Abstract:
OBJECTIVES:To determine if: 1) depressed patients with a recent acute myocardial infarction (AMI) have higher nighttime heart rate (HR) than nondepressed patients, and 2) elevated nighttime HR is associated with decreased survival post AMI. Depression is a risk factor for mortality post AMI. It is also associated with sleep disturbances and with elevated HR, which may be more pronounced at night. Resting and 24-hour HR have been found to predict mortality in patient and community samples. METHODS:Ambulatory electrocardiographic data were obtained from 333 depressed patients and 383 nondepressed patients with recent AMI. They were followed for up to 30 months (median = 24 months). RESULTS:Depressed patients had higher nighttime HR (70.7 +/- 0.7 versus 67.7 +/- 0.6 beats per minute (bpm); p = .001), and daytime HR (76.4 +/- 0.7 versus 74.2 +/- 0.6 bpm; p = .02) than nondepressed patients, even after adjusting for potential confounds. Depression (hazard ratio (Haz R) = 2.19; p = .02) and nighttime HR (Haz R = 1.03; p = .004), but not daytime HR, predicted survival after adjusting for other major predictors and for each other. The interaction between nighttime HR and depression on survival approached, but did not achieve, significance (p = .08). CONCLUSIONS:Mean day and nighttime HR values are higher in depressed patients than in nondepressed patients post AMI. Depression and elevated nighttime HR, but not daytime HR, are independent predictors of survival in these patients. Although depressed patients have a higher nighttime HR than nondepressed patients, nighttime HR predicts mortality in both depressed and nondepressed patients.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Carney RM,Steinmeyer B,Freedland KE,Blumenthal JA,Stein PK,Steinhoff WA,Howells WB,Berkman LF,Watkins LL,Czajkowski SM,Domitrovich PP,Burg MM,Hayano J,Jaffe ASdoi
10.1097/PSY.0b013e3181835ca3subject
Has Abstractpub_date
2008-09-01 00:00:00pages
757-63issue
7eissn
0033-3174issn
1534-7796pii
PSY.0b013e3181835ca3journal_volume
70pub_type
杂志文章abstract::The Adolescent Structured Interview (ASI), adapted from the interview that assesses Type A behavior of adults, was administered to 204 adolescents. These adolescents also completed a battery of self-report questionnaires that measured the three major components of Pattern A: competitive achievement-striving, speed and...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198108000-00004
更新日期:1981-08-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199509000-00011
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journal_title:Psychosomatic medicine
pub_type: 评论,社论
doi:10.1097/PSY.0000000000000339
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journal_title:Psychosomatic medicine
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更新日期:2003-11-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198701000-00004
更新日期:1987-01-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181921b1f
更新日期:2009-04-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198905000-00003
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journal_title:Psychosomatic medicine
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doi:10.1097/00006842-199801000-00013
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000088595.91705.c5
更新日期:2003-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/PSY.0000000000000643
更新日期:2019-01-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199609000-00011
更新日期:1996-09-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/PSY.0b013e31815b5cf6
更新日期:2007-12-01 00:00:00
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doi:10.1097/PSY.0000000000000370
更新日期:2017-02-01 00:00:00
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doi:10.1097/PSY.0000000000000734
更新日期:2019-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/PSY.0000000000000587
更新日期:2018-11-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318246dffb
更新日期:2012-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/01.psy.0000160464.63264.5d
更新日期:2005-05-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199107000-00003
更新日期:1991-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/PSY.0000000000000603
更新日期:2018-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
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更新日期:1991-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181a6177c
更新日期:2009-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 评论,杂志文章
doi:10.1097/PSY.0000000000000682
更新日期:2019-04-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000459
更新日期:2017-10-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-07-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-11-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182359808
更新日期:2011-11-01 00:00:00
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journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000063
更新日期:2014-06-01 00:00:00