Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat.

abstract：:The effects of divalent and trivalent cations on the gamma-aminobutyric acid (GABA)-induced chloride current were studied with rat dorsal root ganglion neurons in primary culture using the whole-cell configuration of the patch-clamp technique. Lanthanum (La3+) reversibly potentiated the GABA-induced current with a hal...

journal_title：Brain research

authors： Ma JY,Narahashi T

更新日期：1993-04-02 00:00:00

abstract：:Although dendritic release was first proposed in the 1970s, the mechanism of release is still subject to debate. We have used in vivo microdialysis to study the acute effects of botulinum toxin A, B and tetanus toxin injected in the substantia nigra or striatum of freely moving rats. Spontaneous and evoked dopamine re...

journal_title：Brain research

authors： Bergquist F,Niazi HS,Nissbrandt H

更新日期：2002-09-20 00:00:00

abstract：:The present study examined the effect of chronic paroxetine (10 mg/kg p.o., 21 days) on the 5-HT1B and 5-HT1D autoreceptors controlling 5-HT efflux in slices of rat ventrolateral geniculate nucleus. Electrically stimulated 5-HT efflux (10 pulses, 200 Hz, 0.1 ms, 10 mA) was measured using fast cyclic voltammetry. Peak ...

journal_title：Brain research

authors： Davidson C,Stamford JA

更新日期：1997-06-20 00:00:00

abstract：:Suppression of geniculate ponto-geniculo-occipital (PGO) waves was achieved in kittens by performing bilateral mesencephalic lesions of the PGO pathways. Sleep-wake parameters and the spontaneous unit activity in the lateral geniculate nucleus (LGN) were then chronically recorded during one month after the lesions. Wh...

journal_title：Brain research

authors： Davenne D,Adrien J

更新日期：1987-04-14 00:00:00

abstract：:Unitary discharges in the efferent ciliary nerves were studied in cervical sympathectomized rabbits. In all, 279 units were recorded and categorized, except 7 units, into the following 3 types from their responses to photic and other stimuli, i.e. type A (170 units), type B (42 units) and type C (60 units). Type A uni...

journal_title：Brain research

authors： Inoue T

更新日期：1980-03-17 00:00:00

abstract：:A novel and convenient assay was used to determine the effect of recombinant Interleukin-2 (IL-2) on the function of the blood-brain barrier (BBB). The assay is based on a variant of the West Nile virus, WN-25, which had lost its neuroinvasiveness but not its neurovirulence. WN-25, when injected intravenously, can cau...

journal_title：Brain research

authors： Kobiler D,Lustig S,Gozes Y,Ben-Nathan D,Akov Y

更新日期：1989-09-04 00:00:00

abstract：:The terminal areas and cells of origin of the projection from the dorsal column nuclei to the mesencephalon were investigated by the intra-axonal transport method. Following injection of wheat germ agglutinin-horseradish peroxidase conjugate into the dorsal column nuclei, anterograde labeling was observed in several r...

journal_title：Brain research

authors： Wiberg M,Blomqvist A

更新日期：1984-10-08 00:00:00

abstract：:Seasonally breeding animals undergo numerous physiological changes in response to changes in the length of the photoperiod. In most warm-weather breeding rodents, these changes result in reproductive quiescence during short photoperiods. It has been hypothesized that this change is mediated by changes in the activity ...

journal_title：Brain research

authors： Mintz EM,Lavenburg KR,Blank JL

更新日期：2007-11-14 00:00:00

abstract：:In a study of the capacity of neural grafts to promote functional recovery in rats with fimbria-fornix lesions, 5 groups of rats were studied behaviourally and with acetylcholinesterase (AChE) histochemistry: (1) sham-operated controls; (2) bilateral fimbria-fornix lesions; (3) bilateral lesions plus bilateral solid e...

journal_title：Brain research

authors： Dunnett SB,Low WC,Iversen SD,Stenevi U,Björklund A

更新日期：1982-11-18 00:00:00

abstract：:MicroRNAs (miRNAs) are short, non-coding RNAs that negatively regulate target gene expression, and play an important role in cerebral ischemic injury. MiR-146a has been reported to be highly related to cell invasion, metastasis, immunity, inflammation and apoptosis. Previous studies have indicated that miR-146a can ei...

journal_title：Brain research

authors： Zhou X,Su S,Li S,Pang X,Chen C,Li J,Liu J

更新日期：2016-10-01 00:00:00

abstract：:To evaluate roles of the sympathetic nervous system in enhancing glucose uptake in skeletal muscles in response to electrical stimulation of the ventromedial hypothalamic nucleus (VMH), the effects of guanethidine treatment and adrenal demedullation on the response were examined in rats anesthetized and injected with ...

journal_title：Brain research

authors： Minokoshi Y,Okano Y,Shimazu T

更新日期：1994-06-27 00:00:00

abstract：:Glutamate (2.5 mg) was administered after the blood-brain barrier had been opened by a unilateral intracarotid infusion of 5 mg protamine sulfate in rats. Whereas the brain specific gravity, measured 24 h later, did not differ between the injected and non-injected side after protamine alone, glutamate significantly re...

journal_title：Brain research

authors： Westergren I,Johansson BB

更新日期：1992-02-28 00:00:00

abstract：:The in vitro capacity of sympathetic superior cervical ganglia (SCG) to take up [3H]choline from the extracellular medium, to synthesize acetylcholine from [3H]choline, and to release [3H]acetylcholine in response to a high K+ concentration, were examined in rats throughout a 24-h cycle. Both the release of [3H]acetyl...

journal_title：Brain research

authors： González Burgos GR,Rosenstein RE,Cardinali DP

更新日期：1994-02-14 00:00:00

abstract：:Neurotransmitter effects were studied on in vitro release of immunoreactive somatostatin (SRIF) from slices prepared from several regions of the rat brain: mediobasal hypothalamus (MBH), preoptic anterior hypothalamic area (POA) and amygdaloid complex (AMY). Potassium (K+, 56 mM) stimulated SRIF release in all structu...

journal_title：Brain research

authors： Epelbaum J,Tapia-Arancibia L,Kordon C

更新日期：1981-06-29 00:00:00

abstract：:Two categories of large neurons--fusiform cells and giant cells--can be distinguished in the dorsal cochlear nucleus of the hamster. In the adult, these neurons are located in separate laminae in the nucleus and have distinct dendritic morphology. However, the two cell types are not distinguishable in the newborn hams...

journal_title：Brain research

authors： Schweitzer L,Cant NB

更新日期：1985-05-01 00:00:00

abstract：:Previous studies have suggested that monosynaptic transmission between spinal primary afferent fibers and motoneurons is mediated by an excitatory amino acid, most likely glutamate or aspartate. No such comparable studies have been carried out in the trigeminal system. In an attempt to elucidate the neurotransmitter(s...

journal_title：Brain research

authors： Chandler SH

更新日期：1989-01-16 00:00:00

abstract：:We examined the distribution of choline acetyltransferase (ChAT) mRNA in the brain of six autopsied individuals by in situ hybridization with 35S-labeled human ChAT riboprobes. Neurons containing hybridization signal for ChAT mRNA were observed in the nucleus of the diagonal band of Broca, the basal nucleus of Meynert...

journal_title：Brain research

authors： Kasashima S,Muroishi Y,Futakuchi H,Nakanishi I,Oda Y

更新日期：1998-09-21 00:00:00

abstract：:Quantitative morphological techniques have revealed several new aspects of the action of the Staggerer mutant gene. Staggerer is an autosomal recessive gene which causes ataxia and severe malformation of the cerebellar cortex in mice. The Purkinje cells of the cerebellar cortex are small, abnormal in morphology and re...

journal_title：Brain research

authors： Roffler-Tarlov S,Herrup K

更新日期：1981-06-29 00:00:00

abstract：:Superior cervical ganglionectomy (SCGx) has drastic effects on numerous hormonal circadian rhythms and particularly on pineal melatonin secretion. We investigated the hormonal consequences of ablation of the superior cervical ganglion on the corticotropic circadian rhythms in the male rat. Plasma were obtained by samp...

journal_title：Brain research

authors： Siaud P,Mekaouche M,Maurel D,Givalois L,Ixart G

更新日期：1994-08-01 00:00:00

abstract：:Correlative light and electron microscopic immunohistochemical methods were adapted for a descriptive analysis of the normal time course and pattern of expression and intraneuronal localization of the enzyme glutamic acid decarboxylase (GAD) in the neostriatum (Ns) of fetal, postnatal and adult cats. The differentiati...

journal_title：Brain research

authors： Fisher RS,Levine MS,Adinolfi AM,Hull CD,Buchwald NA

更新日期：1987-06-01 00:00:00

abstract：:The discontinuous terminal distributions of thalamo- and nigrostriatal axons were examined in adjacent tissue sections from single cat brains by combined anterograde labeling with tritiated proline autoradiography and wheat germ-horseradish peroxidase histochemistry. Injection of one tracer into the centromedian-paraf...

journal_title：Brain research

authors： Beckstead RM

更新日期：1985-05-27 00:00:00

abstract：:Long-term memory formation for passive-avoidance learning in the day-old chick is known to have two distinct time windows of protein synthesis (F.M. Freeman, S.P.R. Rose, A.B. Scholey, 1995. Two time windows of anisomycin-induced amnesia for passive-avoidance training in the day-old chick. Neurobiol. Learn. Mem. 63, 2...

journal_title：Brain research

authors： Freeman FM,Young IG

更新日期：2000-05-12 00:00:00

abstract：:The pre- and postsynaptic elements of the calyx-type synapse in the chick ciliary ganglion were stained with Lucifer yellow in situ, and the structure of this synapse was examined after enzymatic dissociation of the ganglion. Back-staining of the ciliary nerve resulted in darkly stained neuronal cell bodies. Foreward-...

journal_title：Brain research

authors： Stanley EF

更新日期：1987-09-22 00:00:00

abstract：:Growth of cultured N1E-115 neuroblastoma cells in 1 microM A23187 for 2 days to elevate internal Ca reduced both membrane Na current and the transient, but not steady state, component of outward K current. Na channel mRNA abundance was reduced by an average value of 45% without effect on Kv3.1. Increases in internal C...

journal_title：Brain research

authors： Hirsh JK,Quandt FN

更新日期：1996-01-15 00:00:00

abstract：:Medium conditioned by NG108-15 neuroblastoma x glioma hybrid cells contains a factor which increases the number of acetylcholine receptor (AChR) aggregates on cultured myotubes. Protease digestion indicates that the AChR aggregation factor is a protein, and the molecular weight is from 150,000 to 250,000 daltons as es...

journal_title：Brain research

authors： Bauer HC,Daniels MP,Pudimat PA,Jacques L,Sugiyama H,Christian CN

更新日期：1981-03-30 00:00:00

abstract：:Significant insights into the dynamics of neuronal populations have been gained in the olfactory system where rich spatio-temporal dynamics is observed during, and following, exposure to odours. It is now widely accepted that odour identity is represented in terms of stimulus-specific rate patterning observed in the c...

journal_title：Brain research

authors： Buckley CL,Nowotny T

更新日期：2012-01-24 00:00:00

abstract：:Although nitric oxide (NO) has been shown to play an important role in the pathophysiology of cerebral ischemia, its contribution to the pathogenesis of experimentally induced thromboembolic stroke is unknown. In this study, we pharmacologically manipulated NO levels in the acute post-thrombotic stage and determined t...

journal_title：Brain research

authors： Stagliano NE,Dietrich WD,Prado R,Green EJ,Busto R

更新日期：1997-06-06 00:00:00

abstract：:Discrete axon-sparing lesions were placed unilaterally in the mesencephalon by the local injection of kainic acid. Unilateral lesions of the dorsal reticular formation just beneath the superior colliculus and lateral to the periacqueductal grey resulted in consistent ipsiversive apomorphine-induced circling. Only weak...

journal_title：Brain research

authors： Mulas A,Longoni R,Spina L,Del Fiacco M,Di Chiara G

更新日期：1981-03-16 00:00:00

abstract：:Previously, we had shown that ammonium chloride (ammonia)-induced accumulation of cyclic GMP in the microdialysates of rat striatum is blocked by taurine. In this study, coinfusion with taurine of a GABAA receptor antagonist bicuculline or a glycine receptor antagonist strychnine (100 microM each), separately, restore...

journal_title：Brain research

authors： Hilgier W,Oja SS,Saransaari P,Albrecht J

更新日期：2005-05-10 00:00:00

abstract：:The effects of the GABAA agonist, isoguvacine, on NMDA-induced burst firing of substantia nigra dopaminergic neurons were studied with intracellular and whole cell recordings in vitro. NMDA application caused the neurons to fire in rhythmic bursts. Although the NMDA-induced bursty firing pattern was insensitive to hyp...

journal_title：Brain research

authors： Paladini CA,Iribe Y,Tepper JM

更新日期：1999-06-19 00:00:00