Abstract:
OBJECTIVES:Exposure to child abuse (CA) is associated with an increased risk of developing asthma and allergies; it is unknown if that risk is present across generations. This study investigated if 2-year-old children born to mothers with a history of CA were at an increased risk of receiving a diagnosis of asthma or allergies. METHODS:Data from 1,551 participants were collected as part of the All Our Babies (AOB) study, a prospective pregnancy cohort. During pregnancy, each woman provided information about her own history of CA, and at 24 months postpartum, she provided information about her child's medical diagnoses. Symptoms of maternal depression and anxiety were assessed during pregnancy and at 24 months postpartum. RESULTS:Unadjusted models showed that compared to children born to mothers without a history of CA, 2-year-old children born to mothers with a history of CA were more likely to have had a diagnosis of asthma (7.4% vs 4.2%, p = .016) or allergy (15.6% vs 9.2%, p < .001). Maternal symptoms of depression assessed in late pregnancy and symptoms of depression and anxiety at 24 months postpartum were significant mediators of the relationship between maternal CA and 2-year-old asthma diagnosis. Maternal symptoms of depression and anxiety assessed in late pregnancy were also significant mediators of the relationship between maternal CA and 2-year-old allergy diagnosis. CONCLUSIONS:The results indicate that maternal exposure to CA is associated with increased risk of asthma and allergy in their 2-year-old children; symptoms of maternal depression and anxiety were identified as pathways linking the variables.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Tomfohr-Madsen LM,Bayrampour H,Tough Sdoi
10.1097/PSY.0000000000000419subject
Has Abstractpub_date
2016-11-01 00:00:00pages
1031-1042issue
9eissn
0033-3174issn
1534-7796journal_volume
78pub_type
杂志文章abstract:OBJECTIVE:Although the association between depression and the incidence of coronary heart disease has been established in many studies, the impact of depression on the incidence of heart failure has not been previously investigated. METHODS:We examined the effect of depression (assessed by means of the Center for Epid...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200201000-00002
更新日期:2002-01-01 00:00:00
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journal_title:Psychosomatic medicine
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/00006842-199807000-00010
更新日期:1998-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
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pub_type: 评论,社论
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更新日期:2016-05-01 00:00:00
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更新日期:2009-07-01 00:00:00
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更新日期:2006-09-01 00:00:00
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更新日期:2019-11-01 00:00:00
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更新日期:1987-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/01.psy.0000024235.11538.9a
更新日期:2002-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/00006842-200105000-00012
更新日期:2001-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
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更新日期:2014-10-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1097/PSY.0b013e3182757b2b
更新日期:2013-01-01 00:00:00
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doi:10.1097/00006842-199407000-00003
更新日期:1994-07-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2009-02-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2019-04-01 00:00:00
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更新日期:2004-05-01 00:00:00
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更新日期:2009-10-01 00:00:00
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更新日期:2019-05-01 00:00:00
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更新日期:2017-10-01 00:00:00
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更新日期:2011-11-01 00:00:00
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更新日期:2020-04-01 00:00:00
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更新日期:2005-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-10-01 00:00:00