyo), which we have established with the development of microdensitometry of radiographs. In this study, we evaluated the basic attributes of this CXD me...

journal_title：Calcified tissue international

authors： Matsumoto C,Kushida K,Yamazaki K,Imose K,Inoue T

更新日期：1994-11-01 00:00:00

abstract：:This study revealed the distinguished changes of preferential orientation of collagen and apatite and Young's modulus in two different types of osteoporotic bones compared with the normal bone. Little is known about the bone material properties of osteoporotic bones; therefore, we aimed to assess material properties i...

journal_title：Calcified tissue international

authors： Ozasa R,Ishimoto T,Miyabe S,Hashimoto J,Hirao M,Yoshikawa H,Nakano T

更新日期：2019-04-01 00:00:00

abstract：:In the past decade there have been numerous publications reporting a significant and direct relationship between handgrip strength and bone mineral density (BMD) of the proximal femur in older adults. The present report challenges the appropriateness of the methods, and thus the conclusions used in these studies. Spec...

journal_title：Calcified tissue international

authors： Foley KT,Owings TM,Pavol MJ,Grabiner MD

更新日期：1999-04-01 00:00:00

abstract：:X-linked hypophosphatemia (XLH) is a rare, inheritable disorder manifesting as rickets in children and osteomalacia in adults. While conventional medical treatment with oral phosphate and alfacalcidol is recommended in childhood, it is undecided whether adults should continue therapy. The aim of this 6-year prospectiv...

journal_title：Calcified tissue international

authors： Shanbhogue VV,Hansen S,Jørgensen NR,Beck-Nielsen SS

更新日期：2018-03-01 00:00:00

abstract：:Monoclonal antibody against bovine serum alpha 2HS glycoprotein was raised in mice and the localization of this glycoprotein in bovine and human teeth was examined by immunohistochemical techniques on undemineralized ground sections after surface etching with dilute HCl. Positive reactions were found in both bovine an...

journal_title：Calcified tissue international

authors： Takagi Y,Shimokawa H,Suzuki M,Nagai H,Sasaki S

更新日期：1990-07-01 00:00:00

abstract：:Compressive strength index (CSI) of the femoral neck is a parameter that integrates the information of bone mineral density (BMD), femoral neck width (FNW), and body weight. CSI is considered to have the potential to improve the performance of assessment for hip fracture risk. However, studies on CSI have been rare. I...

journal_title：Calcified tissue international

authors： Yu N,Liu YJ,Pei Y,Zhang L,Lei S,Kothari NR,Li DY,Papasian CJ,Hamilton J,Cai JQ,Deng HW

更新日期：2010-10-01 00:00:00

abstract：:Although treatment with intranasal salmon calcitonin (sCT) has been shown to effectively inhibit postmenopausal bone loss, there is still controversy over both timing and the duration of its application. In an open prospective study, we therefore assessed the effect of shortterm intranasal sCT on postmenopausal bone t...

journal_title：Calcified tissue international

authors： Kraenzlin ME,Seibel MJ,Trechsel U,Boerlin V,Azria M,Kraenzlin CA,Haas HG

更新日期：1996-04-01 00:00:00

abstract：:The relationship between bisphosphonate-induced bone mineral density (BMD) gains and antifracture efficacy remains to be fully elucidated. Data from two antifracture studies were analyzed. Postmenopausal osteoporotic women received oral (2.5 mg daily, 20 mg intermittent) or intravenous (0.5 mg, 1 mg quarterly) ibandro...

journal_title：Calcified tissue international

authors： Miller PD,Delmas PD,Huss H,Patel KM,Schimmer RC,Adami S,Recker RR

更新日期：2010-10-01 00:00:00