Abstract:
OBJECTIVE:Mortality on medical intensive care units (ICU) is approximately 25%. It is associated with age, severity of illness, and comorbidities. Preexisting depression is a risk factor for worse outcome in many diseases. The impact of depression on outcome of ICU patients has not been investigated. We assessed a possible association between mortality and preexisting depressive mood at the time of ICU admission. The primary end point was 28-day mortality. METHODS:This single-center cohort study was conducted in a tertiary medical ICU. Two hundred patients were evaluated for preexisting depressive mood at ICU admission, determined by Hospital Anxiety and Depression Scale (HADS) score ≥8 in the depression dimension in patients with appropriate cognitive function. Patients with insufficient cognitive function were assessed using observer rating by next of kin by Hammond scale (cutoff ≥4) and/or a modified version of the Hospital Anxiety and Depression Scale for observer rating (cutoff ≥10). RESULTS:In total, 66 (33%) of 200 patients were classified with preexisting depressive mood. Forty-nine (24.5%) of 200 patients had died by day 28. Of these, 23 (47%) had preexisting depressive mood as compared with 43 of 151 (29%) 28-day survivors (p = .017). Multiple logistic regression analysis revealed that preexisting depressive mood at the time of ICU admission is an independent risk factor for 28-day (odds ratio = 2.2, 95% confidence interval = 1.08-4.5, p = .030) and in-hospital mortality (median time till death = 20.5 [2-186] days, odds ratio = 2.58, 95% confidence interval = 1.31-5.1, p = .006). CONCLUSION:Preexisting depressive mood might be an independent risk factor for 28-day mortality in medical ICU patients. This could have diagnostic and therapeutic implications for critically ill patients.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Wewalka M,Warszawska J,Strunz V,Kitzberger R,Holzinger U,Fuhrmann V,Zauner C,Miehsler W,Moser Gdoi
10.1097/PSY.0000000000000137subject
Has Abstractpub_date
2015-02-01 00:00:00pages
106-13issue
2eissn
0033-3174issn
1534-7796journal_volume
77pub_type
杂志文章abstract::Thirty adults willing their body at death to medical science were compared on a number of personality variables with 30 nondonors, both groups equated for age, education, and socioeconomic status. Donors are internally directed, masters of their fate; nondonors rely on chance or luck to explain outcome. A more defin...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197507000-00004
更新日期:1975-07-01 00:00:00
abstract:OBJECTIVE:Depression has been associated with increased risk of heart failure (HF). Because anxiety is highly comorbid with depression, we sought to establish if anxiety, depression, or their co-occurrence is associated with incident HF. METHODS:A retrospective cohort (N = 236,079) including Veteran's Administration p...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000027
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:Numerous theories have proposed that acute and chronic stressors may exert a cumulative effect on life-span health by causing biological "wear and tear," or allostatic load, which in turn promotes disease. Very few studies have directly tested such models, though, partly because of the challenges associated w...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000534
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To evaluate whether phobic anxiety is associated with increased risk of cardiac mortality in individuals with established coronary heart disease (CHD) and to examine the role of reduced heart rate variability (HRV) in mediating this risk. Previous findings suggest that phobic anxiety may pose increased risk ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181e9f357
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:Despite its simplicity, single-item measures of self-rated health have been associated with mortality independent of objective health conditions. However, little is known about the mechanisms potentially responsible for such associations. This study tested the association between self-rated heath and inflamma...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000683
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:To determine whether the relationship between interleukin (IL)-6 and depressive symptoms is moderated by participation in moderate-intensity physical activity in a sample of primary care patients. Elevated inflammation has been associated with a number of poor health outcomes. Depressive symptoms may be relat...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182108412
更新日期:2011-04-01 00:00:00
abstract::Tetrahydrocortisol (H4F) and tetrahydrocortisone (H4E) were determined for a group of 15 depressed patients and 25 normal controls following the administration of cortisol-4-C14. The ratio, H4F/H4E, was significantly greater for the depressed patients than for the normal controls (P less than 0.001), although the sum ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197601000-00003
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVE:The protective effects of female gender on the appearance and course of coronary heart disease (CHD) in nondiabetic subjects are diminished in the presence of diabetes. Depression predicts onset of and poor outcome from CHD in nondiabetic populations. We hypothesized that the doubled rates of depression in fe...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000041624.96580.1f
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:The objectives of this study were to test the hypothesis that high job demands and low job control (job strain) are associated with elevated free cortisol levels early in the working day and with reduced variability across the day and to evaluate the contribution of anger expression to this pattern. METHODS:...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200003000-00022
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:Despite the abundant literature on the consequences of intimate partner violence (IPV) on mental health, psychological abuse has rarely been considered, and the separate effects of the different types of IPV have been understudied. The aim of this study was to analyze the association between physical, psychol...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000181269.11979.cd
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To examine the cross-sectional association between hostility and measures of abdominal fat (visceral, subcutaneous) in middle-aged African American and white women. Because fat-patterning characteristics are known to differ by race, we were particularly interested in examining whether these associations were ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181ad13a7
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between hostility and biological risk factors for coronary heart disease (CHD) in a population of white European and South Asian men and women living in the United Kingdom. METHODS:This cross-sectional study involved a community-based sample of 1,757 healthy white and South Asian ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181fd944c
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to assess the role of psychological stress in the expression of illness among infected subjects and to test the plausibility of local proinflammatory cytokine production as a pathway linking stress to illness. METHODS:After completing a measure of psychological stress, 55 subject...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199903000-00009
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:A previous study suggested that insulin metabolic variables play a role in the progression of atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) rabbits. The present study sought to determine: 1) if young, individually caged WHHLs are insulin-resistant relative to New Zealand white (NZW) rabbits and ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000155674.95497.ab
更新日期:2005-03-01 00:00:00
abstract::Denial may be adaptive during hospitalization for acute coronary disease. We studied the impact of denial in 48 patients referred to a tertiary care center for treatment of unstable angina. Using the Hackett-Cassem Denial Scale, we divided the group into 25 high deniers and 23 low deniers. The two groups were comparab...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198901000-00003
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to evaluate whether individuals with somatic symptom disorder (SSD) display increased resting-state functional connectivity (FC) within and between the sensorimotor network (SMN), default mode network (DMN), salience network, and dorsal attention network (DAN). METHODS:Eighteen patie...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000681
更新日期:2019-04-01 00:00:00
abstract::The differential relationship between specific subtypes of premenstrual changes and specific subtypes of mental disorder was studied. Premenstrual changes were evaluated with the Premenstrual Assessment Form, which provides specific criteria for the classification of the various subtypes of premenstrual change. The Re...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198112000-00008
更新日期:1981-12-01 00:00:00
abstract:OBJECTIVES:To determine if: 1) depressed patients with a recent acute myocardial infarction (AMI) have higher nighttime heart rate (HR) than nondepressed patients, and 2) elevated nighttime HR is associated with decreased survival post AMI. Depression is a risk factor for mortality post AMI. It is also associated with ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181835ca3
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:The John Henryism hypothesis proposes that high-effort, active coping in impoverished, low-resource environments is associated with an increased risk of cardiovascular disease, but a lower risk of disease in a high-resource environment. To test this hypothesis, we examined the association of John Henryism Act...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000308
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:Prior attempts to measure psychological responses to exercise are potentially limited by a failure to account for participants' expectations, the absence of a valid exercise placebo, and demand characteristics. The purpose of this study was to explore the main and interactive effects of a manipulation designe...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000381
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVES:Exposure to child abuse (CA) is associated with an increased risk of developing asthma and allergies; it is unknown if that risk is present across generations. This study investigated if 2-year-old children born to mothers with a history of CA were at an increased risk of receiving a diagnosis of asthma or a...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000419
更新日期:2016-11-01 00:00:00
abstract::Thirty-five consecutive patients with Cushing's syndrome were studied prospectively prior to treatment. A consistent constellation of psychiatric disturbances was found, including impairments in affect (depressed mood and crying), cognitive functions (decreased concentration and memory), and vegetative functions (decr...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198102000-00002
更新日期:1981-02-01 00:00:00
abstract:OBJECTIVE:To examine whether socioeconomic status (SES) (education, occupation, income), is associated both cross sectionally and prospectively with circulating concentrations of a) two correlates of oxidative damage, F(2)-isoprostanes (F(2)-IsoPs) and gamma-glutamyltransferase (GGT); and b) antioxidant nutrients (asco...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31819e7526
更新日期:2009-06-01 00:00:00
abstract::Aerobic fitness is associated with numerous physiological adaptations which permit physical stress to be coped with more efficiently. The present experiment examined whether aerobic fitness influences emotional response. Heart rate, biochemical measures (catecholamines, cortisol, prolactin, lactic acid), and self-repo...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198306000-00003
更新日期:1983-06-01 00:00:00
abstract:OBJECTIVE:The new DSM-5 somatic symptom disorder was introduced to improve the diagnosis of persons experiencing what used to be called somatoform disorders. So far, it is unclear whether existing self-report measures are useful to detect the new somatic symptom disorder. This study investigates the diagnostic accuracy...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000530
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to test the hypothesis that higher childhood cognitive ability is associated with reduced risk of decline in physical capability in late midlife. METHODS:Participants were 1954 men and women from the Medical Research Council National Survey of Health and Development with complete dat...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000482
更新日期:2017-09-01 00:00:00
abstract::The Rosenberg Self-Esteem Scale, Beck Depression Inventory, and Sullivan Diabetic Adjustment Scale were administered to 105 adolescent girls with diabetes. Results indicate that levels of self-esteem and depression highly correlate with the level of adjustment as assessed on the Diabetic Adjustment Scale (DAS). That i...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197903000-00006
更新日期:1979-03-01 00:00:00
abstract::Negative affectivity (NA) and repressive coping (REP) are coping styles characterized by a disposition to either experience or avoid distress. This study investigated the potential influence of NA and REP on self-reported distress and coronary-prone behavior among 178 male cardiac patients undergoing rehabilitation. B...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199109000-00005
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:Several studies have shown that psychiatric disorders can be associated with venous thromboembolism (VTE) risk, that is, pulmonary embolism (PE) and/or deep vein thrombosis (DVT). In this study, we provide a systematic review and meta-analyses of the studies addressing this issue. METHODS:All studies address...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000863
更新日期:2020-11-01 00:00:00
abstract::We studied 572 men and women who participated in a blood pressure screening program at a government unemployment office. Before having their blood pressures taken, the subjects completed a brief questionnaire that included two items measuring conflict over anger expression. Information was also obtained on obesity, ra...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198607000-00005
更新日期:1986-07-01 00:00:00