Effect of phencyclidine (PCP) on blood pressure and catecholamine levels in discrete brain nuclei.

abstract：:Olfactory nerve input is required for the normal expression of tyrosine hydroxylase (TH) by dopaminergic neurons in the glomerular region of the rodent main olfactory bulb. To determine whether the olfactory nerve exerts a similar influence on neurons in other brain regions, we performed unilateral bulbectomies in rat...

journal_title：Brain research

authors： Guthrie KM,Leon M

更新日期：1989-09-11 00:00:00

abstract：:Chronic hydrocephalus is one of the severe complications after subarachnoid hemorrhage (SAH). However, there is no efficient treatment for the prevention of chronic hydrocephalus, partially due to poor understanding of underlying pathogenesis, subarachnoid fibrosis. Transforming growth factor-β1(TGF-β1) is a potent fi...

journal_title：Brain research

authors： Yan H,Chen Y,Li L,Jiang J,Wu G,Zuo Y,Zhang JH,Feng H,Yan X,Liu F

更新日期：2016-01-01 00:00:00

abstract：:We previously reported that angiotensin II type 2 (AT(2)) receptor signaling prevents neural damage and cognitive impairment after focal cerebral ischemia. We investigated the possible roles of the AT(2) receptor in the sex difference, focusing on cognitive function and ischemic brain damage using AT(2) receptor-defic...

journal_title：Brain research

authors： Sakata A,Mogi M,Iwanami J,Tsukuda K,Min LJ,Fujita T,Iwai M,Ito M,Horiuchi M

更新日期：2009-12-01 00:00:00

abstract：:Patients with Parkinson's disease (PD) manifest difficulty in initiation and execution of movements, particularly when movements are sequential, simultaneous or repetitive. Eye movements are particularly effective in evaluating motor impairments. We utilized a series of saccadic eye movement paradigms to explore the a...

journal_title：Brain research

authors： Winograd-Gurvich C,Georgiou-Karistianis N,Fitzgerald PB,Millist L,White OB

更新日期：2006-08-23 00:00:00

abstract：:The patch clamp technique has been used to study ion channel activity in the apical (ventricular) membrane of epithelial cells from the rat choroid plexus. Two different classes of Cl(-)-selective channel were identified. A low conductance (26 pS) channel which was the predominant feature in cell-attached and inside-o...

journal_title：Brain research

authors： Garner C,Brown PD

更新日期：1992-09-18 00:00:00

abstract：:Visual pathways (optic disc, optic nerve and pretectal regions) were electrically stimulated and evoked potentials were explored throughout the inferior olive in the anesthetized rat. Responsive areas were identified as the caudal half of the dorsal cap, nucleus beta and the most caudal region of subnucleus c of the m...

journal_title：Brain research

authors： Akaike T

更新日期：1986-03-12 00:00:00

abstract：:The action of the epileptogenic agent pentylenetetrazol (PTZ) on a cloned potassium channel of the rat brain was studied. The Kv1.1 channel was expressed in oocytes of Xenopus laevis and potassium currents were investigated in outside-out and inside-out membrane patches. The results show that PTZ increased the multi-c...

journal_title：Brain research

authors： Madeja M,Musshoff U,Lorra C,Pongs O,Speckmann EJ

更新日期：1996-05-25 00:00:00

abstract：:The influence of the cortico-geniculate pathway on identified X and Y lateral geniculate cells was studied by reversibly cooling visual cortical areas 17 and 18. The majority (86.5%) of cells changed their response to visual stimulation when cortex was inactivated, and both X- and Y-cells were modulated by the cortica...

journal_title：Brain research

authors： Geisert EE,Langsetmo A,Spear PD

更新日期：1981-03-16 00:00:00

abstract：:Injection of a potent, cholinergic muscarinic antagonist, [3H]3-quinuclidinyl benzilate ([3H]QNB), results in a localization of the drug to muscarinic receptors in rat brain. The distribution of these drug receptors was examined in various brain regions previously thought to contain cholinergic neurons. They were loca...

journal_title：Brain research

authors： Kuhar M,Yamamura HI

更新日期：1976-07-09 00:00:00

abstract：:Growth hormone releasing factor (GRF) applied by iontophoresis, pressure, and in the perfusate, increased (14.81%) or decreased (45.92%) the firing of paraventricular neurons extracellularly recorded from guinea-pig hypothalamic slices. Effects were similar whatever the mode of application and were elicited in the nan...

journal_title：Brain research

authors： Poulain P,Carette B

更新日期：1986-04-23 00:00:00

abstract：:Metabolic stress imposed by epileptic seizures can result in mitochondrial dysfunction, believed to act as positive feedback on epileptogenesis and seizure susceptibility. As the mechanism behind this positive feedback is unclear, the aim of the present study was to investigate the causal link between acute mitochondr...

journal_title：Brain research

authors： Andreasen M,Nedergaard S

更新日期：2021-01-15 00:00:00

abstract：:Extracellular amino acids were followed in the hippocampus during sustained seizures induced by systemic administration of kainic acid (KA) or bicuculline (BC). KA epilepsy was associated with marked increases in phosphoethanolamine (PEA) and taurine. Alanine and ethanolamine were moderately raised while other amino a...

journal_title：Brain research

authors： Lehmann A,Hagberg H,Jacobson I,Hamberger A

更新日期：1985-12-16 00:00:00

abstract：:Increased alcohol consumption and heightened aggression have been linked to social isolation. Furthermore, animals treated with alcohol following social separation showed higher aggression together with lower serotonin transmission. Although reduced serotonin transmission in the brain may be related to alcohol-induced...

journal_title：Brain research

authors： Mamiya PC,Matray-Devoti J,Fisher H,Wagner GC

更新日期：2017-05-01 00:00:00

abstract：:'Feedback' signals from mammalian extrastriate visual cortices are reported to exert primarily an excitatory influence on the classical receptive field (CRF) of neurons in the primary visual cortex (V1). However, given the much larger CRFs of neurons in extrastriate visual cortices it is not yet understood how feedbac...

journal_title：Brain research

authors： Wang C,Huang JY,Bardy C,FitzGibbon T,Dreher B

更新日期：2010-04-30 00:00:00

abstract：:[d-Ala(2)-d-Leu(5)]-Enkephalin (DADLE) has shown promising results in protecting neurons from damages. However, the mechanism for this protection is still under investigation. The current study was carried out to test the hypothesis that DADLE may regulate cellular transcription in neurons. SH-SY5Y cells and primary c...

journal_title：Brain research

authors： Tian J,Gu Y,Sun K,Wang B,Chen J,Wang X,Su D

更新日期：2014-05-27 00:00:00

abstract：:Transependymal absorption of cerebrospinal fluid (CSF) in hydrocephalus is suggested by periventricular edema, but the necessary bulk flow of interstitial fluid (ISF) has not been found. We performed ventriculocisternal perfusions in adult cats using CSF with the extracellular marker [3H]sucrose. CSF pressure was main...

journal_title：Brain research

authors： Rosenberg GA,Kyner WT,Estrada E

更新日期：1982-01-28 00:00:00

abstract：:Rats were anesthetized with a continuous infusion of pentobarbital. First we showed that electroacupuncture (EA) suppressed the tail flick nociceptive reflex. Naltrexone (a long acting opiate antagonist) was given either intravenously or intrathecally to attempt to block this EA effect. The naltrexone prevented this E...

journal_title：Brain research

authors： Pomeranz B,Bibic L

更新日期：1988-06-14 00:00:00

abstract：:Traumatic injury to the peripheral and central nervous systems very often causes axotomy, where an axon loses connections with its target resulting in loss of function. The axon segments distal to the injury site lose connection with the cell body and degenerate. Axotomized neurons in the periphery can spontaneously m...

journal_title：Brain research

authors： Smith TP,Sahoo PK,Kar AN,Twiss JL

更新日期：2020-08-01 00:00:00

abstract：:Portions of cerebellar cortex, particularly Larsell's hemisphere VI, have been identified as involved but not essential for the acquisition and retention of classical conditioning of the nictitating membrane (NM) response in rabbit. The present experiment was undertaken to examine the effect of lesions of cerebellar c...

journal_title：Brain research

authors： Woodruff-Pak DS,Lavond DG,Logan CG,Steinmetz JE,Thompson RF

更新日期：1993-04-09 00:00:00

abstract：:Ischemic stroke is caused by the interruption of cerebral blood flow that leads to brain damage with long-term sensorimotor deficits. Stem cell transplantation may recover functional deficit by replacing damaged brain. In this study, we attempted to test whether the human neural stem cells (NSCs) can improve the outco...

journal_title：Brain research

authors： Chu K,Kim M,Park KI,Jeong SW,Park HK,Jung KH,Lee ST,Kang L,Lee K,Park DK,Kim SU,Roh JK

更新日期：2004-08-06 00:00:00

abstract：:The retinofugal projections in the shark, Hemiscyllium plagiosum were studied after unilateral eye injection of tritiated proline. The results showed that each eye in this animal projects not only to the contralateral side of the brain but also to several ipsilateral visual centers including the nucleus suprachiasmati...

journal_title：Brain research

authors： Jen LS,So KF,Yew DT,Lee M

更新日期：1983-09-05 00:00:00

abstract：:Lamprey retriculospinal neurons show phasic oscillations of their membrane potential during fictive locomotion. This modulation originates from the spinal cord locomotor networks. The aim of the present study was to elucidate the pattern of discharge of the spino-bulbar axons responsible for this modulation. Experimen...

journal_title：Brain research

authors： Vinay L,Grillner S

更新日期：1992-06-05 00:00:00

abstract：:A study of seizure activity and neuronal cell death produced by intracerebroventricular kainic acid had suggested that seizures conveyed by the hippocampal mossy fibers are more damaging to CA3 pyramidal cells than seizures conveyed by other pathways. To test this idea, the effects of a unilateral mossy fiber lesion w...

journal_title：Brain research

authors： Vicedomini JP,Nadler JV

更新日期：1990-03-26 00:00:00

abstract：:We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...

journal_title：Brain research

authors： Uzakov SS,Ivanov AD,Salozhin SV,Markevich VA,Gulyaeva NV

更新日期：2015-10-22 00:00:00

abstract：:NMDA receptor activation leads to elevated Ca2+ in cultured rat cortical and retinal ganglion cell neurons. If excessive, this Ca2+ response is associated with delayed neurotoxicity. We used dantrolene and ionomycin to test if the Ca2+ response to NMDA was due to mobilization of intracellular Ca2+ stores rather than m...

journal_title：Brain research

authors： Lei SZ,Zhang D,Abele AE,Lipton SA

更新日期：1992-12-11 00:00:00

abstract：:It has been shown that 2-deoxy-D-glucose (2-DG) inhibits glucose utilization and elicits feeding through the lateral hypothalamus. In contrast, 2,5-anhydro-D-mannitol (2,5-AM), blocking glycogenolysis and/or gluconeogenesis, elicits feeding through the ventromedial hypothalamus. The aim of the present study was to det...

journal_title：Brain research

authors： Morita H,Fujimoto K,Sakata T,Kurokawa M,Yoshimatsu H,Noda T,Iwakiri R,Sakai T

更新日期：1996-05-06 00:00:00

abstract：:Adult Sprague-Dawley rats were exposed to a single session of 100 inescapable tail shocks (IS). Bromodeoxyuridine (BrdU) was administered 1 h, 2 days or 7 days later and hippocampal cell proliferation (CP) was assessed after a 2-h survival period. Measures of plasma corticosterone (CORT) levels were also obtained. Des...

journal_title：Brain research

authors： Fornal CA,Stevens J,Barson JR,Blakley GG,Patterson-Buckendahl P,Jacobs BL

更新日期：2007-01-26 00:00:00

abstract：:The olivary pretectal nucleus is a primary visual centre sensitive to luminance changes. It is involved in the pupillary light reflex, the consensual pupillary light reflex and related reflexes, such as the lid closure reflex whereby pupillary constriction takes place. Since the olivary pretectal nucleus is a small nu...

journal_title：Brain research

authors： Klooster J,Vrensen GF,Müller LJ,van der Want JJ

更新日期：1995-08-07 00:00:00

abstract：:The intracellular injection technique of HRP with simultaneous recordings of intracellular potential was applied to the crab X-organ-sinus gland peptidergic neurosecretory neurons. At least two classes of neurons were discriminated from the usual type of neurosecretory neurons morphologically as well as electrophysiol...

journal_title：Brain research

authors： Nagano M

更新日期：1986-01-08 00:00:00

abstract：:Sex hormone binding globulin (SHBG) is produced in brain where it is often co-localized with oxytocin. Infusions of SHBG into the medial preoptic area-anterior hypothalamus facilitate female sexual receptivity. SHBG has receptors on plasma membranes of the prostate gland where binding of the 5alpha-reduced androgen di...

journal_title：Brain research

authors： Caldwell JD,Höfle S,Englöf I

更新日期：2002-09-06 00:00:00