hard tissue biochemistry: a comparison of fresh-frozen and formalin-fixed tissue samples.

abstract：:Employing a cytochemical bioassay, we compared parathyroid function in normal and X-linked hypophosphatemic (Hyp) mice. Under basal conditions Hyp mice manifested hypocalcemia and, in accord, had a plasma bioactive parathyroid hormone concentration (3.04 +/- 0.14 pg/ml) significantly greater than that of normals (2.16...

journal_title：Calcified tissue international

authors： Posillico JT,Lobaugh B,Muhlbaier LH,Drezner MK

更新日期：1985-07-01 00:00:00

abstract：:Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of woven and lamellar bone at one or more affected skeletal sites. As a result, bone pain, noti...

journal_title：Calcified tissue international

authors： Gennari L,Rendina D,Falchetti A,Merlotti D

更新日期：2019-05-01 00:00:00

abstract：:The development of prophylaxes and treatments of bone diseases that can effectively increase the strength of bone as a structure necessitates a better understanding of the time course by which chemical properties define the stiffness of the material during primary and secondary mineralization. It was hypothesized that...

journal_title：Calcified tissue international

authors： Busa B,Miller LM,Rubin CT,Qin YX,Judex S

更新日期：2005-12-01 00:00:00

abstract：:Increased bone loss has been noted in lymphoma patients; however, the incidence of hip fracture is not known. The aim of our study was to explore the risk for hip fracture in patients with lymphoma compared with the entire Swedish population. The risk of hip fracture was determined in a retrospective population cohort...

journal_title：Calcified tissue international

authors： Johansson P,Lind Kristjansdottir H,Johansson H,Jakir A,Mellström D,Lewerin C

更新日期：2020-06-01 00:00:00

abstract：:We compared indices of three-dimensional microstructure of iliac trabecular bone between 26 patients with vertebral compression fractures due to postmenopausal osteoporosis and 24 control subjects without vertebral fracture, who were matched for age, sex, race, menopausal status, and several densitometric and histolog...

journal_title：Calcified tissue international

authors： Kleerekoper M,Villanueva AR,Stanciu J,Rao DS,Parfitt AM

更新日期：1985-12-01 00:00:00

abstract：:Alkaline phosphatase is detected in both soluble and particulate fractions of rat bone. The concentration of alkaline phosphatase in the particulate fraction of rat skull cap bone and femur is high during the peak period of calcification of these bones suggesting the possibility of using it as a marker for the rate of...

journal_title：Calcified tissue international

authors： Murthy GP,Rajalakshmi R,Ramakrishnan CV

更新日期：1986-09-01 00:00:00

abstract：:The aim of this study was to investigate the relation between birth weight and calcaneal bone stiffness in a large sample of Belgian, healthy, preadolescent children. Participants were 827 children (3.6-11.2 years, 51.6 % boys) from the Belgian cohort of the IDEFICS study. Birth weight was obtained using a parental qu...

journal_title：Calcified tissue international

authors： Van den Bussche K,Michels N,Gracia-Marco L,Herrmann D,Eiben G,De Henauw S,Sioen I

更新日期：2012-10-01 00:00:00

abstract：:Hyperthyroidism and thyroid hormone substitutive therapy with serum iT3 in the normal range of values are known to lead to increased bone remodeling and loss of bone mass. We looked for a relationship between serum iT3 and bone metabolic or bone mass parameters in 402 euthyroid women aged 44-60. In a group of 93 preme...

journal_title：Calcified tissue international

authors： Schoutens A,Laurent E,Markowicz E,Lisart J,De Maertelaer V

更新日期：1991-08-01 00:00:00

abstract：:Prostaglandin E2 and leukotriene B4 are metabolites of arachidonic acid with well-characterized effects on osteoblastic cells. Prostaglandin E2 has been shown to be a potent bone-resorbing agent and to stimulate as well as inhibit osteoblastic cell proliferation. Leukotriene B4 has also been demonstrated to stimulate ...

journal_title：Calcified tissue international

authors： Ren W,Kinniburgh AJ,Dziak R

更新日期：1992-04-01 00:00:00

abstract：:The bone mineral density (BMD) of the spine was measured in the posteroanterior (PA) and lateral projections as well as the total body BMD in 447 black and white women. The lateral projection is comprised predominantly of cancellous bone whereas the total body BMD is predominantly cortical bone, and the PA spine is in...

journal_title：Calcified tissue international

authors： Aloia JF,Vaswani A,Mikhail M,Badshah M,Flaster E

更新日期：1999-07-01 00:00:00

abstract：:The solubilization of alkaline phosphatase (AP) from osteoblastic cell membranes obtained from human primary bone cell cultures was studied according to the age and sex of the donors (17 females, 11 males; age range: 2-77 years). Cell membranes were treated by non-ionic (n-octyl beta-D-glucopyranoside, OG), ionic or z...

journal_title：Calcified tissue international

authors： Bourrat C,Radisson J,Chavassieux P,Azzar G,Roux B,Meunier PJ

更新日期：2000-01-01 00:00:00

abstract：:Humanin (HN), a mitochondrial derived peptide, plays cyto-protective role under various stress. In this study, we aimed to investigate the effects of HNGF6A, an analogue of HN, on osteoblast apoptosis and differentiation and the underlying mechanisms. Cell proliferation of murine osteoblastic cell line MC3TC-E1 was ex...

journal_title：Calcified tissue international

authors： Zhu X,Zhao Z,Zeng C,Chen B,Huang H,Chen Y,Zhou Q,Yang L,Lv J,Zhang J,Pan D,Shen J,Duque G,Cai D

更新日期：2020-05-01 00:00:00

abstract：:Five years ago we reported results from a cross-sectional study of the effect of nutritional factors on calcium-regulating hormones and bone loss in perimenopausal women. We found an inverse correlation between serum 25-hydroxyvitamin D (25OHD) and immunoreactive parathyroid hormone (PTH), and we postulated that over ...

journal_title：Calcified tissue international

authors： Lukert B,Higgins J,Stoskopf M

更新日期：1992-09-01 00:00:00

abstract：:The present report compares the effects of different membrane phospholipid (PL)-cholesterol compositions on the kinetics of liposome-mediated formation of calcium phosphates from metastable solutions (2.25 mM CaCl2; 1.5 mM KH2PO4) at 22 degrees C, pH 7.4 and 240 mOsm. In most experiments, the liposomes were composed o...

journal_title：Calcified tissue international

authors： Skrtic D,Eanes ED

更新日期：1992-03-01 00:00:00

abstract：:We studied the effect of raloxifene (RAL) on arthritis and bone mineral density (BMD) in rats with collagen-induced arthritis (CIA). Seven-month-old female Sprague-Dawley rats were divided into five groups: rats without CIA (CNT), CIA rats that underwent ovariectomy (OVX) and were treated with RAL (CIA + OVX + RAL), C...

journal_title：Calcified tissue international

authors： Hayashi I,Hagino H,Okano T,Enokida M,Teshima R

更新日期：2011-02-01 00:00:00

abstract：:Several phosphoprotein preparations (phosvitin, rat incisor and fetal calf molar dentin phosphoproteins) all inhibit apatite growth/replication from pre-existing crystal seeds in metastable solutions. Two stages of the crystal growth process were inhibited by these phosphoproteins. First an initial lag period was indu...

journal_title：Calcified tissue international

authors： Termine JD,Eanes ED,Conn KM

更新日期：1980-01-01 00:00:00

abstract：:Impact activity is an important contributor to bone accrual. Children engaging in such activity have been shown to have greater bone mineral density (BMD) than their peers. This cross-sectional study was designed to quantify the association between BMD and impact activity in pre-pubescent girls, specifically examining...

journal_title：Calcified tissue international

authors： Scerpella TA,Davenport M,Morganti CM,Kanaley JA,Johnson LM

更新日期：2003-01-01 00:00:00

abstract：:Regular tennis play is associated with impressive asymmetries in bone strength in favor of the racquet arm, particularly in the humerus. However, the relative effects of service and ground strokes are not known. Serendipitously, we encountered a 46-year-old regular tennis player who has played service and ground strok...

journal_title：Calcified tissue international

authors： Ireland A,Degens H,Maffulli N,Rittweger J

更新日期：2015-08-01 00:00:00

abstract：:The purpose of this study was to determine whether human parathyroid hormone (h-PTH) enhances trabecular bone mass and connectivities that were reduced by streptozotocin (STZ)-induced diabetes in rats. Seven-month-old female Wistar rats were injected with STZ or its vehicle intraperitoneally. All vehicle-injected norm...

journal_title：Calcified tissue international

authors： Tsuchida T,Sato K,Miyakoshi N,Abe T,Kudo T,Tamura Y,Kasukawa Y,Suzuki K

更新日期：2000-03-01 00:00:00

abstract：:This study examines the efficacy of using radiolabeled thymidine as a measure of bone cell DNA synthesis. The effect of a bone-active peptide on cell proliferation is assessed under different labeling conditions and it is shown that the apparent stimulation in DNA synthesis is due to an increase in participating cells...

journal_title：Calcified tissue international

authors： Puzas JE,Brand JS

更新日期：1986-08-01 00:00:00

abstract：:We conducted a case-control study on fracture risk associated with the use of orally administered prednisolone/prednisone, budesonide, methylprednisolone, and hydrocortisone to assess if the various preparations were associated with different fracture patterns. Cases were all subjects with any fracture sustained durin...

journal_title：Calcified tissue international

authors： Vestergaard P,Rejnmark L,Mosekilde L

更新日期：2008-04-01 00:00:00

abstract：:Parathyroid Hormone (PTH) stimulates calcium entry into bone cells in vitro, and this effect has been proposed to mediate the actions of PTH on bone. Using cells harvested from infant rat calvaria by collagenase digestion, we evaluated the sensitivity and specificity of this phenomenon. Calcium uptake was temperature ...

journal_title：Calcified tissue international

authors： Marcus R,Orner FB

更新日期：1980-01-01 00:00:00

abstract：:The acute-phase response (APR) is frequently observed in patients treated with intravenous (iv) zoledronate (ZOL). We investigated whether a short course of rosuvastatin (ROSU) could attenuate the ZOL--induced APR through blocking the mevalonate pathway at a proximal level. Twenty-eight osteoporotic postmenopausal wom...

journal_title：Calcified tissue international

authors： Makras P,Anastasilakis AD,Polyzos SA,Bisbinas I,Sakellariou GT,Papapoulos SE

更新日期：2011-05-01 00:00:00

abstract：:Teriparatide (TPTD) is known to increase the cortical thickness and porosity. The purpose of the present study was to determine whether switching from TPTD to ibandronate (IBN) would be useful for improving cortical bone parameters as assessed using high-resolution quantitative computed tomography (HR-QCT) analyses in...

journal_title：Calcified tissue international

authors： Iwamoto J,Seki A,Nango N

更新日期：2016-11-01 00:00:00

abstract：:The effect of teriparatide treatment on microdamage accumulation has yet to be examined in animal studies. The purpose of this study was to investigate the effect of once-weekly teriparatide treatment on bone microdamage accumulation and the relationship between microdamage parameters and bone mass, architecture, turn...

journal_title：Calcified tissue international

authors： Yoshitake S,Mashiba T,Saito M,Fujihara R,Iwata K,Takao-Kawabata R,Yamamoto T

更新日期：2019-04-01 00:00:00

abstract：:The aim of this study was to determine whether forearm bone mineral density (BMD) measurements are affected by clinical risk factors for osteoporosis to the same extent as spine and hip BMD. The study population consisted of 1,009 female patients and volunteers, of whom 238 were premenopausal. Women were placed into s...

journal_title：Calcified tissue international

authors： Patel R,Blake GM,Fogelman I

更新日期：2007-02-01 00:00:00

abstract：:Molybdenum (Mo), at high concentrations, induces changes in the epiphyseal growth plate through its effects on copper (Cu) metabolism but it is unclear whether or not Mo can induce changes independent of its effects on copper status. To this end, the effect of Mo on longitudinal bone growth was examined in rats. Dieta...

journal_title：Calcified tissue international

authors： Parry NM,Phillippo M,Reid MD,McGaw BA,Flint DJ,Loveridge N

更新日期：1993-09-01 00:00:00

abstract：:The absorption kinetics of intranasal salmon calcitonin were assessed in 4 normal subjects and 9 patients with Klinefelter's syndrome. After administration, absorption occurred within 5 minutes. There was a highly significant correlation between the amount administered and the amount absorbed (r = -0.83, P less than 0...

journal_title：Calcified tissue international

authors： Pun KK,Chan LW,Lau P,Ho PW,Wang C

更新日期：1990-02-01 00:00:00

abstract：:Various studies have investigated the serum sclerostin and bone morphogenetic protein-2 (BMP-2) levels in patients with ankylosing spondylitis (AS), but the results were inconsistent. The aim of this meta-analysis was to synthetically assess the associations of serum levels of sclerostin and BMP-2 with AS. Multiple el...

journal_title：Calcified tissue international

authors： Yang J,Xu S,Chen M,Yuan Y,Zhang X,Ma Y,Wu M,Han R,Hu X,Liu R,Deng J,Guan S,Gao X,Pan M,Xu S,Shuai Z,Jiang S,Guan S,Chen L,Pan F

更新日期：2019-07-01 00:00:00

abstract：:This study examined effects of bone bonding and nonbonding implants on parameters associated with matrix vesicle-mediated primary bone formation, matrix vesicle alkaline phosphatase and phospholipase A2 specific activities, and phosphatidylserine content. Tibia marrow ablation followed by implantation of KG-Cera, Mina...

journal_title：Calcified tissue international

authors： Schwartz Z,Swain LD,Marshall T,Sela J,Gross U,Amir D,Muller-Mai C,Boyan BD

更新日期：1992-12-01 00:00:00