Neural correlates of levels of emotional awareness during trauma script-imagery in posttraumatic stress disorder.

Abstract:

OBJECTIVE:To examine individual differences in levels of emotional awareness as a predictor of the blood oxygenation level dependent (BOLD) response to trauma script-driven imagery in trauma-exposed individuals with (n = 25) and without (n = 16) posttraumatic stress disorder (PTSD). METHODS:Participants completed the Levels of Emotional Awareness Scale (LEAS) and a functional magnetic resonance imaging trauma script-driven imagery paradigm. RESULTS:Patients with PTSD exhibited lower LEAS scores in comparison with the control group. LEAS scores correlated positively with BOLD activity during trauma script-imagery in the ventral anterior cingulate cortex (vACC) in healthy controls, whereas LEAS scores correlated negatively with activation of vACC in individuals with PTSD. CONCLUSION:Patients with PTSD exhibit lower than average levels of emotional awareness. Levels of emotional awareness are differentially associated with vACC response during trauma script-driven imagery in healthy controls versus individuals with PTSD.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Frewen P,Lane RD,Neufeld RW,Densmore M,Stevens T,Lanius R

doi

10.1097/PSY.0b013e31815f66d4

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

27-31

issue

1

eissn

0033-3174

issn

1534-7796

pii

PSY.0b013e31815f66d4

journal_volume

70

pub_type

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